| 2013 |
|
Kasahara, Kousuke; Goto, Hidemasa; Izawa, Ichiro; Kiyono, Tohru; Watanabe, Nobumoto; Elowe, Sabine; Nigg, Erich A; Inagaki, Masaki (2013). PI 3-kinase-dependent phosphorylation of Plk1-Ser99 promotes association with 14-3-3γ and is required for metaphase-anaphase transition. Nature communications, 4, 1882.
|
|
Sonnen, Katharina F; Gabryjonczyk, Anna-Maria; Anselm, Eduard; Stierhof, York-Dieter; Nigg, Erich A (2013). Human Cep192 and Cep152 cooperate in Plk4 recruitment and centriole duplication. Journal of cell science, , 37.
|
|
von Schubert, Conrad; Nigg, Erich A (2013). Polo-like kinases. Current biology : CB, 23(6), R225-7.
|
| 2012 |
|
Holland, Andrew J; Fachinetti, Daniele; Zhu, Quan; Bauer, Manuel; Verma, Inder M; Nigg, Erich A; Cleveland, Don W (2012). The autoregulated instability of Polo-like kinase 4 limits centrosome duplication to once per cell cycle. Genes & development, 26(24), 2684-9.
|
|
Kleylein-Sohn, Julia; Pöllinger, Bernadette; Ohmer, Michaela; Nigg, Erich A; Hemmings, Brian A; Wartmann, Markus (2012). Acentrosomal spindle organization renders cancer cells dependent on the kinesin HSET. Journal of cell science, , 38.
|
|
Kaulich, Manuel; Cubizolles, Fabien; Nigg, Erich A (2012). On the regulation, function, and localization of the DNA-dependent ATPase PICH. Chromosoma, , 14.
|
|
Jeyaprakash, A Arockia; Santamaria, Anna; Jayachandran, Uma; Chan, Ying Wai; Benda, Christian; Nigg, Erich A; Conti, Elena (2012). Structural and Functional Organization of the Ska Complex, a Key Component of the Kinetochore-Microtubule Interface. Molecular cell, , 13.
|
|
Rojas, Ana M; Santamaria, Anna; Malik, Rainer; Jensen, Thomas Skøt; Körner, Roman; Morilla, Ian; de Juan, David; Krallinger, Martin; Hansen, Daniel Aaen; Hoffmann, Robert; Lees, Jonathan; Reid, Adam; Yeats, Corin; Wehner, Anja; Elowe, Sabine; Clegg, Andrew B; Brunak, Søren; Nigg, Erich A; Orengo, Christine; Valencia, Alfonso; Ranea, Juan A G (2012). Uncovering the molecular machinery of the human spindle-an integration of wet and dry systems biology. PloS one, 7(3), e31813.
|
|
Sonnen, Katharina F.; Schermelleh, Lothar; Leonhardt, Heinrich; Nigg, Erich A. (2012). 3D-structured illumination microscopy provides novel insight into architecture of human centrosomes. Biology Open, , 12.
|
|
Arquint, Christian; Sonnen, Katharina F; Stierhof, York-Dieter; Nigg, Erich A (2012). Cell-cycle-regulated expression of STIL controls centriole number in human cells. Journal of cell science, 125, 1-11.
|
|
Fairley, Jennifer A; Mitchell, Louise E; Berg, Tracy; Kenneth, Niall S; von Schubert, Conrad; Silljé, Herman H W; Medema, René H; Nigg, Erich A; White, Robert J (2012). Direct Regulation of tRNA and 5S rRNA Gene Transcription by Polo-like Kinase 1. Molecular cell, , 12.
|
| 2011 |
|
Nigg, Erich A; Stearns, Tim (2011). The centrosome cycle: Centriole biogenesis, duplication and inherent asymmetries. Nature cell biology, 13(10), 1154-60.
|
|
Fava, Luca L; Kaulich, Manuel; Nigg, Erich A; Santamaria, Anna (2011). Probing the in vivo function of Mad1:C-Mad2 in the spindle assembly checkpoint. The EMBO journal, 30(16), 3322-36.
|
|
Alexander, J.; Lim, D.; Joughin, B.A.; Hegemann, B.; Hutchins, J.R.A.; Ehrenberger, T.; Ivins, F.; Sessa, F.; Hudecz, O.; Nigg, E.A.; Fry, A.M.; Musacchio, A.; Stukenberg, P.T.; Mechtler, K.; Peters, J.-M.; Smerdon, S.J.; Yaffe, M.B. (2011). Spatial exclusivity combined with positive and negative selection of phosphorylation motifs is the basis for context-dependent mitotic signaling. Science Signaling, 4(179), ra42.
|
|
Dou, von Schubert (2011). Quantitative Mass Spectrometry Analysis Reveals Similar Substrate Consensus Motif for Human Mps1 Kinase and Plk1. PLoS ONE, 6(4), 18793.
|
|
Jakobsen, L.; Vanselow, K.; Skogs, M.; Toyoda, Y.; Lundberg, E.; Poser, I.; Falkenby, L.G.; Bennetzen, M.; Westendorf, J.; Nigg, E.A.; Uhlen, M.; Hyman, A.A.; Andersen, J.S. (2011). Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods. The EMBO Journal,
|
|
Santamaria, A.; Wang, B.; Elowe, S.; Malik, R.; Zhang, F.; Bauer, M.; Schmidt, A.; Sillje, H.H.; Koerner, R.; Nigg, E.A. (2011). The Plk1-dependent phosphoproteome of the early mitotic spindle. Molecular & Cellular Proteomics : MCP, 10(1)
|
| 2010 |
|
von Schubert, C.; Xue, G.; Schmuckli-Maurer, J.; Woods, K.L.; Nigg, E.A.; Dobbelaere, D.A.E. (2010). The transforming parasite Theileria co-opts host cell mitotic and central spindles to persist in continuously dividing cells. PLoS Biology, 8(9)
|
|
Guderian, G.; Westendorf, J.; Uldschmid, A.; Nigg, E.A. (2010). Plk4 trans-autophosphorylation regulates centriole number by controlling betaTrCP-mediated degradation. Journal of Cell Science, 123(Pt 13), 2163-2169.
|
|
Wang, L.H.-C.; Mayer, B.; Stemmann, O.; Nigg, E.A. (2010). Centromere DNA decatenation depends on cohesin removal and is required for mammalian cell division. Journal of Cell Science, 123(Pt 5), 806-813.
|
|
Dulla, K.; Daub, H.; Hornberger, R.; Nigg, E.A.; Korner, R. (2010). Quantitative site-specific phosphorylation dynamics of human protein kinases during mitotic progression. Molecular & Cellular Proteomics : MCP, 9(6), 1167-1181.
|
|
Malik, R.; Dulla, K.; Nigg, E.A.; Korner, R. (2010). From proteome lists to biological impact tools and strategies for the analysis of large MS data sets. Proteomics,
|
|
Olsen, J.V.; Vermeulen, M.; Santamaria, A.; Kumar, C.; Miller, M.L.; Jensen, L.J.; Gnad, F.; Cox, J.; Jensen, T.S.; Nigg, E.A.; Brunak, S.; Mann, M. (2010). Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. Science Signaling, 3(104), ra3.
|
|
Elowe, S.; Dulla, K.; Uldschmid, A.; Li, X.; Dou, Z.; Nigg, E.A. (2010). Uncoupling of the spindle-checkpoint and chromosome-congression functions of BubR1. Journal of Cell Science, 123(Pt 1), 84-94.
|
|
Hubner, N.C.; Wang, L.H.; Kaulich, M.; Descombes, P.; Poser, I.; Nigg, E.A. (2010). Re-examination of siRNA specificity questions role of PICH and Tao1 in the spindle checkpoint and identifies Mad2 as a sensitive target for small RNAs. Chromosoma, 119(2), 149-165.
|
| 2009 |
|
Nigg, Erich A; Raff, Jordan W (2009). Centrioles, centrosomes, and cilia in health and disease. Cell, 139(4), 663-78.
|
|
Klein, Ulf R; Nigg, Erich A (2009). SUMO-dependent regulation of centrin-2. Journal of cell science, 122(Pt 18), 3312-21.
|
|
Malik, Rainer; Lenobel, René; Santamaria, Anna; Ries, Albert; Nigg, Erich A; Körner, Roman (2009). Quantitative analysis of the human spindle phosphoproteome at distinct mitotic stages. Journal of proteome research, 8(10), 4553-63.
|
|
Schmidt, Thorsten I; Kleylein-Sohn, Julia; Westendorf, Jens; Le Clech, Mikael; Lavoie, Sébastien B; Stierhof, York-Dieter; Nigg, Erich A (2009). Control of Centriole Length by CPAP and CP110. Current biology : CB, X, X.
|
|
Chan, Ying Wai; Fava, Luca L; Uldschmid, Andreas; Schmitz, Michael H A; Gerlich, Daniel W; Nigg, Erich A; Santamaria, Anna (2009). Mitotic control of kinetochore-associated dynein and spindle orientation by human Spindly. The Journal of cell biology, 185(5), 859-74.
|
|
Klein, Ulf R; Haindl, Markus; Nigg, Erich A; Muller, Stefan (2009). RanBP2 and SENP3 function in a mitotic SUMO2/3 conjugation-deconjugation cycle on Borealin. Molecular biology of the cell, 20(1), 410-8.
|
|
Gaitanos, Thomas N; Santamaria, Anna; Jeyaprakash, A Arockia; Wang, Bin; Conti, Elena; Nigg, Erich A (2009). Stable kinetochore-microtubule interactions depend on the Ska complex and its new component Ska3/C13Orf3. The EMBO journal, X, X.
|
| 2008 |
|
Wang, Bin; Malik, Rainer; Nigg, Erich; Körner, Roman (2008). Evaluation of the Low-Specificity Protease Elastase for Large-Scale Phosphoproteome Analysis. Analytical chemistry, X, X.
|
|
Chan, Eunice H Y; Santamaria, Anna; Silljé, Herman H W; Nigg, Erich A (2008). Plk1 regulates mitotic Aurora A function through betaTrCP-dependent degradation of hBora. Chromosoma, 117(5), 457-69.
|
|
Santamaria, Anna; Nagel, Susanna; Sillje, Herman H W; Nigg, Erich A (2008). The spindle protein CHICA mediates localization of the chromokinesin Kid to the mitotic spindle. Current biology : CB, 18(10), 723-9.
|
|
Malik, Rainer; Nigg, Erich A; Körner, Roman (2008). Comparative conservation analysis of the human mitotic phosphoproteome. Bioinformatics (Oxford, England), 24(12), 1426-32.
|
|
Wang, Lily Hui-Ching; Schwarzbraun, Thomas; Speicher, Michael R; Nigg, Erich A (2008). Persistence of DNA threads in human anaphase cells suggests late completion of sister chromatid decatenation. Chromosoma, 117(2), 123-35.
|
| 2007 |
|
Baumann, Christoph; Körner, Roman; Hofmann, Kay; Nigg, Erich A (2007). PICH, a centromere-associated SNF2 family ATPase, is regulated by Plk1 and required for the spindle checkpoint. Cell, 128(1), 101-14.
|
|
Graser, Susanne; Stierhof, York-Dieter; Nigg, Erich A (2007). Cep68 and Cep215 (Cdk5rap2) are required for centrosome cohesion. Journal of cell science, 120(Pt 24), 4321-31.
|
|
Jeyaprakash, A Arockia; Klein, Ulf R; Lindner, Doris; Ebert, Judith; Nigg, Erich A; Conti, Elena (2007). Structure of a Survivin-Borealin-INCENP core complex reveals how chromosomal passengers travel together. Cell, 131(2), 271-85.
|
|
Graser, Susanne; Stierhof, York-Dieter; Lavoie, Sébastien B; Gassner, Oliver S; Lamla, Stefan; Le Clech, Mikael; Nigg, Erich A (2007). Cep164, a novel centriole appendage protein required for primary cilium formation. The Journal of cell biology, 179(2), 321-30.
|
|
Elowe, Sabine; Hümmer, Stefan; Uldschmid, Andreas; Li, Xiuling; Nigg, Erich A (2007). Tension-sensitive Plk1 phosphorylation on BubR1 regulates the stability of kinetochore microtubule interactions. Genes & development, 21(17), 2205-19.
|
|
Kleylein-Sohn, Julia; Westendorf, Jens; Le Clech, Mikael; Habedanck, Robert; Stierhof, York-Dieter; Nigg, Erich A (2007). Plk4-induced centriole biogenesis in human cells. Developmental cell, 13(2), 190-202.
|
|
Santamaria, Anna; Neef, Rüdiger; Eberspächer, Uwe; Eis, Knut; Husemann, Manfred; Mumberg, Dominik; Prechtl, Stefan; Schulze, Volker; Siemeister, Gerhard; Wortmann, Lars; Barr, Francis A; Nigg, Erich A (2007). Use of the novel Plk1 inhibitor ZK-thiazolidinone to elucidate functions of Plk1 in early and late stages of mitosis. Molecular biology of the cell, 18(10), 4024-36.
|
|
Thein, Kerstin H; Kleylein-Sohn, Julia; Nigg, Erich A; Gruneberg, Ulrike (2007). Astrin is required for the maintenance of sister chromatid cohesion and centrosome integrity. The Journal of cell biology, 178(3), 345-54.
|
|
Ray-Gallet, Dominique; Quivy, Jean-Pierre; Silljé, Herman W W; Nigg, Erich A; Almouzni, Geneviève (2007). The histone chaperone Asf1 is dispensable for direct de novo histone deposition in Xenopus egg extracts. Chromosoma, 116(5), 487-96.
|
|
Duensing, A; Liu, Y; Perdreau, S A; Kleylein-Sohn, J; Nigg, E A; Duensing, S (2007). Centriole overduplication through the concurrent formation of multiple daughter centrioles at single maternal templates. Oncogene, 26(43), 6280-8.
|
|
Nigg, Erich A (2007). Centrosome duplication: of rules and licenses. Trends in cell biology, 17(5), 215-21.
|
|
Neef, Rüdiger; Gruneberg, Ulrike; Kopajtich, Robert; Li, Xiuling; Nigg, Erich A; Sillje, Herman; Barr, Francis A (2007). Choice of Plk1 docking partners during mitosis and cytokinesis is controlled by the activation state of Cdk1. Nature cell biology, 9(4), 436-44.
|
|
Hergovich, Alexander; Lamla, Stefan; Nigg, Erich A; Hemmings, Brian A (2007). Centrosome-associated NDR kinase regulates centrosome duplication. Molecular cell, 25(4), 625-34.
|
| 2006 |
|
Nigg, Erich A: Cell biology: a licence for duplication, in: Nature 442, 2006, H. 7105, S. X.
|
|
Hanisch, Anja; Silljé, Herman H W; Nigg, Erich A (2006). Timely anaphase onset requires a novel spindle and kinetochore complex comprising Ska1 and Ska2. The EMBO journal, 25(23), 5504-15.
|
|
Nigg, Erich A (2006). Origins and consequences of centrosome aberrations in human cancers. International journal of cancer. Journal international du cancer, 119(12), 2717-23.
|
|
Chalamalasetty, Ravindra B; Hümmer, Stefan; Nigg, Erich A; Silljé, Herman H W (2006). Influence of human Ect2 depletion and overexpression on cleavage furrow formation and abscission. Journal of cell science, 119(Pt 14), 3008-19.
|
|
Mikolajka, Aleksandra; Yan, Xiumin; Popowicz, Grzegorz M; Smialowski, Pawel; Nigg, Erich A; Holak, Tad A (2006). Structure of the N-terminal domain of the FOP (FGFR1OP) protein and implications for its dimerization and centrosomal localization. Journal of molecular biology, 359(4), 863-75.
|
|
Sayer, John A; Otto, Edgar A; O'Toole, John F; Nurnberg, Gudrun; Kennedy, Michael A; Becker, Christian; Hennies, Hans Christian; Helou, Juliana; Attanasio, Massimo; Fausett, Blake V; Utsch, Boris; Khanna, Hemant; Liu, Yan; Drummond, Iain; Kawakami, Isao; Kusakabe, Takehiro; Tsuda, Motoyuki; Ma, Li; Lee, Hwankyu; Larson, Ronald G; Allen, Susan J; Wilkinson, Christopher J; Nigg, Erich A; Shou, Chengchao; Lillo, Concepcion; Williams, David S; Hoppe, Bernd; Kemper, Markus J; Neuhaus, Thomas; Parisi, Melissa A; Glass, Ian A; Petry, Marianne; Kispert, Andreas; Gloy, Joachim; Ganner, Athina; Walz, Gerd; Zhu, Xueliang; Goldman, Daniel; Nurnberg, Peter; Swaroop, Anand; Leroux, Michel R; Hildebrandt, Friedhelm (2006). The centrosomal protein nephrocystin-6 is mutated in Joubert syndrome and activates transcription factor ATF4. Nature genetics, 38(6), 674-81.
|
|
Silljé, Herman H W; Nagel, Susanna; Körner, Roman; Nigg, Erich A (2006). HURP is a Ran-importin beta-regulated protein that stabilizes kinetochore microtubules in the vicinity of chromosomes. Current biology : CB, 16(8), 731-42.
|
|
Badouel, Caroline; Körner, Roman; Frank-Vaillant, Marie; Couturier, Anne; Nigg, Erich A; Tassan, Jean-Pierre (2006). M-phase MELK activity is regulated by MPF and MAPK. Cell cycle (Georgetown, Tex.), 5(8), 883-9.
|
|
Klein, Ulf R; Nigg, Erich A; Gruneberg, Ulrike (2006). Centromere targeting of the chromosomal passenger complex requires a ternary subcomplex of Borealin, Survivin, and the N-terminal domain of INCENP. Molecular biology of the cell, 17(6), 2547-58.
|
|
Nousiainen, Marjaana; Silljé, Herman H W; Sauer, Guido; Nigg, Erich A; Körner, Roman (2006). Phosphoproteome analysis of the human mitotic spindle. Proceedings of the National Academy of Sciences of the United States of America, 103(14), 5391-6.
|
|
Schmidt, Andreas; Rauh, Nadine R; Nigg, Erich A; Mayer, Thomas U (2006). Cytostatic factor: an activity that puts the cell cycle on hold. Journal of cell science, 119(Pt 7), 1213-8.
|
|
Gruneberg, Ulrike; Neef, Rüdiger; Li, Xiuling; Chan, Eunice H Y; Chalamalasetty, Ravindra B; Nigg, Erich A; Barr, Francis A (2006). KIF14 and citron kinase act together to promote efficient cytokinesis. The Journal of cell biology, 172(3), 363-72.
|
|
Tachibana, Kiku-e K; Nigg, Erich A (2006). Geminin regulates multiple steps of the chromosome inheritance cycle. Cell cycle (Georgetown, Tex.), 5(2), 151-4.
|
|
Goto, Hidemasa; Kiyono, Tohru; Tomono, Yasuko; Kawajiri, Aie; Urano, Takeshi; Furukawa, Koichi; Nigg, Erich A; Inagaki, Masaki (2006). Complex formation of Plk1 and INCENP required for metaphase-anaphase transition. Nature cell biology, 8(2), 180-7.
|
|
Silljé, Herman H W; Nigg, Erich A (2006). Purification of mitotic spindles from cultured human cells. Methods (San Diego, Calif.), 38(1), 25-8.
|
|
Yan, Xiumin; Habedanck, Robert; Nigg, Erich A (2006). A complex of two centrosomal proteins, CAP350 and FOP, cooperates with EB1 in microtubule anchoring. Molecular biology of the cell, 17(2), 634-44.
|
|
Hanisch, Anja; Wehner, Anja; Nigg, Erich A; Silljé, Herman H W (2006). Different Plk1 functions show distinct dependencies on Polo-Box domain-mediated targeting. Molecular biology of the cell, 17(1), 448-59.
|
| 2005 |
|
Yamaguchi, Tomoya; Goto, Hidemasa; Yokoyama, Tomoya; Silljé, Herman; Hanisch, Anja; Uldschmid, Andreas; Takai, Yasushi; Oguri, Takashi; Nigg, Erich A; Inagaki, Masaki (2005). Phosphorylation by Cdk1 induces Plk1-mediated vimentin phosphorylation during mitosis. The Journal of cell biology, 171(3), 431-6.
|
|
Casenghi, Martina; Barr, Francis A; Nigg, Erich A (2005). Phosphorylation of Nlp by Plk1 negatively regulates its dynein-dynactin-dependent targeting to the centrosome. Journal of cell science, 118(Pt 21), 5101-8.
|
|
Habedanck, Robert; Stierhof, York-Dieter; Wilkinson, Christopher J; Nigg, Erich A (2005). The Polo kinase Plk4 functions in centriole duplication. Nature cell biology, 7(11), 1140-6.
|
|
Bahe, Susanne; Stierhof, York-Dieter; Wilkinson, Christopher J; Leiss, Florian; Nigg, Erich A (2005). Rootletin forms centriole-associated filaments and functions in centrosome cohesion. The Journal of cell biology, 171(1), 27-33.
|
|
Fabbro, Megan; Zhou, Bin-Bing; Takahashi, Mikiko; Sarcevic, Boris; Lal, Preeti; Graham, Mark E; Gabrielli, Brian G; Robinson, Phillip J; Nigg, Erich A; Ono, Yoshitaka; Khanna, Kum Kum (2005). Cdk1/Erk2- and Plk1-dependent phosphorylation of a centrosome protein, Cep55, is required for its recruitment to midbody and cytokinesis. Developmental cell, 9(4), 477-88.
|
|
Tachibana, Kiku-e K; Gonzalez, Michael A; Guarguaglini, Giulia; Nigg, Erich A; Laskey, Ronald A (2005). Depletion of licensing inhibitor geminin causes centrosome overduplication and mitotic defects. EMBO reports, 6(11), 1052-7.
|
|
Rauh, Nadine R; Schmidt, Andreas; Bormann, Jenny; Nigg, Erich A; Mayer, Thomas U (2005). Calcium triggers exit from meiosis II by targeting the APC/C inhibitor XErp1 for degradation. Nature, 437(7061), 1048-52.
|
|
Schmidt, Andreas; Duncan, Peter I; Rauh, Nadine R; Sauer, Guido; Fry, Andrew M; Nigg, Erich A; Mayer, Thomas U (2005). Xenopus polo-like kinase Plx1 regulates XErp1, a novel inhibitor of APC/C activity. Genes & development, 19(4), 502-13.
|
|
Chan, Eunice H Y; Nousiainen, Marjaana; Chalamalasetty, Ravindra B; Schäfer, Anja; Nigg, Erich A; Silljé, Herman H W (2005). The Ste20-like kinase Mst2 activates the human large tumor suppressor kinase Lats1. Oncogene, 24(12), 2076-86.
|
|
Rapley, Joseph; Baxter, Joanne E; Blot, Joelle; Wattam, Samantha L; Casenghi, Martina; Meraldi, Patrick; Nigg, Erich A; Fry, Andrew M (2005). Coordinate regulation of the mother centriole component nlp by nek2 and plk1 protein kinases. Molecular and cellular biology, 25(4), 1309-24.
|
|
Guarguaglini, Giulia; Duncan, Peter I; Stierhof, York D; Holmström, Tim; Duensing, Stefan; Nigg, Erich A (2005). The forkhead-associated domain protein Cep170 interacts with Polo-like kinase 1 and serves as a marker for mature centrioles. Molecular biology of the cell, 16(3), 1095-107.
|
|
Sauer, Guido; Körner, Roman; Hanisch, Anja; Ries, Albert; Nigg, Erich A; Silljé, Herman H W (2005). Proteome analysis of the human mitotic spindle. Molecular & cellular proteomics : MCP, 4(1), 35-43.
|
| 2004 |
|
Krämer, Alwin; Mailand, Niels; Lukas, Claudia; Syljuåsen, Randi G; Wilkinson, Christopher J; Nigg, Erich A; Bartek, Jiri; Lukas, Jiri (2004). Centrosome-associated Chk1 prevents premature activation of cyclin-B-Cdk1 kinase. Nature cell biology, 6(9), 884-91.
|
|
Mishima, Masanori; Pavicic, Visnja; Grüneberg, Ulrike; Nigg, Erich A; Glotzer, Michael (2004). Cell cycle regulation of central spindle assembly. Nature, 430(7002), 908-13.
|
|
Gruneberg, Ulrike; Neef, Rüdiger; Honda, Reiko; Nigg, Erich A; Barr, Francis A (2004). Relocation of Aurora B from centromeres to the central spindle at the metaphase to anaphase transition requires MKlp2. The Journal of cell biology, 166(2), 167-72.
|
|
Gassmann, Reto; Carvalho, Ana; Henzing, Alexander J; Ruchaud, Sandrine; Hudson, Damien F; Honda, Reiko; Nigg, Erich A; Gerloff, Dietlind L; Earnshaw, William C (2004). Borealin: a novel chromosomal passenger required for stability of the bipolar mitotic spindle. The Journal of cell biology, 166(2), 179-91.
|
|
Stucke, Volker M; Baumann, Christoph; Nigg, Erich A (2004). Kinetochore localization and microtubule interaction of the human spindle checkpoint kinase Mps1. Chromosoma, 113(1), 1-15.
|
|
Barr, Francis A; Silljé, Herman H W; Nigg, Erich A (2004). Polo-like kinases and the orchestration of cell division. Nature reviews. Molecular cell biology, 5(6), 429-40.
|
|
Steensgaard, Peter; Garrè, Massimiliano; Muradore, Ivan; Transidico, Pietro; Nigg, Erich A; Kitagawa, Katsumi; Earnshaw, William C; Faretta, Mario; Musacchio, Andrea (2004). Sgt1 is required for human kinetochore assembly. EMBO reports, 5(6), 626-31.
|
|
Meraldi, Patrick; Honda, Reiko; Nigg, Erich A (2004). Aurora kinases link chromosome segregation and cell division to cancer susceptibility. Current opinion in genetics & development, 14(1), 29-36.
|
|
Sasai, Kaori; Katayama, Hiroshi; Stenoien, David L; Fujii, Satoshi; Honda, Reiko; Kimura, Masashi; Okano, Yukio; Tatsuka, Masaaki; Suzuki, Fumio; Nigg, Erich A; Earnshaw, William C; Brinkley, William R; Sen, Subrata (2004). Aurora-C kinase is a novel chromosomal passenger protein that can complement Aurora-B kinase function in mitotic cells. Cell motility and the cytoskeleton, 59(4), 249-63.
|
|
Fletcher, Lynda; Cerniglia, George J; Nigg, Erich A; Yend, Tim J; Muschel, Ruth J (2004). Inhibition of centrosome separation after DNA damage: a role for Nek2. Radiation research, 162(2), 128-35.
|
| 2003 |
|
Silljé, Herman H W; Nigg, Erich A: Signal transduction. Capturing polo kinase, in: Science (New York, N.Y.) 299, 2003, H. 5610, S. X.
|
|
Andersen, Jens S; Wilkinson, Christopher J; Mayor, Thibault; Mortensen, Peter; Nigg, Erich A; Mann, Matthias (2003). Proteomic characterization of the human centrosome by protein correlation profiling. Nature, 426(6966), 570-4.
|
|
Kufer, Thomas A; Nigg, Erich A; Silljé, Herman H W (2003). Regulation of Aurora-A kinase on the mitotic spindle. Chromosoma, 112(4), 159-63.
|
|
Cheng, Kin-Yip; Lowe, Edward D; Sinclair, John; Nigg, Erich A; Johnson, Louise N (2003). The crystal structure of the human polo-like kinase-1 polo box domain and its phospho-peptide complex. The EMBO journal, 22(21), 5757-68.
|
|
Carrera, Pilar; Moshkin, Yuri M; Gronke, Sebastian; Sillje, Herman H W; Nigg, Erich A; Jackle, Herbert; Karch, Francois (2003). Tousled-like kinase functions with the chromatin assembly pathway regulating nuclear divisions. Genes & development, 17(20), 2578-90.
|
|
Krause, Darren R; Jonnalagadda, Jyoti C; Gatei, Magtouf H; Sillje, Herman H W; Zhou, Bin-Bing; Nigg, Erich A; Khanna, Kumkum (2003). Suppression of Tousled-like kinase activity after DNA damage or replication block requires ATM, NBS1 and Chk1. Oncogene, 22(38), 5927-37.
|
|
Neef, Rüdiger; Preisinger, Christian; Sutcliffe, Josephine; Kopajtich, Robert; Nigg, Erich A; Mayer, Thomas U; Barr, Francis A (2003). Phosphorylation of mitotic kinesin-like protein 2 by polo-like kinase 1 is required for cytokinesis. The Journal of cell biology, 162(5), 863-75.
|
|
Honda, Reiko; Körner, Roman; Nigg, Erich A (2003). Exploring the functional interactions between Aurora B, INCENP, and survivin in mitosis. Molecular biology of the cell, 14(8), 3325-41.
|
|
Casenghi, Martina; Meraldi, Patrick; Weinhart, Ulrike; Duncan, Peter I; Körner, Roman; Nigg, Erich A (2003). Polo-like kinase 1 regulates Nlp, a centrosome protein involved in microtubule nucleation. Developmental cell, 5(1), 113-25.
|
|
Gruneberg, Ulrike; Nigg, Erich A (2003). Regulation of cell division: stop the SIN!. Trends in cell biology, 13(4), 159-62.
|
|
Groth, Anja; Lukas, Jiri; Nigg, Erich A; Silljé, Herman H W; Wernstedt, Christer; Bartek, Jiri; Hansen, Klaus (2003). Human Tousled like kinases are targeted by an ATM- and Chk1-dependent DNA damage checkpoint. The EMBO journal, 22(7), 1676-87.
|
|
Jackman, Mark; Lindon, Catherine; Nigg, Erich A; Pines, Jonathon (2003). Active cyclin B1-Cdk1 first appears on centrosomes in prophase. Nature cell biology, 5(2), 143-8.
|
|
Goto, Hidemasa; Yasui, Yoshihiro; Kawajiri, Aie; Nigg, Erich A; Terada, Yasuhiko; Tatsuka, Masaaki; Nagata, Koh-ichi; Inagaki, Masaki (2003). Aurora-B regulates the cleavage furrow-specific vimentin phosphorylation in the cytokinetic process. The Journal of biological chemistry, 278(10), 8526-30.
|
| 2002 |
|
Heitlinger, E; Peter, M; Lustig, A; Villiger, W; Nigg, E A; Aebi, U (2002). The role of the head and tail domain in lamin structure and assembly: analysis of bacterially expressed chicken lamin A and truncated B2 lamins. Journal of structural biology, 108(1), 74-89.
|
|
Meraldi, Patrick; Honda, Reiko; Nigg, Erich A (2002). Aurora-A overexpression reveals tetraploidization as a major route to centrosome amplification in p53-/- cells. The EMBO journal, 21(4), 483-92.
|
|
Wind, Mathias; Kelm, Olaf; Nigg, Erich A; Lehmann, Wolf D (2002). Identification of phosphorylation sites in the polo-like kinases Plx1 and Plk1 by a novel strategy based on element and electrospray high resolution mass spectrometry. Proteomics, 2(11), 1516-23.
|
|
Nigg, Erich A (2002). Centrosome aberrations: cause or consequence of cancer progression?. Nature reviews. Cancer, 2(11), 815-25.
|
|
Martin-Lluesma, Silvia; Stucke, Volker M; Nigg, Erich A (2002). Role of Hec1 in spindle checkpoint signaling and kinetochore recruitment of Mad1/Mad2. Science (New York, N.Y.), 297(5590), 2267-70.
|
|
Gruneberg, Ulrike; Glotzer, Michael; Gartner, Anton; Nigg, Erich A (2002). The CeCDC-14 phosphatase is required for cytokinesis in the Caenorhabditis elegans embryo. The Journal of cell biology, 158(5), 901-14.
|
|
Kufer, Thomas A; Silljé, Herman H W; Körner, Roman; Gruss, Oliver J; Meraldi, Patrick; Nigg, Erich A (2002). Human TPX2 is required for targeting Aurora-A kinase to the spindle. The Journal of cell biology, 158(4), 617-23.
|
|
Mayor, Thibault; Hacker, Ulrike; Stierhof, York-Dieter; Nigg, Erich A (2002). The mechanism regulating the dissociation of the centrosomal protein C-Nap1 from mitotic spindle poles. Journal of cell science, 115(Pt 16), 3275-84.
|
|
Meraldi, P; Nigg, E A (2002). The centrosome cycle. FEBS letters, 521(1-3), 9-13.
|
|
Kelm, Olaf; Wind, Mathias; Lehmann, Wolf D; Nigg, Erich A (2002). Cell cycle-regulated phosphorylation of the Xenopus polo-like kinase Plx1. The Journal of biological chemistry, 277(28), 25247-56.
|
|
Sumara, Izabela; Vorlaufer, Elisabeth; Stukenberg, P Todd; Kelm, Olaf; Redemann, Norbert; Nigg, Erich A; Peters, Jan-Michael (2002). The dissociation of cohesin from chromosomes in prophase is regulated by Polo-like kinase. Molecular cell, 9(3), 515-25.
|
|
Stucke, Volker M; Silljé, Herman H W; Arnaud, Lionel; Nigg, Erich A (2002). Human Mps1 kinase is required for the spindle assembly checkpoint but not for centrosome duplication. The EMBO journal, 21(7), 1723-32.
|
|
Mello, Jill A; Silljé, Herman H W; Roche, Daniele M J; Kirschner, Doris B; Nigg, Erich A; Almouzni, Geneviève (2002). Human Asf1 and CAF-1 interact and synergize in a repair-coupled nucleosome assembly pathway. EMBO reports, 3(4), 329-34.
|
|
Goto, Hidemasa; Yasui, Yoshihiro; Nigg, Erich A; Inagaki, Masaki (2002). Aurora-B phosphorylates Histone H3 at serine28 with regard to the mitotic chromosome condensation. Genes to cells : devoted to molecular & cellular mechanisms, 7(1), 11-7.
|
| 2001 |
|
Meraldi, P; Nigg, E A (2001). Centrosome cohesion is regulated by a balance of kinase and phosphatase activities. Journal of cell science, 114(Pt 20), 3749-57.
|
|
Duncan, P I; Pollet, N; Niehrs, C; Nigg, E A (2001). Cloning and characterization of Plx2 and Plx3, two additional Polo-like kinases from Xenopus laevis. Experimental cell research, 270(1), 78-87.
|
|
Donaldson, M M; Tavares, A A; Hagan, I M; Nigg, E A; Glover, D M (2001). The mitotic roles of Polo-like kinase. Journal of cell science, 114(Pt 13), 2357-8.
|
|
Silljé, H H; Nigg, E A (2001). Identification of human Asf1 chromatin assembly factors as substrates of Tousled-like kinases. Current biology : CB, 11(13), 1068-73.
|
|
Nigg, E A (2001). Mitotic kinases as regulators of cell division and its checkpoints. Nature reviews. Molecular cell biology, 2(1), 21-32.
|
|
Nigg, E A (2001). Cell cycle regulation by protein kinases and phosphatases. Ernst Schering Research Foundation workshop, 1(34), 19-46.
|
|
Araújo, S J; Nigg, E A; Wood, R D (2001). Strong functional interactions of TFIIH with XPC and XPG in human DNA nucleotide excision repair, without a preassembled repairosome. Molecular and cellular biology, 21(7), 2281-91.
|
| 2000 |
|
Pahlavan, G; Polanski, Z; Kalab, P; Golsteyn, R; Nigg, E A; Maro, B (2000). Characterization of polo-like kinase 1 during meiotic maturation of the mouse oocyte. Developmental biology, 220(2), 392-400.
|
|
Mayor, T; Stierhof, Y D; Tanaka, K; Fry, A M; Nigg, E A (2000). The centrosomal protein C-Nap1 is required for cell cycle-regulated centrosome cohesion. The Journal of cell biology, 151(4), 837-46.
|
|
Fry, A M; Mayor, T; Nigg, E A (2000). Regulating centrosomes by protein phosphorylation. Current topics in developmental biology, 49, 291-312.
|
|
Smits, V A; Klompmaker, R; Arnaud, L; Rijksen, G; Nigg, E A; Medema, R H (2000). Polo-like kinase-1 is a target of the DNA damage checkpoint. Nature cell biology, 2(9), 672-6.
|
|
Fry, A M; Descombes, P; Twomey, C; Bacchieri, R; Nigg, E A (2000). The NIMA-related kinase X-Nek2B is required for efficient assembly of the zygotic centrosome in Xenopus laevis. Journal of cell science, 113 ( Pt 11), 1973-84.
|
| 1999 |
|
Meraldi, P; Lukas, J; Fry, A M; Bartek, J; Nigg, E A (1999). Centrosome duplication in mammalian somatic cells requires E2F and Cdk2-cyclin A. Nature cell biology, 1(2), 88-93.
|
|
Silljé, H H; Takahashi, K; Tanaka, K; Van Houwe, G; Nigg, E A (1999). Mammalian homologues of the plant Tousled gene code for cell-cycle-regulated kinases with maximal activities linked to ongoing DNA replication. The EMBO journal, 18(20), 5691-702.
|
|
Mayor, T; Meraldi, P; Stierhof, Y D; Nigg, E A; Fry, A M (1999). Protein kinases in control of the centrosome cycle. FEBS letters, 452(1-2), 92-5.
|
|
Fry, A M; Arnaud, L; Nigg, E A (1999). Activity of the human centrosomal kinase, Nek2, depends on an unusual leucine zipper dimerization motif. The Journal of biological chemistry, 274(23), 16304-10.
|
|
Tanaka, K; Nigg, E A (1999). Cloning and characterization of the murine Nek3 protein kinase, a novel member of the NIMA family of putative cell cycle regulators. The Journal of biological chemistry, 274(19), 13491-7.
|
| 1998 |
|
Marshall, C J; Nigg, E A: Oncogenes and cell proliferation. Cancer genes: lessons from genetics and biochemistry, in: Current opinion in genetics & development 8, 1998, H. 1, S. 2.
|
|
Fry, A M; Meraldi, P; Nigg, E A (1998). A centrosomal function for the human Nek2 protein kinase, a member of the NIMA family of cell cycle regulators. The EMBO journal, 17(2), 470-81.
|
|
Arnaud, L; Pines, J; Nigg, E A (1998). GFP tagging reveals human Polo-like kinase 1 at the kinetochore/centromere region of mitotic chromosomes. Chromosoma, 107(6-7), 424-9.
|
|
Nigg, E A (1998). Polo-like kinases: positive regulators of cell division from start to finish. Current opinion in cell biology, 10(6), 776-83.
|
|
Fry, A M; Mayor, T; Meraldi, P; Stierhof, Y D; Tanaka, K; Nigg, E A (1998). C-Nap1, a novel centrosomal coiled-coil protein and candidate substrate of the cell cycle-regulated protein kinase Nek2. The Journal of cell biology, 141(7), 1563-74.
|
|
Blangy, A; Chaussepied, P; Nigg, E A (1998). Rigor-type mutation in the kinesin-related protein HsEg5 changes its subcellular localization and induces microtubule bundling. Cell motility and the cytoskeleton, 40(2), 174-82.
|
|
Descombes, P; Nigg, E A (1998). The polo-like kinase Plx1 is required for M phase exit and destruction of mitotic regulators in Xenopus egg extracts. The EMBO journal, 17(5), 1328-35.
|
| 1997 |
|
Tanaka, K; Parvinen, M; Nigg, E A (1997). The in vivo expression pattern of mouse Nek2, a NIMA-related kinase, indicates a role in both mitosis and meiosis. Experimental cell research, 237(2), 264-74.
|
|
Mundt, K E; Golsteyn, R M; Lane, H A; Nigg, E A (1997). On the regulation and function of human polo-like kinase 1 (PLK1): effects of overexpression on cell cycle progression. Biochemical and biophysical research communications, 239(2), 377-85.
|
|
Blangy, A; Arnaud, L; Nigg, E A (1997). Phosphorylation by p34cdc2 protein kinase regulates binding of the kinesin-related motor HsEg5 to the dynactin subunit p150. The Journal of biological chemistry, 272(31), 19418-24.
|
|
Nigg, E A (1997). Nucleocytoplasmic transport: signals, mechanisms and regulation. Nature, 386(6627), 779-87.
|
|
Lane, H A; Nigg, E A (1997). Cell-cycle control: POLO-like kinases join the outer circle. Trends in cell biology, 7(2), 63-8.
|
|
Fry, A M; Nigg, E A (1997). Characterization of mammalian NIMA-related kinases. Methods in enzymology, 283, 270-82.
|
| 1996 |
|
Nigg, E A; Blangy, A; Lane, H A (1996). Dynamic changes in nuclear architecture during mitosis: on the role of protein phosphorylation in spindle assembly and chromosome segregation. Experimental cell research, 229(2), 174-80.
|
|
Lane, H A; Nigg, E A (1996). Antibody microinjection reveals an essential role for human polo-like kinase 1 (Plk1) in the functional maturation of mitotic centrosomes. The Journal of cell biology, 135(6 Pt 2), 1701-13.
|
|
Gold, M O; Tassan, J P; Nigg, E A; Rice, A P; Herrmann, C H (1996). Viral transactivators E1A and VP16 interact with a large complex that is associated with CTD kinase activity and contains CDK8. Nucleic acids research. Special publication, 24(19), 3771-7.
|
|
Nigg, E A (1996). Cyclin-dependent kinase 7: at the cross-roads of transcription, DNA repair and cell cycle control?. Current opinion in cell biology, 8(3), 312-7.
|
|
Adamczewski, J P; Rossignol, M; Tassan, J P; Nigg, E A; Moncollin, V; Egly, J M (1996). MAT1, cdk7 and cyclin H form a kinase complex which is UV light-sensitive upon association with TFIIH. The EMBO journal, 15(8), 1877-84.
|
|
Leclerc, V; Tassan, J P; O'Farrell, P H; Nigg, E A; Léopold, P (1996). Drosophila Cdk8, a kinase partner of cyclin C that interacts with the large subunit of RNA polymerase II. Molecular biology of the cell, 7(4), 505-13.
|
|
Golsteyn, R M; Lane, H A; Mundt, K E; Arnaud, L; Nigg, E A (1996). The family of polo-like kinases. Progress in cell cycle research, 2, 107-14.
|
| 1995 |
|
Blangy, A; Lane, H A; d'Hérin, P; Harper, M; Kress, M; Nigg, E A (1995). Phosphorylation by p34cdc2 regulates spindle association of human Eg5, a kinesin-related motor essential for bipolar spindle formation in vivo. Cell, 83(7), 1159-69.
|
|
Zucca, E; Nigg, E A (1995). Cell cycle regulation and the function of cancer genes. Annals of oncology : official journal of the European Society for Medical Oncology / ESMO, 6(10), 975-8.
|
|
Tassan, J P; Jaquenoud, M; Fry, A M; Frutiger, S; Hughes, G J; Nigg, E A (1995). In vitro assembly of a functional human CDK7-cyclin H complex requires MAT1, a novel 36 kDa RING finger protein. The EMBO journal, 14(22), 5608-17.
|
|
Devault, A; Martinez, A M; Fesquet, D; Labbé, J C; Morin, N; Tassan, J P; Nigg, E A; Cavadore, J C; Dorée, M (1995). MAT1 ('menage à trois') a new RING finger protein subunit stabilizing cyclin H-cdk7 complexes in starfish and Xenopus CAK. The EMBO journal, 14(20), 5027-36.
|
|
Ossipow, V; Tassan, J P; Nigg, E A; Schibler, U (1995). A mammalian RNA polymerase II holoenzyme containing all components required for promoter-specific transcription initiation. Cell, 83(1), 137-46.
|
|
Fry, A M; Nigg, E A (1995). Cell cycle. The NIMA kinase joins forces with Cdc2. Current biology : CB, 5(10), 1122-5.
|
|
Tassan, J P; Jaquenoud, M; Léopold, P; Schultz, S J; Nigg, E A (1995). Identification of human cyclin-dependent kinase 8, a putative protein kinase partner for cyclin C. Proceedings of the National Academy of Sciences of the United States of America, 92(19), 8871-5.
|
|
Golsteyn, R M; Mundt, K E; Fry, A M; Nigg, E A (1995). Cell cycle regulation of the activity and subcellular localization of Plk1, a human protein kinase implicated in mitotic spindle function. The Journal of cell biology, 129(6), 1617-28.
|
|
Nigg, E A (1995). Cyclin-dependent protein kinases: key regulators of the eukaryotic cell cycle. BioEssays : news and reviews in molecular, cellular and developmental biology, 17(6), 471-80.
|
|
Fry, A M; Schultz, S J; Bartek, J; Nigg, E A (1995). Substrate specificity and cell cycle regulation of the Nek2 protein kinase, a potential human homolog of the mitotic regulator NIMA of Aspergillus nidulans. The Journal of biological chemistry, 270(21), 12899-905.
|
|
Gallant, P; Fry, A M; Nigg, E A (1995). Protein kinases in the control of mitosis: focus on nucleocytoplasmic trafficking. Journal of cell science. Supplement, 19, 21-8.
|
| 1994 |
|
Roy, R; Adamczewski, J P; Seroz, T; Vermeulen, W; Tassan, J P; Schaeffer, L; Nigg, E A; Hoeijmakers, J H; Egly, J M (1994). The MO15 cell cycle kinase is associated with the TFIIH transcription-DNA repair factor. Cell, 79(6), 1093-101.
|
|
Tassan, J P; Schultz, S J; Bartek, J; Nigg, E A (1994). Cell cycle analysis of the activity, subcellular localization, and subunit composition of human CAK (CDK-activating kinase). The Journal of cell biology, 127(2), 467-78.
|
|
Mäkelä, T P; Tassan, J P; Nigg, E A; Frutiger, S; Hughes, G J; Weinberg, R A (1994). A cyclin associated with the CDK-activating kinase MO15. Nature, 371(6494), 254-7.
|
|
Golsteyn, R M; Schultz, S J; Bartek, J; Ziemiecki, A; Ried, T; Nigg, E A (1994). Cell cycle analysis and chromosomal localization of human Plk1, a putative homologue of the mitotic kinases Drosophila polo and Saccharomyces cerevisiae Cdc5. Journal of cell science, 107 ( Pt 6), 1509-17.
|
|
Schultz, S J; Fry, A M; Sütterlin, C; Ried, T; Nigg, E A (1994). Cell cycle-dependent expression of Nek2, a novel human protein kinase related to the NIMA mitotic regulator of Aspergillus nidulans. Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 5(6), 625-35.
|
|
Hennekes, H; Nigg, E A (1994). The role of isoprenylation in membrane attachment of nuclear lamins. A single point mutation prevents proteolytic cleavage of the lamin A precursor and confers membrane binding properties. Journal of cell science, 107 ( Pt 4), 1019-29.
|
|
Gallant, P; Nigg, E A (1994). Identification of a novel vertebrate cyclin: cyclin B3 shares properties with both A- and B-type cyclins. The EMBO journal, 13(3), 595-605.
|
| 1993 |
|
Maridor, G; Gallant, P; Golsteyn, R; Nigg, E A (1993). Nuclear localization of vertebrate cyclin A correlates with its ability to form complexes with cdk catalytic subunits. Journal of cell science, 106 ( Pt 2), 535-44.
|
|
Schultz, S J; Nigg, E A (1993). Identification of 21 novel human protein kinases, including 3 members of a family related to the cell cycle regulator nimA of Aspergillus nidulans. Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 4(10), 821-30.
|
|
Nigg, E A (1993). Cellular substrates of p34(cdc2) and its companion cyclin-dependent kinases. Trends in cell biology, 3(9), 296-301.
|
|
Schmidt-Zachmann, M S; Dargemont, C; Kühn, L C; Nigg, E A (1993). Nuclear export of proteins: the role of nuclear retention. Cell, 74(3), 493-504.
|
|
Schmidt-Zachmann, M S; Nigg, E A (1993). Protein localization to the nucleolus: a search for targeting domains in nucleolin. Journal of cell science, 105 ( Pt 3), 799-806.
|
|
Nigg, E A (1993). Targets of cyclin-dependent protein kinases. Current opinion in cell biology, 5(2), 187-93.
|
|
Hennekes, H; Peter, M; Weber, K; Nigg, E A (1993). Phosphorylation on protein kinase C sites inhibits nuclear import of lamin B2. The Journal of cell biology, 120(6), 1293-304.
|
| 1992 |
|
Nigg, E A (1992). Assembly and cell cycle dynamics of the nuclear lamina. Seminars in cell biology, 3(4), 245-53.
|
|
Sanghera, J S; Peter, M; Nigg, E A; Pelech, S L (1992). Immunological characterization of avian MAP kinases: evidence for nuclear localization. Molecular biology of the cell, 3(7), 775-87.
|
|
Krek, W; Marks, J; Schmitz, N; Nigg, E A; Simanis, V (1992). Vertebrate p34cdc2 phosphorylation site mutants: effects upon cell cycle progression in the fission yeast Schizosaccharomyces pombe. Journal of cell science, 102 ( Pt 1), 43-53.
|
|
Nigg, E A; Kitten, G T; Vorburger, K (1992). Targeting lamin proteins to the nuclear envelope: the role of CaaX box modifications. Transactions, 20(2), 500-4.
|
|
Krek, W; Nigg, E A (1992). Cell cycle regulation of vertebrate p34cdc2 activity: identification of Thr161 as an essential in vivo phosphorylation site. The New biologist, 4(4), 323-9.
|
|
Peter, M; Sanghera, J S; Pelech, S L; Nigg, E A (1992). Mitogen-activated protein kinases phosphorylate nuclear lamins and display sequence specificity overlapping that of mitotic protein kinase p34cdc2. European journal of biochemistry / FEBS, 205(1), 287-94.
|
|
Gallant, P; Nigg, E A (1992). Cyclin B2 undergoes cell cycle-dependent nuclear translocation and, when expressed as a non-destructible mutant, causes mitotic arrest in HeLa cells. The Journal of cell biology, 117(1), 213-24.
|
|
Nigg, E A (1992). Assembly-disassembly of the nuclear lamina. Current opinion in cell biology, 4(1), 105-9.
|
|
Krek, W; Maridor, G; Nigg, E A (1992). Casein kinase II is a predominantly nuclear enzyme. The Journal of cell biology, 116(1), 43-55.
|
|
Nigg, E A; Gallant, P; Krek, W (1992). Regulation of p34cdc2 protein kinase activity by phosphorylation and cyclin binding. Ciba Foundation symposium, 170, 72-84; discussion 84-96.
|
|
Peter, M; Chavrier, P; Nigg, E A; Zerial, M (1992). Isoprenylation of rab proteins on structurally distinct cysteine motifs. Journal of cell science, 102 ( Pt 4), 857-65.
|
| 1991 |
|
Peter, M; Nigg, E A (1991). Ectopic expression of an A-type lamin does not interfere with differentiation of lamin A-negative embryonal carcinoma cells. Journal of cell science, 100 ( Pt 3), 589-98.
|
|
Krek, W; Nigg, E A (1991). Mutations of p34cdc2 phosphorylation sites induce premature mitotic events in HeLa cells: evidence for a double block to p34cdc2 kinase activation in vertebrates. The EMBO journal, 10(11), 3331-41.
|
|
Nigg, E A (1991). The substrates of the cdc2 kinase. Seminars in cell biology, 2(4), 261-70.
|
|
Bailer, S M; Eppenberger, H M; Griffiths, G; Nigg, E A (1991). Characterization of A 54-kD protein of the inner nuclear membrane: evidence for cell cycle-dependent interaction with the nuclear lamina. The Journal of cell biology, 114(3), 389-400.
|
|
Nigg, E A; Baeuerle, P A; Lührmann, R (1991). Nuclear import-export: in search of signals and mechanisms. Cell, 66(1), 15-22.
|
|
Peter, M; Heitlinger, E; Häner, M; Aebi, U; Nigg, E A (1991). Disassembly of in vitro formed lamin head-to-tail polymers by CDC2 kinase. The EMBO journal, 10(6), 1535-44.
|
|
Heitlinger, E; Peter, M; Häner, M; Lustig, A; Aebi, U; Nigg, E A (1991). Expression of chicken lamin B2 in Escherichia coli: characterization of its structure, assembly, and molecular interactions. The Journal of cell biology, 113(3), 485-95.
|
|
Kitten, G T; Nigg, E A (1991). The CaaX motif is required for isoprenylation, carboxyl methylation, and nuclear membrane association of lamin B2. The Journal of cell biology, 113(1), 13-23.
|
|
Enoch, T; Peter, M; Nurse, P; Nigg, E A (1991). p34cdc2 acts as a lamin kinase in fission yeast. The Journal of cell biology, 112(5), 797-807.
|
|
Maridor, G; Park, W; Krek, W; Nigg, E A (1991). Casein kinase II. cDNA sequences, developmental expression, and tissue distribution of mRNAs for alpha, alpha', and beta subunits of the chicken enzyme. The Journal of biological chemistry, 266(4), 2362-8.
|
|
Krek, W; Nigg, E A (1991). Differential phosphorylation of vertebrate p34cdc2 kinase at the G1/S and G2/M transitions of the cell cycle: identification of major phosphorylation sites. The EMBO journal, 10(2), 305-16.
|
|
Pearson, D; Nigg, E A; Nagamine, Y; Jans, D A; Hemmings, B A (1991). Mechanisms of cAMP-mediated gene induction: examination of renal epithelial cell mutants affected in the catalytic subunit of the cAMP-dependent protein kinase. Experimental cell research, 192(1), 315-8.
|
|
Nigg, E A; Krek, W; Peter, M (1991). Vertebrate cdc2 kinase: its regulation by phosphorylation and its mitotic targets. Cold Spring Harbor symposia on quantitative biology, 56, 539-47.
|
| 1990 |
|
Griffiths, G; Hollinshead, R; Hemmings, B A; Nigg, E A (1990). Ultrastructural localization of the regulatory (RII) subunit of cyclic AMP-dependent protein kinase to subcellular compartments active in endocytosis and recycling of membrane receptors. Journal of cell science, 96 ( Pt 4), 691-703.
|
|
Maridor, G; Krek, W; Nigg, E A (1990). Structure and developmental expression of chicken nucleolin and NO38: coordinate expression of two abundant non-ribosomal nucleolar proteins. Biochimica et biophysica acta, 1049(2), 126-33.
|
|
Peter, M; Nakagawa, J; Dorée, M; Labbé, J C; Nigg, E A (1990). In vitro disassembly of the nuclear lamina and M phase-specific phosphorylation of lamins by cdc2 kinase. Cell, 61(4), 591-602.
|
|
Maridor, G; Nigg, E A (1990). cDNA sequences of chicken nucleolin/C23 and NO38/B23, two major nucleolar proteins. Nucleic acids research. Special publication, 18(5), 1286.
|
|
Peter, M; Nakagawa, J; Dorée, M; Labbé, J C; Nigg, E A (1990). Identification of major nucleolar proteins as candidate mitotic substrates of cdc2 kinase. Cell, 60(5), 791-801.
|
|
Nigg, E A (1990). Mechanisms of signal transduction to the cell nucleus. Advances in cancer research, 55, 271-310.
|
| 1989 |
|
Nigg, E A (1989). The nuclear envelope. Current opinion in cell biology, 1(3), 435-40.
|
|
Borer, R A; Lehner, C F; Eppenberger, H M; Nigg, E A (1989). Major nucleolar proteins shuttle between nucleus and cytoplasm. Cell, 56(3), 379-90.
|
|
Vorburger, K; Kitten, G T; Nigg, E A (1989). Modification of nuclear lamin proteins by a mevalonic acid derivative occurs in reticulocyte lysates and requires the cysteine residue of the C-terminal CXXM motif. The EMBO journal, 8(13), 4007-13.
|
|
Nakagawa, J; Kitten, G T; Nigg, E A (1989). A somatic cell-derived system for studying both early and late mitotic events in vitro. Journal of cell science, 94 ( Pt 3), 449-62.
|
|
Krek, W; Nigg, E A (1989). Structure and developmental expression of the chicken CDC2 kinase. The EMBO journal, 8(10), 3071-8.
|
|
Peter, M; Kitten, G T; Lehner, C F; Vorburger, K; Bailer, S M; Maridor, G; Nigg, E A (1989). Cloning and sequencing of cDNA clones encoding chicken lamins A and B1 and comparison of the primary structures of vertebrate A- and B-type lamins. Journal of molecular biology, 208(3), 393-404.
|
|
Vorburger, K; Lehner, C F; Kitten, G T; Eppenberger, H M; Nigg, E A (1989). A second higher vertebrate B-type lamin. cDNA sequence determination and in vitro processing of chicken lamin B2. Journal of molecular biology, 208(3), 405-15.
|
| 1988 |
|
Stick, R; Angres, B; Lehner, C F; Nigg, E A (1988). The fates of chicken nuclear lamin proteins during mitosis: evidence for a reversible redistribution of lamin B2 between inner nuclear membrane and elements of the endoplasmic reticulum. The Journal of cell biology, 107(2), 397-406.
|
|
Nigg, E A (1988). Nuclear function and organization: the potential of immunochemical approaches. International review of cytology, 110, 27-92.
|
| 1987 |
|
Lehner, C F; Stick, R; Eppenberger, H M; Nigg, E A (1987). Differential expression of nuclear lamin proteins during chicken development. The Journal of cell biology, 105(1), 577-87.
|
| 1986 |
|
Lehner, C F; Kurer, V; Eppenberger, H M; Nigg, E A (1986). The nuclear lamin protein family in higher vertebrates. Identification of quantitatively minor lamin proteins by monoclonal antibodies. The Journal of biological chemistry, 261(28), 13293-301.
|
|
Reuter, R; Lehner, C F; Nigg, E A; Lührmann, R (1986). A monoclonal antibody specific for snRNPs U1 and U2. FEBS letters, 201(1), 25-30.
|
|
Nigg, E A; Sefton, B M; Singer, S J; Vogt, P K (1986). Cytoskeletal organization, vinculin-phosphorylation, and fibronectin expression in transformed fibroblasts with different cell morphologies. Virology, 151(1), 50-65.
|
|
Lehner, C F; Fürstenberger, G; Eppenberger, H M; Nigg, E A (1986). Biogenesis of the nuclear lamina: in vivo synthesis and processing of nuclear protein precursors. Proceedings of the National Academy of Sciences of the United States of America, 83(7), 2096-9.
|
|
Lehner, C F; Eppenberger, H M; Fakan, S; Nigg, E A (1986). Nuclear substructure antigens. Monoclonal antibodies against components of nuclear matrix preparations. Experimental cell research, 162(1), 205-19.
|
| 1985 |
|
Nigg, E A; Hilz, H; Eppenberger, H M; Dutly, F (1985). Rapid and reversible translocation of the catalytic subunit of cAMP-dependent protein kinase type II from the Golgi complex to the nucleus. The EMBO journal, 4(11), 2801-6.
|
|
Nigg, E A; Schäfer, G; Hilz, H; Eppenberger, H M (1985). Cyclic-AMP-dependent protein kinase type II is associated with the Golgi complex and with centrosomes. Cell, 41(3), 1039-51.
|
| 1983 |
|
Nigg, E A; Cooper, J A; Hunter, T (1983). Immunofluorescent localization of a 39,000-dalton substrate of tyrosine protein kinases to the cytoplasmic surface of the plasma membrane. The Journal of cell biology, 96(6), 1601-9.
|
|
Papkoff, J; Nigg, E A; Hunter, T (1983). The transforming protein of Moloney murine sarcoma virus is a soluble cytoplasmic protein. Cell, 33(1), 161-72.
|
| 1982 |
|
Nigg, E A; Walter, G; Singer, S J (1982). On the nature of crossreactions observed with antibodies directed to defined epitopes. Proceedings of the National Academy of Sciences of the United States of America, 79(19), 5939-43.
|
|
Nigg, E A; Sefton, B M; Hunter, T; Walter, G; Singer, S J (1982). Immunofluorescent localization of the transforming protein of Rous sarcoma virus with antibodies against a synthetic src peptide. Proceedings of the National Academy of Sciences of the United States of America, 79(17), 5322-6.
|
|
Sefton, B M; Hunter, T; Nigg, E A; Singer, S J; Walter, G (1982). Cytoskeletal targets for viral transforming proteins with tyrosine protein kinase activity. Cold Spring Harbor symposia on quantitative biology, 46 Pt 2, 939-51.
|
| 1981 |
|
Cherry, R J; Nigg, E A (1981). Rotational diffusion of erythrocyte membrane proteins. Progress in clinical and biological research, 51, 59-77.
|
| 1980 |
|
Nigg, E A; Cherry, R J; Bächi, T (1980). Influence of influenza and Sendai virus on the rotational mobility of Band 3 proteins in human erythrocyte membranes. Virology, 107(2), 552-6.
|
|
Cherry, R J; Nigg, E A; Beddard, G S (1980). Oligosaccharide motion in erythrocyte membranes investigated by picosecond fluorescence polarization and microsecond dichroism of an optical probe. Proceedings of the National Academy of Sciences of the United States of America, 77(10), 5899-903.
|
|
Nigg, E A; Gahmberg, C G; Cherry, R J (1980). Rotational diffusion of band 3 proteins in membranes from En(a-) and neuraminidase-treated normal human erythrocytes. Biochimica et biophysica acta, 600(3), 636-42.
|
|
Nigg, E A; Cherry, R J (1980). Anchorage of a band 3 population at the erythrocyte cytoplasmic membrane surface: protein rotational diffusion measurements. Proceedings of the National Academy of Sciences of the United States of America, 77(8), 4702-6.
|
|
Nigg, E A; Bron, C; Girardet, M; Cherry, R J (1980). Band 3-glycophorin A association in erythrocyte membrane demonstrated by combining protein diffusion measurements with antibody-induced cross-linking. Biochemistry, 19(9), 1887-93.
|
| 1979 |
|
Nigg, E A; Cherry, R J (1979). Influence of temperature and cholesterol on the rotational diffusion of band 3 in the human erythrocyte membrane. Biochemistry, 18(16), 3457-65.
|
|
Nigg, E; Cherry, R J (1979). Dimeric association of band 3 in the erythrocyte membrane demonstrated by protein diffusion measurements. Nature, 277(5696), 493-4.
|
|
Nigg, E; Kessler, M; Cherry, R J (1979). Labeling of human erythrocyte membranes with eosin probes used for protein diffusion measurements: inhibition of anion transport and photo-oxidative inactivation of acetylcholinesterase. Biochimica et biophysica acta, 550(2), 328-40.
|
|
Cherry, R J; Nigg, E (1979). Rotational diffusion of band 3 in the red cell membrane: measurements using triplet probes. Progress in clinical and biological research, 30, 475-81.
|
