Research IT

Main Content

2017

Morgado, Leonor; Burmann, Björn M; Sharpe, Timothy; Mazur, Adam; Hiller, Sebastian (2017). The dynamic dimer structure of the chaperone Trigger Factor. Nature communications, 8 (1), 1992.

Benning, Friederike M. C.; Sakiyama, Yusuke; Mazur, Adam; Bukhari, Habib S. T.; Lim, Roderick Y. H.; Maier, Timm (2017). High-Speed Atomic Force Microscopy Visualization of the Dynamics of the Multienzyme Fatty Acid Synthase. ACS Nano, 11 (11), 10852-10859.

2016

Stanger, Frédéric V.; Burmann, Björn M.; Harms, Alexander; Aragão, Hugo; Mazur, Adam; Sharpe, Timothy; Dehio, Christoph; Hiller, Sebastian; Schirmer, Tilman (2016). Intrinsic regulation of FIC-domain AMP-transferases by oligomerization and automodification. Proceedings of the National Academy of Sciences of the United States of America, 113 (5), E529-37.

Hoi Tik Alvin Leung,; Bignucolo, Olivier; Aregger, Regula; Dames, Sonja A.; Mazur, Adam; Berneche, Simon; Grzesiek, Stephan (2016). A Rigorous and Efficient Method To Reweight Very Large Conformational Ensembles Using Average Experimental Data and To Determine Their Relative Information Content. Journal of chemical theory and computation, 12 (1), 383-394.

Swiss Institute of Bioinformatics Members, SIB (2016). The SIB Swiss Institute of Bioinformatics' resources: focus on curated databases. Nucleic acids research, 44 (D1), D27-D37.

Reinders, Alberto; Hee, Chee-Seng; Ozaki, Shogo; Mazur, Adam; Boehm, Alex; Schirmer, Tilman; Jenal, Urs (2016). Expression and Genetic Activation of Cyclic Di-GMP-Specific Phosphodiesterases in Escherichia coli. Journal of Bacteriology, 198 (3), 448-62.

Ravotti, Francesco; Sborgi, Lorenzo; Cadalbert, Riccardo; Huber, Matthias; Mazur, Adam; Broz, Petr; Hiller, Sebastian; Meier, Beat H.; Böckmann, Anja (2016). Sequence-specific solid-state NMR assignments of the mouse ASC PYRIN domain in its filament form. Biomolecular NMR Assignments, 10 (1), 107-15.

He, Lichun; Sharpe, Timothy; Mazur, Adam; Hiller, Sebastian (2016). A molecular mechanism of chaperone-client recognition. Science Advances, 2 (11), e1601625.

Sakiyama, Yusuke; Mazur, Adam; Kapinos, Larisa E.; Lim, Roderick Y. H. (2016). Spatiotemporal dynamics of the nuclear pore complex transport barrier resolved by high-speed atomic force microscopy. Nature Nanotechnology, 11 (8), 719-23.

2015

Sborgi, Lorenzo; Ravotti, Francesco; Dandey, Venkata Prasad; Dick, Mathias S.; Mazur, Adam; Reckel, Sina; Chami, Mohamed; Scherer, Sebastian; Huber, Matthias; Böckmann, Anja; Egelman, Edward H.; Stahlberg, Henning; Broz, Petr; Meier, Beat H.; Hiller, Sebastian (2015). Structure and assembly of the mouse ASC inflammasome by combined NMR spectroscopy and cryo-electron microscopy. Proceedings of the National Academy of Sciences of the United States of America, 112 (43), 13237-42.

2014

Rämö, P; Drewek, A; Arrieumerlou, C; Beerenwinkel, N; Ben-Tekaya, H; Bühlmann, P; Cardel, B; Casanova, A; Conde-Alvarez, R; Cossart, P; Csúcs, G; Eicher, S; Emmenlauer, M; Greber, U; Hardt, W-D; Helenius, A; Kasper, C; Kaufmann. A,; Kreibich, S; Kühbacher, A; Kunszt, P.; Low, SH; Mercer, J; Mudrak, D; Muntwiler, S; Pelkmans, L; Pizarro-Cerdá, J; Podvinec, M; Pujadas, E; Rinn, B; Rouilly, V; Schmich, F; Siebourg, J; Snijder, B; Stebler, M; Studer, G; Szczurek, E; Truttmann, M; von Mering, C; Vonderheit, A; Yakimovich, A; Dehio, C (2014). Simultaneous analysis of large-scale RNAi screens for pathogen entry. BMC Genomics, 15, 1162.

2012

Rouilly, Vincent; Pujadas, Eva; Hullár, Béla; Balázs, Csaba; Kunszt, Peter; Podvinec, Michael (2012). iBRAIN2: automated analysis and data handling for RNAi screens. Studies in health technology and informatics, 175, 205-13.

2010

Podvinec, Michael; Lim, Siew Pheng; Schmidt, Tobias; Scarsi, Marco; Wen, Daying; Sonntag, Louis-Sebastian; Sanschagrin, Paul; Shenkin, Peter S; Schwede, Torsten (2010). Novel Inhibitors of Dengue Virus Methyltransferase : discovery by in vitro-driven virtual screening on a Desktop Computer Grid. Journal of Medicinal Chemistry, 53 (4), 1483-95.

2009

Berman, H. M.; Westbrook, J. D.; Gabanyi, M. J.; Tao, W.; Shah, R.; Kouranov, A.; Schwede, T.; Arnold, K.; Kiefer, F.; Bordoli, L.; Kopp, J.; Podvinec, M.; Adams, P. D.; Carter, L. G.; Minor, W.; Nair, R.; Baer, J. L. (2009). The protein structure initiative structural genomics knowledgebase. Nucleic Acids Research, 37 (1Supplement), D365-D368.

Arnold, K.; Kiefer, F.; Kopp, J.; Battey, J. N.; Podvinec, M.; Westbrook, J. D.; Berman, H. M.; Bordoli, L.; Schwede, T. (2009). The protein model portal. Journal of structural and functional genomics, 10 (1), 1-8.

2008

Podvinec, M.; Schwede, T.; Peitsch, M. C.: Docking for neglected diseases as community efforts, in: Schwede T,; Peitsch MC, (Ed.). (2008). Computational structural biology, Singapore: World Scientific Publishing, S.683-704.

Moehren, Udo; Denayer, Sarah; Podvinec, Michael; Verrijdt, Guy; Claessens, Frank (2008). Identification of androgen-selective androgen-response elements in the human aquaporin-5 and Rad9 genes. The Biochemical Journal, 411 (3), 679-86.

2007

Zosso, D; Podvinec, M; Müller, M; Aebersold, R; Peitsch, M C; Schwede, T (2007). Tandem mass spectrometry protein identification on a PC grid. Studies in health technology and informatics, 126, 3-12.

Scarsi, Marco; Podvinec, Michael; Roth, Adrian; Hug, Hubert; Kersten, Sander; Albrecht, Hugo; Schwede, Torsten; Meyer, Urs A; Rücker, Christoph (2007). Sulfonylureas and glinides exhibit peroxisome proliferator-activated receptor gamma activity : a combined virtual screening and biological assay approach. Molecular pharmacology, 71 (2), 398-406.

Zosso, D.; Arnold, K.; Schwede, T.; Podvinec, M.: SWISS-TANDEM : a Web-based workspace for MS/MS protein identification on PC grid, in: Kokol, P; Podgorelec, V; MiceticTurk, D; Zorman, M; Verlic, M (Ed.). (2007). Twentieth IEEE international symposium on computer-based medical systems, Los Alamitos, Calif.: IEEE Computer Society, CBMS 2007.

2006

Podvinec, M.; Maffioletti, S.; Kunszt, P.; Arnold, K.; Cerutti, L.; Nyffeler, B.; Schlapbach, R.; Turker, C.; Stockinger, H.; Thomas, A. J.; Peitsch, M. C.; Schwede, T.: The SwissBioGrid Project : objectives, preliminary results and lessons learnede-Science 2006 : 2nd IEEE International Conference on e-Science and Grid Computing, Los Alamitos, Calif.: IEEE Computer Society, e-Science 2006, 148.

Podvinec, Michael; Meyer, Urs A (2006). Prediction of cis-regulatory elements for drug-activated transcription factors in the regulation of drug-metabolising enzymes and drug transporters. Expert Opinion on Drug Metabolism & Toxicology, 2 (3), 367-79.

2005

Gnerre, C.; Schuster, G. U.; Roth, A.; Handschin, C.; Johansson, L.; Looser, R.; Parini, P.; Podvinec, M.; Robertsson, K.; Gustafsson, J. -A.; Meyer, U. A. (2005). LXR deficiency and cholesterol feeding affect the expression and phenobarbital-mediated induction of cytochromes P450 in mouse liver. Journal of Lipid Research, 46 (8), 1633-42.

2004

Podvinec, M.; Handschin, C.; Looser, R.; Meyer, U. A. (2004). Identification of the xenosensors regulating human 5-aminolevulinate synthase. Proceedings of the National Academy of Sciences of the United States of America, 101 (24), 9127-32.

Handschin, Christoph; Blättler, Sharon; Roth, Adrian; Looser, Renate; Oscarson, Mikael; Kaufmann, Michel R; Podvinec, Michael; Gnerre, Carmela; Meyer, Urs A (2004). The evolution of drug-activated nuclear receptors : one ancestral gene diverged into two xenosensor genes in mammals. Nuclear Receptor, 2 (1), 7.

Schreiber, Sylvia N; Emter, Roger; Hock, M Benjamin; Knutti, Darko; Cardenas, Jessica; Podvinec, Michael; Oakeley, Edward J; Kralli, Anastasia (2004). The estrogen-related receptor α (ERRα) functions in PPARγ coactivator 1α (PGC-1α)-induced mitochondrial biogenesis. Proceedings of the National Academy of Sciences of the United States of America, 101 (17), 6472-7.

2003

Sanyal, S.; Handschin, C.; Podvinec, M.; Song, K. -H.; Kim, H. -J.; Kim, J. -Y.; Seo, Y. -W.; Kim, S. -A.; Kwon, H. -B.; Lee, K.; Kim, W. -S.; Meyer, U. A.; Choi, H. -S. (2003). Molecular cloning and characterization of chicken orphan nuclear receptor cTR2. General and Comparative Endocrinology, 132 (3), 474-84.

Handschin, Christoph; Podvinec, Michael; Meyer, Urs A. (2003). In silico approaches, and in vitro and in vivo experiments to predict induction of drug metabolism. Drug news & perspectives, 16 (7), 423-434.

2002

Podvinec, Michael; Kaufmann, Michel R; Handschin, Christoph; Meyer, Urs A (2002). NUBIScan, an in silico approach for prediction of nuclear receptor response elements. Molecular endocrinology, 16 (6), 1269-79.

Handschin, C.; Podvinec, M.; Amherd, R.; Looser, R.; Ourlin, J. -C.; Meyer, U. A. (2002). Cholesterol and bile acids regulate xenosensor signaling in drug-mediated induction of cytochromes P450. Journal of Biological Chemistry, 277 (33), 29561-7.

Fraser, David J; Podvinec, Michael; Kaufmann, Michel R; Meyer, Urs A (2002). Drugs mediate the transcriptional activation of the 5-aminolevulinic acid synthase (ALAS1) gene via the chicken xenobiotic-sensing nuclear receptor (CXR). Journal of biological chemistry, 277 (38), 34717-26.

Meyer, Ralf Peter; Podvinec, Michael; Meyer, Urs A (2002). Cytochrome P450 CYP1A1 accumulates in the cytosol of kidney and brain and is activated by heme. Molecular pharmacology, 62 (5), 1061-7.

Kullak-Ublick, Gerd A. (2002). Human organic anion transporting polypeptide 8 promoter is transactivated by the farnesoid X receptor/bile acid receptorw. Gastroenterology, 122 (7), 1954-66.