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2018

Samanta, Susruta; Bodrenko, Igor; Acosta-Gutiérrez, Silvia; D'Agostino, Tommaso; Pathania, Monisha; Ghai, Ishan; Schleberger, Christian; Bumann, Dirk; Wagner, Richard; Winterhalter, Mathias; van den Berg, Bert; Ceccarelli, Matteo (2018). Getting Drugs through Small Pores: Exploiting the Porins Pathway in Pseudomonas aeruginosa. ACS infectious diseases, epub ahead of print.

Lim, Daejin; Kim, Kwang Soo; Jeong, Jae-Ho; Marques, Oriana; Kim, Hyun-Ju; Song, Miryoung; Lee, Tae-Hoon; Kim, Jae Il; Choi, Hueng-Sik; Min, Jung-Joon; Bumann, Dirk; Muckenthaler, Martina U; Choy, Hyon E (2018). The hepcidin-ferroportin axis controls the iron content of Salmonella-containing vacuoles in macrophages. Nature communications, 9 (1), 2091.

Luscher, Alexandre; Moynié, Lucile; Auguste, Pamela Saint; Bumann, Dirk; Mazza, Lena; Pletzer, Daniel; Naismith, James H; Köhler, Thilo (2018). TonB-Dependent Receptor Repertoire of Pseudomonas aeruginosa for Uptake of Siderophore-Drug Conjugates. Antimicrobial agents and chemotherapy, 62 (6), e00097-18.

2017

Dehio, Christoph; Bumann, Dirk (2017). Editorial overview: Bacterial systems biology. Current opinion in microbiology, 39, viii-xi.

Abellón-Ruiz, Javier; Kaptan, Shreyas S.; Baslé, Arnaud; Claudi, Beatrice; Bumann, Dirk; Kleinekathöfer, Ulrich; van den Berg, Bert (2017). Structural basis for maintenance of bacterial outer membrane lipid asymmetry. Nature Microbiology, 2 (12), 1616-1623.

Bumann, Dirk; Cunrath, Olivier (2017). Heterogeneity of Salmonella-host interactions in infected host tissues. Current Opinion in Microbiology, 39, 57-63.

Wu, Aimin; Tymoszuk, Piotr; Haschka, David; Heeke, Simon; Dichtl, Stefanie; Petzer, Verena; Seifert, Markus; Hilbe, Richard; Sopper, Sieghart; Talasz, Heribert; Bumann, Dirk; Lass-Flörl, Cornelia; Theurl, Igor; Zhang, Keying; Weiss, Guenter (2017). Salmonella utilizes zinc to subvert anti-microbial host defense of macrophages via modulation of NF-κB signaling. Infection and immunity, 85 (12), e00418-17.

Bumann, Dirk; Schothorst, Joep (2017). Intracellular Salmonella metabolism. Cellular Microbiology, 19 (10), e12766.

Schürmann, Nura; Forrer, Pascal; Casse, Olivier; Li, Jiagui; Felmy, Boas; Burgener, Anne-Valérie; Ehrenfeuchter, Nikolaus; Hardt, Wolf-Dietrich; Recher, Mike; Hess, Christoph; Tschan-Plessl, Astrid; Khanna, Nina; Bumann, Dirk (2017). Myeloperoxidase targets oxidative host attacks to Salmonella and prevents collateral tissue damage. Nature Microbiology, 2 (4), 16268.

2016

Trebosc, Vincent; Gartenmann, Sarah; Royet, Kevin; Manfredi, Pablo; Tötzl, Marcus; Schellhorn, Birgit; Pieren, Michel; Tigges, Marcel; Lociuro, Sergio; Sennhenn, Peter C.; Gitzinger, Marc; Bumann, Dirk; Kemmer, Christian (2016). A novel genome editing platform for drug resistant Acinetobacter baumannii revealed an AdeR-unrelated tigecycline resistance mechanism. Antimicrobial Agents and Chemotherapy, 60 (12), 7263-7271.

Freed, Nikki E.; Bumann, Dirk; Silander, Olin K. (2016). Combining Shigella Tn-seq data with gold-standard E. coli gene deletion data suggests rare transitions between essential and non-essential gene functionality. BMC Microbiology, 16 (1), 203.

Gasser, Véronique; Baco, Etienne; Cunrath, Olivier; Saint August, Pamela; Perraud, Quentin; Zill, Nicolas; Schleberger, Christian; Schmidt, Alexander; Paulen, Aurélie; Bumann, Dirk; Mislin, Gaëtan L. A.; Schalk, Isabelle J. (2016). Catechol siderophores repress the pyochelin pathway and activate the enterobactin pathway in Pseudomonas aeruginosa: an opportunity for siderophore-antibiotic conjugates development. Environmental Microbiology, 18 (3), 819-32.

2015

Abu Kwaik, Yousef; Bumann, Dirk (2015). Host delivery of favorite meals for intracellular pathogens. PLoS Pathogens, 11 (6), e1004866.

Bumann, Dirk (2015). Heterogeneous Host-Pathogen Encounters: Act Locally, Think Globally. Cell Host & Microbe, 17 (1), 13-9.

McEwan, David G.; Richter, Benjamin; Claudi, Beatrice; Wigge, Christoph; Wild, Philipp; Farhan, Hesso; McGourty, Kieran; Coxon, Fraser P.; Franz-Wachtel, Mirita; Perdu, Bram; Akutsu, Masato; Habermann, Anja; Kirchof, Anja; Helfrich, Miep H.; Odgren, Paul R.; Van Hul, Wim; Frangakis, Achilleas S.; Rajalingam, Krishnaraj; Macek, Boris; Holden, David W.; Bumann, Dirk; Dikic, Ivan (2015). PLEKHM1 Regulates Salmonella-Containing Vacuole Biogenesis and Infection. Cell Host & Microbe, 17 (1), 58-71.

Martano, Giuseppe; Delmotte, Nathanaël; Kiefer, Patrick; Christen, Philipp; Kentner, David; Bumann, Dirk; Vorholt, Julia A. (2015). Fast sampling method for mammalian cell metabolic analyses using liquid chromatography-mass spectrometry. Nature Protocols, 10 (1), 1-11.

2014

Bumann, Dirk (2014). Identification of protective antigens for vaccination against systemic salmonellosis. Frontiers in Immunology, 5 (381), 381.

Claudi, Beatrice; Spröte, Petra; Chirkova, Anna; Personnic, Nicolas; Zankl, Janine; Schürmann, Nura; Schmidt, Alexander; Bumann, Dirk (2014). Phenotypic variation of salmonella in host tissues delays eradication by antimicrobial chemotherapy. Cell, 158 (4), 722-733.

Kentner, David; Martano, Giuseppe; Callon, Morgane; Chiquet, Petra; Brodmann, Maj; Burton, Olga; Wahlander, Asa; Nanni, Paolo; Delmotte, Nathanaël; Grossmann, Jonas; Limenitakis, Julien; Schlapbach, Ralph; Kiefer, Patrick; Vorholt, Julia A.; Hiller, Sebastian; Bumann, Dirk (2014). Shigella reroutes host cell central metabolism to obtain high-flux nutrient supply for vigorous intracellular growth. Proceedings of the National Academy of Sciences of the United States of America, 111 (27), 9929-34.

Meunier, Etienne; Dick, Mathias S.; Dreier, Roland F.; Schürmann, Nura; Kenzelmann Broz, Daniela; Warming, Søren; Roose-Girma, Merone; Bumann, Dirk; Kayagaki, Nobuhiko; Takeda, Kiyoshi; Yamamoto, Masahiro; Broz, Petr (2014). Caspase-11 activation requires lysis of pathogen-containing vacuoles by IFN-induced GTPases. Nature, 509 (7500), 366-70.

Maze, Alain; Glatter, Timo; Bumann, Dirk (2014). The central metabolism regulator EIIAGlc switches Salmonella from growth arrest to acute virulence through activation of virulence factor secretion. Cell reports, 7 (5), 1426-1433.

Burton, Neil A.; Schürmann, Nura; Casse, Olivier; Steeb, Anne K.; Claudi, Beatrice; Zankl, Janine; Schmidt, Alexander; Bumann, Dirk (2014). Disparate Impact of Oxidative Host Defenses Determines the Fate of Salmonella during Systemic Infection in Mice. Cell Host & Microbe, 15 (1), 72-83.

2013

Steeb, Benjamin; Claudi, Beatrice; Burton, Neil A.; Tienz, Petra; Schmidt, Alexander; Farhan, Hesso; Mazé, Alain; Bumann, Dirk (2013). Parallel exploitation of diverse host nutrients enhances salmonella virulence. PLoS Pathogens, 9 (4), e1003301.

Kwaik, Yousef Abu; Bumann, Dirk (2013). Microbial quest for food in vivo: "Nutritional virulence" as an emerging paradigm. Cellular Microbiology, 15 (6), 882-890.

2012

Mary, Camille; Duek, Paula; Salleron, Lisa; Tienz, Petra; Bumann, Dirk; Bairoch, Amos; Lane, Lydie (2012). Functional Identification of APIP as Human mtnB, a Key Enzyme in the Methionine Salvage Pathway. PLoS ONE, 7 (12), e52877.

Barat, Somedutta; Willer, Yvonne; Rizos, Konstantin; Claudi, Beatrice; Mazé, Alain; Schemmer, Anne K.; Kirchhoff, Dennis; Schmidt, Alexander; Burton, Neil; Bumann, Dirk (2012). Immunity to intracellular Salmonella depends on surface-associated antigens. PLoS Pathogens, 8 (10), e1002966.

Barat, Somedutta; Steeb, Benjamin; Mazé, Alain; Bumann, Dirk (2012). Extensive in vivo resilience of persistent Salmonella. PLoS ONE, 7 (7), e42007.

Willer, Yvonne; Müller, Beatrice; Bumann, Dirk (2012). Intestinal inflammation responds to microbial tissue load independent of pathogen/non-pathogen discrimination. PLoS ONE, 7 (5), e35992.

Schrimpf, Sabine P.; von Mering, Christian; Bendixen, Emøke; Heazlewood, Joshua L.; Bumann, Dirk; Omenn, Gil; Hengartner, Michael O. (2012). The initiative on Model Organism Proteomes (iMOP) Session September 6, 2011, Geneva, Switzerland. Proteomics, 12 (3), 346-350.

Leschner, Sara; Deyneko, Igor V.; Lienenklaus, Stefan; Wolf, Kathrin; Bloecker, Helmut; Bumann, Dirk; Loessner, Holger; Weiss, Siegfried (2012). Identification of tumor-specific Salmonella Typhimurium promoters and their regulatory logic. Nucleic Acids Research, 40 (7), 2984-94.

2011

Stelter, C.; Kappeli, R.; Konig, C.; Krah, A.; Hardt, W. -D.; Stecher, B.; Bumann, D. (2011). Salmonella-Induced Mucosal Lectin RegIIIbeta Kills Competing Gut Microbiota. PLoS ONE, 6 (6), e20749.

Wild, P.; Farhan, H.; McEwan, D. G.; Wagner, S.; Rogov, V. V.; Brady, N. R.; Richter, B.; Korac, J.; Waidmann, O.; Choudhary, C.; Dötsch, V.; Bumann, D.; Dikic, I. (2011). Phosphorylation of the Autophagy Receptor Optineurin Restricts Salmonella Growth. Science, 333 (6039), 228-33.

Hänisch, J.; Kolm, R.; Wozniczka, M.; Bumann, D.; Rottner, K.; Stradal, T. E. B. (2011). Activation of a RhoA/Myosin II-Dependent but Arp2/3 Complex-Independent Pathway Facilitates Salmonella Invasion. Cell Host & Microbe, 9 (4), 273-85.

Crull, K.; Bumann, D.; Weiss, S. (2011). Influence of infection route and virulence factors on colonization of solid tumors by Salmonella enterica serovar Typhimurium. FEMS Immunology and Medical Microbiology, 62 (1), 75-83.

Pawelczyk, S.; Bumann, D.; Abraham, W. R. (2011). Kinetics of carbon sharing in a bacterial consortium revealed by combining stable isotope probing with fluorescence-activated cell sorting. Journal of Applied Microbiology, 110 (4), 1065-73.

Thiele, I.; Hyduke, D. R.; Steeb, B.; Fankam, G.; Allen, D. K.; Bazzani, S.; Charusanti, P.; Chen, F. -C.; Fleming, R. M. T.; Hsiung, C. A.; De Keersmaecker, S. C. J.; Liao, Y. -C.; Marchal, K.; Mo, M. L.; Ozdemir, E.; Raghunathan, A.; Reed, J. L.; Shin, S. -il; Sigurbjornsdottir, S.; Steinmann, J.; Sudarsan, S.; Swainston, N.; Thijs, I. M.; Zengler, K.; Palsson, B. O.; Adkins, J. N.; Bumann, D. (2011). A community effort towards a knowledge-base and mathematical model of the human pathogen Salmonella Typhimurium LT2. BMC Systems Biology, 5 (8), 1-9.

2010

Bumann, Dirk (2010). Pathogen proteomes during infection: a basis for infection research and novel control strategies. Journal of Proteomics, 73 (11), 2267-76.

2009

Bumann, D.; Behre, C.; Behre, K.; Herz, S.; Gewecke, B.; Gessner, J. E.; von Specht, B. U.; Baumann, U. (2009). Systemic, nasal and oral live vaccines against Pseudomonas aeruginosa: a clinical trial of immunogenicity in lower airways of human volunteers. Vaccine, 28 (3), 707-13.

Bumann, Dirk (2009). System-level analysis of Salmonella metabolism during infection. Current Opinion in Microbiology, 12 (5), 559-67.

Hänisch, J.; Ehinger, J.; Ladwein, M.; Rohde, M.; Derivery, E.; Bosse, T.; Steffen, A.; Bumann, D.; Misselwitz, B.; Hardt, W. D.; Gautreau, A.; Stradal, T. E.; Rottner, K. (2009). Molecular dissection of Salmonella-induced membrane ruffling versus invasion. Cellular Microbiology, 12 (1), 84-98.

de Buhr, M. F.; Hedrich, H. J.; Westendorf, A. M.; Obermeier, F.; Hofmann, C.; Zschemisch, N. H.; Buer, J.; Bumann, D.; Goyert, S. M.; Bleich, A. (2009). Analysis of Cd14 as a genetic modifier of experimental inflammatory bowel disease (IBD) in mice. Inflammatory Bowel Diseases, 15 (12), 1824-36.

2008

Bumann, D. (2008). Has nature already identified all useful antibacterial targets?. Current Opinion in Microbiology, 11 (5), 387-392.

Aebischer, T.; Bumann, D.; Epple, H. J.; Metzger, W.; Schneider, T.; Cherepnev, G.; Walduck, A. K.; Kunkel, D.; Moos, V.; Loddenkemper, C.; Jiadze, I.; Panasyuk, M.; Stolte, M.; Graham, D. Y.; Zeitz, M.; Meyer, T. F. (2008). Correlation of T cell response and bacterial clearance in human volunteers challenged with Helicobacter pylori revealed by randomised controlled vaccination with Ty21a-based Salmonella vaccines. Gut, 57 (8), 1065-72.

Bumann, D.; Buss, L. (2008). Nutritional physiology and colony form in Podocoryna carnea (Cnidaria: Hydrozoa). Invertebrate Biology, 127 (4), 368-380.

2007

Thone, F.; Schwanhausser, B.; Becker, D.; Ballmaier, M.; Bumann, D. (2007). FACS-isolation of Salmonella-infected cells with defined bacterial load from mouse spleen. Journal of Microbiological Methods, 71 (3), 220-4.

Kirchhoff, D.; Frentsch, M.; Leclerk, P.; Bumann, D.; Rausch, S.; Hartmann, S.; Thiel, A.; Scheffold, A. (2007). Identification and isolation of murine antigen-reactive T cells according to CD154 expression. European Journal of Immunology, 37 (9), 2370-7.

Halle, S.; Bumann, D.; Herbrand, H.; Willer, Y.; Dahne, S.; Forster, R.; Pabst, O. (2007). Solitary intestinal lymphoid tissue provides a productive port of entry for Salmonella enterica serovar Typhimurium. Infection and Immunity, 75 (4), 1577-85.

Bumann, D.; Valdivia, R. H. (2007). Identification of host-induced pathogen genes by differential fluorescence induction reporter systems. Nature Protocols, 2 (4), 770-7.

2006

Rollenhagen, C.; Bumann, D. (2006). Salmonella enterica highly expressed genes are disease specific. Infection and Immunity, 74 (3), 1649-60.

Becker, D.; Selbach, M.; Rollenhagen, C.; Ballmaier, M.; Meyer, T. F.; Mann, M.; Bumann, D. (2006). Robust Salmonella metabolism limits possibilities for new antimicrobials. Nature, 440 (7082), 303-7.

2005

Sabarth, N.; Hurvitz, R.; Schmidt, M.; Zimny-Arndt, U.; Jungblut, P. R.; Meyer, T. F.; Bumann, D. (2005). Identification of Helicobacter pylori surface proteins by selective proteinase K digestion and antibody phage display. Journal of Microbiological Methods, 62 (3), 345-9.

2004

Rollenhagen, C.; Sorensen, M.; Rizos, K.; Hurvitz, R.; Bumann, D. (2004). Antigen selection based on expression levels during infection facilitates vaccine development for an intracellular pathogen. Proceedings of the National Academy of Sciences of the United States of America, 101 (23), 8739-44.

Metzger, W. G.; Mansouri, E.; Kronawitter, M.; Diescher, S.; Soerensen, M.; Hurwitz, R.; Bumann, D.; Aebischer, T.; Von Specht, B. -U.; Meyer, T. F. (2004). Impact of vector-priming on the immunogenicity of a live recombinant Salmonella enterica serovar typhi Ty21a vaccine expressing urease A and B from Helicobacter pylori in human volunteers. Vaccine, 22 (17-18), 2273-7.

Bumann, D.; Jungblut, P. R.; Meyer, T. F. (2004). Helicobacter pylori vaccine development based on combined subproteome analysis. Proteomics, 4 (10), 2843-8.

Bumann, D.; Habibi, H.; Kan, B.; Schmid, M.; Goosmann, C.; Brinkmann, V.; Meyer, T. F.; Jungblut, P. R. (2004). Lack of stage-specific proteins in coccoid Helicobacter pylori cells. Infection and Immunity, 72 (11), 6738-42.

Arnold, H.; Bumann, D.; Felies, M.; Gewecke, B.; Sorensen, M.; Gessner, J. E.; Freihorst, J.; von Specht, B. U.; Baumann, U. (2004). Enhanced immunogenicity in the murine airway mucosa with an attenuated Salmonella live vaccine expressing OprF-OprI from Pseudomonas aeruginosa. Infection and Immunity, 72 (11), 6546-53.

2003

Sorensen, M.; Lippuner, C.; Kaiser, T.; Misslitz, A.; Aebischer, T.; Bumann, D. (2003). Rapidly maturing red fluorescent protein variants with strongly enhanced brightness in bacteria. FEBS Letters, 552 (2-3), 110-4.

Rizos, K.; Lattemann, C. T.; Bumann, D.; Meyer, T. F.; Aebischer, T. (2003). Autodisplay: efficacious surface exposure of antigenic UreA fragments from Helicobacter pylori in Salmonella vaccine strains. Infection and Immunity, 71 (11), 6320-8.

Daugelat, S.; Kowall, J.; Mattow, J.; Bumann, D.; Winter, R.; Hurwitz, R.; Kaufmann, S. H. E. (2003). The RD1 proteins of Mycobacterium tuberculosis: expression in Mycobacterium smegmatis and biochemical characterization. Microbes and Infection, 5 (12), 1082-1095.

Bumann, D. (2003). T cell receptor-transgenic mouse models for studying cellular immune responses to Salmonella in vivo. FEMS Immunology and Medical Microbiology, 37 (2-3), 105-9.

Bumann, D.; Jungblut, P. R.; Meyer, T. F. (2003). Helicobacter vaccine development based on global approaches. Genome Letters, 2 (1-2), 94-98.

2002

Wendland, M.; Bumann, D. (2002). Optimization of GFP levels for analyzing Salmonella gene expression during an infection. FEBS Letters, 521 (1-3), 105-8.

Sabarth, N.; Lamer, S.; Zimny-Arndt, U.; Jungblut, P. R.; Meyer, T. F.; Bumann, D. (2002). Identification of surface proteins of Helicobacter pylori by selective biotinylation, affinity purification, and two-dimensional gel electrophoresis. Journal of Biological Chemistry, 277 (31), 27896-902.

Sabarth, N.; Hurwitz, R.; Meyer, T. F.; Bumann, D. (2002). Multiparameter selection of Helicobacter pylori antigens identifies two novel antigens with high protective efficacy. Infection and Immunity, 70 (11), 6499-503.

Jungblut, Peter R.; Bumann, Dirk (2002). Immunoproteome of Helicobacter pylori. Methods in Enzymology, 358, 307-316.

Bumann, D.; Holland, P.; Siejak, F.; Koesling, J.; Sabarth, N.; Lamer, S.; Zimny-Arndt, U.; Jungblut, P. R.; Meyer, T. F. (2002). A comparison of murine and human immunoproteomes of Helicobacter pylori validates the preclinical murine infection model for antigen screening. Infection and Immunity, 70 (11), 6494-6498.

Bumann, D.; Aksu, S.; Wendland, M.; Janek, K.; Zimny-Arndt, U.; Sabarth, N.; Meyer, T. F.; Jungblut, P. R. (2002). Proteome analysis of secreted proteins of the gastric pathogen Helicobacter pylori. Infection and Immunity, 70 (7), 3396-403.

Bumann, D. (2002). Examination of Salmonella gene expression in an infected mammalian host using the green fluorescent protein and two-colour flow cytometry. Molecular Microbiology, 43 (5), 1269-83.

2001

Lucas, B.; Bumann, D.; Walduck, A.; Koesling, J.; Develioglu, L.; Meyer, T. F.; Aebischer, T. (2001). Adoptive transfer of CD4+ T cells specific for subunit A of Helicobacter pylori urease reduces H. pylori stomach colonization in mice in the absence of interleukin-4 (IL-4)/IL-13 receptor signaling. Infection and Immunity, 69 (3), 1714-21.

Bumann, D.; Metzger, W. G.; Mansouri, E.; Palme, O.; Wendland, M.; Hurwitz, R.; Haas, G.; Aebischer, T.; von Specht, B. U.; Meyer, T. F. (2001). Safety and immunogenicity of live recombinant Salmonella enterica serovar Typhi Ty21a expressing urease A and B from Helicobacter pylori in human volunteers. Vaccine, 20 (5-6), 845-52.

Bumann, D. (2001). In vivo visualization of bacterial colonization, antigen expression, and specific T-cell induction following oral administration of live recombinant Salmonella enterica serovar Typhimurium. Infection and Immunity, 69 (7), 4618-4626.

Bumann, D. (2001). Regulated antigen expression in live recombinant Salmonella enterica serovar Typhimurium strongly affects colonization capabilities and specific CD4(+)-T-cell responses. Infection and Immunity, 69 (12), 7493-500.

2000

Jungblut, P. R.; Bumann, D.; Haas, G.; Zimny-Arndt, U.; Holland, P.; Lamer, S.; Siejak, F.; Aebischer, A.; Meyer, T. F. (2000). Comparative proteome analysis of Helicobacter pylori. Molecular Microbiology, 36 (3), 710-25.

Bumann, D.; Hueck, C.; Aebischer, T.; Meyer, T. F. (2000). Recombinant live Salmonella spp. for human vaccination against heterologous pathogens. FEMS Immunology and Medical Microbiology, 27 (4), 357-64.

Aebischer, T.; Lucas, B.; Koesling, J.; Bumann, D.; Meyer, T. F. (2000). How CD4(+) T cells may eliminate extracellular gastric Helicobacter?. Journal of Biotechnology, 83 (1-2), 77-84.

1999

Gomez-Duarte, O. G.; Bumann, D.; Meyer, T. F. (1999). The attenuated Salmonella vaccine approach for the control of Helicobacter pylori-related diseases. Vaccine, 17 (13-14), 1667-1673.

1997

Bumann, D.; Puls, G. (1997). The ctenophore Mnemiopsis leidyi has a flow-through system for digestion with three consecutive phases of extracellular digestion. Physiological Zoology, 70 (1), 1-6.

1995

Bumann, D.; Oesterhelt, D. (1995). Destruction of a single chlorophyll is correlated with the photoinhibition of photosystem II with a transiently inactive donor side. Proceedings of the National Academy of Sciences of the United States of America, 92 (26), 12195-9.

1994

Bumann, D.; Oesterhelt, D. (1994). Purification and characterization of oxygen-evolving photosystem II core complexes from the green alga Chlamydomonas reinhardtii. Biochemistry, 33 (36), 10906-10.


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