Main Content
2020
(2020). Prevention of dsRNA-induced interferon signaling by AGO1x is linked to breast cancer cell proliferation. The EMBO journal, e103922.
(2020). A rare codon-based translational program of cell proliferation. Genome biology, 21 (1), 44.
2019
(2019). Measuring glycolytic flux in single yeast cells with an orthogonal synthetic biosensor. Molecular systems biology, 15 (12), e9071.
(2019). Quorum sensing modulates the formation of virulent Legionella persisters within infected cells. Nature communications, 10 (1), 5216.
(2019). Differential scaling between G1 protein production and cell size dynamics promotes commitment to the cell division cycle in budding yeast. Nature cell biology, 21 (11), 1382-1392.
(2019). Stochastic Protein Alkylation by Antimalarial Peroxides. ACS infectious diseases, 5 (12), 2067-2075.
(2019). Global Ion Suppression Limits the Potential of Mass Spectrometry Based Phosphoproteomics. Journal of proteome research, 18 (1), 493-507.
(2019). Protein synthesis rates and ribosome occupancies reveal determinants of translation elongation rates. Proceedings of the National Academy of Sciences, 116 (30), 15023-15032.
2018
(2018). Deuterium induces a distinctive Escherichia coli proteome that correlates with the reduction in growth rate. Journal of Biological Chemistry, 294 (7), 2279-2292.
(2018). The SKP1-Cullin-F-box E3 ligase βTrCP and CDK2 cooperate to control STIL abundance and centriole number. Open biology, 8 (2), 16.
2017
(2017). The Gcn4 transcription factor reduces protein synthesis capacity and extends yeast lifespan. Nature Communications, 8 (457), 1-12.
(2017). Measurement of in vivo protein binding affinities in a signaling network with mass spectrometry. ACS Synthetic Biology, 6 (7), 1305-1314.
(2017). Paracrine cross-talk between skeletal muscle and macrophages in exercise by PGC-1α-controlled BNP. Scientific Reports, 7, 40789.
(2017). High-throughput identification of C/D box snoRNA targets with CLIP and RiboMeth-seq. Nucleic Acids Research, 45 (5), 2341-2353.
2016
(2016). Bacterial persistence is an active σS stress response to metabolic flux limitation. Molecular Systems Biology, 12 (9), 882.
(2016). Quantitative analysis of human centrosome architecture by targeted proteomics and fluorescence imaging. The EMBO journal, 35 (19), 2152-2166.
(2016). Evaluation and Improvement of Quantification Accuracy in Isobaric Mass Tag-Based Protein Quantification Experiments. Journal of Proteome Research, 15 (8), 2537-47.
(2016). Catechol siderophores repress the pyochelin pathway and activate the enterobactin pathway in Pseudomonas aeruginosa: an opportunity for siderophore-antibiotic conjugates development. Environmental Microbiology, 18 (3), 819-32.
(2016). The quantitative and condition-dependent Escherichia coli proteome. Nature biotechnology, 34 (1), 104-110.
(2016). Synaptic dysfunction, memory deficits and hippocampal atrophy due to ablation of mitochondrial fission in adult forebrain neurons. Cell death and differentiation, 23 (1), 18-28.
2015
(2015). Assessment of current mass spectrometric workflows for the quantification of low abundant proteins and phosphorylation sites. Data in brief, 5, 297-304.
(2015). Protein biogenesis machinery is a driver of replicative aging in yeast. eLife, 4, e08527.
(2015). Comparison of Different Sample Preparation Protocols Reveals Lysis Buffer-Specific Extraction Biases in Gram-Negative Bacteria and Human Cells. Journal of Proteome Research, 14 (11), 4472-85.
(2015). Exploiting the multiplexing capabilities of tandem mass tags for high-throughput estimation of cellular protein abundances by mass spectrometry. Methods, 85, 100-7.
(2015). A Combined Shotgun and Targeted Mass Spectrometry Strategy for Breast Cancer Biomarker Discovery. Journal of Proteome Research, 14 (7), 2807-2818.
(2015). Capture compound mass spectrometry - a powerful tool to identify novel c-di-GMP effector proteins. Journal of visualized experiments, 97 , e51404 (97), e51404.
2014
(2014). Natural genetic variation impacts expression levels of coding, non-coding, and antisense transcripts in fission yeast. Molecular systems biology, 10 (11), 764.
(2014). Evaluation of data-dependent and -independent mass spectrometric workflows for sensitive quantification of proteins and phosphorylation sites. Journal of proteome research, 13 (12), 5973-88.
(2014). Phenotypic variation of salmonella in host tissues delays eradication by antimicrobial chemotherapy. Cell, 158 (4), 722-733.
(2014). Spatial proteomic and phospho-proteomic organization in three prototypical cell migration modes. Proteome science, 12, 23.
(2014). An experimental strategy for the identification of AMPylation targets from complex protein samples. Proteomics, 14 (9), 1048-1052.
(2014). Disparate Impact of Oxidative Host Defenses Determines the Fate of Salmonella during Systemic Infection in Mice. Cell Host & Microbe, 15 (1), 72-83.
2013
(2013). Dual input control : activation of the Bartonella henselae VirB/D4 type IV secretion system by the stringent sigma factor RpoH1 and the BatR/BatS two-component system. Molecular microbiology, 90, H. 4 (4), 756-775.
(2013). Systems-level overview of host protein phosphorylation during Shigella flexneri infection revealed by phosphoproteomics. Molecular & cellular proteomics, 12 (10), 2952-68.
(2013). Critical assessment of proteome-wide label-free absolute abundance estimation strategies. Proteomics, 13 (17), 2567-78.
(2013). Parallel exploitation of diverse host nutrients enhances salmonella virulence. PLoS Pathogens, 9 (4), e1003301.
(2013). Stress induces remodelling of yeast interaction and co-expression networks. Molecular biosystems, 9 (7), 1697-707.
(2013). Extensive mass spectrometry-based analysis of the fission yeast proteome : the Schizosaccharomyces pombe Peptide Atlas. Molecular & cellular proteomics, 12 (6), 1741-51.
(2013). Systematic proteomic analysis identifies beta-site amyloid precursor protein cleaving enzyme 2 and 1 (BACE2 and BACE1) substrates in pancreatic beta-cells. Journal of biological chemistry, 288 (15), 10536-47.
(2013). Glucagon-Induced Acetylation of Foxa2 Regulates Hepatic Lipid Metabolism. Cell metabolism, 17 (3), 436-47.
(2013). A complete mass-spectrometric map of the yeast proteome applied to quantitative trait analysis. Nature, 494 (7436), 266-70.
(2013). Proteomics of Pyrococcus furiosus (Pfu) : Identification of Extracted Proteins by Three Independent Methods. Journal of Proteome Research, 12 (2), 763-70.
(2013). Functioning of a metabolic flux sensor in Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America, 110 (3), 1130-5.
2012
(2012). Quantitative analysis of fission yeast transcriptomes and proteomes in proliferating and quiescent cells. Cell, 151 (3), 671-83.
(2012). Immunity to intracellular Salmonella depends on surface-associated antigens. PLoS Pathogens, 8 (10), e1002966.
(2012). Large-Scale Quantitative Assessment of Different In-Solution Protein Digestion Protocols Reveals Superior Cleavage Efficiency of Tandem Lys-C/Trypsin Proteolysis over Trypsin Digestion. Journal of proteome research, 11 (11), 5145-5156.
(2012). A novel capture compound for the identification and analysis of cyclic di-GMP binding proteins. Journal of Proteomics, 75 (15), 4874-4878.
(2012). Adenylylation control by intra- or intermolecular active-site obstruction in Fic proteins. Nature, 482 (7383), 107-10.
(2012). Comprehensive description of the N-glycoproteome of mouse pancreatic ?-cells and human islets. Journal of Proteome Research, 11 (3), 1598-608.
(2012). Estimation of absolute protein quantities of unlabeled samples by selected reaction monitoring mass spectrometry. Molecular and Cellular Proteomics, 11 (3), M111.013987.
2011
(2011). Modularity and hormone sensitivity of the Drosophila melanogaster insulin receptor/target of rapamycin interaction proteome. Molecular Systems Biology, 7, 547.
(2011). The quantitative proteome of a human cell line. Molecular Systems Biology, 7, 549.
(2011). Bace2 Is a Beta-Cell-Enriched Protease that Regulates Pancreatic Beta-Cell Function and Mass. Cell Metabolism, 14 (3), 365-77.
(2011). IPM: An integrated protein model for false discovery rate estimation and identification in high-throughput proteomics. Journal of Proteomics, 75 (1), 116-21.
(2011). The Plk1-dependent phosphoproteome of the early mitotic spindle. Molecular & cellular proteomics, 10 (1), M110.004457.
(2011). Polycomb purification by in vivo biotinylation tagging reveals cohesin and Trithorax group proteins as interaction partners. Proceedings of the National Academy of Sciences, 108 (14), 5572-7.
(2011). Absolute quantification of microbial proteomes at different states by directed mass spectrometry. Molecular Systems Biology, 7, 510.
(2011). Quantification of mRNA and protein and integration with protein turnover in a bacterium. Molecular Systems Biology, 7, 511.
2010
(2010). ATM-dependent and -independent dynamics of the nuclear phosphoproteome after DNA damage. Science Signaling, 3 (151), rs3.
(2010). Proteomic cell surface phenotyping of differentiating acute myeloid leukemia cells. Blood, 116 (13), e26-34.
2009
(2009). Quantitative peptide and protein profiling by mass spectrometry. Methods in Molecular Biology, 492, 21-38.
(2009). Quantitative interaction proteomics using mass spectrometry. Nature Methods, 6 (3), 203-5.
(2009). Proteome-wide cellular protein concentrations of the human pathogen Leptospira interrogans. Nature, 460 (7256), 762-5.
(2009). Ubiquitin-related modifier Urm1 acts as a sulphur carrier in thiolation of eukaryotic transfer RNA. Nature, 458 (7235), 228-32.
(2009). Protein identification false discovery rates for very large proteomics data sets generated by tandem mass spectrometry. Molecular and Cellular Proteomics, 8 (11), 2405-17.
(2009). Directed mass spectrometry: towards hypothesis-driven proteomics. Current Opinion in Chemical Biology, 13 (5-6), 510-7.
(2009). Analysis of cell surface proteome changes via label-free, quantitative mass spectrometry. Molecular and Cellular Proteomics, 8 (4), 624-38.
(2009). Visual proteomics of the human pathogen Leptospira interrogans. Nature Methods, 6 (11), 817-23.
(2009). Proteome organization in a genome-reduced bacterium. Science, 326 (5957), 1235-40.
(2009). Life-style changes of a halophilic archaeon analyzed by quantitative proteomics. Proteomics, 9 (15), 3843-55.
2008
(2008). Analysis of the peptide profile of milk and its changes during thermal treatment and storage. Journal of Agricultural and Food Chemistry, 56 (9), 2899-906.
(2008). Identification of cross-linked peptides from large sequence databases. Nature methods, 5 (4), 315-8.
(2008). An integrated, directed mass spectrometric approach for in-depth characterization of complex peptide mixtures. Molecular and Cellular Proteomics, 7 (11), 2138-2150.
(2008). The standard protein mix database: a diverse data set to assist in the production of improved Peptide and protein identification software tools. Journal of Proteome Research, 7 (1), 96-103.
(2008). Differential Plasma Glycoproteome of p19 Skin Cancer Mouse Model Using the Corra Label-Free LC-MS Proteomics Platform. Clinical Proteomics, 4 (3-4), 105.
2007
(2007). SuperHirn - a novel tool for high resolution LC-MS-based peptide/protein profiling. Proteomics, 7 (19), 3470-80.
(2007). S6K1-mediated disassembly of mitochondrial URI/PP1gamma complexes activates a negative feedback program that counters S6K1 survival signaling. Molecular Cell, 28 (1), 28-40.
(2007). PhosphoPep-a phosphoproteome resource for systems biology research in Drosophila Kc167 cells. Molecular Systems Biology, 3 (1), 139.
2006
(2006). Quantitative profiling of the membrane proteome in a halophilic archaeon. Molecular and Cellular Proteomics, 5 (9), 1543-58.
(2006). High-accuracy proteome maps of human body fluids. Genome Biology, 7 (11), 242.
(2006). Quantitative analysis of 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced proteome alterations in 5L rat hepatoma cells using isotope-coded protein labels. Proteomics, 6 (8), 2407-2421.
2005
(2005). A novel strategy for quantitative proteomics using isotope-coded protein labels. Proteomics, 5 (1), 4-15.
(2005). Protein stoichiometry of a multiprotein complex, the human spliceosomal U1 small nuclear ribonucleoprotein: absolute quantification using isotope-coded tags and mass spectrometry. Journal of Biological Chemistry, 280 (4), 2536-42.