Prof. Dr. Thomas Mrsic-Flogel

University of Basel
Klingelbergstrasse 50 / 70
CH - 4056 Basel
Biozentrum, Room 605.1 Phone: +41 61 207 17 66
Curriculum Vitae

Administrative Assistant

Susanna Notz
Biozentrum, Room 608
Phone: +41 61 207 21 91
Fax: +41 61 207 21 89

Research Group Thomas Mrsic-Flogel


Poort, Jasper; Khan, Adil G; Pachitariu, Marius; Nemri, Abdellatif; Orsolic, Ivana; Krupic, Julija; Bauza, Marius; Sahani, Maneesh; Keller, Georg B; Mrsic-Flogel, Thomas D; Hofer, Sonja B (2015). Learning Enhances Sensory and Multiple Non-sensory Representations in Primary Visual Cortex. Neuron, 86(6), 1478-90.
Muir, Dylan R; Mrsic-Flogel, Thomas (2015). Eigenspectrum bounds for semirandom matrices with modular and spatial structure for neural networks. Physical review. E, Statistical, nonlinear, and soft matter physics, 91(4), 042808.
Okun, Michael; Steinmetz, Nicholas A; Cossell, Lee; Iacaruso, M Florencia; Ko, Ho; Barthó, Péter; Moore, Tirin; Hofer, Sonja B; Mrsic-Flogel, Thomas D; Carandini, Matteo; Harris, Kenneth D (2015). Diverse coupling of neurons to populations in sensory cortex. Nature, 521(7553), 511-5.
Cossell, Lee; Iacaruso, Maria Florencia; Muir, Dylan R; Houlton, Rachael; Sader, Elie N; Ko, Ho; Hofer, Sonja B; Mrsic-Flogel, Thomas D (2015). Functional organization of excitatory synaptic strength in primary visual cortex. Nature, 518(7539), 399-403.
Pecka, Michael; Han, Yunyun; Sader, Elie; Mrsic-Flogel, Thomas D (2014). Experience-dependent specialization of receptive field surround for selective coding of natural scenes. Neuron, 84(2), 457-69.
Ko, Ho; Mrsic-Flogel, Thomas D; Hofer, Sonja B (2014). Emergence of feature-specific connectivity in cortical microcircuits in the absence of visual experience. Journal of neuroscience, 34(29), 9812-6.
Harris, Kenneth D; Mrsic-Flogel, Thomas D (2013). Cortical connectivity and sensory coding. Nature, 503(7474), 51-8.
Ko, Ho; Cossell, Lee; Baragli, Chiara; Antolik, Jan; Clopath, Claudia; Hofer, Sonja B; Mrsic-Flogel, Thomas D (2013). The emergence of functional microcircuits in visual cortex. Nature, 496(7443), 96-100.
Mrsic-Flogel, Thomas D; Bonhoeffer, Tobias (2012). Neuroscience: Sibling neurons bond to share sensations. Nature, 486(7401), 41-2.
Hofer, Sonja B; Ko, Ho; Pichler, Bruno; Vogelstein, Joshua; Ros, Hana; Zeng, Hongkui; Lein, Ed; Lesica, Nicholas A; Mrsic-Flogel, Thomas D (2011). Differential connectivity and response dynamics of excitatory and inhibitory neurons in visual cortex. Nature Neuroscience, 14(8), 1045-52.
Ko, Ho; Hofer, Sonja B; Pichler, Bruno; Buchanan, Katherine A; Sjöström, P Jesper; Mrsic-Flogel, Thomas D (2011). Functional specificity of local synaptic connections in neocortical networks. Nature, 473(7345), 87-91.
Hofer, Sonja B; Mrsic-Flogel, Thomas D; Horvath, Domonkos; Grothe, Benedikt; Lesica, Nicholas A (2010). Optimization of population decoding with distance metrics. Neural Networks, 23(6), 728-32.
Holtmaat, Anthony; Bonhoeffer, Tobias; Chow, David K; Chuckowree, Jyoti; De Paola, Vincenzo; Hofer, Sonja B; Hübener, Mark; Keck, Tara; Knott, Graham; Lee, Wei-Chung A; Mostany, Ricardo; Mrsic-Flogel, Tom D; Nedivi, Elly; Portera-Cailliau, Carlos; Svoboda, Karel; Trachtenberg, Joshua T; Wilbrecht, Linda (2009). Long-term, high-resolution imaging in the mouse neocortex through a chronic cranial window. Nature Protocols, 4(8), 1128-44.
Hofer, Sonja B; Mrsic-Flogel, Thomas D; Bonhoeffer, Tobias; Hübener, Mark (2009). Experience leaves a lasting structural trace in cortical circuits. Nature, 457(7227), 313-7.
Mank, Marco; Santos, Alexandre Ferrão; Direnberger, Stephan; Mrsic-Flogel, Thomas D; Hofer, Sonja B; Stein, Valentin; Hendel, Thomas; Reiff, Dierk F; Levelt, Christiaan; Borst, Alexander; Bonhoeffer, Tobias; Hübener, Mark; Griesbeck, Oliver (2008). A genetically encoded calcium indicator for chronic in vivo two-photon imaging. Nature Methods, 5(9), 805-11.
Keck, Tara; Mrsic-Flogel, Thomas D; Vaz Afonso, Miguel; Eysel, Ulf T; Bonhoeffer, Tobias; Hübener, Mark (2008). Massive restructuring of neuronal circuits during functional reorganization of adult visual cortex. Nature Neuroscience, 11(10), 1162-7.
Chakravarthy, Sridhara; Keck, Tara; Roelandse, Martijn; Hartman, Robin; Jeromin, Andreas; Perry, Sean; Hofer, Sonja B; Mrsic-Flogel, Thomas; Levelt, Christiaan N (2008). Cre-dependent expression of multiple transgenes in isolated neurons of the adult forebrain. PloS one, 3(8), e3059.
Hübener, Mark; Hofer, Sonja B; Mrsic-Flogel, Thomas D; : Ocular dominance plasticity, in: Chalupa, LM; Williams, RW (Ed.). (2008). Eye, Retina, and Visual System of the Mouse, Cambridge, MA: MIT Press , S. 439-448.
Mrsic-Flogel, Thomas D; Hofer, Sonja B; Ohki, Kenichi; Reid, R Clay; Bonhoeffer, Tobias; Hübener, Mark (2007). Homeostatic regulation of eye-specific responses in visual cortex during ocular dominance plasticity. Neuron, 54(6), 961-72.
Hofer, Sonja B; Mrsic-Flogel, Thomas D; Bonhoeffer, Tobias; Hübener, Mark (2006). Lifelong learning: ocular dominance plasticity in mouse visual cortex. Current Opinion in Neurobiology, 16(4), 451-9.
Mrsic-Flogel, Thomas D; Versnel, Huib; King, Andrew J (2006). Development of contralateral and ipsilateral frequency representations in ferret primary auditory cortex. The European Journal of Neuroscience, 23(3), 780-92.
Hofer, Sonja B; Mrsic-Flogel, Thomas D; Bonhoeffer, Tobias; Hübener, Mark (2006). Prior experience enhances plasticity in adult visual cortex. Nature Neuroscience, 9(1), 127-32.
Nelken, Israel; Chechik, Gal; Mrsic-Flogel, Thomas D; King, Andrew J; Schnupp, Jan W H (2005). Encoding stimulus information by spike numbers and mean response time in primary auditory cortex. Journal of Computational Neuroscience, 19(2), 199-221.
Egea, Joaquim; Nissen, Ulla Vig; Dufour, Audrey; Sahin, Mustafa; Greer, Paul; Kullander, Klas; Mrsic-Flogel, Thomas D; Greenberg, Michael E; Kiehn, Ole; Vanderhaeghen, Pierre; Klein, Rüdiger (2005). Regulation of EphA 4 kinase activity is required for a subset of axon guidance decisions suggesting a key role for receptor clustering in Eph function. Neuron, 47(4), 515-28.
Mrsic-Flogel, Thomas D; Hofer, Sonja B; Creutzfeldt, Claire; Cloëz-Tayarani, Isabelle; Changeux, Jean-Pierre; Bonhoeffer, Tobias; Hübener, Mark (2005). Altered map of visual space in the superior colliculus of mice lacking early retinal waves. The Journal of Neuroscience, 25(29), 6921-8.
Mrsic-Flogel, Thomas D; King, Andrew J; Schnupp, Jan W H (2005). Encoding of virtual acoustic space stimuli by neurons in ferret primary auditory cortex. Journal of Neurophysiology, 93(6), 3489-503.
Mrsic-Flogel, Thomas D; Schnupp, Jan W H; King, Andrew J (2003). Acoustic factors govern developmental sharpening of spatial tuning in the auditory cortex. Nature Neuroscience, 6(9), 981-8.
Mrsic-Flogel, Thomas D; Hübener, Mark; Bonhoeffer, Tobias (2003). Brain mapping: New wave optical imaging. Current Biology, 13, R778-R780.
Versnel, Huib; Mossop, Jennifer E; Mrsic-Flogel, Thomas D; Ahmed, Bashir; Moore, David R (2002). Optical imaging of intrinsic signals in ferret auditory cortex: responses to narrowband sound stimuli. Journal of Neurophysiology, 88(3), 1545-58.
Mrsic-Flogel, Thomas D; Hübener, Mark (2002). Visual cortex: Supression by depression. Current Biology, 12, R547-R549.
Schnupp, J W; Mrsic-Flogel, T D; King, A J (2001). Linear processing of spatial cues in primary auditory cortex. Nature, 414(6860), 200-4.
King, A J; Kacelnik, O; Mrsic-Flogel, T D; Schnupp, J W; Parsons, C H; Moore, D R (2001). How plastic is spatial hearing?. Audiology & Neuro-Otology, 6(4), 182-6.
Mrsic-Flogel, T D; King, A J; Jenison, R L; Schnupp, J W (2001). Listening through different ears alters spatial response fields in ferret primary auditory cortex. Journal of Neurophysiology, 86(2), 1043-6.
Ledig, M M; McKinnell, I W; Mrsic-Flogel, T; Wang, J; Alvares, C; Mason, I; Bixby, J L; Mueller, B K; Stoker, A W (1999). Expression of receptor tyrosine phosphatases during development of the retinotectal projection of the chick. Journal of Neurobiology, 39(1), 81-96.

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