SNI / Biozentrum Lecture

The development of cryo-electron microscopy

Mini-symposium with Nobel laureate Jacques Dubochet

11 April 2018, 4 - 6 pm
Lecture Hall 1, Biozentrum/Pharmazentrum, Klingelbergstrasse 50/70, Basel

Last year, Prof. em. Jacques Dubochet, along with two other scientists, was awarded the Nobel Prize in Chemistry for developing cryo-electron microscopy. In a symposium organized by the Swiss Nanoscience Institute (SNI) and the Biozentrum of the University of Basel, Prof. em. Jacques Dubochet and two of his long-time colleagues, Prof. em. Ueli Aebi und Prof. em Andreas Engel will provide fascinating insights into this technology. Flyer download

04:00 Welcome address
Prof. Christian Schönenberger, Swiss Nanoscience Institute, University of Basel
04.10Swiss efforts into cryo-electron microscopy
Prof. em. Ueli Aebi, Biozentrum, University of Basel
04.30A technology recognized by the Nobel Prize 2017
Prof. em. Jacques Dubouchet, University of Lausanne
05.10Structural Biology goes from x-rays to electrons
Prof. em. Andreas Engel, Biozentrum, University of Basel
05.40Closing remarks
Prof. Christian Schönenberger

Prof. em. Ueli Aebi

Ueli Aebi was Professor of Structural Biology at the Biozentrum from 1986 to 2011. He was co-founder and the director of the Maurice E. Müller Institute for Structural Biology, as well as a member of the Swiss Nanoscience Institute and the NCCR Nanoscale Science. In 1977, Ueli Aebi had graduated in biophysics in the lab of Prof. Eduard Kellenberger, one of the founding professors of the Biozentrum. His pioneering work led to the development of new applications that have opened the doors to nano-medicine.

Prof. em. Jacques Dubochet
The biophysicist Jacques Dubochet is the co-recipient of the 2017 Nobel Prize in Chemistry for developing cryo-electron microscopy for the high-resolution structure determination of biomolecules in solution. Jacques Dubochet studied physics at the EPFL. From 1971 to 1978, he carried out research at the University of Geneva and at the Biozentrum where in 1974 he received his PhD from Eduard Kellenberger. Subsequently, he became group leader at the European Molecular Biology Laboratory (EMBL) in Heidelberg. From 1987 until his retirement in 2007, he was professor at the University of Lausanne.

Prof. em. Andreas Engel
Andreas Engel pioneered the application of scanning transmission electron microscopy (STEM) and atomic force microscopy (AFM) to image biomolecular complexes. Andreas Engel who had received his PhD in 1972 from the University of Bern, joined the Biozentrum in 1974 where he established a STEM platform in Eduard Kellenberger’s group. In 1986, Engel became Professor of Structural Biology. Together with Ueli Aebi he established the Maurice E. Müller Institute for Structural Biology and together with colleagues from the Biozentrum and the Departments of Chemistry and Physics, he established the nano study program at the Swiss Nanoscience Institute.