Prof. Dr. Henning Stahlberg

Biozentrum
University of Basel
at the Department for Biosystems Science and Engineering (D-BSSE)
Mattenstrasse 26
CH - 4058 Basel
WRO-1058 , Room P16 Phone: +41 61 387 32 62
Email: henning.stahlberg-at-unibas.ch
Curriculum Vitae

Contact: Karen Bergmann
WRO-1058 , Room P18
Phone: +41 61 387 32 31
Email: karen.bergmann-at-unibas.ch

Research group Henning Stahlberg

2012
Kudryashev, M.; Stahlberg, H.; Castano-Diez, D. (2012). Assessing the benefits of focal pair cryo-electron tomography. J. Struct. Biol., (in press), TBD.
Arheit, M.; Castano-Diez, D.; Thierry, R.; Gipson, B.; Zeng, X.; Stahlberg, H. (2012). Automation of Image Processign in Electron Crystallography. Methods in Molecular Biology, in press, TBD.
Arheit, M.; Castano-Diez, D.; Thierry, R.; Gipson, B. R.; Zeng, X.; Stahlberg, H. (2012). Image Processing for 2D Crystal Images. Methods in Molecular Biology, in press, TBD.
Arheit, M.; Castano-Diez, D.; Thierry, R.; Abeyrathne, P. D.; Gipson, B. R.; Stahlberg, H. (2012). Merging of Image Data in Electron Crystallography. Methods in Molecular Biology, in press, TBD.
Abeyrathne, P. D.; Arheit, M.; Kebbel, F.; Castano-Diez, D.; Goldie, K. N.; Chami, M.; Renault, L.; Kühlbrandt, W.; Stahlberg, H. (2012). Electron Microscopy Analysis of 2D Crystals of Membrane Proteins. Comprehensive Biophysics, 1.19(in press), TBD.
Kemmerling, Simon; Ziegler, Jörg; Schweighauser, Gabriel; Arnold, Stefan; Giss, Dominic; Müller, Shirley A.; Ringler, Philippe; Goldie, Kenneth N.; Goedecke, Niels; Hierlemann, Andreas; Stahlberg, Henning; Engel, Andreas; Braun, Thomas (2012). Connecting micro-fluidics to Electron Microscopy. J. Struct. Biol., (in press), TBD.
2011
Castano-Diez, D.; Kudryashev, M.; Arheit, M.; Stahlberg, H. (2011). Dynamo: A flexible, user-friendly development tool for subtomogram averaging of cryo-EM data in High Performance Computing environments. J. Struct. Biol., {in press}, TBD.
Gipson, B. R.; Masiel, D. J.; Browning, N. D.; Spence, J.; Mitsuoka, K.; Stahlberg, H. (2011). Automatic recovery of missing amplitudes and phases in tilt-limited electron crystallography of two-dimensional crystals. Phys Rev E Stat Nonlin Soft Matter Phys, 84(1 Pt 1), 011916.
Liu, J.; Renault, L.; Veaute, X.; Fabre, F.; Stahlberg, H.; Heyer, W. D. (2011). Rad51 paralogs Rad55-Rad57 balance the anti-recombinase Srs2 in Rad51 pre-synaptic filament formation. Nature, 479(7372), 245-248.
Dudkina, N. V.; Kudryashev, M.; Stahlberg, H.; Boekema, E. J. (2011). Interaction of complexes I, III, and IV within the bovine respirasome by single particle cryoelectron tomography. Proc Natl Acad Sci U S A, 108(37), 15196-200.
Klammt, C.; Perrin, M. H.; Maslennikov, I.; Renault, L.; Krupa, M.; Kwiatkowski, W.; Stahlberg, H.; Vale, W.; Choe, S. (2011). Polymer-based cell-free expression of ligand-binding family B G-protein coupled receptors without detergents. Protein Sci, 20(6), 1030-41.
Pantelic, R. S.; Suk, J. W.; Hao, Y.; Ruoff, R. S.; Stahlberg, H. (2011). Oxidative Doping Renders Graphene Hydrophilic, Facilitating Its Use As a Support in Biological TEM. Nano Lett, 11(10), 4319-23.
Pantelic, R. S.; Suk, J. W.; Magnuson, C. W.; Meyer, J. C.; Wachsmuth, P.; Kaiser, U.; Ruoff, R. S.; Stahlberg, H. (2011). Graphene: Substrate preparation and introduction. J Struct Biol, 174(1), 234-8.
2010
Schenk, Andreas D; Castaño-Díez, Daniel; Gipson, Bryant; Arheit, Marcel; Zeng, Xiangyan; Stahlberg, Henning (2010). 3D reconstruction from 2D crystal image and diffraction data. Methods in enzymology, 482, 101-29.
Abeyrathne, Priyanka D; Chami, Mohamed; Pantelic, Radosav S; Goldie, Kenneth N; Stahlberg, Henning (2010). Preparation of 2D crystals of membrane proteins for high-resolution electron crystallography data collection. Methods in enzymology, 481, 25-43.
Paoli, E E; Kruse, D E; Seo, J W; Zhang, H; Kheirolomoom, A; Watson, K D; Chiu, P; Stahlberg, H; Ferrara, K W (2010). An optical and microPET assessment of thermally-sensitive liposome biodistribution in the Met-1 tumor model: Importance of formulation. Journal of controlled release : official journal of the Controlled Release Society, 143(1), 13-22.
Buban, James P; Ramasse, Quentin; Gipson, Bryant; Browning, Nigel D; Stahlberg, Henning (2010). High-resolution low-dose scanning transmission electron microscopy. Journal of electron microscopy, 59(2), 103-12.
2009
Buban, J. P.; Chi, M.; Masiel, D.J.; Bradley, A.; Jiang, B.; Stahlberg, H.; Browning, N.D. (2009). Structural variability of edge dislocations in a SrTiO3 low-angle [001] tilt grain boundary. J. of Materials Research, 24(7), 2191-2199.
DeVay, Rachel M; Dominguez-Ramirez, Lenin; Lackner, Laura L; Hoppins, Suzanne; Stahlberg, Henning; Nunnari, Jodi (2009). Coassembly of Mgm1 isoforms requires cardiolipin and mediates mitochondrial inner membrane fusion. The Journal of cell biology, 186(6), 793-803.
Shrive, Annette K; Burns, Ian; Chou, Hui-Ting; Stahlberg, Henning; Armstrong, Peter B; Greenhough, Trevor J (2009). Crystal structures of Limulus SAP-like pentraxin reveal two molecular aggregations. Journal of molecular biology, 386(5), 1240-54.
Harrington, John M; Chou, Hui-Ting; Gutsmann, Thomas; Gelhaus, Christoph; Stahlberg, Henning; Leippe, Matthias; Armstrong, Peter B (2009). Membrane activity of a C-reactive protein. FEBS letters, 583(6), 1001-5.
Stroud, Robert M; Choe, Senyon; Holton, James; Kaback, H Ronald; Kwiatkowski, Witek; Minor, Daniel L; Riek, Roland; Sali, Andrej; Stahlberg, Henning; Harries, William (2009). 2007 annual progress report synopsis of the Center for Structures of Membrane Proteins. Journal of structural and functional genomics, 10(2), 193-208.
2008
Gipson, B.; Zeng, X.; Stahlberg, H. (2008). 2dx - Automated 3D structure reconstruction from 2D crystal data. Microscopy and Microanalysis, 14(Suppl. 2), 1290-1291.
Evans, James E; Hetherington, Crispin; Kirkland, Angus; Chang, Lan-Yun; Stahlberg, Henning; Browning, Nigel (2008). Low-dose aberration corrected cryo-electron microscopy of organic specimens. Ultramicroscopy, 108(12), 1636-44.
Vinchurkar, Madhuri S; Bricarello, Daniel A; Lagerstedt, Jens O; Buban, James P; Stahlberg, Henning; Oda, Michael N; Voss, John C; Parikh, Atul N (2008). Bridging across length scales: multi-scale ordering of supported lipid bilayers via lipoprotein self-assembly and surface patterning. Journal of the American Chemical Society, 130(33), 11164-9.
Vilar, Marçal; Chou, Hui-Ting; Lührs, Thorsten; Maji, Samir K; Riek-Loher, Dominique; Verel, Rene; Manning, Gerard; Stahlberg, Henning; Riek, Roland (2008). The fold of alpha-synuclein fibrils. Proceedings of the National Academy of Sciences of the United States of America, 105(25), 8637-42.
Stahlberg, Henning; Walz, Thomas (2008). Molecular electron microscopy: state of the art and current challenges. ACS chemical biology, 3(5), 268-81.
Harrington, John M; Chou, Hui-Ting; Gutsmann, Thomas; Gelhaus, Christoph; Stahlberg, Henning; Leippe, Matthias; Armstrong, Peter B (2008). Membrane pore formation by pentraxin proteins from Limulus, the American horseshoe crab. The Biochemical journal, 413(2), 305-13.
2007
Renault, L.; Stahlberg, H. (2007). Three-dimensional electron microscopy of macromolecular assemblies (J. Frank). Book Review. Scanning, 29(1), 37.
Hankamer, Ben; Glaeser, Robert; Stahlberg, Henning: Electron crystallography of membrane proteins, in: Journal of structural biology 160, 2007, H. 3, S. 263-4.
Gipson, Bryant; Zeng, Xiangyan; Stahlberg, Henning (2007). 2dx_merge: data management and merging for 2D crystal images. Journal of structural biology, 160(3), 375-84.
Zeng, Xiangyan; Stahlberg, Henning; Grigorieff, Nikolaus (2007). A maximum likelihood approach to two-dimensional crystals. Journal of structural biology, 160(3), 362-74.
Zeng, Xiangyan; Gipson, Bryant; Zheng, Zi Yan; Renault, Ludovic; Stahlberg, Henning (2007). Automatic lattice determination for two-dimensional crystal images. Journal of structural biology, 160(3), 353-61.
Chiu, Po-Lin; Pagel, Matthew D; Evans, James; Chou, Hui-Ting; Zeng, Xiangyan; Gipson, Bryant; Stahlberg, Henning; Nimigean, Crina M (2007). The structure of the prokaryotic cyclic nucleotide-modulated potassium channel MloK1 at 16 A resolution. Structure (London, England : 1993), 15(9), 1053-64.
Runge, Kathryn E; Evans, James E; He, Zhi-Yong; Gupta, Surabhi; McDonald, Kent L; Stahlberg, Henning; Primakoff, Paul; Myles, Diana G (2007). Oocyte CD9 is enriched on the microvillar membrane and required for normal microvillar shape and distribution. Developmental biology, 304(1), 317-25.
Di Luccio, Eric; Petschacher, Barbara; Voegtli, Jennifer; Chou, Hui-Ting; Stahlberg, Henning; Nidetzky, Bernd; Wilson, David K (2007). Structural and kinetic studies of induced fit in xylulose kinase from Escherichia coli. Journal of molecular biology, 365(3), 783-98.
Gipson, Bryant; Zeng, Xiangyan; Zhang, Zi Yan; Stahlberg, Henning (2007). 2dx--user-friendly image processing for 2D crystals. Journal of structural biology, 157(1), 64-72.
2006
Nicotra, G.; Chou, H. T.; Stahlberg, H.; Browing, N. D. (2006). Avoiding charge induced drift in vitrified biological specimens through scanning transmission electron microscopy. Microscopy and Microanalysis, 12(Supp. S02), 246-247.
Chou, H. T.; Di Luccio, E.; Wilson, D. K.; Stahlberg, H. (2006). Cryo-Electron Microscopy Analysis of a 105 kDa Protein Particle: The Xylose Kinase from E. coli. Microscopy and Microanalysis, 12(Supp. S02), 408-409.
Muller, S.A.; Pozidis, C.; Stone, R.; Meesters, C.; Chami, M.; Engel, A.; Economou, A.; Stahlberg, H. (2006). Double hexameric ring assembly of the type III protein translocase ATPase HrcN. Molecular Microbiology, 61(1), 119-125.
Tao, Li; Mogilner, Alex; Civelekoglu-Scholey, Gul; Wollman, Roy; Evans, James; Stahlberg, Henning; Scholey, Jonathan M (2006). A homotetrameric kinesin-5, KLP61F, bundles microtubules and antagonizes Ncd in motility assays. Current biology : CB, 16(23), 2293-302.
Renault, Ludovic; Chou, Hui-Ting; Chiu, Po-Lin; Hill, Rena M; Zeng, Xiangyan; Gipson, Bryant; Zhang, Zi Yan; Cheng, Anchi; Unger, Vinzenz; Stahlberg, Henning (2006). Milestones in electron crystallography. Journal of computer-aided molecular design, 20(7-8), 519-27.
Evans, James E; Snow, Joshua J; Gunnarson, Amy L; Ou, Guangshuo; Stahlberg, Henning; McDonald, Kent L; Scholey, Jonathan M (2006). Functional modulation of IFT kinesins extends the sensory repertoire of ciliated neurons in Caenorhabditis elegans. The Journal of cell biology, 172(5), 663-9.
2005
Schenk, Andreas D; Werten, Paul J L; Scheuring, Simon; de Groot, Bert L; Müller, Shirley A; Stahlberg, Henning; Philippsen, Ansgar; Engel, Andreas (2005). The 4.5 A structure of human AQP2. Journal of molecular biology, 350(2), 278-89.
2004
Stahlberg, H; Kutejová, E; Muchová, K; Gregorini, M; Lustig, A; Müller, S A; Olivieri, V; Engel, A; Wilkinson, A J; Barák, I (2004). Oligomeric structure of the Bacillus subtilis cell division protein DivIVA determined by transmission electron microscopy. Molecular microbiology, 52(5), 1281-90.
2003
Philippsen, A.; Schenk, A.D.; Stahlberg, H.; Engel, A. (2003). Iplt--image processing library and toolkit for the electron microscopy community. Journal of Structural Biology, 144(1-2), 4-12.
Pozidis, Charalambos; Chalkiadaki, Aggeliki; Gomez-Serrano, Amalia; Stahlberg, Henning; Brown, Ian; Tampakaki, Anastasia P; Lustig, Ariel; Sianidis, Giorgos; Politou, Anastasia S; Engel, Andreas; Panopoulos, Nickolas J; Mansfield, John; Pugsley, Anthony P; Karamanou, Spyridoula; Economou, Anastassios (2003). Type III protein translocase: HrcN is a peripheral ATPase that is activated by oligomerization. The Journal of biological chemistry, 278(28), 25816-24.
2002
Stahlberg, H.; Heymann, B.; Mitsuoka, K.; Fushyihoshi, Y.; Engel, A.: The aquaporin superfamily: structure and function, in: Hohmann, S.; Agre, P.; Nielsen, S. (Ed.). (2002). Current Topics in Membranes, New York: Academic Press , S. 39-119.
Stahlberg, H.; Engel, A.; Philippsen, A. (2002). Assessing the structure of membrane proteins: combining different methods gives the full picture. Biochemistry and Cell Biology = Biochimie et Biologie Cellulaire, 80(5), 563-568.
Werten, P J L; Rémigy, H W; de Groot, B L; Fotiadis, D; Philippsen, A; Stahlberg, H; Grubmüller, H; Engel, A (2002). Progress in the analysis of membrane protein structure and function. FEBS letters, 529(1), 65-72.
Scheuring, Simon; Müller, Daniel J; Stahlberg, Henning; Engel, Hans-Andreas; Engel, Andreas (2002). Sampling the conformational space of membrane protein surfaces with the AFM. European biophysics journal : EBJ, 31(3), 172-8.
Scheuring, Simon; Stahlberg, Henning; Chami, Mohamed; Houssin, Christine; Rigaud, Jean-Louis; Engel, Andreas (2002). Charting and unzipping the surface layer of Corynebacterium glutamicum with the atomic force microscope. Molecular microbiology, 44(3), 675-84.
Engel, Andreas; Stahlberg, Henning (2002). Aquaglyceroporins: channel proteins with a conserved core, multiple functions, and variable surfaces. International review of cytology, 215, 75-104.
2001
Müller, D J; Dencher, N A; Meier, T; Dimroth, P; Suda, K; Stahlberg, H; Engel, A; Seelert, H; Matthey, U (2001). ATP synthase: constrained stoichiometry of the transmembrane rotor. FEBS letters, 504(3), 219-22.
Stahlberg, H; Fotiadis, D; Scheuring, S; Rémigy, H; Braun, T; Mitsuoka, K; Fujiyoshi, Y; Engel, A (2001). Two-dimensional crystals: a powerful approach to assess structure, function and dynamics of membrane proteins. FEBS letters, 504(3), 166-72.
Stahlberg, H; Müller, D J; Suda, K; Fotiadis, D; Engel, A; Meier, T; Matthey, U; Dimroth, P (2001). Bacterial Na(+)-ATP synthase has an undecameric rotor. EMBO reports, 2(3), 229-33.
2000
Braun, T; Philippsen, A; Wirtz, S; Borgnia, M J; Agre, P; Kühlbrandt, W; Engel, A; Stahlberg, H (2000). The 3.7 A projection map of the glycerol facilitator GlpF: a variant of the aquaporin tetramer. EMBO reports, 1(2), 183-9.
Stahlberg, H; Braun, T; de Groot, B; Philippsen, A; Borgnia, M J; Agre, P; Kühlbrandt, W; Engel, A (2000). The 6.9-A structure of GlpF: a basis for homology modeling of the glycerol channel from Escherichia coli. Journal of structural biology, 132(2), 133-41.
Fotiadis, D; Hasler, L; Müller, D J; Stahlberg, H; Kistler, J; Engel, A (2000). Surface tongue-and-groove contours on lens MIP facilitate cell-to-cell adherence. Journal of molecular biology, 300(4), 779-89.
Scheuring, S; Tittmann, P; Stahlberg, H; Ringler, P; Borgnia, M; Agre, P; Gross, H; Engel, A (2000). The aquaporin sidedness revisited. Journal of molecular biology, 299(5), 1271-8.
Seelert, H; Poetsch, A; Dencher, N A; Engel, A; Stahlberg, H; Müller, D J (2000). Structural biology. Proton-powered turbine of a plant motor. Nature, 405(6785), 418-9.
Braun, T.; Philippsen, A.; Wirtz, S.; Borgnia, M.; Agre, P.; Kühlbrandt, W.; Engel, A; Stahlberg, H: GlpF: A structural variant of the aquaporin tetramer, in: Hohmann, S.; Nielsen, S. (Ed.). (2000). Molecular biology and physiology of water and solute transport, New York: Kluwer Academic , S. 13-22.
Nouwen, N.; Stahlberg, H.; Pugsley, A. P.; Engel, A. (2000). Domain structure of secretin PulD revealed by limited proteolysis and electron microscopy. Embo J, 19(10), 2229-36..
1999
Dubochet, J.; Stahlberg, H.: Cryo electron microscopy, in: M. R. Ltd. (Ed.). (1999). Encyclopedia of life Sciences, London: Wiley , S. 1-5.
Ringler, P; Borgnia, M J; Stahlberg, H; Maloney, P C; Agre, P; Engel, A (1999). Structure of the water channel AqpZ from Escherichia coli revealed by electron crystallography. Journal of molecular biology, 291(5), 1181-90.
Scheuring, S; Ringler, P; Borgnia, M; Stahlberg, H; Müller, D J; Agre, P; Engel, A (1999). High resolution AFM topographs of the Escherichia coli water channel aquaporin Z. The EMBO journal, 18(18), 4981-7.
Rémigy, H W; Stahlberg, H; Fotiadis, D; Müller, S A; Wolpensinger, B; Engel, A; Hauska, G; Tsiotis, G (1999). The reaction center complex from the green sulfur bacterium Chlorobium tepidum: a structural analysis by scanning transmission electron microscopy. Journal of molecular biology, 290(4), 851-8.
Stahlberg, H; Kutejová, E; Suda, K; Wolpensinger, B; Lustig, A; Schatz, G; Engel, A; Suzuki, C K (1999). Mitochondrial Lon of Saccharomyces cerevisiae is a ring-shaped protease with seven flexible subunits. Proceedings of the National Academy of Sciences of the United States of America, 96(12), 6787-90.
1998
Stahlberg, H.; Dubochet, J.; Vogel, H.; Ghosh, R. (1998). The reaction centre of the photounit of; Rhodospirillum rubrum; is anchored to the light-harvesting complex with four-fold rotational disorder. Photosynth. Research, 55, 363-368.
Stahlberg, H; Dubochet, J; Vogel, H; Ghosh, R (1998). Are the light-harvesting I complexes from Rhodospirillum rubrum arranged around the reaction centre in a square geometry?. Journal of molecular biology, 282(4), 819-31.
Liley, M; Gourdon, D; Stamou, D; Meseth, U; Fischer, TM; Lautz, C; Stahlberg, H; Vogel, H; Burnham, NA; Duschl, C (1998). Friction anisotropy and asymmetry of a compliant monolayer induced by a small molecular tilt. Science (New York, N.Y.), 280(5361), 273-5.
1997
Neff, D; Tripathi, S; Middendorf, K; Stahlberg, H; Butt, HJ; Bamberg, E; Dencher, NA (1997). Chloroplast F0F1 ATP Synthase Imaged by Atomic Force Microscopy. Journal of structural biology, 119(2), 139-48.
1996
Duschl, C.; Liley, M.; Lang, H.; Ghandi, A.; Zakeeruddin, S.; Stahlberg, H.; Dubochet, J.; Nemetz, A.; Knoll, W.; Vogel, H. (1996). Sulphur-bearing lipids for the covalent attachment of supported lipid bilayers to gold surfaces: a detailed characterisation and analysis. Materials Science & Engineering C, 4, 7-18.

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