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Publication list Prof. Werner Arber  
Arber, W. (2002): Evolution of prokaryotic genomes. Curr Top Microbiol Immunol 264, 1-14.

Arber, W. (2001): Microbiology: impact on research in life sciences. Micron 32, 5-6.

Arber, W. (2000): Genetic variation: molecular mechanisms and impact on microbial evolution. FEMS Microbiol Rev 24, 1-7.

Papadopoulos, D., Schneider, D., Meier-Eiss, J., Arber, W., Lenski, R.E. , and Blot, M. (1999): Genomic evolution during a 10,000-generation experiment with bacteria. Proc Natl Acad Sci U S A 96, 3807-3812.

Casadesus, J., Naas, T., Garzon, A., Arini, A., Torreblanca, J. , and Arber, W. (1999): Lack of hotspot targets: a constraint for IS30 transposition in Salmonella. Gene 238, 231-239.

Arber, W. (1999): Involvement of gene products in bacterial evolution. Ann N Y Acad Sci 870, 36-44.

Olasz, F., Kiss, J., Konig, P., Buzas, Z., Stalder, R. , and Arber, W. (1998): Target specificity of insertion element IS30. Mol Microbiol 28, 691-704.

Iida, S., Hiestand-Nauer, R., Sandmeier, H., Lehnherr, H. , and Arber, W. (1998): Accessory genes in the darA operon of bacteriophage P1 affect antirestriction function, generalized transduction, head morphogenesis, and host cell lysis. Virology 251, 49-58.

Olasz, F., Farkas, T., Stalder, R. , and Arber, W. (1997): Mutations in the carboxy-terminal part of IS30 transposase affect the formation and dissolution of (IS30)2 dimer. FEBS Lett 413, 453-461.

Olasz, F., Farkas, T., Kiss, J., Arini, A. , and Arber, W. (1997): Terminal inverted repeats of insertion sequence IS30 serve as targets for transposition. J Bacteriol 179, 7551-7558.

Arini, A., Keller, M.P. , and Arber, W. (1997): An antisense RNA in IS30 regulates the translational expression of the transposase. Biol Chem 378, 1421-1431.

Szeverenyi, I., Hodel, A., Arber, W. , and Olasz, F. (1996): Vector for IS element entrapment and functional characterization based on turning on expression of distal promoterless genes. Gene 174, 103-110.

Schmidt, C., Velleman, M. , and Arber, W. (1996): Three functions of bacteriophage P1 involved in cell lysis. J Bacteriol 178, 1099-1104.

Rozsa, F.W., Viollier, P., Fussenegger, M., Hiestand-Nauer, R. , and Arber, W. (1995): Cin-mediated recombination at secondary crossover sites on the Escherichia coli chromosome. J Bacteriol 177, 1159-1168.

Naas, T., Blot, M., Fitch, W.M. , and Arber, W. (1995): Dynamics of IS-related genetic rearrangements in resting Escherichia coli K-12. Mol Biol Evol 12, 198-207.

Naas, T., Blot, M., Fitch, W.M. , and Arber, W. (1994): Insertion sequence-related genetic variation in resting Escherichia coli K-12. Genetics 136, 721-730.

Olasz, F., Stalder, R. , and Arber, W. (1993): Formation of the tandem repeat (IS30)2 and its role in IS30-mediated transpositional DNA rearrangements. Mol Gen Genet 239, 177-187.

Blot, M., Heitman, J. , and Arber, W. (1993): Tn5-mediated bleomycin resistance in Escherichia coli requires the expression of host genes. Mol Microbiol 8, 1017-1024.

Arber, W. (1993): Evolution of prokaryotic genomes. Gene 135, 49-56.

Sandmeier, H., Iida, S. , and Arber, W. (1992): DNA inversion regions Min of plasmid p15B and Cin of bacteriophage P1: evolution of bacteriophage tail fiber genes. J Bacteriol 174, 3936-3944.

Lehnherr, H., Velleman, M., Guidolin, A. , and Arber, W. (1992): Bacteriophage P1 gene 10 is expressed from a promoter-operator sequence controlled by C1 and Bof proteins. J Bacteriol 174, 6138-6144.

Lehnherr, H., Guidolin, A. , and Arber, W. (1992): Mutational analysis of the bacteriophage P1 late promoter sequence Ps. J Mol Biol 228, 101-107.

Sandmeier, H., Iida, S., Hubner, P., Hiestand-Nauer, R. , and Arber, W. (1991): Gene organization in the multiple DNA inversion region min of plasmid p15B of E.coli 15T-: assemblage of a variable gene. Nucleic Acids Res 19, 5831-5838.

Lehnherr, H., Guidolin, A. , and Arber, W. (1991): Bacteriophage P1 gene 10 encodes a trans-activating factor required for late gene expression. J Bacteriol 173, 6438-6445.

Blot, M., Meyer, J. , and Arber, W. (1991): Bleomycin-resistance gene derived from the transposon Tn5 confers selective advantage to Escherichia coli K-12. Proc Natl Acad Sci U S A 88, 9112-9116.

Arber, W. (1991): Elements in microbial evolution. J Mol Evol 33, 4-12.

Arber, W. (1991): Contemplations on genes and biological functions. Adv Otorhinolaryngol 46, 1-7.

Stalder, R., Caspers, P., Olasz, F. , and Arber, W. (1990): The N-terminal domain of the insertion sequence 30 transposase interacts specifically with the terminal inverted repeats of the element. J Biol Chem 265, 3757-3762.

Sandmeier, H., Iida, S., Meyer, J., Hiestand-Nauer, R. , and Arber, W. (1990): Site-specific DNA recombination system Min of plasmid p15B: a cluster of overlapping invertible DNA segments. Proc Natl Acad Sci U S A 87, 1109-1113.

Iida, S., Sandmeier, H., Hubner, P., Hiestand-Nauer, R., Schneitz, K. , and Arber, W. (1990): The Min DNA inversion enzyme of plasmid p15B of Escherichia coli 15T-: a new member of the Din family of site-specific recombinases. Mol Microbiol 4, 991-997.

Arber, W. (1990): Mechanisms in microbial evolution. J Struct Biol 104, 107-111.

Stalder, R. , and Arber, W. (1989): Characterization of in vitro constructed IS30-flanked transposons. Gene 76, 187-193.

Hubner, P., Haffter, P., Iida, S. , and Arber, W. (1989): Bent DNA is needed for recombinational enhancer activity in the site-specific recombination system Cin of bacteriophage P1. The role of FIS protein. J Mol Biol 205, 493-500.

Hubner, P. , and Arber, W. (1989): Mutational analysis of a prokaryotic recombinational enhancer element with two functions. Embo J 8, 577-585.

Guidolin, A., Zingg, J.M., Lehnherr, H. , and Arber, W. (1989): Bacteriophage P1 tail-fibre and dar operons are expressed from homologous phage-specific late promoter sequences. J Mol Biol 208, 615-622.

Guidolin, A., Zingg, J.M. , and Arber, W. (1989): Organization of the bacteriophage P1 tail-fibre operon. Gene 76, 239-243.

Hubner, P., Iida, S. , and Arber, W. (1988): Random mutagenesis using degenerate oligodeoxyribonucleotides. Gene 73, 319-325.

Sengstag, C. , and Arber, W. (1987): A cloned DNA fragment from bacteriophage P1 enhances IS2 insertion. Mol Gen Genet 206, 344-351.

Iida, S., Streiff, M.B., Bickle, T.A. , and Arber, W. (1987): Two DNA antirestriction systems of bacteriophage P1, darA, and darB: characterization of darA- phages. Virology 157, 156-166.

Iida, S., Kulka, I., Meyer, J. , and Arber, W. (1987): Amplification of drug resistance genes flanked by inversely repeated IS1 elements: involvement of IS1-promoted DNA rearrangements before amplification. J Bacteriol 169, 1447-1453.

Hubner, P., Iida, S. , and Arber, W. (1987): A transcriptional terminator sequence in the prokaryotic transposable element IS1. Mol Gen Genet 206, 485-490.

Sengstag, C., Iida, S., Hiestand-Nauer, R. , and Arber, W. (1986): Terminal inverted repeats of prokaryotic transposable element IS186 which can generate duplications of variable length at an identical target sequence. Gene 49, 153-156.

Meyer, J., Stalhammar-Carlemalm, M., Streiff, M., Iida, S. , and Arber, W. (1986): Sequence relations among the IncY plasmid p15B, P1, and P7 prophages. Plasmid 16, 81-89.

Iida, S., Hanni, C., Meyer, J. , and Arber, W. (1986): DNA inversion mediated by the r-determinant of plasmid NR1: evidence for the intramolecular replicative transposition of a 23 kb IS1-flanked transposon? Mol Gen Genet 205, 572-574.

Dalrymple, B. , and Arber, W. (1986): The characterization of terminators of RNA transcription on IS30 and an analysis of their role in IS element-mediated polarity. Gene 44, 1-10.

Mollet, B., Iida, S. , and Arber, W. (1985): Gene organization and target specificity of the prokaryotic mobile genetic element IS26. Mol Gen Genet 201, 198-203.

Mollet, B., Iida, S. , and Arber, W. (1985): An active variant of the prokaryotic transposable element IS903 carries an amber stop codon in the middle of an open reading frame. Mol Gen Genet 199, 534-536.

Iida, S., Meyer, J. , and Arber, W. (1985): Bacteriophage P1 derivatives unaffected in their growth by a large inversion or by IS insertions at various locations. J Gen Microbiol 131, 129-134.

Iida, S., Hiestand-Nauer, R., Meyer, J. , and Arber, W. (1985): Crossover sites cix for inversion of the invertible DNA segment C on the bacteriophage P7 genome. Virology 143, 347-351.

Iida, S., Hiestand-Nauer, R., Hanni, C. , and Arber, W. (1985): Reversion of a truncated gene for ampicillin resistance by genetic rearrangements in Escherichia coli K12. Mol Gen Genet 201, 174-177.

Iida, S., Hiestand-Nauer, R. , and Arber, W. (1985): Transposable element IS1 intrinsically generates target duplications of variable length. Proc Natl Acad Sci U S A 82, 839-843.

Dalrymple, B. , and Arber, W. (1985): Promotion of RNA transcription on the insertion element IS30 of E. coli K12. Embo J 4, 2687-2693.

Arber, W., Sengstag, C., Caspers, P. , and Dalrymple, B. (1985): Evolutionary relevance of genetic rearrangements involving plasmids. Basic Life Sci 30, 21-31.

Iida, S., Mollet, B., Meyer, J. , and Arber, W. (1984): Functional characterization of the prokaryotic mobile genetic element IS26. Mol Gen Genet 198, 84-89.

Iida, S., Huber, H., Hiestand-Nauer, R., Meyer, J., Bickle, T.A. , and Arber, W. (1984): The bacteriophage P1 site-specific recombinase cin: recombination events and DNA recognition sequences. Cold Spring Harb Symp Quant Biol 49, 769-777.

Dalrymple, B., Caspers, P. , and Arber, W. (1984): Nucleotide sequence of the prokaryotic mobile genetic element IS30. Embo J 3, 2145-2149.

Caspers, P., Dalrymple, B., Iida, S. , and Arber, W. (1984): IS30, a new insertion sequence of Escherichia coli K12. Mol Gen Genet 196, 68-73.

Sengstag, C., Shepherd, J.C. , and Arber, W. (1983): The sequence of the bacteriophage P1 genome region serving as hot target for IS2 insertion. Embo J 2, 1777-1781.

Sengstag, C. , and Arber, W. (1983): IS2 insertion is a major cause of spontaneous mutagenesis of the bacteriophage P1: non-random distribution of target sites. Embo J 2, 67-71.

Mollet, B., Iida, S., Shepherd, J. , and Arber, W. (1983): Nucleotide sequence of IS26, a new prokaryotic mobile genetic element. Nucleic Acids Res 11, 6319-6330.

Meyer, J., Iida, S. , and Arber, W. (1983): Physical analysis of the genomes of hybrid phages between phage P1 and plasmid p15B. J Mol Biol 165, 191-195.

Kennedy, K.E., Iida, S., Meyer, J., Stalhammar-Carlemalm, M., Hiestand-Nauer, R. , and Arber, W. (1983): Genome fusion mediated by the site specific DNA inversion system of bacteriophage P1. Mol Gen Genet 189, 413-421.

Iida, S., Meyer, J., Bachi, B., Stalhammar-Carlemalm, M., Schrickel, S., Bickle, T.A. , and Arber, W. (1983): DNA restriction--modification genes of phage P1 and plasmid p15B. Structure and in vitro transcription. J Mol Biol 165, 1-18.

Arber, W. (1983): Bacterial "inserted sequence" elements and their influence on genetic stability and evolution. Prog Nucleic Acid Res Mol Biol 29, 27-33.

Iida, S., Meyer, J., Linder, P., Goto, N., Nakaya, R., Reif, H.J. , and Arber, W. (1982): The kanamycin resistance transposon Tn2680 derived from the R plasmid Rts1 and carried by phage P1Km has flanking 0.8-kb-long direct repeats. Plasmid 8, 187-198.

Iida, S., Meyer, J., Kennedy, K.E. , and Arber, W. (1982): A site-specific, conservative recombination system carried by bacteriophage P1. Mapping the recombinase gene cin and the cross-over sites cix for the inversion of the C segment. Embo J 1, 1445-1453.

Hanni, C., Meyer, J., Iida, S. , and Arber, W. (1982): Occurrence and properties of composite transposon Tn2672: evolution of multiple drug resistance transposons. J Bacteriol 150, 1266-1273.

Iida, S., Meyer, J. , and Arber, W. (1981): Cointegrates between bacteriophage P1 DNA and plasmid pBR322 derivatives suggest molecular mechanisms for P1-mediated transduction of small plasmids. Mol Gen Genet 184, 1-10.

Iida, S., Meyer, J. , and Arber, W. (1981): Genesis and natural history of IS-mediated transposons. Cold Spring Harb Symp Quant Biol 45, 27-43.

Iida, S., Hanni, C., Echarti, C. , and Arber, W. (1981): Is the IS1-flanked r-determinant of the R plasmid NR1 a transposon? J Gen Microbiol 126, 413-425.

Meyer, J., Iida, S. , and Arber, W. (1980): Does the insertion element IS1 transpose preferentially into A+T-rich DNA segments? Mol Gen Genet 178, 471-473.

Iida, S. , and Arber, W. (1980): On the role of IS1 in the formation of hybrids between the bacteriophage P1 and the R plasmid NR1. Mol Gen Genet 177, 261-270.

Arber, W. (1980): [Not all risks of medical progress and biological basic research are predictable]. Bull Schweiz Akad Med Wiss 36, 389-393.

Iida, S. , and Arber, W. (1979): Multiple physical differences in the genome structure of functionally related bacteriophages P1 and P7. Mol Gen Genet 173, 249-261.

Arber, W., Iida, S., Jutte, H., Caspers, P., Meyer, J. , and Hanni, C. (1979): Rearrangements of genetic material in Escherichia coli as observed on the bacteriophage P1 plasmid. Cold Spring Harb Symp Quant Biol 43, 1197-1208.

Arber, W. (1979): Promotion and limitation of genetic exchange. Science 205, 361-365.

Arber, W. (1979): Promotion and limitation of genetic exchange. Experientia 35, 287-293.

Iida, S., Meyer, J. , and Arber, W. (1978): The insertion element IS1 is a natural constituent of coliphage P1 DNA. Plasmid 1, 357-365.

Elliott, J. , and Arber, W. (1978): E. coli K-12 pel mutants, which block phage lambda DNA injection, coincide with ptsM, which determines a component of a sugar transport system. Mol Gen Genet 161, 1-8.

Arber, W. (1978): Restriction endonucleases. Angew Chem Int Ed Engl 17, 73-79.

Iida, S. , and Arber, W. (1977): Plaque forming specialized transducing phage P1: isolation of P1CmSmSu, a precursor of P1Cm. Mol Gen Genet 153, 259-269.

Gschwind, N. , and Arber, W. (1977): Normal expression of the viral gene N interferes with growth of bacteriophage lambda in Escherichia coli 15T. Mol Gen Genet 155, 19-26.

Bachi, B. , and Arber, W. (1977): Physical mapping of BglII, BamHI, EcoRI, HindIII and PstI restriction fragments of bacteriophage P1 DNA. Mol Gen Genet 153, 311-324.

Scandella, D. , and Arber, W. (1976): Phage lambda DNA injection into Escherichia coli pel- mutants is restored by mutations in phage genes V or H. Virology 69, 206-215.

Mise, K. , and Arber, W. (1976): Plaque-forming transducing bacteriophage P1 derivatives and their behaviour in lysogenic conditions. Virology 69, 191-205.

Scandella, D. , and Arber, W. (1974): An Escherichia coli mutant which inhibits the injection of phage lambda DNA. Virology 58, 504-513.

Arber, W. (1974): DNA modification and restriction. Prog Nucleic Acid Res Mol Biol 14, 1-37.

Smith, J.D., Arber, W. , and Kuhnlein, U. (1972): Host specificity of DNA produced by Escherichia coli. XIV. The role of nucleotide methylation in in vivo B-specific modification. J Mol Biol 63, 1-8.

Kuhnlein, U. , and Arber, W. (1972): Host specificity of DNA produced by Escherichia coli. XV. The role of nucleotide methylation in in vitro B-specific modification. J Mol Biol 63, 9-19.

Arber, W., Rifat, A., Wauters-Willems, D. , and Kuhnlein, U. (1972): Host specificity of DNA produced by Escherichia coli. XVI. Phage lambda DNA carries a single site of affinity for A-specific restriction and modification. Mol Gen Genet 115, 195-207.

Lark, C. , and Arber, W. (1970): Host specificity of DNA produced by Escherichia coli. 13. Breakdown of cellular DNA upon growth in ethionine of strains with r plus-15, r plus-P1 or r plus-N3 restriction phenotypes. J Mol Biol 52, 337-348.

Arber, W. , and Wauters-Willems, D. (1970): Host specificity of DNA produced by Escherichia coli. XII. The two restriction and modification systems of strain 15T. Mol Gen Genet 108, 203-217.

Mechler, B. , and Arber, W. (1969): Parental fd DNA is efficiently transferred into progeny bacteriophage particles even at low multiplicity of infection. J Mol Biol 45, 443-449.

Kuhnlein, U., Linn, S. , and Arber, W. (1969): [In vitro modification of the replicative form of fd bacteriophage]. Pathol Microbiol 34, 136.

Kuhnlein, U., Linn, S. , and Arber, W. (1969): Host specificity of DNA produced by Escherichia coli. XI. In vitro modification of phage fd replicative form. Proc Natl Acad Sci U S A 63, 556-562.

Bickle, T. , and Arber, W. (1969): Host-controlled restriction and modification of filamentous 1- and F-specific bacteriophages. Virology 39, 605-607.

Arber, W. , and Linn, S. (1969): DNA modification and restriction. Annu Rev Biochem 38, 467-500.

Arber, W. (1969): [Origin and properties of type A host specificity in Escherichia coli]. Pathol Microbiol 34, 147.

Linn, S. , and Arber, W. (1968): Host specificity of DNA produced by Escherichia coli, X. In vitro restriction of phage fd replicative form. Proc Natl Acad Sci U S A 59, 1300-1306.

Arber, W. , and Kuhnlein, U. (1967): [Mutational loss of the B-specific restriction in bacteriophage fd]. Pathol Microbiol 30, 946-952.

Arber, W. (1967): [Factors of antibiotic resistance. Viewpoint of the molecular geneticist]. Pathol Microbiol 30, 1007-1014.

Kellenberger, G., Symonds, N. , and Arber, W. (1966): Host specificity of DNA produced by Escherichia coli. 8. Its acquisition by phage lambda and its persistence through consecutive growth cycles. Z Vererbungsl 98, 247-256.

Arber, W. (1966): Host specificity of DNA produced by Escherichia coli. 9. Host-controlled modification of bacteriophage fd. J Mol Biol 20, 483-496.

Arber, W. (1965): Host-controlled modification of bacteriophage. Annu Rev Microbiol 19, 365-378.

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