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SNF-funded PhD position available on the stochastic control of toxin/antitoxin module in the human pathogen Pseudomonas aeruginosa

The Biozentrum of the University of Basel is one of the leading Life Sciences Institutes in the world. It consists of 30 research groups and 500 employees that investigate how molecules and cells create life, spanning the scale from atom to organism. Founded in 1971, the Biozentrum has been the birthplace of many fundamental discoveries in biology and medicine, spawning several Nobel Laureates.

An SNF-funded PhD position is available in the laboratory of Prof. Urs Jenal at the Biozentrum, University of Basel, Switzerland. The mission of the lab is to understand mechanistic principles responsible for virulence and persistence of important human pathogens. Towards these goals, we use a range of cutting-edge techniques including genetic engineering, CRISPRi screens, proteomics, metabolomics, biochemistry and structure-based approaches, microfluidics, tissue engineering, and live cell imaging. The project involves developing and using microfluidic devices, single cell tracking and quantitative image analysis to delineate the stochastic properties of a toxin/antitoxin module and its role in antibiotic tolerance of the human pathogen Pseudomonas aeruginosa.
For more information, see: www.biozentrum.unibas.ch/jenal

Your Profile
We are looking for a highly motivated, rigorous and creative scientist who wants to use quantitative means to address fundamental questions of stochastic control in microbes and how this relates to bacterial physiology and antibiotic resistance. The ideal candidate has a Master’s degree in nanoscience, physics, or in quantitative aspects of microbiology. Applicants with a background in physics, engineering, and/or computer science, and a strong interest in microbiology and infection biology are strongly encouraged to apply. The ability to work both independently and as part of a team is expected, along with good written and oral communication skills in English. 

We offer
The position is funded by a grant of the Swiss National Science Foundation (SNSF) and offers the opportunity to join a multidisciplinary research group including microbiologists and cell biologist with strong expertise in studying molecular aspects of important human pathogens. We provide excellent internal support from various core facilities with expert staff, as well as a strong multi-disciplinary and highly collaborative environment within the Biozentrum and in frame of the NCCR AntiResist (www.nccr-antiresist.ch/en/). 

Basel is an international city with people from 150 nations. Located on the border between Switzerland, Germany and France, it is Europe’s most important Life Science hub. Basel provides a high standard of living and a rich and diverse cultural atmosphere. We embrace diversity and equal opportunity in a serious way. We are committed to building a team that represents a variety of backgrounds, perspectives, and skills. The more inclusive we are, the better our work will be. 

Application / Contact
Please apply online biped2.biozentrum.unibas.ch/apply/phd-jenal-stochastic-control by uploading the following separate PDF documents: 1) Your CV with contact details of two references; 2) A short summary of your past research projects carried out during your studies (diploma thesis, honours project, MSc thesis, etc.). State the rationale and goals of the research, and indicate your own contributions to the results. List publications, if any; 3) A short description of your general scientific interests. What are the scientific questions that you are most passionate about? What brought you to science? 4) Copies of your certificate(s) and diploma(s).

Reviewing of applications will start immediately and continue until the position is filled. The position is available immediately but the starting date can be negotiated. 

For any informal enquiries, please contact Claudia Erbel: claudia.erbel(at)unibasto make life hard for spam bots.ch

We look forward to hearing from you!