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Postdoctoral and PhD student positions (100%, funded) in skeletal muscle plasticity (group of Prof. Christoph Handschin, Biozentrum/University of Basel)

How does life emerge from molecules and cells? This is the central question that motivates us. With curiosity and passion, we investigate the entire spectrum ranging from the atom to the organism. The Biozentrum of the University of Basel is one of the world’s leading life sciences institutes. With 32 groups and 500 employees, we are a dynamic and international research community that has spawned many fundamental discoveries in biology and medicine as well as several Nobel Laureates. Become part of our community!

The project:
In an interdisciplinary project supported by a Sinergia grant of the Swiss National Science Foundation, we will investigate the molecular underpinnings of gene regulation in muscle plasticity in health and disease. Thus, in close collaboration with the group of Prof. Sebastian Hiller, comprehensive analysis of RNA-binding, liquid-liquid phase separated condensate formation of transcriptional regulators, coupled to the elucidation of the corresponding structure-function aspects will be performed using various state-of-the-art technologies, spanning from molecular biology to animal (patho)physiology. We are therefore looking for a motivated and well-trained PhD and Postdoc to join the multidisciplinary team of postdocs and PhD students from the Handschin and Hiller groups performing these studies in close collaboration and constant exchange.

Your profile:
Postdoctoral applicants should have a PhD or MD/PhD, PhD student applicants a MSc or equivalent degree. A strong background in molecular and cell biology is required, optimally in the field of muscle plasticity and physiology. Additional experience in RNA-binding protein biology, liquid-liquid phase separation, NGS-based techniques and analysis (e.g. CLIP or ChIPseq), or proteomics of protein complexes and PTMs is a plus. Selection will furthermore be based on the educational background, motivation, independence and creativity of the applicant. Good knowledge of English is a requirement. The positions are funded, and salaries according to institutional guidelines.

We offer
Our international team consists of a dynamic and collaborative group of scientists, committed to work at the frontier of science and to solve fundamental questions about muscle plasticity. Successful applicants will be embedded at the interface of the Handschin and Hiller groups. The Biozentrum provides a highly stimulating collaborative research environment with a fantastic infrastructure in a brand-new building. Further, we have access to state-of-the-art technology platforms providing the lab with an optimal environment for carrying out cutting-edge interdisciplinary research.

Basel is an international city with people from 150 nations. Located on the border where three countries meet - Switzerland-Germany- France -, it is Europe’s most important life sciences hub. Basel provides a high standard of living and a rich and varied cultural atmosphere.

Application / Contact

Only online applications will be considered.

Postdoctoral applicants: https://biped2.biozentrum.unibas.ch/apply/handschinlab_postdoc_sinergia

PhD student applicants: https://biped2.biozentrum.unibas.ch/apply/handschinlab_phd_sinergia

There, enter the relevant information and upload the required PDF documents, including:

  • Your up-to-date CV with contact details of at least two referees
  • A brief personal statement, explaining how your research skills and interests align with the aims of this project and the research focus of our group (max 2 pages)
  • All required diplomas, including PhD and MSc confirmation and grades
  • List of all your publications and describe briefly (max 300 words) for up to 3 publications what was your role and why they are relevant for the job offer

Review of applications will start immediately and continue until the 15th November noon.

For any informal enquiries, please contact: christoph.handschinunibasch