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Structure Gallery


C-di-GMP signaling

Phosphodiesterase YkuI
Minasov et al., J. Biol. Chem. (2009)
2w27 In complex with substrate c-di-GMP and calcium

Activated response regulator PleD
Wassmann et al., Structure (2007)
2v0n Activated response regulator PleD in complex with c-di-GMP and GTP-alpha-S

Response regulator PleD
Chan et al., Proc Natl Acad Sci USA (2004)
1w25 Response regulator PleD in complex with c-di-GMP


Porins

NanC porin
Wirth et al., J. Mol. Biol. (2009)
2wjq Structure of NanC from Escherichia coli, purified from the membrane, in a hexagonal crystal form
2wjr Structure of NanC from Escherichia coli, purified from the inclusion bodies, in a rhombohedral crystal form

OmpF porin
Schirmer et al., Nature (1992)
2omf Structure of OmpF from Escherichia coli at 2.4 angstroms resolution
1opf OmpF in a tetragonal crystal form
1mpf Colicin resistant mutant
Site-directed mutant

Osmoporin OmpC
Baslé et al., J Mol Biol (2006)
2j1n Crystal structure of osmoporin OmpC from Escherichia coli
1osm Osmoporin (OmpK36) from Klebsiella pneumoniae

Phosphoporin PhoE
Schirmer et al., Nature (1992)
1pho Crystal structures explain functional properties of two Escherichia coli porins

Maltoporin
Wang et al., J Mol Biol (1997)
1mal Structural basis for sugar translocation through maltoporin channels
1mpm Maltoporin maltose complex
1mpn Maltoporin maltotriose complex
1mpq Maltoporin trehalose complex
1af6 Maltoporin sucrose complex


Sugar permeases

IIB sorbose permease
Orriss et al., J Mol Biol (2003)
1nrz IIB domain of the sorbose permease from Klebsiella pneumoniae
1ble Crystal structure of the IIB subunit of IIBLev from Bacillus subtilis

IIA mannose permease
Nunn et al., J Mol Biol (1996)
1pdo Structure of the IIA domain of the mannose transporter from Escherichia coli


Allergens

Bee venom hyaluronidase
Padavattan et al., J Mol Biol (2007)
2j88 Hyaluronidase in complex with a monoclinical IGG Fab fragment
1fcq Crystal structure (monoclinic) of bee venom hyaluronidase
1fcu Crystal structure (trigonal) of bee venom hyaluronidase
1fcv Crystal structure of hyaluronidase in complex with hyaluronic acid tetramer

Celery allergen API G1
Schirmer et al., J Mol Biol (2005)
2bk0 Crystal structure of the major celery allergen API G 1

Birch Pollen Allergen Bet v 1
Markovic-Housley et al., J Mol Biol (2003)
1fm4 Crystal structure of a hypoallergenic isoform of the major birch pollen allergen Bet v 1


PLP-enzymes

GABA aminotransferase
Storici P et al., J Biol Chem (2004)
1ohv 4-aminobutyrate-aminotransferase from pig
1ohw 4-aminobutyrate-aminotranferase inactivated by gamma-vinyl GABA
1ohy 4-aminobutyrate-aminotransferase inactivated by gamma-ethynyl GABA

Ornithine aminotransferase
Storici et al., J Mol Biol (1999)
1oat Crystal structure of ornithine aminotransferase
2oat Ornithine aminotransferase complexed with 5-fluoromethylornithine
2byj Ornithine aminotransferase mutant Y85I
2byl Structure of ornithine aminotransferase triple mutant Y85I Y55A G320F

Aspartate aminotransferase
Markovic-Housley et al., Eur J Biochem (1996)
1oxo Aspartate aminotransferase, H-asp complex, open conformation
1oxp Aspartate aminotransferase, H-asp complex, closed conformation


Various

Aquaporin-0
Palanivelu et al., J Mol Biol (2006)
2c32 Co-axial association of eye lens aquaporin-0 observed in loosely packed 3D-crystals

Sorbitol dehydrogenase
Philippsen et al., Acta Crystallogr D Biol Crystallogr. (2005)
1k2w Crystal structure of sorbitol dehydrogenase from Rhodobacter sphaeroides

Phosphofructokinase
Schirmer et al., Nature (1990)
6pfk Structure of phosphofructokinase, inhibited T-state

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