Publications

Publications

Arquint C, Nigg EA. “The PLK4-STIL-SAS-6 module at the core of centriole duplication.” Biochem Soc Trans. 2016 Oct 15;44(5):1253-1263. PMID: 27911707

Renzi F, Ittig SJ, Sadovskaya I, Hess E, Lauber F, Dol M, Shin H, Mally M, Fiechter C, Sauder U, Chami M, Cornelis GR. “Evidence for a LOS and a capsular polysaccharide in Capnocytophaga canimorsus.” Sci Rep. 2016 Dec 15;6:38914. PMID: 27974829

Dinulovic I, Furrer R, Beer M, Ferry A, Cardel B, Handschin C. ”Muscle PGC-1α modulates satellite cell number and proliferation by remodeling the stem cell niche.” Skelet Muscle. 2016 Dec 2;6(1):39. PMID: 27908291

Ruder L, Takeoka A, Arber S. ”Long-Distance Descending Spinal Neurons Ensure Quadrupedal Locomotor Stability.” Neuron. 2016 Dec 7;92(5):1063-1078.. PMID: 27866798

Arnold SA, Albiez S, Bieri A, Syntychaki A, Adaixo R, McLeod RA, Goldie KN, Stahlberg H, Braun T. “Blotting-Free and Lossless Cryo-Electron Microscopy Grid Preparation from Nanoliter-Sized Protein Samples and Single-Cell Extracts.” J Struct Biol. 2016 Nov 15;. [Epub ahead of print]. PMID: 27864160

Dinulovic I, Furrer R, Di Fulvio S, Ferry A, Beer M, Handschin C. ”PGC-1α modulates necrosis, inflammatory response, and fibrotic tissue formation in injured skeletal muscle.” Skelet Muscle. 2016 Nov 8;6:38. PMID: 27833743

Broder UN, Jaeger T, Jenal U.” LadS is a calcium-responsive kinase that induces acute-to-chronic virulence switch in Pseudomonas aeruginosa.” Nat Microbiol. 2016 Oct 24;2:16184. PMID: 27775685

Stanger FV, Harms A, Dehio C, Schirmer T. “Crystal Structure of the Escherichia coli Fic Toxin-Like Protein in Complex with Its Cognate Antitoxin.” PLoS One. 2016;11(9):e0163654. PMID: 27657533

Vettiger A, Basler M. “Type VI Secretion System Substrates Are Transferred and Reused among Sister Cells.” Cell. 2016 Sep 22;167(1):99-110.e12. PMID: 27616061

Nelson MB, Chase AB, Martiny JB, Stocker R, Nguyen J, Lloyd K, Oshiro RT, Kearns DB, Schneider JP, Ringel PD, Basler M, Olson CA, Vuong HE, Hsiao EY, Roller BR, Ackermann M, Smillie C, Chien D, Alm E, Jermy AJ. “The Microbial Olympics 2016.” Nat Microbiol. 2016 Jul 26;1(8):16122. PMID: 27573121

Casanova A, Low SH, Emmenlauer M, Conde-Alvarez R, Salcedo SP, Gorvel JP, Dehio C. “Microscopy-based Assays for High-throughput Screening of Host Factors Involved in Brucella Infection of Hela Cells.” J Vis Exp. 2016 Aug 5;(114). PMID: 27584799

Rühl S, Broz P. “The gasdermin-D pore: Executor of pyroptotic cell death.” Oncotarget. 2016 Sep 6;7(36):57481-57482.. PMID: 27557502

Betz C, Lenard A, Belting HG, Affolter M. “Cell behaviors and dynamics during angiogenesis.” Development. 2016 Jul 1;143(13):2249-60. PMID: 27381223

Harms A, Stanger FV, Dehio C. ”Biological Diversity and Molecular Plasticity of FIC Domain Proteins.” Annu Rev Microbiol. 2016 Sep 8;70:341-60.. PMID: 27482742

Gruber AJ, Schmidt R, Gruber AR, Martin G, Ghosh S, Belmadani M, Keller W, Zavolan M. “A comprehensive analysis of 3' end sequencing data sets reveals novel polyadenylation signals and the repressive role of heterogeneous ribonucleoprotein C on cleavage and polyadenylation.” Genome Res. 2016 Aug;26(8):1145-59. PMID: 27382025

Gill JF, Delezie J, Santos G, Handschin C. “PGC-1α expression in murine AgRP neurons regulates food intake and energy balance.” Mol Metab. 2016 Jul;5(7):580-8. PMID: 27408781

Sborgi L, Rühl S, Mulvihill E, Pipercevic J, Heilig R, Stahlberg H, Farady CJ, Müller DJ, Broz P, Hiller S. “GSDMD membrane pore formation constitutes the mechanism of pyroptotic cell death.” EMBO J. 2016 Aug 15;35(16):1766-78.. PMID: 27418190

Hagmann A, Hunkeler M, Stuttfeld E, Maier T. “Hybrid Structure of a Dynamic Single-Chain Carboxylase from Deinococcus radiodurans.” Structure. 2016 Aug 2;24(8):1227-1236. PMID: 27396827

Dick MS, Sborgi L, Rühl S, Hiller S, Broz P. ”ASC filament formation serves as a signal amplification mechanism for inflammasomes.” Nat Commun. 2016 Jun 22;7:11929. PMID: 27329339

Aydogan V, Belting HG, Affolter M. “Mapping the molecular steps of secretory-lysosome-driven tracheal tube fusion.” Nat Cell Biol. 2016 Jun 28;18(7):720-2. PMID: 27350443

Salatino S, Kupr B, Baresic M, van Nimwegen E, Handschin C. “The genomic context and co-recruitment of SP1 affect ERRα co-activation by PGC-1α in muscle cells.” Mol Endocrinol. 2016 May 16;:me20161036. [Epub ahead of print]. PMID: 27182621

Bieli D, Alborelli I, Harmansa S, Matsuda S, Caussinus E, Affolter M. “Development and Application of Functionalized Protein Binders in Multicellular Organisms.” Int Rev Cell Mol Biol. 2016;325:181-213. PMID: 27241221

Haralampieva D, Betzel T, Dinulovic I, Salemi S, Stoelting M, Krämer S, Schibli R, Sulser T, Handschin C, Eberli D, Ametamey SM. “Non-invasive Imaging and Tracking of Engineered Human Muscle Precursor Cells for Skeletal Muscle Tissue Engineering Using Positron Emission Tomography.” J Nucl Med. 2016 May 19;. [Epub ahead of print]. PMID: 27199355

Zwick M, Esposito C, Hellstern M, Seelig A. “Interplay between CFTR Phosphorylation, CFTR-ATPase Activity, and Anion Flux.” J Biol Chem. 2016 May 12;. [Epub ahead of print]. PMID: 27226582

Hunkeler M, Stuttfeld E, Hagmann A, Imseng S, Maier T. ”The dynamic organization of fungal acetyl-CoA carboxylase.” Nat Commun. 2016 Apr 13;7:11196. PMID: 27073141

Guridi M, Kupr B, Romanino K, Lin S, Falcetta D, Tintignac L, Rüegg MA. “Alterations to mTORC1 signaling in the skeletal muscle differentially affect whole-body metabolism.” Skelet Muscle. 2016;6:13. PMID: 27004103

Herbst DA, Jakob RP, Zähringer F, Maier T. “Mycocerosic acid synthase exemplifies the architecture of reducing polyketide synthases.” Nature. 2016 Mar 24;531(7595):533-7. PMID: 26976449

Kälin S, Buser DP, Spiess M. “A fresh look at the function of Rabaptin5 on endosomes.” Small GTPases. 2016 Jan 2;7(1):34-7. PMID: 26940354

Satoh D, Pudenz C, Arber S. “Context-Dependent Gait Choice Elicited by EphA4 Mutation in Lbx1 Spinal Interneurons.” Neuron. 2016 89(5):1046-58.. PMID: 26924434

Svensson K, Albert V, Cardel B, Salatino S, Handschin C. “Skeletal muscle PGC-1α modulates systemic ketone body homeostasis and ameliorates diabetic hyperketonemia in mice.” FASEB J. 2016 May;30(5):1976-86.. PMID: 26849960

Baron AP, von Schubert C, Cubizolles F, Siemeister G, Hitchcock M, Mengel A, Schröder J, Fernández-Montalván A, von Nussbaum F, Mumberg D, Nigg EA. “Probing the catalytic functions of Bub1 kinase using the small molecule inhibitors BAY-320 and BAY-524.” Elife. 2016 Feb 17;5. PMID: 26885717

Stanger FV, Burmann BM, Harms A, Aragão H, Mazur A, Sharpe T, Dehio C, Hiller S, Schirmer T. “Intrinsic regulation of FIC-domain AMP-transferases by oligomerization and automodification.” Proc Natl Acad Sci U S A. 2016 Feb 2;113(5):E529-37. PMID: 26787847

Albert V, Svensson K, Shimobayashi M, Colombi M, Muñoz S, Jimenez V, Handschin C, Bosch F, Hall MN. ”mTORC2 sustains thermogenesis via Akt-induced glucose uptake and glycolysis in brown adipose tissue.” EMBO Mol Med. 2016 Jan 15;8(3):232-46. PMID: 26772600 

Liu X, BoseDasgupta S, Jayachandran R, Studer V, Rühl S, Stiess M, Pieters J. “Activation of the cAMP/protein kinase A signalling pathway by coronin 1 is regulated by cyclin-dependent kinase 5 activity.” FEBS Lett. 2016 Jan;590(2):279-87. PMID: 26823173

Renzi F, Zähringer U, Chandler CE, Ernst RK, Cornelis GR, Ittig SJ. “Modification of the 1-phosphate group during biosynthesis of Capnocytophaga canimorsus lipid A.” Infect Immun. 2015 Dec 7;84(2):550-61. PMID: 26644381

Matsuda S, Harmansa S, Affolter M. “BMP morphogen gradients in flies.” Cytokine Growth Factor Rev. 2016 Feb;27:119-27. PMID: 26684043

Guridi M, Tintignac LA, Lin S, Kupr B, Castets P, Rüegg MA. “Activation of mTORC1 in skeletal muscle regulates whole-body metabolism through FGF21.” Sci Signal. 2015 Nov 10;8(402):ra113. PMID: 26554817

Kupr B, Handschin C. ”Complex Coordination of Cell Plasticity by a PGC-1α-controlled Transcriptional Network in Skeletal Muscle.” Front Physiol. 2015;6:325. PMID: 26617528

Bauer M, Ahrné E, Baron AP, Glatter T, Fava LL, Santamaria A, Nigg EA, Schmidt A. “Assessment of current mass spectrometric workflows for the quantification of low abundant proteins and phosphorylation sites.” Data Brief. 2015 Dec;5:297-304. PMID: 26550600

Harmansa S, Hamaratoglu F, Affolter M, Caussinus E. ”Dpp spreading is required for medial but not for lateral wing disc growth.” Nature. 2015 Nov 19;527(7578):317-22. PMID: 26550827

Reinders A, Hee CS, Ozaki S, Mazur A, Boehm A, Schirmer T, Jenal U. “Expression and Genetic Activation of c-di-GMP specific Phosphodiesterases in Escherichia coli.” J Bacteriol. 2015 Nov 9;198(3):448-62. PMID: 26553851

Basaldella E, Takeoka A, Sigrist M, Arber S. “Multisensory Signaling Shapes Vestibulo-Motor Circuit Specificity.” Cell. 2015 Oct 8;163(2):301-12. PMID: 26451482

Schmich F, Szczurek E, Kreibich S, Dilling S, Andritschke D, Casanova A, Low SH, Eicher S, Muntwiler S, Emmenlauer M, Rämö P, Conde-Alvarez R, von Mering C, Hardt WD, Dehio C, Beerenwinkel N. “gespeR: a statistical model for deconvoluting off-target-confounded RNA interference screens.” Genome Biol. 2015 Oct 7;16:220. PMID: 26445817

Gruss F, Hiller S, Maier T. “Purification and Bicelle Crystallization for Structure Determination of the E. coli Outer Membrane Protein TamA.” Methods Mol Biol. 2015;1329:259-70. PMID: 26427691

Kälin S, Hirschmann DT, Buser DP, Spiess M. “Rabaptin5 is recruited to endosomes by Rab4 and Rabex5 to regulate endosome maturation.” J Cell Sci. 2015; 128(22):4126-37. PMID: 26430212

Borenstein DB, Ringel P, Basler M, Wingreen NS. “Established Microbial Colonies Can Survive Type VI Secretion Assault.” PLoS Comput Biol. 2015 Oct;11(10):e1004520. PMID: 26485125

Aydogan V, Lenard A, Denes AS, Sauteur L, Belting HG, Affolter M. “Endothelial cell division in angiogenic sprouts of differing cellular architecture.” Biol Open. 2015 Sep 14;4(10):1259-69. PMID: 26369932

Kanitz A, Gypas F, Gruber AJ, Gruber AR, Martin G, Zavolan M. ”Comparative assessment of methods for the computational inference of transcript isoform abundance from RNA-seq data.” Genome Biol. 2015 Jul 23;16:150. PMID: 26201343

Arquint C, Gabryjonczyk AM, Imseng S, Böhm R, Sauer E, Hiller S, Nigg EA, Maier T. “STIL binding to Polo-box 3 of PLK4 regulates centriole duplication.” Elife. 2015 Jul 18;4. PMID: 26188084

Albert V, Cornu M, Hall MN. “mTORC1 signaling in Agrp neurons mediates circadian expression of Agrp and NPY but is dispensable for regulation of feeding behavior.” Biochem Biophys Res Commun. 2015 Aug 21;464(2):480-6. PMID: 26159924

Rühl S, Broz P. “Caspase-11 activates a canonical NLRP3 inflammasome by promoting K+ efflux.” Eur J Immunol. 2015 Oct;45(10):2927-36. PMID: 26173909

Poort J, Khan AG, Pachitariu M, Nemri A, Orsolic I, Krupic J, Bauza M, Sahani M, Keller GB, Mrsic-Flogel TD, Hofer SB. “Learning Enhances Sensory and Multiple Non-sensory Representations in Primary Visual Cortex.” Neuron. 2015 Jun 17;86(6):1478-90. PMID: 26051421

Maier T, Clantin B, Gruss F, Dewitte F, Delattre AS, Jacob-Dubuisson F, Hiller S, Villeret V. ”Conserved Omp85 lid-lock structure and substrate recognition in FhaC.” Nat Commun. 2015 Jun 10;6:7452. PMID: 26058369

Albert V, Hall MN. ”Reduced C/EBPβ-LIP translation improves metabolic health.” EMBO Rep. 2015 Aug;16(8):881-2. PMID: 26113367

Ahrné E, Martinez-Segura A, Syed AP, Vina-Vilaseca A, Gruber AJ, Marguerat S, Schmidt A. “Exploiting the multiplexing capabilities of tandem mass tags for high-throughput estimation of cellular protein abundances by mass spectrometry.” Methods. 2015 Sep 1;85:100-7. PMID: 25952948

Svensson K, Schnyder S, Albert V, Cardel B, Quagliata L, Terracciano LM, Handschin C. “Resveratrol and SRT1720 Elicit Differential Effects in Metabolic Organs and Modulates Systemic Parameters Independently of Skeletal Muscle PGC-1α.” J Biol Chem. 2015 Jun 26;290(26):16059-76. PMID: 25987562

Lori C, Ozaki S, Steiner S, Böhm R, Abel S, Dubey BN, Schirmer T, Hiller S, Jenal U. “Cyclic di-GMP acts as a cell cycle oscillator to drive chromosome replication.” Nature. 2015 Jul 9;523(7559):236-9. PMID: 25945741

Heckel E, Boselli F, Roth S, Krudewig A, Belting HG, Charvin G, Vermot J. “Oscillatory Flow Modulates Mechanosensitive klf2a Expression through trpv4 and trpp2 during Heart Valve Development.” Curr Biol. 2015 May 18;25(10):1354-61. PMID: 25959969

Breda J, Rzepiela AJ, Gumienny R, van Nimwegen E, Zavolan M. “Quantifying the strength of miRNA-target interactions.” Methods. 2015 Sep 1;85:90-9. PMID: 25892562

Meunier E, Wallet P, Dreier RF, Costanzo S, Anton L, Rühl S, Dussurgey S, Dick MS, Kistner A, Rigard M, Degrandi D, Pfeffer K, Yamamoto M, Henry T, Broz P. ”Guanylate-binding proteins promote activation of the AIM2 inflammasome during infection with Francisella novicida.” Nat Immunol. 2015 May;16(5):476-84. PMID: 25774716

Lenard A, Daetwyler S, Betz C, Ellertsdottir E, Belting HG, Huisken J, Affolter M. “Endothelial Cell Self-fusion during Vascular Pruning.” PLoS Biol. 2015 Apr;13(4):e1002126.

Burmann BM, Holdbrook DA, Callon M, Bond PJ, Hiller S. “Revisiting the Interaction between the Chaperone Skp and Lipopolysaccharide.” Biophys J. 2015 Mar 24;108(6):1516-26. PMID: 25809264

Brahimi-Horn MC, Lacas-Gervais S, Adaixo R, Ilc K, Rouleau M, Notte A, Dieu M, Michels C, Voeltzel T, Maguer-Satta V, Pelletier J, Ilie M, Hofman P, Manoury B, Schmidt A, Hiller S, Pouysségur J, Mazure NM. “Local mitochondrial-endolysosomal microfusion cleaves the voltage-dependent anion channel 1 to promote survival in hypoxia.” Mol Cell Biol. 2015 May 1;35(9):1491-505. PMID: 25691661

de la Mata M, Gaidatzis D, Vitanescu M, Stadler MB, Wentzel C, Scheiffele P, Filipowicz W, Großhans H. “Potent degradation of neuronal miRNAs induced by highly complementary targets.” EMBO Rep. 2015 Apr;16(4):500-11. PMID: 25724380

Hirschmann DT, Kasper CA, Spiess M. “Quantitative analysis of transferrin cycling by automated fluorescence microscopy.” Methods Mol Biol. 2015;1270:365-78. PMID: 25702129

Phng LK, Gebala V, Bentley K, Philippides A, Wacker A, Mathivet T, Sauteur L, Stanchi F, Belting HG, Affolter M, Gerhardt H. “Formin-mediated actin polymerization at endothelial junctions is required for vessel lumen formation and stabilization.” Dev Cell. 2015 Jan 12;32(1):123-32. PMID: 25584798

Rämö P, Drewek A, Arrieumerlou C, Beerenwinkel N, Ben-Tekaya H, Cardel B, Casanova A, Conde-Alvarez R, Cossart P, Csúcs G, Eicher S, Emmenlauer M, Greber U, Hardt WD, Helenius A, Kasper C, Kaufmann A, Kreibich S, Kühbacher A, Kunszt P, Low SH, Mercer J, Mudrak D, Muntwiler S, Pelkmans L, Pizarro-Cerdá J, Podvinec M, Pujadas E, Rinn B, Rouilly V, Schmich F, Siebourg-Polster J, Snijder B, Stebler M, Studer G, Szczurek E, Truttmann M, von Mering C, Vonderheit A, Yakimovich A, Bühlmann P, Dehio C. “Simultaneous analysis of large-scale RNAi screens for pathogen entry.” BMC Genomics. 2014 Dec 22;15(1):1162. PMID: 25534632

Albert V, Hall MN. ”mTOR signaling in cellular and organismal energetics.” Curr Opin Cell Biol. 2014 Dec 30;33C:55-66. PMID: 25554914

Bauer M, Ahrné E, Baron AP, Glatter T, Fava LL, Santamaria A, Nigg EA, Schmidt A. “Evaluation of Data-Dependent and -Independent Mass Spectrometric Workflows for Sensitive Quantification of Proteins and Phosphorylation Sites.” J Proteome Res. 2014 Dec 5;13(12):5973-88. PMID: 25330945

Gruber AR, Martin G, Müller P, Schmidt A, Gruber AJ, Gumienny R, Mittal N, Jayachandran R, Pieters J, Keller W, van Nimwegen E, Zavolan M. “Global 3' UTR shortening has a limited effect on protein abundance in proliferating T cells.” Nat Commun. 2014 Nov 21;5:5465. PMID: 25413384

Brauchle M, Hansen S, Caussinus E, Lenard A, Ochoa-Espinosa A, Scholz O, Sprecher SG, Plückthun A, Affolter M. “Protein interference applications in cellular and developmental biology using DARPins that recognize GFP and mCherry.” Biol Open. 2014 Nov 21;3(12):1252-61. PMID: 25416061

Santos ME, Braasch I, Boileau N, Meyer BS, Sauteur L, Böhne A, Belting HG, Affolter M, Salzburger W. “The evolution of cichlid fish egg-spots is linked with a cis-regulatory change.” Nat Commun. 2014 Oct 9;5:5149. PMID: 25296686

Sauteur L, Krudewig A, Herwig L, Ehrenfeuchter N, Lenard A, Affolter M, Belting HG. “Cdh5/VE-cadherin Promotes Endothelial Cell Interface Elongation via Cortical Actin Polymerization during Angiogenic Sprouting.” Cell Rep. 2014 Oct 23;9(2):504-13. PMID: 25373898

De Smet F, Tembuyser B, Lenard A, Claes F, Zhang J, Michielsen C, Van Schepdael A, Herbert JM, Bono F, Affolter M, Dewerchin M, Carmeliet P. “Fibroblast Growth Factor Signaling Affects Vascular Outgrowth and Is Required for the Maintenance of Blood Vessel Integrity.” Chem Biol. 2014 Oct 23;21(10):1310-7. PMID: 25200605

Baresic M, Salatino S, Kupr B, van Nimwegen E, Handschin C “Transcriptional network analysis in muscle reveals AP-1 as a partner of PGC-1α in the regulation of the hypoxic gene program.” Mol Cell Biol. 2014 Aug;34(16):2996-3012. PMID: 24912679

Castets P, Lin S, Rion N, Di Fulvio S, Romanino K, Guridi M, Frank S, Tintignac LA, Sinnreich M, Rüegg MA “Sustained activation of mTORC1 in skeletal muscle inhibits constitutive and starvation-induced autophagy and causes a severe, late-onset myopathy.” Cell Metab. 2013 May 7;17(5):731-44. PMID: 23602450

Cornu M, Oppliger W, Albert V, Robitaille AM, Trapani F, Quagliata L, Fuhrer T, Sauer U, Terracciano L, Hall MN “Hepatic mTORC1 controls locomotor activity, body temperature, and lipid metabolism through FGF21.”. Proc Natl Acad Sci U S A. 2014 Aug 12;111(32):11592-9. PMID: 25082895

Gruber AJ, Grandy WA, Balwierz PJ, Dimitrova YA, Pachkov M, Ciaudo C, van Nimwegen E, Zavolan M. “Embryonic stem cell-specific microRNAs contribute to pluripotency by inhibiting regulators of multiple differentiation pathways.” Nucleic Acids Res. 2014 Oct 1;42(14):9313-26. PMID: 25030899

Arquint C, Gabryjonczyk AM, Nigg EA. “Centrosomes as signalling centres.” Philos Trans R Soc Lond B Biol Sci. 2014 Sep 5;369(1650). PMID: 25047618

Vukojevic V, Kolassa IT, Fastenrath M, Gschwind L, Spalek K, Milnik A, Heck A, Vogler C, Wilker S, Demougin P, Peter F, Atucha E, Stetak A, Roozendaal B, Elbert T, Papassotiropoulos A, de Quervain DJ. “Epigenetic Modification of the Glucocorticoid Receptor Gene Is Linked to Traumatic Memory and Post-Traumatic Stress Disorder Risk in Genocide Survivors.” J Neurosci. 2014 Jul 30;34(31):10274-10284. doi: 10.1523/JNEUROSCI.1526-14.2014. PMID: 25080589

Zähringer U, Ittig S, Lindner B, Moll H, Schombel U, Gisch N, Cornelis GR. “NMR Based Structural Analysis of the Complete Rough-type LPS Isolated From Capnocytophaga canimorsus.” J Biol Chem. 2014 Aug 22;289(34):23963-76. PMID: 24993825

Okujava R, Guye P, Lu YY, Mistl C, Polus F, Vayssier-Taussat M, Halin C, Rolink AG, Dehio C. “A Translocated Effector Required for Bartonella Dissemination from Derma to Blood Safeguards Migratory Host Cells from Damage by Co-translocated Effectors.” PLoS Pathog. 2014 Jun;10(6):e1004187. doi: 10.1371/journal.ppat.1004187. PMID: 24945914

Kentner D, Martano G, Callon M, Chiquet P, Brodmann M, Burton O, Wahlander A, Nanni P, Delmotte N, Grossmann J, Limenitakis J, Schlapbach R, Kiefer P, Vorholt JA, Hiller S, Bumann D. “Shigella reroutes host cell central metabolism to obtain high-flux nutrient supply for vigorous intracellular growth.” Proc Natl Acad Sci U S A. 2014 111(27):9929-34. doi: 10.1073/pnas.1406694111. PMID: 24958876

Nigg EA, Cajánek L, Arquint C. “The centrosome duplication cycle in health and disease.” FEBS Lett 2014 588(15):2366-2372. doi: 10.1016/j.febslet.2014.06.030. PMID: 24951839

Biasini M, Bienert S, Waterhouse A, Arnold K, Studer G, Schmidt T, Kiefer F, Cassarino TG, Bertoni M, Bordoli L, Schwede T. “SWISS-MODEL: modelling protein tertiary and quaternary structure using evolutionary information.” Nucleic Acids Res. 2014 42(Web Server issue):W252-8. doi: 10.1093/nar/gku340. PMID: 24782522

Weidner J, Wang C, Prescianotto-Baschong C, Estrada AF, Spang A “The polysome-associated proteins Scp160 and Bfr1 prevent P body formation under normal growth conditions.” J Cell Sci. 2014 May 1;127(Pt 9):1992-2004. doi: 10.1242/jcs.142083. PMID: 24569876

Arnold AS, Gill J, Christe M, Ruiz R, McGuirk S, St-Pierre J, Tabares L, Handschin C. “Morphological and functional remodelling of the neuromuscular junction by skeletal muscle PGC-1alpha.” Nat Commun. 2014 Apr 1;5:3569. doi: 10.1038/ncomms4569. PMID: 24686533

Pieles K, Glatter T, Harms A, Schmidt A, Dehio C. “An experimental strategy for the identification of AMPylation targets from complex protein samples.” Proteomics. 2014 14(9):1048-52. doi: 10.1002/pmic.201300470. PMID: 24677795

Hadziselimovic N, Vukojevic V, Peter F, Milnik A, Fastenrath M, Fenyves BG, Hieber P, Demougin P, Vogler C, de Quervain DJ, Papassotiropoulos A, Stetak A. “Forgetting Is Regulated via Musashi-Mediated Translational Control of the Arp2/3 Complex.” Cell. 2014 Mar 13;156(6):1153-66. doi: 10.1016/j.cell.2014.01.054. PMID: 24630719

Arquint C, Nigg EA. “STIL Microcephaly Mutations Interfere with APC/C-Mediated Degradation and Cause Centriole Amplification.” Curr Biol. 2014 Feb 17;24(4):351-60. doi: 10.1016/j.cub.2013.12.016. PMID: 24485834

Gruber AJ, Zavolan M. “Modulation of epigenetic regulators and cell fate decisions by miRNAs.” Epigenomics. 2013 Dec;5(6):671-83. doi: 10.2217/epi.13.65. PMID: 24283881

Lenard A, Affolter M. “Tugging organs into place.” Dev Cell. 2013 Nov 11;27(3):243-4. doi: 10.1016/j.devcel.2013.10.021. PMID: 24229640

Burmann BM, Wang C, Hiller S. „Conformation and dynamics of the periplasmic membrane-protein-chaperone complexes OmpX-Skp and tOmpA-Skp.” Nat Struct Mol Biol. 2013 Nov;20(11):1265-72. doi: 10.1038/nsmb.2677. PMID: 24077225

Gruss F, Zähringer F, Jakob RP, Burmann BM, Hiller S, Maier T. “The structural basis of autotransporter translocation by TamA.” Nat Struct Mol Biol. 2013 Nov;20(11):1318-20. doi: 10.1038/nsmb.2689. PMID: 24056943

Schmutz C, Ahrne EL, Kasper CA, Tschon T, Sorg I, Dreier RF, Schmidt A, Arrieumerlou C. „Systems-level overview of host protein phosphorylation during Shigella flexneri infection revealed by phosphoproteomics.” Mol Cell Proteomics. 2013 Oct;12(10):2952-68. doi: 10.1074/mcp.M113.029918. PMID: 23828894.

Kochhan E, Lenard A, Ellertsdottir E, Herwig L, Affolter M, Belting HG, Siekmann AF. „Blood Flow Changes Coincide with Cellular Rearrangements during Blood Vessel Pruning in Zebrafish Embryos.” PLoS One. 2013 Oct 11;8(10):e75060. doi: 10.1371/journal.pone.0075060. PMID: 24146748

Bhattacharya I, Drägert K, Albert V, Contassot E, Damjanovic M, Hagiwara A, Zimmerli L, Humar R, Hall MN, Battegay EJ, Haas E. “Rictor in Perivascular Adipose Tissue Controls Vascular Function by Regulating Inflammatory Molecule Expression.” Arterioscler Thromb Vasc Biol. 2013 Sep;33(9):2105-11. doi: 10.1161/ATVBAHA. PMID: 23868942.

Wentzel C, Sommer JE, Nair R, Stiefvater A, Sibarita JB, Scheiffele P. „mSYD1A, a mammalian synapse-defective-1 protein, regulates synaptogenic signaling and vesicle docking.” Neuron. 2013 Jun 19;78(6):1012-23. doi: 10.1016/j.neuron.2013.05.010. PMID: 23791195

Burch P, Binaghi M, Scherer M, Wentzel C, Bossert D, Eberhardt L, Neuburger M, Scheiffele P, Gademann K. „Total synthesis of gelsemiol.“ Chemistry. 2013 Feb 18;19(8):2589-91. doi: 10.1002/chem.201203746. PMID: 23307641

Lenard A, Ellertsdottir E, Herwig L, Krudewig A, Sauteur L, Belting HG, Affolter M. “In Vivo analysis reveals a highly stereotypic morphogenetic pathway of vascular anastomosis.” Dev Cell. 2013 Jun 10;25(5):492-506. doi: 10.1016/j.devcel.2013.05.010. PubMed PMID: 23763948.

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Robitaille AM, Christen S, Shimobayashi M, Cornu M, Fava LL, Moes S, Prescianotto-Baschong C, Sauer U, Jenoe P, Hall MN. “Quantitative phosphoproteomics reveal mTORC1 activates de novo pyrimidine synthesis.” Science. 2013 Mar 15;339(6125):1320-3. doi: 10.1126/science.1228771. PubMed PMID: 23429704.

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Steiner S, Lori C, Boehm A, Jenal U. “Allosteric activation of exopolysaccharide synthesis through cyclic di-GMP-stimulated protein-protein interaction.” EMBO J. 2013 Feb 6;32(3):354-68. doi: 10.1038/emboj.2012.315. PubMed PMID: 23202856

Cornu M, Albert V, Hall MN. “mTOR in aging, metabolism, and cancer.” Curr Opin Genet Dev. 2013 Feb;23(1):53-62. doi: 10.1016/j.gde.2012.12.005. PubMed PMID: 23317514.

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Vukojevic V, Gschwind L, Vogler C, Demougin P, de Quervain DJ, Papassotiropoulos A, Stetak A. “A role for α-adducin (ADD-1) in nematode and human memory.” EMBO J. 2012 Mar 21;31(6):1453-66. doi: 10.1038/emboj.2012.14. PubMed PMID: 22307086.

Arquint C, Sonnen KF, Stierhof YD, Nigg EA. „Cell-cycle-regulated expression of STIL controls centriole number in human cells.” J Cell Sci. 2012 Mar 1;125(Pt 5):1342-52. doi: 10.1242/jcs.099887. PubMed PMID: 22349698.

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Harms A, Dehio C. “Intruders below the radar: molecular pathogenesis of Bartonella spp.” Clin Microbiol Rev. 2012 Jan;25(1):42-78. doi: 10.1128/CMR.05009-11. PubMed PMID: 22232371.

Ittig S, Lindner B, Stenta M, Manfredi P, Zdorovenko E, Knirel YA, dal Peraro M, Cornelis GR, Zähringer U. “The lipopolysaccharide from Capnocytophaga canimorsus reveals an unexpected role of the core-oligosaccharide in MD-2 binding.” PLoS Pathog. 2012;8(5):e1002667. doi: 10.1371/journal.ppat.1002667. PubMed PMID: 22570611.

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Montagner C, Arquint C, Cornelis GR. “Translocators YopB and YopD from Yersinia enterocolitica form a multimeric integral membrane complex in eukaryotic cell membranes. J Bacteriol. 2011 Dec;193(24):6923-8. doi: 10.1128/JB.05555-11. PubMed PMID: 22001511.

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Herwig L, Blum Y, Krudewig A, Ellertsdottir E, Lenard A, Belting HG, Affolter M. “Distinct cellular mechanisms of blood vessel fusion in the zebrafish embryo.” Curr Biol. 2011 Nov 22;21(22):1942-8. doi: 10.1016/j.cub.2011.10.016. PubMed PMID: 22079115.

Manfredi P, Renzi F, Mally M, Sauteur L, Schmaler M, Moes S, Jenö P, Cornelis GR. “The genome and surface proteome of Capnocytophaga canimorsus reveal a key role of glycan foraging systems in host glycoproteins deglycosylation.” Mol Microbiol. 2011 Aug;81(4):1050-60. doi: 10.1111/j.1365-2958.2011.07750.x. PubMed PMID: 21762219.

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Boehm A, Kaiser M, Li H, Spangler C, Kasper CA, Ackermann M, Kaever V, Sourjik V, Roth V, Jenal U. “Second messenger-mediated adjustment of bacterial swimming velocity.” Cell. 2010 Apr 2;141(1):107-16. doi: 10.1016/j.cell.2010.01.018. PubMed PMID: 20303158.

Papadopoulos DK, Vukojevic V, Adachi Y, Terenius L, Rigler R, Gehring WJ. “Function and specificity of synthetic Hox transcription factors in vivo.” Proc Natl Acad Sci U S A. 2010 Mar 2;107(9):4087-92. doi: 10.1073/pnas.0914595107. PubMed PMID: 20147626.

Boehm A, Steiner S, Zaehringer F, Casanova A, Hamburger F, Ritz D, Keck W, Ackermann M, Schirmer T, Jenal U. “Second messenger signalling governs Escherichia coli biofilm induction upon ribosomal stress.” Mol Microbiol. 2009 Jun;72(6):1500-16. doi: 10.1111/j.1365-2958.2009.06739.x. PubMed PMID: 19460094.