Program

Friday, March 22nd, 2013

Pharmazentrum, Lecture Hall 1, Klingelbergstrasse 50, CH-­4056 Basel

8:45 – 09:00

Welcome

Session 1 (Chair Stephan Grzesiek)

9:00 – 9:30

Stephen Fesik, Vanderbilt University
Cancer Drug Discovery Using Fragment-Based Methods

9:30 – 10:00

Ad Bax, NIH Bethesda
α-Synuclein, lipids, and Parkinson's disease

10:00 – 10:30

Coffee Break

Session 2 (Chair Sebastian Hiller)
 

10:30 – 11:00

Bob Griffin, MIT Boston
High Frequency Dynamic Nuclear Polarization and
Membrane and Amyloid Protein Structure

11:00 – 11:30

Richard Neutze, University of Gothenburg
Serial crystallography and time-resolved WAXS studies of
membrane proteins at an XFEL

11:30 – 12:00

Mei Hong, Iowa State University
Structural basis for membrane-curvature generation by viral
and antimicrobial peptides: insights from solid-state NMR

12:00 – 12:30

Lukas Tamm, University of Virginia
Structural dynamics of membrane pores and fusion proteins

12:30 – 13:30

Lunch

Session 3 (Chair Timm Maier)

13:30 – 14:00

Sebastian Hiller, Biozentrum
Transport of membrane proteins by molecular chaperones

14:00 – 14:30

Kaspar Locher, ETH Zürich
Structure and mechanism of bacterial ABC transporters

14:30 – 15:00

Kresten Lindorff-Larsen, University of Copenhagen
Doing experiments in the computer—and using NMR to
validate them

15:00 – 15:30

Jens Meiler, Vanderbilt University
Membrane protein structure determination from limited
NMR data

15:30 – 16:00

Coffee Break

Session 4 (Chair Tilman Schirmer)
 

16:00 – 16:30

Thomas Kiefhaber, TU München
Local conformational fluctuations in proteins and peptides
detected by triplet-triplet energy transfer

16:30 – 17:00

Georg Büldt, FZ Jülich
From small molecules to cells

17:00 – 17:30

Stephan Grzesiek, Biozentrum
High-resolution protein thermodynamics

17:30 – 18:00

Anna and Joachim Seelig, Biozentrum

18:00 – 19:00

Apero

19:30

Dinner (Invited Guests)