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Sorg, Isabel; Schmutz, Christoph; Lu, Yun-Yueh; Fromm, Katja; Siewert, Lena K.; Bögli, Alexandra; Strack, Kathrin; Harms, Alexander; Dehio, Christoph (2020). A Bartonella effector acts as signaling hub for intrinsic STAT3 activation to trigger anti-inflammatory responses. Cell host & microbe, 27 (3), 476-485.

Dietz, Nikolaus Balthasar; Huber, Markus; Sorg, Isabel; Goepfert, Arnaud; Harms, Alexander; Schirmer, Tilman; Dehio, Christoph (2020). Structural basis for selective targeting of Rac subfamily GTPases by a bacterial effector protein. , bioRxiv. . , 25.


Dirmeier, Simon; Emmenlauer, Mario; Dehio, Christoph; Beerenwinkel, Niko (2019). PyBDA: a command line tool for automated analysis of big biological data sets. BMC bioinformatics, 20 (1), 564.

Balaban, Nathalie Q.; Helaine, Sophie; Lewis, Kim; Ackermann, Martin; Aldridge, Bree; Andersson, Dan I.; Brynildsen, Mark P.; Bumann, Dirk; Camilli, Andrew; Collins, James J.; Dehio, Christoph; Fortune, Sarah M.; Ghigo, Jean-Marc; Hardt, Wolf-Dietrich; Harms, Alexander; Heinemann, Matthias; Hung, Deborah T.; Jenal, Urs; Levin, Bruce R.; Michiels, Jan; Storz, Gisela; Tan, Man-Wah; Tenson, Tanel; Van Melderen, Laurence; Zinkernagel, Annelies (2019). Definitions and guidelines for research on antibiotic persistence. Nature Reviews Microbiology, 17 (7), 441-448.

Casanova, Alain; Low, Shyan Huey; Québatte, Maxime; Sedzicki, Jaroslaw; Tschon, Therese; Ketterer, Maren; Smith, Kevin; Emmenlauer, Mario; Ben-Tekaya, Houchaima; Dehio, Christoph (2019). A Role for the VPS Retromer in Brucella Intracellular Replication Revealed by Genomewide siRNA Screening. mSphere, 4 (3), e00380-19.

Québatte, Maxime; Dehio, Christoph (2019). Bartonella gene transfer agent: Evolution, function, and proposed role in host adaptation. Cellular microbiology, 21 (11), e13068.

Wagner, Alexander; Tittes, Colin; Dehio, Christoph (2019). Versatility of the BID Domain: Conserved Function as Type-IV-Secretion-Signal and Secondarily Evolved Effector Functions Within; Bartonella; -Infected Host Cells. Frontiers in Microbiology, 10, 921.

Cunrath, Olivier; Meinel, Dominik M.; Maturana, Pauline; Fanous, Joseph; Buyck, Julien M.; Saint Auguste, Pamela; Seth-Smith, Helena M. B.; Körner, Jonas; Dehio, Christoph; Trebosc, Vincent; 10 Kemmer, Christian; Neher, Richard; Egli, Adrian; Bumann, Dirk; 19 (2019). Quantitative contribution of efflux to multi-drug resistance of clinical Escherichia coli and Pseudomonas aeruginosa strains. EBioMedicine, 41, 479-487.

Wagner, Alexander; Dehio, Christoph (2019). Role of distinct type-IV-secretion systems and secreted effector sets in host adaptation by pathogenic Bartonella species. Cellular microbiology, 21 (3), e13004.

Liu, Yansheng; Mi, Yang; Mueller, Torsten; Kreibich, Saskia; Williams, Evan G.; Van Drogen, Audry; Borel, Christelle; Frank, Max; Germain, Pierre-Luc; Bludau, Isabell; Mehnert, Martin; Seifert, Michael; Emmenlauer, Mario; Sorg, Isabel; Bezrukov, Fedor; Sloan Bena, Frederique; Zhou, Hu; Dehio, Christoph; Testa, Giuseppe; Saez-Rodriguez, Julio; Antonarakis, Stylianos E.; Hardt, Wolf-Dietrich; Aebersold, Ruedi (2019). Multi-omic measurements of heterogeneity in HeLa cells across laboratories. Nature Biotechnology, 37 (3), 314-322.


Daga, Neha; Eicher, Simone; Kannan, Abhilash; Casanova, Alain; Low, Shyan H.; Kreibich, Saskia; Andritschke, Daniel; Emmenlauer, Mario; Jenkins, Jeremy L.; Hardt, Wolf-Dietrich; Greber, Urs F.; Dehio, Christoph; von Mering, Christian (2018). Growth-restricting effects of siRNA transfections: a largely deterministic combination of off-target binding and hybridization-independent competition. Nucleic acids research, 46 (18), 9309-9320.

Srivatsa, Sumana; Kuipers, Jack; Schmich, Fabian; Eicher, Simone; Emmenlauer, Mario; Dehio, Christoph; Beerenwinkel, Niko (2018). Improved pathway reconstruction from RNA interference screens by exploiting off-target effects. Bioinformatics, 34 (13), i519-i527.

Lobet, Elodie; Willemart, Kevin; Ninane, Noëlle; Demazy, Catherine; Sedzicki, Jaroslaw; Lelubre, Christophe; De Bolle, Xavier; Renard, Patricia; Raes, Martine; Dehio, Christoph; Letesson, Jean-Jacques; Arnould, Thierry (2018). Mitochondrial fragmentation affects neither the sensitivity to TNFα-induced apoptosis of Brucella-infected cells nor the intracellular replication of the bacteria. Scientific reports, 8 (1), 5173.


Dehio, Christoph; Bumann, Dirk (2017). Editorial overview: Bacterial systems biology. Current Opinion in Microbiology, 39, viii-xi.

Omasits, Ulrich; Varadarajan, Adithi R.; Schmid, Michael; Goetze, Sandra; Melidis, Damianos; Bourqui, Marc; Nikolayeva, Olga; Québatte, Maxime; Patrignani, Andrea; Dehio, Christoph; Frey, Juerg E.; Robinson, Mark D.; Wollscheid, Bernd; Ahrens, Christian H. (2017). An integrative strategy to identify the entire protein coding potential of prokaryotic genomes by proteogenomics. Genome Research, 27 (12), 2083-2095.

Harms, Alexander; Liesch, Marius; Körner, Jonas; Québatte, Maxime; Engel, Philipp; Dehio, Christoph (2017). A bacterial toxin-antitoxin module is the origin of inter-bacterial and inter-kingdom effectors of Bartonella. PLoS Genetics, 13 (10), e1007077.

Québatte, Maxime; Dehio, Christoph (2017). Systems-level interference strategies to decipher host factors involved in bacterial pathogen interaction: from RNAi to CRISPRi. Current Opinion in Microbiology, 39, 34-41.

Québatte, Maxime; Christen, Matthias; Harms, Alexander; Körner, Jonas; Christen, Beat; Dehio, Christoph (2017). Gene Transfer Agent Promotes Evolvability within the Fittest Subpopulation of a Bacterial Pathogen. Cell Systems, 4 (6), 611-621.e6.

González-Prieto, Coral; Gabriel, Richard; Dehio, Christoph; Schmidt, Manfred; Llosa, Matxalen (2017). The Conjugative Relaxase TrwC Promotes Integration of Foreign DNA in the Human Genome. Applied and Environmental Microbiology, 83 (12), e00207-17.

Harms, Alexander; Segers, Francisca H. I. D.; Quebatte, Maxime; Mistl, Claudia; Manfredi, Pablo; Körner, Jonas; Chomel, Bruno B.; Kosoy, Michael; Maruyama, Soichi; Engel, Philipp; Dehio, Christoph (2017). Evolutionary Dynamics of Pathoadaptation Revealed by Three Independent Acquisitions of the VirB/D4 Type IV Secretion System in Bartonella. Genome biology and evolution, 9 (3), 761-776.

Riba, Andrea; Emmenlauer, Mario; Chen, Amy; Sigoillot, Frederic; Cong, Feng; Dehio, Christoph; Jenkins, Jeremy; Zavolan, Mihaela (2017). Explicit Modeling of siRNA-Dependent On- and Off-Target Repression Improves the Interpretation of Screening Results. Cell Systems, 4 (2), 182-193.

Stanger, Frédéric V.; de Beer, Tjaart A. P.; Dranow, David M.; Schirmer, Tilman; Phan, Isabelle; Dehio, Christoph (2017). The BID Domain of Type IV Secretion Substrates Forms a Conserved Four-Helix Bundle Topped with a Hook. Structure, 25 (1), 203-211.


Stanger, Frédéric V.; Harms, Alexander; Dehio, Christoph; Schirmer, Tilman (2016). Crystal Structure of the Escherichia coli Fic Toxin-Like Protein in Complex with Its Cognate Antitoxin. PLoS ONE, 11 (9), e0163654.

Andritschke, Daniel; Dilling, Sabrina; Emmenlauer, Mario; Welz, Tobias; Schmich, Fabian; Misselwitz, Benjamin; Rämö, Pauli; Rottner, Klemens; Kerkhoff, Eugen; Wada, Teiji; Penninger, Josef M.; Beerenwinkel, Niko; Horvath, Peter; Dehio, Christoph; Hardt, Wolf-Dietrich (2016). A Genome-Wide siRNA Screen Implicates Spire1/2 in SipA-Driven Salmonella Typhimurium Host Cell Invasion. PLoS ONE, 11 (9), e0161965.

Casanova, Alain; Low, Shyan H.; Emmenlauer, Mario; Conde-Alvarez, Raquel; Salcedo, Suzana P.; Gorvel, Jean-Pierre; Dehio, Christoph (2016). Microscopy-based Assays for High-throughput Screening of Host Factors Involved in Brucella Infection of Hela Cells. Journal of Visualized Experiments, (114), e54263.

Stanger, Frédéric V.; Burmann, Björn M.; Harms, Alexander; Aragão, Hugo; Mazur, Adam; Sharpe, Timothy; Dehio, Christoph; Hiller, Sebastian; Schirmer, Tilman (2016). Intrinsic regulation of FIC-domain AMP-transferases by oligomerization and automodification. Proceedings of the National Academy of Sciences of the United States of America, 113 (5), E529-37.

Harms, Alexander; Stanger, Frédéric Valentin; Dehio, Christoph (2016). Biological Diversity and Molecular Plasticity of FIC Domain Proteins. Annual Reviews of Microbiology, 70, 341-60.


Kreibich, Saskia; Emmenlauer, Mario; Fredlund, Jennifer; Rämö, Pauli; Münz, Christian; Dehio, Christoph; Enninga, Jost; Hardt, Wolf-Dietrich (2015). Autophagy Proteins Promote Repair of Endosomal Membranes Damaged by the Salmonella Type Three Secretion System 1. Cell host & microbe, 18 (5), 527-37.

Schmich, Fabian; Szczurek, Ewa; Kreibich, Saskia; Dilling, Sabrina; Andritschke, Daniel; Casanova, Alain; Low, Shyan Huey; Eicher, Simone; Muntwiler, Simone; Emmenlauer, Mario; Rämo, Pauli; Conde-Alvarez, Raquel; von Mering, Christian; Hardt, Wolf-Dietrich; Dehio, Christoph; Beerenwinkel, Niko (2015). Erratum to: gespeR: a statistical model for deconvoluting off-target-confounded RNA interference screens. Genome Biology, 16 (233), 233.

Schmich, Fabian; Szczurek, Ewa; Kreibich, Saskia; Dilling, Sabrina; Andritschke, Daniel; Casanova, Alain; Low, Shyan Huey; Eicher, Simone; Muntwiler, Simone; Emmenlauer, Mario; Rämö, Pauli; Conde-Alvarez, Raquel; von Mering, Christian; Hardt, Wolf-Dietrich; Dehio, Christoph; Beerenwinkel, Niko (2015). gespeR: a statistical model for deconvoluting off-target-confounded RNA interference screens. Genome Biology, 16 (220), 220.

Harms, Alexander; Stanger, Frédéric Valentin; Scheu, Patrick Daniel; de Jong, Imke Greet; Goepfert, Arnaud; Glatter, Timo; Gerdes, Kenn; Schirmer, Tilman; Dehio, Christoph (2015). Adenylylation of Gyrase and Topo IV by FicT Toxins Disrupts Bacterial DNA Topology. Cell Reports, 12 (9), 1497-507.

Siebourg-Polster, Juliane; Mudrak, Daria; Emmenlauer, Mario; Rämö, Pauli; Dehio, Christoph; Greber, Urs; Fröhlich, Holger; Beerenwinkel, Niko (2015). NEMix: single-cell nested effects models for probabilistic pathway stimulation. PLoS Computational Biology, 11 (4), e1004078.

Kühbacher, Andreas; Emmenlauer, Mario; Rämö, Pauli; Kafai, Natasha; Dehio, Christoph; Cossart, Pascale; Pizarro-Cerdá, Javier (2015). Genome-Wide siRNA Screen Identifies Complementary Signaling Pathways Involved in Listeria Infection and Reveals Different Actin Nucleation Mechanisms during Listeria Cell Invasion and Actin Comet Tail Formation. mBio, 6 (3), e00598-15.


Siamer, Sabrina; Dehio, Christoph (2014). New insights into the role of Bartonella effector proteins in pathogenesis. Current Opinion in Microbiology, 23, 80-5.

Stanger, Frédéric V.; Dehio, Christoph; Schirmer, Tilman (2014). Structure of the N-terminal gyrase B fragment in complex with ADP⋅Pi reveals rigid-body motion induced by ATP hydrolysis. PLoS ONE, 9 (9), e107289.

Okujava, Rusudan; Guye, Patrick; Lu, Yun-Yueh; Mistl, Claudia; Polus, Florine; Vayssier-Taussat, Muriel; Halin, Cornelia; Rolink, Antonius G.; Dehio, Christoph (2014). A translocated effector required for bartonella dissemination from derma to blood safeguards migratory host cells from damage by co-translocated effectors. PLoS Pathogens, 10 (6).

Pieles, Kathrin; Glatter, Timo; Harms, Alexander; Schmidt, Alexander; Dehio, Christoph (2014). An experimental strategy for the identification of AMPylation targets from complex protein samples. Proteomics, 14 (9), 1048-1052.

Franceschini, Andrea; Meier, Roger; Casanova, Alain; Kreibich, Saskia; Daga, Neha; Andritschke, Daniel; Dilling, Sabrina; Rämö, Pauli; Emmenlauer, Mario; Kaufmann, Andreas; Conde-Álvarez, Raquel; Low, Shyan Huey; Pelkmans, Lucas; Helenius, Ari; Hardt, Wolf-Dietrich; Dehio, Christoph; von Mering, Christian (2014). Specific inhibition of diverse pathogens in human cells by synthetic microRNA-like oligonucleotides inferred from RNAi screens. Proceedings of the National Academy of Sciences, 111 (12), 4548-53.

Stekhoven, Daniel J.; Omasits, Ulrich; Quebatte, Maxime; Dehio, Christoph; Ahrens, Christian H. (2014). Proteome-wide identification of predominant subcellular protein localizations in a bacterial model organism. Journal of Proteomics, 99, 123-37.

Stekhoven, Daniel J.; Omasits, Ulrich; Quebatte, Maxime; Dehio, Christoph; Ahrens, Christian H. (2014). Proteome-wide identification of predominant subcellular protein localizations in a bacterial model organism. Journal of Proteomics, 99, 123-37.

Rämö, P; Drewek, A; Arrieumerlou, C; Beerenwinkel, N; Ben-Tekaya, H; Bühlmann, P; Cardel, B; Casanova, A; Conde-Alvarez, R; Cossart, P; Csúcs, G; Eicher, S; Emmenlauer, M; Greber, U; Hardt, W-D; Helenius, A; Kasper, C; Kaufmann. A,; Kreibich, S; Kühbacher, A; Kunszt, P.; Low, SH; Mercer, J; Mudrak, D; Muntwiler, S; Pelkmans, L; Pizarro-Cerdá, J; Podvinec, M; Pujadas, E; Rinn, B; Rouilly, V; Schmich, F; Siebourg, J; Snijder, B; Stebler, M; Studer, G; Szczurek, E; Truttmann, M; von Mering, C; Vonderheit, A; Yakimovich, A; Dehio, C (2014). Simultaneous analysis of large-scale RNAi screens for pathogen entry. BMC Genomics, 15, 1162.


Quebatte, Maxime; Dick, Mathias S.; Kaever, Volkhard; Schmidt, Alexander; Dehio, Christoph (2013). Dual input control : activation of the Bartonella henselae VirB/D4 Type IV secretion system by the stringent sigma factor RpoH1 and the BatR/BatS two component system. Molecular microbiology, 90 (4), 756-775.

Goepfert, Arnaud; Stanger, Frédéric V.; Dehio, Christoph; Schirmer, Tilman (2013). Conserved inhibitory mechanism and competent ATP binding mode for adenylyltransferases with fic fold. PLoS ONE, 8 (5), e64901.

Ben-Tekaya, H.; Gorvel, J. P.; Dehio, C. (2013). Bartonella and Brucella - weapons and strategies for stealth attack. Cold Spring Harbor Perspectives in Medicine, 3 (8), a010231.

Alperi, A.; Larrea, D.; Fernández-González, E.; Dehio, C.; Zechner, E. L.; Llosa, M. (2013). A translocation motif in relaxase TrwC specifically affects recruitment by its conjugative Type IV Secretion System. Journal of Bacteriology, 195 (22), 4999-5006.

Eicher, Simone C; Dehio, Christoph (2013). Systems-level analysis of host-pathogen interaction using RNA interference. New biotechnology, 30 (3), 308-13.

Rolain, J. M.; Vayssier-Taussat, M.; Saisongkorh, W.; Merhej, V.; Gimenez, G.; Robert, C.; Le Rhun, D.; Dehio, C.; Raoult, D. (2013). Partial disruption of translational and posttranslational machinery reshapes growth rates of Bartonella birtlesii. mBio, 4 (2), e00115-13.

Omasits, U.; Quebatte, M.; Stekhoven, D. J.; Fortes, C.; Roschitzki, B.; Robinson, M. D.; Dehio, C.; Ahrens, C. H. (2013). Directed shotgun proteomics guided by saturated RNA-seq identifies a complete expressed prokaryotic proteome. Genome Research, 23 (11), 1916-27.

Farhan, Muhammad; Ruusuvuori, Pekka; Emmenlauer, Mario; Rämö, Pauli; Dehio, Christoph; Yli-Harja, Olli (2013). Multi-scale Gaussian representation and outline-learning based cell image segmentation. BMC Bioinformatics, 14 Suppl 10, S6.

Kühbacher, Andreas; Gouin, Edith; Mercer, Jason; Emmenlauer, Mario; Dehio, Christoph; Cossart, Pascale; Pizarro-Cerdá, Javier (2013). Imaging InlC secretion to investigate cellular infection by the bacterial pathogen Listeria monocytogenes. Journal of Visualized Experiments, 79 (79), e51043.

Lu, Yun-Yueh; Franz, Bettina; Truttmann, Matthias C.; Riess, Tanja; Gay-Fraret, Jeremie; Faustmann, Marco; Kempf, Volkhard A. J.; Dehio, Christoph (2013). Bartonella henselae trimeric autotransporter adhesin BadA expression interferes with effector translocation by the VirB/D4 type IV secretion system. Cellular microbiology, 15 (5), 759-778.

Goepfert, Arnaud; Harms, Alexander; Schirmer, Tilman; Dehio, Christoph: Type II Toxin-Antitoxin Loci: The fic Family, in: Gerdes, Kenn(Ed.). (2013). Prokaryotic Toxin-Antitoxins, Heidelberg: Springer Verlag, 177-187.


Engel, Philipp; Goepfert, Arnaud; Stanger, Frédéric V.; Harms, Alexander; Schmidt, Alexander; Schirmer, Tilman; Dehio, Christoph (2012). Adenylylation control by intra- or intermolecular active-site obstruction in Fic proteins. Nature, 482 (7383), 107-10.

Pulliainen, Arto Tapio; Dehio, Christoph (2012). Persistence of Bartonella spp. stealth pathogens : from subclinical infections to vasoproliferative tumor formation. FEMS Microbiology Reviews, 36 (3), 563-599.

Harms, Alexander; Dehio, Christoph (2012). Intruders below the Radar : Molecular Pathogenesis of Bartonella spp. Clinical microbiology reviews, 25 (1), 42-78.

Dehio, C.; Berry, C.; Bartenschlager, R. (2012). Persistent intracellular pathogens. FEMS Microbiology Reviews, 36 (3), 513.

Eicher, S. C.; Dehio, C. (2012). Bartonella entry mechanisms into mammalian host cells. Cellular Microbiology, 14 (8), 1166-73.

Pulliainen, A. T.; Pieles, K.; Brand, C. S.; Hauert, B.; Böhm, A.; Quebatte, M.; Wepf, A.; Gstaiger, M.; Aebersold, R.; Dessauer, C. W.; Dehio, C. (2012). Bacterial effector binds host cell adenylyl cyclase to potentiate Gαs-dependent cAMP production. Proceedings of the National Academy of Sciences of the United States of America, 109 (24), 9581-6.

Llosa, M.; Schröder, G.; Dehio, C. (2012). New perspectives into bacterial DNA transfer to human cells. Trends in Microbiology, 20 (8), 355-9.


Truttmann, Matthias C.; Misselwitz, Benjamin; Huser, Sonja; Hardt, Wolf-Dietrich; Critchley, David R.; Dehio, Christoph (2011). Bartonella henselae engages inside-out and outside-in signaling by integrin β1 and talin1 during invasome-mediated bacterial uptake. Journal of Cell Science, 124 (Pt21), 3591-602.

Truttmann, Matthias C.; Guye, Patrick; Dehio, Christoph (2011). BID-F1 and BID-F2 domains of Bartonella henselae effector protein BepF trigger together with BepC the formation of invasome structures. PLoS ONE, 6 (10), e25106.

Fernández-González, Esther; de Paz, Héctor D; Alperi, Anabel; Agúndez, Leticia; Faustmann, Marco; Sangari, Félix J; Dehio, Christoph; Llosa, Matxalen (2011). Transfer of R388 derivatives by a pathogenesis-associated type IV secretion system into both bacteria and human cells. Journal of bacteriology, 193 (22), 6257-65.

Schroeder, Gunnar; Schuelein, Ralf; Quebatte, Maxime; Dehio, Christoph (2011). Conjugative DNA transfer into human cells by the VirB/VirD4 type IV secretion system of the bacterial pathogen Bartonella henselae. Proceedings of the National Academy of Sciences of the United States of America, 108 (35), 14643-14648.

Engel, Philipp; Salzburger, Walter; Liesch, Marius; Chang, Chao-Chin; Maruyama, Soichi; Lanz, Christa; Calteau, Alexandra; Lajus, Aurélie; Médigue, Claudine; Schuster, Stephan C.; Dehio, Christoph (2011). Parallel evolution of a type IV secretion system in radiating lineages of the host-restricted bacterial pathogen Bartonella. PLoS Genetics, 7 (2), e1001296.

Palanivelu, D. V.; Goepfert, A.; Meury, M.; Guye, P.; Dehio, C.; Schirmer, T. (2011). Fic domain catalyzed adenylylation: Insight provided by the structural analysis of the type IV secretion system effector BepA. Protein Science, 20 (3), 492-9.

Truttmann, M. C.; Rhomberg, T. A.; Dehio, C. (2011). Combined action of the type IV secretion effector proteins BepC and BepF promotes invasome formation of Bartonella henselae on endothelial and epithelial cells. Cellular Microbiology, 13 (2), 284-99.

Mietze, A.; Morick, D.; Kohler, H.; Harrus, S.; Dehio, C.; Nolte, I.; Goethe, R. (2011). Combined MLST and AFLP typing of Bartonella henselae isolated from cats reveals new sequence types and suggests clonal evolution. Veterinary Microbiology, 148 (2-4), 238-45.


Scheidegger, F.; Quebatte, M.; Mistl, C.; Dehio, C. (2010). The Bartonella henselae VirB/Bep system interferes with vascular endothelial growth factor (VEGF) signalling in human vascular endothelial cells. Cellular Microbiology, 13 (3), 419-431.

Vayssier-Taussat, Muriel; Le Rhun, Danielle; Deng, Hong Kuan; Biville, Francis; Cescau, Sandra; Danchin, Antoine; Marignac, Geneviève; Lenaour, Evelyne; Boulouis, Henri Jean; Mavris, Maria; Arnaud, Lionel; Yang, Huanming; Wang, Jing; Quebatte, Maxime; Engel, Philipp; Saenz, Henri; Dehio, Christoph (2010). The Trw type IV secretion system of Bartonella mediates host-specific adhesion to erythrocytes. PLoS Pathogens, 6 (6), e1000946.

Quebatte, Maxime; Dehio, Michaela; Tropel, David; Basler, Andrea; Toller, Isabella; Raddatz, Guenter; Engel, Philipp; Huser, Sonja; Schein, Hermine; Lindroos, Hillevi L.; Andersson, Siv G. E.; Dehio, Christoph (2010). The BatR/BatS two-component regulatory system controls the adaptive response of Bartonella henselae during human endothelial cell infection. Journal of bacteriology, 192 (13), 3352-3367.

de Paz, Héctor D.; Larrea, Delfina; Zunzunegui, Sandra; Dehio, Christoph; de la Cruz, Fernando; Llosa, Matxalen (2010). Functional dissection of the conjugative coupling protein TrwB. Journal of bacteriology, 192 (11), 2655-69.


Engel, P.; Dehio, C. (2009). Genomics of Host-Restricted Pathogens of the Genus Bartonella. Genome dynamics, 6, 158-69.

Llosa, Matxalen; Roy, Craig; Dehio, Christoph (2009). Bacterial type IV secretion systems in human disease. Molecular microbiology, 73 (2), 141-51.

Scheidegger, F; Ellner, Y; Guye, P; Rhomberg, T A; Weber, H; Augustin, H G; Dehio, C (2009). Distinct activities of Bartonella henselae type IV secretion effector proteins modulate capillary-like sprout formation. Cellular Microbiology, 11 (7), 1088-101.

Selbach, Matthias; Paul, Florian Ernst; Brandt, Sabine; Guye, Patrick; Daumke, Oliver; Backert, Steffen; Dehio, Christoph; Mann, Matthias (2009). Host cell interactome of tyrosine-phosphorylated bacterial proteins. Cell Host & Microbe, 5 (4), 397-403.

Rhomberg, Thomas A; Truttmann, Matthias C; Guye, Patrick; Ellner, Yvonne; Dehio, Christoph (2009). A translocated protein of Bartonella henselae interferes with endocytic uptake of individual bacteria and triggers uptake of large bacterial aggregates via the invasome. Cellular Microbiology, 11 (6), 927-45.

Chomel, B. B.; Boulouis, H. -J.; Breitschwerdt, E. B.; Kasten, R. W.; Vayssier-Taussat, M.; Birtles, R. J.; Koehler, J. E.; Dehio, C. (2009). Ecological fitness and strategies of adaptation of Bartonella species to their hosts and vectors. Veterinary Research, 40 (2), 29.

Pulliainen, Arto Tapio; Dehio, Christoph (2009). Bartonella henselae : subversion of vascular endothelial cell functions by translocated bacterial effector proteins. The international journal of biochemistry & cell biology, 41 (3), 507-10.


Dehio, Christoph (2008). Infection-associated type IV secretion systems of Bartonella and their diverse roles in host cell interaction. Cellular Microbiology, 10 (8), 1591-8.


Saenz, Henri L; Engel, Philipp; Stoeckli, Michèle C; Lanz, Christa; Raddatz, Günter; Vayssier-Taussat, Muriel; Birtles, Richard; Schuster, Stephan C; Dehio, Christoph (2007). Genomic analysis of Bartonella identifies type IV secretion systems as host adaptability factors. Nature Genetics, 39 (12), 1469-76.


Schmid, M. C.; Scheidegger, F.; Dehio, M.; Balmelle-Devaux, N.; Schulein, R.; Guye, P.; Chennakesava, C. S.; Biedermann, B.; Dehio, C. (2006). A translocated bacterial protein protects vascular endothelial cells from apoptosis. PLoS Pathogens, 2 (11), 1083-1097.


Mavris, Maria; Saenz, Henri; Monteil, Martine; Boulouis, Henri-Jean; Dehio, Christoph; Vayssier-Taussat, Muriel (2005). Characterization of genes involved in long-term bacteremia in mice by Bartonella birtlesii. Annals of the New York Academy of Sciences, 1063, 312-4.

de Paz, Héctor D; Sangari, Félix J; Bolland, Silvia; García-Lobo, Juan M; Dehio, Christoph; de la Cruz, Fernando; Llosa, Matxalen (2005). Functional interactions between type IV secretion systems involved in DNA transfer and virulence. Microbiology, 151 (Pt11), 3505-16.

Lindroos, Hillevi L; Mira, Alex; Repsilber, Dirk; Vinnere, Olga; Näslund, Kristina; Dehio, Michaela; Dehio, Christoph; Andersson, Siv G E (2005). Characterization of the genome composition of Bartonella koehlerae by microarray comparative genomic hybridization profiling. Journal of bacteriology, 187 (17), 6155-65.

Fiedler, Jörg; Leucht, Frank; Waltenberger, Johannes; Dehio, Christoph; Brenner, Rolf E (2005). VEGF-A and PlGF-1 stimulate chemotactic migration of human mesenchymal progenitor cells. Biochemical and Biophysical Research Communications, 334 (2), 561-8.

Schulein, Ralf; Guye, Patrick; Rhomberg, Thomas A; Schmid, Michael C; Schröder, Gunnar; Vergunst, Annette C; Carena, Ilaria; Dehio, Christoph (2005). A bipartite signal mediates the transfer of type IV secretion substrates of Bartonella henselae into human cells. Proceedings of the National Academy of Sciences of the United States of America, 102 (3), 856-61.

Schröder, Gunnar; Dehio, Christoph (2005). Virulence-associated type IV secretion systems of Bartonella. Trends in microbiology, 13 (7), 336-42.

Dehio, C. (2005). Bartonella-host-cell interactions and vascular tumour formation. Nature Reviews Microbiology, 3 (8), 621-31.

Saenz, H. L.; Dehio, C. (2005). Signature-tagged mutagenesis : technical advances in a negative selection method for virulence gene identification. Current Opinion in Microbiology, 8 (5), 612-9.


Niehus, Eike; Gressmann, Helga; Ye, Fang; Schlapbach, Ralph; Dehio, Michaela; Dehio, Christoph; Stack, Allison; Meyer, Thomas F; Suerbaum, Sebastian; Josenhans, Christine (2004). Genome-wide analysis of transcriptional hierarchy and feedback regulation in the flagellar system of Helicobacter pylori. Molecular microbiology, 52 (4), 947-61.

Zahringer, U.; Lindner, B.; Knirel, Y. A.; van den Akker, W. M. R.; Hiestand, R.; Heine, H.; Dehio, C. (2004). Structure and biological activity of the short-chain lipopolysaccharide from Bartonella henselae ATCC 49882T. Journal of Biological Chemistry, 279 (20), 21046-54.

Schmid, Michael C; Schulein, Ralf; Dehio, Michaela; Denecker, Geertrui; Carena, Ilaria; Dehio, Christoph (2004). The VirB type IV secretion system of Bartonella henselae mediates invasion, proinflammatory activation and antiapoptotic protection of endothelial cells. Molecular microbiology, 52 (1), 81-92.

Dehio, Christoph (2004). Molecular and cellular basis of bartonella pathogenesis. Annual review of microbiology, 58, 365-90.

Dehio, Christoph; Sauder, Ursula; Hiestand, Rosemarie (2004). Isolation of Bartonella schoenbuchensis from Lipoptena cervi, a blood-sucking arthropod causing deer ked dermatitis. Journal of clinical microbiology, 42 (11), 5320-3.

Rhomberg, Thomas A; Karlberg, Olof; Mini, Thierry; Zimny-Arndt, Ursula; Wickenberg, Ulrika; Röttgen, Marlene; Jungblut, Peter R; Jenö, Paul; Andersson, Siv G E; Dehio, Christoph (2004). Proteomic analysis of the sarcosine-insoluble outer membrane fraction of the bacterial pathogen Bartonella henselae. Proteomics, 4 (10), 3021-33.


Heil, Matthias; Mitnacht-Krauss, Rita; Issbrücker, Katja; van den Heuvel, Joop; Dehio, Christoph; Schaper, Wolfgang; Clauss, Matthias; Weich, Herbert A (2003). An engineered heparin-binding form of VEGF-E (hbVEGF-E) : biological effects in vitro and mobilizatiion of precursor cells. Angiogenesis, 6 (3), 201-11.

Autiero, Monica; Waltenberger, Johannes; Communi, Didier; Kranz, Andrea; Moons, Lieve; Lambrechts, Diether; Kroll, Jens; Plaisance, Stephane; De Mol, Maria; Bono, Françoise; Kliche, Stefanie; Fellbrich, Guido; Ballmer-Hofer, Kurt; Maglione, Domenico; Mayr-Beyrle, Ulrike; Dewerchin, Mieke; Dombrowski, Saskia; Stanimirovic, Danica; Van Hummelen, Paul; Dehio, Christoph; Hicklin, Daniel J; Persico, Graziella; Herbert, Jean-Marc; Communi, David; Shibuya, Masabumi; Collen, Désiré; Conway, Edward M; Carmeliet, Peter (2003). Role of PlGF in the intra- and intermolecular cross talk between the VEGF receptors Flt1 and Flk1. Nature medicine, 9 (7), 936-43.

Rziha, H-J; Bauer, B; Adam, K-H; Röttgen, M; Cottone, R; Henkel, M; Dehio, C; Büttner, M (2003). Relatedness and heterogeneity at the near-terminal end of the genome of a parapoxvirus bovis 1 strain (B177) compared with parapoxvirus ovis (Orf virus). Journal of general virology, 84 (Pt5), 1111-6.

Seubert, Anja; Falch, Christine; Birtles, Richard J; Schulein, Ralf; Dehio, Christoph (2003). Characterization of the cryptic plasmid pBGR1 from Bartonella grahamii and construction of a versatile Escherichia coli-Bartonella spp. shuttle cloning vector. Plasmid, 49 (1), 44-52.

Dehio, C. (2003). Recent progress in understanding Bartonella-induced vascular proliferation. Current Opinion in Microbiology, 6 (1), 61-5.

Seubert, Anja; Hiestand, Rosemarie; de la Cruz, Fernando; Dehio, Christoph (2003). A bacterial conjugation machinery recruited for pathogenesis. Molecular microbiology, 49 (5), 1253-66.


Upalakalin, J. N.; Hemo, I.; Dehio, C.; Keshet, E.; Benjamin, L. E. (2002). Survival mechanisms of VEGF and PlGF during microvascular remodeling. Cold Spring Harbor Symposia on Quantitative Biology, 67, 181-7.

Bermond, Delphine; Boulouis, Henri-Jean; Heller, Rémy; Van Laere, Guy; Monteil, Henri; Chomel, Bruno B; Sander, Anna; Dehio, Christoph; Piémont, Yves (2002). Bartonella bovis Bermond et al. sp. nov. and Bartonella capreoli sp. nov, isolated from European ruminants. International journal of systematic and evolutionary microbiology, 52 (Pt2), 383-90.

Mayr-Wohlfart, U; Waltenberger, J; Hausser, H; Kessler, S; Günther, K-P; Dehio, C; Puhl, W; Brenner, R E (2002). Vascular endothelial growth factor stimulates chemotactic migration of primary human osteoblasts. Bone, 30 (3), 472-7.

Schülein, R.; Dehio, C. (2002). The VirB/VirD4 type IV secretion system of Bartonella is essential for establishing intraerythrocytic infection. Molecular microbiology, 46 (4), 1053-1067.

Seubert, Anja; Schulein, Ralf; Dehio, Christoph (2002). Bacterial persistence within erythrocytes : a unique pathogenic strategy of Bartonella spp. International Journal of Medical Microbiology : IJMM, 291 (6-7), 555-60.


Fuhrmann, O; Arvand, M; Göhler, A; Schmid, M; Krüll, M; Hippenstiel, S; Seybold, J; Dehio, C; Suttorp, N (2001). Bartonella henselae induces NF-kappaB-dependent upregulation of adhesion molecules in cultured human endothelial cells : possible role of outer membrane proteins as pathogenic factors. Infection and immunity, 69 (8), 5088-97.

Koesling, J; Aebischer, T; Falch, C; Schülein, R; Dehio, C (2001). Cutting edge : antibody-mediated cessation of hemotropic infection by the intraerythrocytic mouse pathogen Bartonella grahamii. Journal of immunology, 167 (1), 11-4.

Raddatz, G.; Dehio, M.; Meyer, T. F.; Dehio, C. (2001). PrimeArray : genome-scale primer design for DNA-microarray construction. Bioinformatics, 17 (1), 98-9.

Schülein, R; Seubert, A; Gille, C; Lanz, C; Hansmann, Y; Piémont, Y; Dehio, C (2001). Invasion and persistent intracellular colonization of erythrocytes : A unique parasitic strategy of the emerging pathogen Bartonella. Journal of experimental medicine, 193 (9), 1077-86.

Dehio, C (2001). Bartonella interactions with endothelial cells and erythrocytes. Trends in Microbiology, 9 (6), 279-85.

Dehio, C; Lanz, C; Pohl, R; Behrens, P; Bermond, D; Piémont, Y; Pelz, K; Sander, A (2001). Bartonella schoenbuchii sp. nov, isolated from the blood of wild roe deer. International journal of systematic and evolutionary microbiology, 51 (Pt4), 1557-65.


Freissler, E; Meyer auf der Heyde, A; David, G; Meyer, T F; Dehio, C (2000). Syndecan-1 and syndecan-4 can mediate the invasion of OpaHSPG-expressing Neisseria gonorrhoeae into epithelial cells. Cellular microbiology, 2 (1), 69-82.

Bermond, D; Heller, R; Barrat, F; Delacour, G; Dehio, C; Alliot, A; Monteil, H; Chomel, B; Boulouis, H J; Piémont, Y (2000). Bartonella birtlesii sp. nov, isolated from small mammals (Apodemus spp.). International journal of systematic and evolutionary microbiology, 50 Pt 6, 1973-9.

Andersson, S G; Dehio, C (2000). Rickettsia prowazekii and Bartonella henselae : differences in the intracellular life styles revisited. International journal of medical microbiology, 290 (2), 135-41.

Rziha, H; Henkel, M; Cottone, R; Bauer, B; Auge, U; Götz, F; Pfaff, E; Röttgen, M; Dehio, C; Büttner, M (2000). Generation of recombinant parapoxviruses: non-essential genes suitable for insertion and expression of foreign genes. Journal of biotechnology, 83 (1-2), 137-45.

Sander, A; Zagrosek, A; Bredt, W; Schiltz, E; Piémont, Y; Lanz, C; Dehio, C (2000). Characterization of Bartonella clarridgeiae flagellin (FlaA) and detection of antiflagellin antibodies in patients with lymphadenopathy. Journal of clinical microbiology, 38 (8), 2943-8.

Muenzner, P; Dehio, C; Fujiwara, T; Achtman, M; Meyer, T F; Gray-Owen, S D (2000). Carcinoembryonic antigen family receptor specificity of Neisseria meningitidis Opa variants influences adherence to and invasion of proinflammatory cytokine-activated endothelial cells. Infection and immunity, 68 (6), 3601-7.

Dehio, C; Gray-Owen, S D; Meyer, T F (2000). Host cell invasion by pathogenic Neisseriae. Subcellular biochemistry, 33, 61-96.

Gray-Owen, S. D.; Dehio, C.; Naumann, M.; Rudel, T.; Meyer, T. F.: NeisseriaPrinciples of bacterial pathogenesis, San Diego, Calif. ; London: Academic Press.


Popp, A; Dehio, C; Grunert, F; Meyer, T F; Gray-Owen, S D (1999). Molecular analysis of neisserial Opa protein interactions with the CEA family of receptors : identification of determinants contributing to the differential specificities of binding. Cellular Microbiology, 1 (2), 169-81.

Rziha, H J; Henkel, M; Cottone, R; Meyer, M; Dehio, C; Büttner, M (1999). Parapoxviruses : potential alternative vectors for directing the immune response in permissive and non-permissive hosts. Journal of biotechnology, 73 (2-3), 235-42.

Dehio, C.; Sander, A. (1999). Bartonella as emerging pathogens. Trends in microbiology, 7 (6), 226-228.

Heller, R.; Kubina, M.; Mariet, P.; Riegel, P.; Delacour, G.; Dehio, C.; Lamarque, F.; Kasten, R.; Boulouis, H. J.; Monteil, H.; Chomel, B.; Piemont, Y. (1999). Bartonella alsatica sp. nov. : a new Bartonella species isolated from the blood of wild rabbits. International Journal of Systematic Bacteriology, 49 Pt 1 (1), 283-8.

Meyer, M; Clauss, M; Lepple-Wienhues, A; Waltenberger, J; Augustin, H G; Ziche, M; Lanz, C; Büttner, M; Rziha, H J; Dehio, C (1999). A novel vascular endothelial growth factor encoded by Orf virus, VEGF-E, mediates angiogenesis via signalling through VEGFR-2 (KDR) but not VEGFR-1 (Flt-1) receptor tyrosine kinases. The EMBO journal, 18 (2), 363-74.


Dehio, C; Gray-Owen, S D; Meyer, T F (1998). The role of neisserial Opa proteins in interactions with host cells. Trends in microbiology, 6 (12), 489-95.

Heller, R.; Riegel, P.; Hansmann, Y.; Delacour, G.; Bermond, D.; Dehio, C.; Lamarque, F.; Monteil, H.; Chomel, B.; Piemont, Y. (1998). Bartonella tribocorum sp. nov. : a new Bartonella species isolated from the blood of wild rats. International Journal of Systematic Bacteriology, 48 Pt 4 (4), 1333-9.

Wang, J; Gray-Owen, S D; Knorre, A; Meyer, T F; Dehio, C (1998). Opa binding to cellular CD66 receptors mediates the transcellular traversal of Neisseria gonorrhoeae across polarized T84 epithelial cell monolayers. Molecular microbiology, 30 (3), 657-71.

Dehio, M; Knorre, A; Lanz, C; Dehio, C (1998). Construction of versatile high-level expression vectors for Bartonella henselae and the use of green fluorescent protein as a new expression marker. Gene, 215 (2), 223-9.

Dehio, C; Freissler, E; Lanz, C; Gómez-Duarte, O G; David, G; Meyer, T F (1998). Ligation of cell surface heparan sulfate proteoglycans by antibody-coated beads stimulates phagocytic uptake into epithelial cells : a model for cellular invasion by Neisseria gonorrhoeae. Experimental cell research, 242 (2), 528-39.

Dehio, M; Gómez-Duarte, O G; Dehio, C; Meyer, T F (1998). Vitronectin-dependent invasion of epithelial cells by Neisseria gonorrhoeae involves alpha(v) integrin receptors. FEBS letters, 424 (1-2), 84-8.


Gray-Owen, S D; Lorenzen, D R; Haude, A; Meyer, T F; Dehio, C (1997). Differential Opa specificities for CD66 receptors influence tissue interactions and cellular response to Neisseria gonorrhoeae. Molecular microbiology, 26 (5), 971-80.

Dehio, C.; Meyer, M.; Berger, J.; Schwarz, H.; Lanz, C. (1997). Interaction of Bartonella henselae with endothelial cells results in bacterial aggregation on the cell surface and the subsequent engulfment and internalisation of the bacterial aggregate by a unique structure, the invasome. Journal of Cell Science, 110 ( Pt 18) (18), 2141-54.

Gómez-Duarte, O G; Dehio, M; Guzmán, C A; Chhatwal, G S; Dehio, C; Meyer, T F (1997). Binding of vitronectin to opa-expressing Neisseria gonorrhoeae mediates invasion of HeLa cells. Infection and immunity, 65 (9), 3857-66.

Gray-Owen, S D; Dehio, C; Haude, A; Grunert, F; Meyer, T F (1997). CD66 carcinoembryonic antigens mediate interactions between Opa-expressing Neisseria gonorrhoeae and human polymorphonuclear phagocytes. The EMBO journal, 16 (12), 3435-45.

Dehio, C; Meyer, M (1997). Maintenance of broad-host-range incompatibility group P and group Q plasmids and transposition of Tn5 in Bartonella henselae following conjugal plasmid transfer from Escherichia coli. Journal of bacteriology, 179 (2), 538-40.

Dehio, C. (1997). Pathogenicity of Bartonella spp. Bulletin de l'Institut Pasteur, 95 (95), 197-207.


Ménard, R; Dehio, C; Sansonetti, P J (1996). Bacterial entry into epithelial cells : the paradigm of Shigella. Trends in microbiology, 4 (6), 220-6.

Ménard, R; Prévost, M C; Gounon, P; Sansonetti, P; Dehio, C (1996). The secreted Ipa complex of Shigella flexneri promotes entry into mammalian cells. Proceedings of the National Academy of Sciences of the United States of America, 93 (3), 1254-8.


Dehio, C; Prévost, M C; Sansonetti, P J (1995). Invasion of epithelial cells by Shigella flexneri induces tyrosine phosphorylation of cortactin by a pp60c-src-mediated signalling pathway. The EMBO journal, 14 (11), 2471-82.


Magrelli, A; Langenkemper, K; Dehio, C; Schell, J; Spena, A (1994). Splicing of the rolA transcript of Agrobacterium rhizogenes in Arabidopsis. Science, 266 (5193), 1986-8.

Dehio, C; Schell, J (1994). Identification of plant genetic loci involved in a posttranscriptional mechanism for meiotically reversible transgene silencing. Proceedings of the National Academy of Sciences of the United States of America, 91 (12), 5538-42.


Dehio, C; Grossmann, K; Schell, J; Schmülling, T (1993). Phenotype and hormonal status of transgenic tobacco plants overexpressing the rolA gene of Agrobacterium rhizogenes T-DNA. Plant Molecular Biology, 23 (6), 1199-210.

Dehio, C; Schell, J (1993). Stable expression of a single-copy rolA gene in transgenic Arabidopsis thaliana plants allows an exhaustive mutagenic analysis of the transgene-associated phenotype. Molecular and general genetics, 241 (3-4), 359-66.


Dehio, C; de Bruijn, F J (1992). The early nodulin gene SrEnod2 from Sesbania rostrata is inducible by cytokinin. >>The, 2 (1), 117-28.

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