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Projects

We study the cellular organization and regulation of metabolism by large macromolecular assemblies as well as giant microbial biosynthetic assembly lines. Our research builds on hybrid use of state-of-the-art cryo electron…


Projects

Regulation of skeletal muscle cell plasticity in health and disease Skeletal muscle has an enormous capacity to adapt to external stimuli including physical activity, oxygen levels, ambient temperature, nutrient availability…


Alumni

Alumni Name Position Held in Lab Current Position AGUILAR Gustavo PhD & PostDoc ALBORELLI Ilaria PhD & PostDoc Head of Data Analysis Unit, Pathology Department, University Hospital of Basel, Switzerland AYDOGAN Vahap PhD &…


Cell Sorting Guidelines

Cell Sorting Guidelines General information High-speed cell sorting can produce aerosols that may present a health hazard to facility members and users. The guidelines are designed to protect the users and staff of the FACS…


Projects

Evolution of viruses and bacteria We want to understand the dynamics of evolution and the forces that drive it. Evolution of plants and animals tend to happen over centuries of even longer time-scales. Microbial organisms,…


Projects

Role of type IV secretion systems in the establishment of chronic bacterial infections The aim of our studies is to gain a molecular understanding of the function of type IV secretion (T4S) systems in establishing persistent…


Guidelines

IMCF guidelines 1. General booking Rules: The user can book a microscope only after having received the appropriate introduction. The instruments can be booked up to 14 days in advance. During daily working hours (9-17h),…


Projects

Regulators of gene expression from stem cell differentiation to aging Our group is interested in the mechanisms that control gene expression from very early to very late in human life. In eukaryotes, gene expression is a…