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2018

Mossmann, Dirk; Park, Sujin; Hall, Michael N (2018). mTOR signalling and cellular metabolism are mutual determinants in cancer. Nature Reviews. Cancer, ahead of print, 1-14.

Martin, S. K.; Fitter, S.; El Khawanky, N.; Grose, R. H.; Walkley, C. R.; Purton, L. E.; Rüegg, M. A.; Hall, M. N.; Gronthos, S.; Zannettino, A. C. W. (2018). mTORC1 plays an important role in osteoblastic regulation of B-lymphopoiesis. Scientific Reports, 8 (1), 14501.

Kessi-Pérez, E. I.; Salinas, F.; Molinet, J.; González, A.; Muñiz, S.; Guillamón, J. M.; Hall, M. N.; Larrondo, L. F.; Martínez, C. (2018). Indirect monitoring of TORC1 signalling pathway reveals molecular diversity among different yeast strains. Yeast, ahead of print.

Mostofa, M. G.; Rahman, M. A.; Koike, N.; Yeasmin, A. M.; Islam, N.; Waliullah, T. Mu.; Hosoyamada, S.; Shimobayashi, M.; Kobayashi, T.; Hall, M. N.; Ushimaru, T. (2018). CLIP and cohibin separate rDNA from nucleolar proteins destined for degradation by nucleophagy. Journal of Cell Biology, 217 (8), 2675-2690.

Hindupur, S. K.; Colombi, M.; Fuhs, S. R.; Matter, M. S.; Guri, Y.; Adam, K.; Cornu, M.; Piscuoglio, S.; Ng, C. K. Y.; Betz, C.; Liko, D.; Quagliata, L.; Moes, S.; Jenoe, P.; Terracciano, L. M.; Heim, M. H.; Hunter, T.; Hall, M. N. (2018). The protein histidine phosphatase LHPP is a tumour suppressor. Nature, 555 (7698), 678-682.

Dimitrakopoulos, C.; Kumar Hindupur, S.; Häfliger, L.; Behr, J.; Montazeri, H.; Hall, M. N.; Beerenwinkel, N. (2018). Network-based integration of multi-omics data for prioritizing cancer genes. Bioinformatics, 34 (14), 2441-2448.

Shimobayashi, M.; Albert, V.; Woelnerhanssen, B.; Frei, I. C.; Weissenberger, D.; Meyer-Gerspach, A. C.; Clement, N.; Moes, S.; Colombi, M.; Meier, J. A.; Swierczynska, M. M.; Jenö, P.; Beglinger, C.; Peterli, R.; Hall, M. N. (2018). Insulin resistance causes inflammation in adipose tissue. Journal of Clinical Investigation, 128 (4), 1538-1550.

Bantug, G. R.; Fischer, M.; Grählert, J.; Balmer, M. L.; Unterstab, G.; Develioglu, L.; Steiner, R.; Zhang, L.; Costa, A. S. H.; Gubser, P. M.; Burgener, A.-V.; Sauder, U.; Löliger, J.; Belle, R.; Dimeloe, S.; Lötscher, J.; Jauch, A.; Recher, M.; Hönger, G.; Hall, M. N.; Romero, P.; Frezza, C.; Hess, C. (2018). Mitochondria-Endoplasmic Reticulum Contact Sites Function as Immunometabolic Hubs that Orchestrate the Rapid Recall Response of Memory CD8+ T Cells. Immunity, 48 (3), 542-555.e6.

Stuttfeld, E.; Aylett, C. H. S.; Imseng, S.; Boehringer, D.; Scaiola, A.; Sauer, E.; Hall, M. N.; Maier, T.; Ban, N. (2018). Architecture of the human mTORC2 core complex. eLife, 7, e33101.

Singer, Jochen; Ruscheweyh, Hans-Joachim; Hofmann, Ariane L; Thurnherr, Thomas; Singer, Franziska; Toussaint, Nora C; Ng, Charlotte K Y; Piscuoglio, Salvatore; Beisel, Christian; Christofori, Gerhard; Dummer, Reinhard; Hall, Michael N; Krek, Wilhelm; Levesque, Mitchell P; Manz, Markus G; Moch, Holger; Papassotiropoulos, Andreas; Stekhoven, Daniel J; Wild, Peter; Wüst, Thomas; Rinn, Bernd; Beerenwinkel, Niko (2018). NGS-pipe: a flexible, easily extendable and highly configurable framework for NGS analysis. Bioinformatics (Oxford, England), 34 (1), 107-108.

2017

Guri, Y.; Colombi, M.; Dazert, E.; Hindupur, S. K.; Roszik, J.; Moes, S.; Jenoe, P.; Heim, M. H.; Riezman, I.; Riezman, H.; Hall, M. N. (2017). mTORC2 Promotes Tumorigenesis via Lipid Synthesis. Cancer Cell, 32 (6), 807-823.e12.

Tang, F.; Zhang, P.; Ye, P.; Lazarski, C. A.; Wu, Q.; Bergin, I. L.; Bender, T. P.; Hall, M. N.; Cui, Y.; Zhang, L.; Jiang, T.; Liu, Y.; Zheng, P. (2017). A population of innate myelolymphoblastoid effector cell expanded by inactivation of mTOR complex 1 in mice. eLife, 6, e32497.

Singer, J.; Ruscheweyh, H.-J.; Hofmann, A. L.; Thurnherr, T.; Singer, F.; Toussaint, N. C.; Ng, C. K. Y.; Piscuoglio, S.; Beisel, C.; Christofori, G.; Dummer, R.; Hall, M. N.; Krek, W.; Levesque, M.; Manz, M. G.; Moch, H.; Papassotiropoulos, A.; Stekhoven, D. J.; Wild, P.; Wüst, T.; Rinn, B.; Beerenwinkel, N. (2017). NGS-pipe: a flexible, easily extendable, and highly configurable framework for NGS analysis. Bioinformatics, 34 (1), 107-108.

Hall, M. N. (2017). An Amazing Turn of Events. Cell, 171 (1), 19-22.

Blandino-Rosano, M.; Barbaresso, R.; Jimenez-Palomares, M.; Bozadjieva, N.; Werneck-de-Castro, J. P.; Hatanaka, M.; Mirmira, R. G.; Sonenberg, N.; Liu, M.; Rüegg, M. A.; Hall, M. N.; Bernal-Mizrachi, E. (2017). Loss of mTORC1 signalling impairs β-cell homeostasis and insulin processing. Nature Communications, 8, 16014.

Benjamin, D.; Hall, M. N. (2017). mTORC1 Controls Synthesis of Its Activator GTP. Cell Reports, 19 (13), 2643-2644.

González, A.; Hall, M. N. (2017). Nutrient sensing and TOR signaling in yeast and mammals. The EMBO Journal, 36 (4), 397-408.

Fitter, S.; Matthews, M. P.; Martin, S. K.; Xie, J.; Ooi, S. S.; Walkley, C. R.; Codrington, J. D.; Rüegg, M. A.; Hall, M. N.; Proud, C. G.; Gronthos, S.; Zannettino, A. C. W. (2017). mTORC1 Plays an Important Role in Skeletal Development by Controlling Preosteoblast Differentiation. Molecular and Cellular Biology, 37 (7), e00668-16.

2016

Benjamin, D.; Colombi, M.; Hindupur, S. K.; Betz, C.; Lane, H. A.; El-Shemerly, M. Y. M.; Lu, M.; Quagliata, L.; Terracciano, L.; Moes, S.; Sharpe, T.; Wodnar-Filipowicz, A.; Moroni, C.; Hall, M. N. (2016). Syrosingopine sensitizes cancer cells to killing by metformin. Science Advances, 2 (12), e1601756.

Ding, X.; Bloch, W.; Iden, S.; Rüegg, M. A.; Hall, M. N.; Leptin, M.; Partridge, L.; Eming, S. A. (2016). mTORC1 and mTORC2 regulate skin morphogenesis and epidermal barrier formation. Nature Communications, 7, 13226.

Guri, Y.; Hall, M. N. (2016). mTOR Signaling Confers Resistance to Targeted Cancer Drugs. Trends in Cancer, 2 (11), 688-697.

Driscoll, D. R.; Karim, S. A.; Sano, M.; Gay, D. M.; Jacob, W.; Yu, J.; Mizukami, Y.; Gopinathan, A.; Jodrell, D. I.; Evans, T. R. J.; Bardeesy, N.; Hall, M. N.; Quattrochi, B. J.; Klimstra, D. S.; Barry, S. T.; Sansom, O. J.; Lewis, B. C.; Morton, J. P. (2016). mTORC2 signaling drives the development and progression of pancreatic cancer. Cancer Research, 76 (23), 6911-6923.

Hall, M. N. (2016). TOR and paradigm change: cell growth is controlled. Molecular Biology of the Cell, 27 (18), 2804-2806.

Swierczynska, M. M.; Hall, M. N. (2016). eIF4A moonlights as an off switch for TORC1. The EMBO Journal, 35 (10), 1013-1014.

Grahammer, F.; Nesterov, V.; Ahmed, A.; Steinhardt, F.; Sandner, L.; Arnold, F.; Cordts, T.; Negrea, S.; Bertog, M.; Rüegg, M. A.; Hall, M. N.; Walz, G.; Korbmacher, C.; Artunc, F.; Huber, T. B. (2016). mTORC2 critically regulates renal potassium handling. Journal of Clinical Investigation, 126 (5), 1773-1782.

Drägert, K.; Bhattacharya, I.; Hall, M. N.; Humar, R.; Battegay, E.; Haas, E. (2016). Basal mTORC2 activity and expression of its components display diurnal variation in mouse perivascular adipose tissue. Biochemical and Biophysical Research Communications, 473 (1), 317-322.

Zhang, L.; Tschumi, B. O.; Lopez-Mejia, I. C.; Oberle, S. G.; Meyer, M.; Samson, G.; Rüegg, M. A.; Hall, M. N.; Fajas, L.; Zehn, D.; Mach, J.-P.; Donda, A.; Romero, P. (2016). Mammalian Target of Rapamycin Complex 2 Controls CD8 T Cell Memory Differentiation in a Foxo1-Dependent Manner. Cell Reports, 14 (5), 1206-1217.

Dazert, E.; Colombi, M.; Boldanova, T.; Moes, S.; Adametz, D.; Quagliata, L.; Roth, V.; Terracciano, L.; Heim, M. H.; Jenoe, P.; Hall, M. N. (2016). Quantitative proteomics and phosphoproteomics on serial tumor biopsies from a sorafenib-treated HCC patient. Proceedings of the National Academy of Sciences of the United States of America, 113 (5), 1381-1386.

Albert, V.; Svensson, K.; Shimobayashi, M.; Colombi, M.; Muñoz, S.; Jimenez, V.; Handschin, C.; Bosch, F.; Hall, M. N. (2016). mTORC2 sustains thermogenesis via Akt-induced glucose uptake and glycolysis in brown adipose tissue. EMBO Molecular Medicine, 8 (3), 232-246.

Aylett, C. H. S.; Sauer, E.; Imseng, S.; Boehringer, D.; Hall, M. N; Ban, N.; Maier, T. (2016). Architecture of human mTOR complex 1. Science, 351 (6268), 48-52.

Shimobayashi, M.; Hall, M. N. (2016). Multiple amino acid sensing inputs to mTORC1. Cell Research, 26 (1), 7-20.

Shende, Pankaj; Xu, Lifen; Morandi, Christian; Pentassuglia, Laura; Heim, Philippe; Lebboukh, Sonia; Berthonneche, Corinne; Pedrazzini, Thierry; Kaufmann, Beat A.; Hall, Michael N.; Rüegg, Markus A.; Brink, Marijke (2016). Cardiac mTOR complex 2 preserves ventricular function in pressure-overload hypertrophy. Cardiovascular Research, 109 (1), 103-14.

Herkert, B.; Kauffmann, A.; Mollé, S.; Schnell, C.; Ferrat, T.; Voshol, H.; Juengert, J.; Erasimus, H.; Marszalek, G.; Kazic-Legueux, M.; Billy, E.; Ruddy, D.; Stump, M.; Guthy, D.; Ristov, M.; Calkins, K.; Maira, S.-M.; Sellers, W. R.; Hofmann, F.; Hall, M. N.; Brachmann, S. M. (2016). Maximizing the Efficacy of MAPK-Targeted Treatment in PTENLOF/BRAFMUT Melanoma through PI3K and IGF1R Inhibition. Cancer Research, 76 (2), 390-402.

Swierczynska, M. M.; Hall, M. N. (2016). mTOR in Metabolic and Endocrine Disorders. , in: Swierczynska, M. M.; Hall, M. N.; , Molecules to Medicine with mTOR. Translating Critical Pathways into Novel Therapeutic Strategies, London:Academic Press, 347-364.

Fonseca, B. D.; Graber, T. E.; Hoang, H.-D.; González, A.; Soukas, A. A.; Hernández, G.; Alain, T.; Swift, S. L.; Weisman, R.; Meyer, C.; Robaglia, C.; Avruch, J.; Hall, M. N. (2016). Evolution of TOR and Translation Control. , in: Fonseca, B. D.; Graber, T. E.; Hoang, H.-D.; González, A.; Soukas, A. A.; Hernández, G.; Alain, T.; Swift, S. L.; Weisman, R.; Meyer, C.; Robaglia, C.; Avruch, J.; Hall, M. N.; , Evolution of the Protein Synthesis Machinery and Its Regulation, Cham:Springer, 327-412.

2015

Aimi, F.; Georgiopoulou, S.; Kalus, I.; Lehner, F.; Hegglin, A.; Limani, P.; Gomes de Lima, V.; Rüegg, M. A.; Hall, M. N.; Lindenblatt, N.; Haas, E.; Battegay, E. J.; Humar, R. (2015). Endothelial Rictor is crucial for midgestational development and sustained and extensive FGF2-induced neovascularization in the adult. Scientific Reports, 5, 17705.

Liko, D.; Hall, M. N. (2015). mTOR in health and in sickness. Journal of Molecular Medicine, 93 (10), 1061-1073.

Cornu, M.; de Caudron de Coquereaumont, G.; Hall, M. N. (2015). mTOR signaling in liver disease. , in: Cornu, M.; de Caudron de Coquereaumont, G.; Hall, M. N.; , Signaling Pathways in Liver Diseases, Oxford UK:John Wiley, 314-325.

Albert, V.; Cornu, M.; Hall, M. N. (2015). mTORC1 signaling in Agrp neurons mediates circadian expression of Agrp and NPY but is dispensable for regulation of feeding behavior. Biochemical and Biophysical Research Communications, 464 (2), 480-486.

Hall, Michael N. (2015). Reduced C/EBPβ-LIP translation improves metabolic health. EMBO reports, 16 (8), 881-2.

Drägert, K.; Bhattacharya, I.; Pellegrini, G.; Seebeck, P.; Azzi, A.; Brown, S. A.; Georgiopoulou, S.; Held, U.; Blyszczuk, P.; Arras, M.; Humar, R.; Hall, M. N.; Battegay, E.; Haas, E. (2015). Deletion of Rictor in Brain and Fat Alters Peripheral Clock Gene Expression and Increases Blood Pressure. Hypertension, 66 (2), 332-339.

Ma, S.; Venkatesh, A.; Langellotto, F.; Le, Y. Z.; Hall, M. N.; Rüegg, M. A.; Punzo, C. (2015). Loss of mTOR signaling affects cone function, cone structure and expression of cone specific proteins without affecting cone survival. Experimental Eye Research, 135, 1-13.

Oliveira, A. P.; Dimopoulos, S.; Busetto, A. G.; Christen, S.; Dechant, R.; Falter, L.; Haghir Chehreghani, M.; Jozefczuk, S.; Ludwig, C.; Rudroff, F.; Schulz, J. C.; González, A.; Soulard, A.; Stracka, D.; Aebersold, R.; Buhmann, J. M.; Hall, M. N.; Peter, M.; Sauer, U.; Stelling, J. (2015). Inferring causal metabolic signals that regulate the dynamic TORC1-dependent transcriptome. Molecular Systems Biology, 11 (4), 802.

Venkatesh, A.; Ma, S.; Le, Y. Z.; Hall, M. N.; Rüegg, M. A.; Punzo, C. (2015). Activated mTORC1 promotes long-term cone survival in retinitis pigmentosa mice. Journal of Clinical Investigation, 125 (4), 1446-1458.

González, A.; Shimobayashi, M.; Eisenberg, T.; Merle, D. A.; Pendl, T.; Hall, M. N.; Moustafa, T. (2015). TORC1 Promotes Phosphorylation of Ribosomal Protein S6 via the AGC Kinase Ypk3 in Saccharomyces cerevisiae. PLoS ONE, 10 (3), e0120250.

Carr, T. D.; Feehan, R. P.; Hall, M. N.; Rüegg, M. A.; Shantz, L. M. (2015). Conditional disruption of rictor demonstrates a direct requirement for mTORC2 in skin tumor development and continued growth of established tumors. Carcinogenesis, 36 (4), 487-497.

Martin, S. K.; Fitter, S.; Dutta, A. K.; Matthews, M. P.; Walkley, C. R.; Hall, M. N.; Rüegg, M. A.; Gronthos, S.; Zannettino, A. C. W. (2015). The differential roles of mTORC1 and mTORC2 in mesenchymal stem cell differentiation. Stem cells, 33 (4), 1359-1365.

Lopez, R. J.; Mosca, B.; Treves, S.; Maj, M.; Bergamelli, L.; Calderon, J. C.; Bentzinger, C. F.; Romanino, K.; Hall, M. N.; Rüegg, M. A.; Delbono, O.; Caputo, C.; Zorzato, F. (2015). Raptor ablation in skeletal muscle decreases Cav1.1 expression and affects the function of the excitation-contraction coupling supramolecular complex. Biochemical Journal, 466 (1), 123-135.

Faller, W. J.; Jackson, T. J.; Knight, J. R. P.; Ridgway, R. A.; Jamieson, T.; Karim, S. A.; Jones, C.; Radulescu, S.; Huels, D. J.; Myant, K. B.; Dudek, K. M.; Casey, H. A.; Scopelliti, A.; Cordero, J. B.; Vidal, M.; Pende, M.; Ryazanov, A. G.; Sonenberg, N.; Meyuhas, O.; Hall, M. N.; Bushell, M.; Willis, A. E.; Sansom, O. J. (2015). mTORC1-mediated translational elongation limits intestinal tumour initiation and growth. Nature, 517 (7535), 497-500.

Hindupur, S. K.; González, A.; Hall, M. N. (2015). The Opposing Actions of Target of Rapamycin and AMP-Activated Protein Kinase in Cell Growth Control. , in: Hindupur, S. K.; González, A.; Hall, M. N.; , Size Control in Biology: From Organelles to Organisms, New York:Cold Spring Harbor Laboratory Press, 221-240.

2014

Albert, V.; Hall, M. N. (2014). mTOR signaling in cellular and organismal energetics. Current Opinion in Cell Biology, 33, 55-66.

Norrmén, C.; Figlia, G.; Lebrun-Julien, F.; Pereira, J. A.; Trötzmüller, M.; Köfeler, H. C.; Rantanen, V.; Wessig, C.; van Deijk, A. F.; Smit, A. B.; Verheijen, M. G.; Rüegg, M. A.; Hall, M. N.; Suter, U. (2014). mTORC1 Controls PNS Myelination along the mTORC1-RXRγ-SREBP-Lipid Biosynthesis Axis in Schwann Cells. Cell Reports, 9 (2), 646-660.

Cornu, M.; Oppliger, W.; Albert, V.; Robitaille, A. M.; Trapani, F.; Quagliata, L.; Fuhrer, T.; Sauer, U.; Terracciano, L.; Hall, M. N. (2014). Hepatic mTORC1 controls locomotor activity, body temperature, and lipid metabolism through FGF21. Proceedings of the National Academy of Sciences of the United States of America, 111 (32), 11592-11599.

Stracka, D.; Jozefczuk, S.; Rudroff, F.; Sauer, U.; Hall, M. N. (2014). Nitrogen Source Activates TOR (Target of Rapamycin) Complex 1 via Glutamine and Independently of Gtr/Rag Proteins. Journal of Biological Chemistry, 289 (36), 25010-25020.

Zhang, L.; Tschumi, B. O.; Corgnac, S.; Rüegg, M. A.; Hall, M. N.; Mach, J.-P.; Romero, P.; Donda, A. (2014). Mammalian target of rapamycin complex 1 orchestrates invariant NKT cell differentiation and effector function. Journal of Immunology, 193 (4), 1759-1765.

Chou, P.-C.; Oh, W. J.; Wu, C.-C.; Moloughney, J.; Rüegg, M. A.; Hall, M. N.; Jacinto, E.; Werlen, G. (2014). Mammalian target of rapamycin complex 2 modulates αβTCR processing and surface expression during thymocyte development. Journal of Immunology, 193 (3), 1162-1170.

Grahammer, F.; Haenisch, N.; Steinhardt, F.; Sander, L.; Roerden, M.; Arnold, F.; Cordts, T.; Wanner, N.; Reichardt, W.; Kerjaschki, D.; Ruegg, M. A.; Hall, M. N.; Moulin, P.; Busch, H.; Boerries, M.; Walz, G.; Artunc, F.; Huber, T. B. (2014). mTORC1 maintains renal tubular homeostasis and is essential in response to ischemic stress. Proceedings of the National Academy of Sciences of the United States of America, 111 (27), E2817-2826.

Lebrun-Julien, F.; Bachmann, L.; Norrmén, C.; Trötzmüller, M.; Köfeler, H.; Rüegg, M. A.; Hall, M. N.; Suter, U. (2014). Balanced mTORC1 activity in oligodendrocytes is required for accurate CNS myelination. Journal of Neuroscience, 34 (25), 8432-8448.

de Cabo, R.; Carmona-Gutierrez, D.; Bernier, M.; Hall, M. N.; Madeo, F. (2014). The Search for Antiaging Interventions: From Elixirs to Fasting Regimens. Cell, 157 (7), 1515-1526.

Umemura, A.; Park, E. J.; Taniguchi, K.; Lee, J. H.; Shalapour, S.; Valasek, M. A.; Aghajan, M.; Nakagawa, H.; Seki, E.; Hall, M. N.; Karin, M. (2014). Liver damage, inflammation, and enhanced tumorigenesis after persistent mTORC1 inhibition. Cell Metabolism, 20 (1), 133-144.

Siamer, S.; Guillas, I.; Shimobayashi, M.; Kunz, C.; Hall, M. N.; Barny, M. A. (2014). Expression of the Bacterial Type III Effector DspA/E in Saccharomyces cerevisiae Down-regulates the Sphingolipid Biosynthetic Pathway Leading to Growth Arrest. Journal of Biological Chemistry, 289 (26), 18466-18477.

Shimobayashi, M.; Hall, M. N. (2014). Making new contacts: the mTOR network in metabolism and signalling crosstalk. Nature Reviews. Molecular Cell Biology, 15 (3), 155-162.

Benjamin, D.; Hall, M. N. (2014). mTORC1: Turning Off Is Just as Important as Turning On. Cell, 156 (4), 627-628.

Chen, J.; Tu, X.; Esen, E.; Joeng, K. S.; Lin, C.; Arbeit, J. M.; Rüegg, M. A.; Hall, M. N.; Ma, L.; Long, F. (2014). WNT7B promotes bone formation in part through mTORC1. PLoS Genetics, 10 (1), e1004145.

Wyder Peters, L.; Molle, K. D.; Thiemeyer, A.; Knopf, A.; Goxe, M.; Guerry, P.; Brodbeck, D.; Colombi, M.; Hall, M. N.; Moroni, C.; Regenass, U. (2014). An Isogenic Cell Panel Identifies Compounds That Inhibit Proliferation of mTOR-Pathway Addicted Cells by Different Mechanisms. Journal of Biomolecular Screening, 19 (1), 131-144.

2013

Betz, C.; Hall, M. N. (2013). Where is mTOR and what is it doing there?. Journal of Cell Biology, 203 (4), 563-574.

Benjamin, D.; Hall, M. N. (2013). TSC on the peroxisome controls mTORC1. Nature Cell Biology, 15 (10), 1135-1136.

Blazek, Matthias; Betz, Charles; Hall, Michael Nip; Reth, Michael; Zengerle, Roland; Meier, Matthias (2013). Proximity Ligation Assay for High Content Profiling of Cell Signaling Pathways on a Microfluidic Chip. Molecular & cellular proteomics, 12 (12), 3898-907.

Thedieck, K.; Holzwarth, B.; Prentzell, M. T.; Boehlke, C.; Kläsener, K.; Ruf, S.; Sonntag, A. G.; Maerz, L.; Grellscheid, S. N.; Kremmer, E.; Nitschke, R.; Kuehn, E. W.; Jonker, J. W.; Groen, A. K.; Reth, M.; Hall, M. N.; Baumeister, R. (2013). Inhibition of mTORC1 by Astrin and Stress Granules Prevents Apoptosis in Cancer Cells. Cell, 154 (4), 859-874.

Bhattacharya, I.; Drägert, K.; Albert, V.; Contassot, E.; Damjanovic, M.; Hagiwara, A.; Zimmerli, L.; Humar, R.; Hall, M. N.; Battegay, E. J.; Haas, E. (2013). Rictor in Perivascular Adipose Tissue Controls Vascular Function by Regulating Inflammatory Molecule Expression. Arteriosclerosis, thrombosis, and vascular biology, 33 (9), 2105-2111.

Sauer, Evelyn; Imseng, Stefan; Maier, Timm; Hall, Michael N (2013). Conserved sequence motifs and the structure of the mTOR kinase domain. Biochemical Society transactions, 41 (4), 889-95.

Saldivia, M.; Barquilla, A.; Bart, J. M.; Diaz-González, R.; Hall, M. N.; Navarro, M. (2013). Target of rapamycin (TOR) kinase in Trypanosoma brucei: an extended family. Biochemical Society Transactions, 41 (4), 934-8.

Betz, C.; Stracka, D.; Prescianotto-Baschong, C.; Frieden, M.; Demaurex, N.; Hall, M. N. (2013). mTOR complex 2-Akt signaling at mitochondria-associated endoplasmic reticulum membranes (MAM) regulates mitochondrial physiology. Proceedings of the National Academy of Sciences of the United States of America, 110 (31), 12526-12534.

Bentzinger, C. F.; Lin, S.; Romanino, K.; Castets, P.; Guridi, M.; Summermatter, S.; Handschin, C.; Tintignac, L. A.; Hall, M. N.; Rüegg, M. A. (2013). Differential response of skeletal muscles to mTORC1 signaling during atrophy and hypertrophy. Skeletal Muscle, 3 (1), 6.

Shortt, J.; Martin, B. P.; Newbold, A.; Hannan, K. M.; Devlin, J. R.; Baker, A. J.; Ralli, R.; Cullinane, C.; Schmitt, C. A.; Reimann, M.; Hall, M. N.; Wall, M.; Hannan, R. D.; Pearson, R. B.; McArthur, G. A.; Johnstone, R. W. (2013). Combined inhibition of PI3K-related DNA-damage response kinases and mTORC1 induces apoptosis in MYC-driven B-cell lymphomas. Blood, 121 (15), 2964-2974.

Robitaille, A. M.; Christen, S.; Shimobayashi, M.; Cornu, M.; Fava, L.; Moes, S.; Prescianotto-Baschong, C.; Sauer, U.; Jenö, P.; Hall, M. N. (2013). Quantitative phosphoproteomics reveal mTORC1 activates de novo pyrimidine synthesis. Science, 339 (6125), 1320-1323.

Shimobayashi, M.; Oppliger, W.; Moes, S.; Jenö, P.; Hall, M. N. (2013). TORC1-regulated protein kinase Npr1 phosphorylates Orm to stimulate complex sphingolipid synthesis. Molecular Biology of the Cell, 24 (6), 870-881.

Cornu, M.; Albert, V.; Hall, M. N. (2013). mTOR in aging, metabolism, and cancer. Current Opinion in Genetics & Development, 23 (1), 53-62.

Hall, M. N. (2013). On mTOR nomenclature. Biochemical Society Transactions, 41 (4), 8817-8888.

2012

Durán, R. V.; Hall, M. N. (2012). Glutaminolysis feeds mTORC1. Cell Cycle, 11 (22), 4107-4108.

Durán, R. V.; Mackenzie, E. D.; Boulahbel, H.; Frezza, C.; Heiserich, L.; Tardito, S.; Bussolati, O.; Rocha, S.; Hall, M. N.; Gottlieb, E. (2012). HIF-independent role of prolyl hydroxylases in the cellular response to amino acids. Oncogene, 32 (38), 4549-4556.

Barquilla, A.; Saldivia, M.; Diaz, R.; Bart, J. -M.; Vidal, I.; Calvo, E.; Hall, M. N.; Navarro, M. (2012). Third target of rapamycin complex negatively regulates development of quiescence in Trypanosoma brucei. Proceedings of the National Academy of Sciences of the United States of America, 109 (36), 14399-14404.

Durán, R. V.; Oppliger, W.; Robitaille, A. M.; Heiserich, L.; Skendaj, R.; Gottlieb, E.; Hall, M. N. (2012). Glutaminolysis activates Rag-mTORC1 signaling. Molecular Cell, 47 (3), 349-358.

Durán, R. V.; Hall, M. N. (2012). Leucyl-tRNA synthetase: double duty in amino acid sensing. Cell Research, 22 (8), 1207-9.

Hagiwara, A.; Cornu, M.; Cybulski, N.; Polak, P.; Betz, C.; Trapani, F.; Terracciano, L.; Heim, M. H.; Rüegg, M. A.; Hall, M. N. (2012). Hepatic mTORC2 activates glycolysis and lipogenesis through akt, glucokinase, and SREBP1c. Cell Metabolism, 15 (5), 725-738.

Liu, Q.; Ren, T.; Fresques, T.; Oppliger, W.; Niles, B. J.; Hur, W.; Sabatini, D. M.; Hall, M. N.; Powers, T.; Gray, N. S. (2012). Selective ATP-competitive inhibitors of TOR suppress rapamycin-insensitive function of TORC2 in Saccharomyces cerevisiae. ACS Chemical Biology, 7 (6), 982-987.

Appenzeller-Herzog, C.; Hall, M. N. (2012). Bidirectional crosstalk between endoplasmic reticulum stress and mTOR signaling. Trends in Cell Biology, 22 (5), 274-282.

Cardon, C. M.; Beck, T.; Hall, M. N.; Rutter, J. (2012). PAS kinase promotes cell survival and growth through activation of Rho1. Science Signaling, 5 (209), ra9.

Robitaille, A. M.; Hall, M. N. (2012). Ramping up mitosis: an AMPKα2-regulated signaling network promotes mitotic progression. Molecular Cell, 45 (1), 8-9.

Durán, R. V.; Hall, M. N. (2012). Regulation of TOR by small GTPases. EMBO Reports, 13 (2), 121-128.

Cybulski, N.; Zinzalla, V.; Hall, M. N. (2012). Inducible raptor and rictor Knockout Mouse Embryonic Fibroblasts. Methods in Molecular Biology, 821, 267-278.

2011

Loewith, R.; Hall, M. N. (2011). Target of Rapamycin (TOR) in nutrient signaling and growth control. Genetics, 189 (4), 1177-1201.

Benjamin, D.; Colombi, M.; Moroni, C.; Hall, M. N. (2011). Rapamycin passes the torch: a new generation of mTOR inhibitors. Nature Reviews. Drug Discovery, 10 (11), 868-880.

Hall, M. N. (2011). Growth grows up COCB themed issue on cell division, growth, and death. Current Opinion in Cell Biology, 23 (6), 705-706.

Dazert, E.; Hall, M. N. (2011). mTOR signaling in disease. Current Opinion in Cell Biology, 23 (6), 744-755.

Chan, J. C.; Hannan, K. M.; Riddell, K.; Ng, P. Y.; Peck, A.; Lee, R. S.; Hung, S.; Astle, M. V.; Bywater, M.; Wall, M.; Poortinga, G.; Jastrzbeski, K.; Sheppard, K. E.; Hemmings, B. A.; Hall, M. N.; Johnstone, R. W.; McArthur, G. A.; Hannan, R. D.; Pearson, R. B. (2011). AKT is a critical regulator of rRNA synthesis and cooperates with c-MYC to control ribosome biogenesis in cancer. Science Signaling, 4 (188), ra56.

Inoki, K.; Mori, H.; Wang, J.; Suzuki, T.; Hong, S.; Yoshida, S.; Blattner, S. M.; Ikenoue, T.; Ruegg, M. A.; Hall, M. N.; Kwiatkowski, D. J.; Rastaldi, M. P.; Huber, T. B.; Kretzler, M.; Holzman, L. B.; Wiggins, R. C.; Guan, K. -L. (2011). mTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice. Journal of Clinical Investigation, 121 (6), 2181-2196.

Gödel, M.; Hartleben, B.; Herbach, N.; Liu, S.; Zschiedrich, S.; Lu, S.; Debreczeni-Mor, A.; Lindenmeyer, M. T.; Rastaldi, M. -P.; Hartleben, G.; Wiech, T.; Fornoni, A.; Nelson, R. G.; Kretzler, M.; Wanke, R.; Pavenstadt, H.; Kerjaschki, D.; Cohen, C. D.; Hall, M. N.; Ruegg, M. A.; Inoki, K.; Walz, G.; Huber, T. B. (2011). Role of mTOR in podocyte function and diabetic nephropathy in humans and mice. Journal of Clinical Investigation, 121 (6), 2197-2209.

Zinzalla, V.; Stracka, D.; Oppliger, W.; Hall, M. N. (2011). Activation of mTORC2 by Association with the Ribosome. Cell, 144 (5), 757-768.

Shende, P.; Plaisance, I.; Morandi, C.; Pellieux, C.; Berthonneche, C.; Zorzato, F.; Krishnan, J.; Lerch, R.; Hall, M. N.; Ruegg, M. A.; Pedrazzini, T.; Brink, M. (2011). Cardiac raptor ablation impairs adaptive hypertrophy, alters metabolic gene expression, and causes heart failure in mice. Circulation, 123 (10), 1073-1082.

Colombi, M.; Molle, K. D.; Benjamin, D.; Rattenbacher-Kiser, K.; Schaefer, C.; Betz, C.; Thiemeyer, A.; Regenass, U.; Hall, M. N.; Moroni, C. (2011). Genome-wide shRNA screen reveals increased mitochondrial dependence upon mTORC2 addiction. Oncogene, 30 (13), 1551-1565.

Hall, M. N. (2011). The history and perspectives of TOR research. Jikken Igaku (Experimental Medicine), 29, 862-864.

2010

Soulard, A.; Cremonesi, A.; Moes, S.; Schutz, F.; Jeno, P.; Hall, M. N. (2010). The rapamycin-sensitive phosphoproteome reveals that TOR controls protein kinase A toward some but not all substrates. Molecular Biology of the Cell, 21 (19), 3475-3486.

Michels, A. A.; Robitaille, A. M.; Buczynski-Ruchonnet, D.; Hodroj, W.; Reina, J. H.; Hall, M. N.; Hernandez, N. (2010). mTORC1 directly phosphorylates and regulates human MAF1. Molecular and Cellular Biology, 30 (15), 3749-3757.

Blagosklonny, M. V.; Campisi, J.; Sinclair, D. A.; Bartke, A.; Blasco, M. A.; Bonner, W. M.; Bohr, V. A.; Brosh, R. M.; Brunet, A.; Depinho, R. A.; Donehower, L. A.; Finch, C. E.; Finkel, T.; Gorospe, M.; Gudkov, A. V.; Hall, M. N.; Hekimi, S.; Helfand, S. L.; Karlseder, J.; Kenyon, C.; Kroemer, G.; Longo, V.; Nussenzweig, A.; Osiewacz, H. D.; Peeper, D. S.; Rando, T. A.; Rudolph, K. L.; Sassone-Corsi, P.; Serrano, M.; Sharpless, N. E.; Skulachev, V. P.; Tilly, J. L.; Tower, J.; Verdin, E.; Vijg, J. (2010). Impact papers on aging in 2009. Aging, 2 (3), 111-121.

Cornu, M.; Hall, M. N. (2010). mTORC1 and mTORC2 in energy homeostasis. , in: Cornu, M.; Hall, M. N.; , Structure, function and regulation of TOR complexes from yeasts to mammals, Amsterdam:Academic Press, 27, 263-278.

Zinzalla, V.; Sturgill, T. W.; Hall, (2010). TOR complexes: composition, structure and phosphorylation. , in: Zinzalla, V.; Sturgill, T. W.; Hall,; , Structure, function and regulation of TOR complexes from yeasts to mammals, Amsterdam:Elsevier, Part A, S.1-20.

2009

Sturgill, T. W.; Hall, M. N. (2009). Activating Mutations in TOR Are in Similar Structures As Oncogenic Mutations in PI3KCalpha. ACS Chemical Biology, 4 (12), 999-1015.

Cybulski, N.; Hall, M. N. (2009). TOR complex 2: a signaling pathway of its own. Trends in Biochemical Sciences, 34 (12), 620-7.

Soulard, A.; Cohen, A.; Hall, M. N. (2009). TOR signaling in invertebrates. Current Opinion in Cell Biology, 21 (6), 825-836.

Blagosklonny, Mikhail V; Hall, Michael N (2009). Growth and aging: a common molecular mechanism. Aging, 1 (4), 357-62.

Polak, P.; Hall, M. N. (2009). mTOR and the control of whole body metabolism. Current Opinion in Cell Biology, 21 (2), 209-218.

Cohen, A.; Hall, M. N. (2009). An amino acid shuffle activates mTORC1. Cell, 136 (3), 399-401.

Patursky-Polischuk, I.; Stolovich-Rain, M.; Hausner-Hanochi, M.; Kasir, J.; Cybulski, N.; Avruch, J.; Rüegg, M. A.; Hall, M. N.; Meyuhas, O. (2009). The TSC-mTOR pathway mediates translational activation of TOP mRNAs by insulin largely in a raptor- or rictor-independent manner. Molecular and Cellular Biology, 29 (3), 640-649.

Cybulski, N.; Polak, P.; Auwerx, J.; Ruegg, M. A.; Hall, M. N. (2009). mTOR complex 2 in adipose tissue negatively controls whole-body growth. Proceedings of the National Academy of Sciences of the United States of America, 106 (24), 9902-9907.

2008

Hall, M. N. (2008). mTOR - what does it do?. Transplantation Proceedings, 40 (10), S5-8.

Sturgill, T. W.; Cohen, A.; Diefenbacher, M.; Trautwein, M.; Martin, D. E.; Hall, M. N. (2008). TOR1 and TOR2 have distinct locations in live cells. Eukaryotic Cell, 7 (10), 1819-1830.

Polak, P.; Cybulski, N.; Feige, J. N.; Auwerx, J.; Rüegg, M. A.; Hall, M. N. (2008). Adipose-Specific Knockout of raptor Results in Lean Mice with Enhanced Mitochondrial Respiration. Cell Metabolism, 8 (5), 399-410.

Jiang, H.; Schiffer, E.; Song, Z.; Wang, J.; Zurbig, P.; Thedieck, K.; Moes, S.; Bantel, H.; Saal, N.; Jantos, J.; Brecht, M.; Jeno, P.; Hall, M. N.; Hager, K.; Manns, M. P.; Hecker, H.; Ganser, A.; Dohner, K.; Bartke, A.; Meissner, C.; Mischak, H.; Ju, Z.; Rudolph, K. L. (2008). Proteins induced by telomere dysfunction and DNA damage represent biomarkers of human aging and disease. Proceedings of the National Academy of Sciences of the United States of America, 105 (32), 11299-11304.

Gander, S.; Bonenfant, D.; Altermatt, P.; Martin, D. E.; Hauri, S.; Moes, S.; Hall, M. N.; Jenoe, P. (2008). Identification of the rapamycin-sensitive phosphorylation sites within the Ser/Thr-rich domain of the yeast Npr1 protein kinase. Rapid Communications in Mass Spectrometry, 22 (23), 3743-3753.

Robitaille, A. M.; Hall, M. N. (2008). mTOR. UCSD Nature Molecular Pages, mp.A000094.

Bentzinger, C. F.; Romanino, K.; Cloëtta, D.; Lin, S.; Mascarenhas, J. B.; Oliveri, F.; Xia, J.; Casanova, E.; Costa, C. F.; Brink, M.; Zorzato, F.; Hall, M. N.; Rüegg, M. A. (2008). Skeletal muscle-specific ablation of raptor, but not of rictor, causes metabolic changes and results in muscle dystrophy. Cell Metabolism, 8 (5), 411-424.

Zinzalla, V.; Hall, M. N. (2008). Signal transduction: linking nutrients to growth. Nature, 454 (7202), 287-8.

2007

Thedieck, K.; Polak, P.; Kim, M. L.; Molle, K. D.; Cohen, A.; Jeno, P.; Arrieumerlou, C.; Hall, M. N. (2007). PRAS40 and PRR5-like protein are new mTOR interactors that regulate apoptosis. PLoS ONE, 2 (11), e1217.

Urban, J.; Soulard, A.; Huber, A.; Lippman, S.; Mukhopadhyay, D.; Deloche, O.; Wanke, V.; Anrather, D.; Ammerer, G.; Riezman, H.; Broach, J. R.; De Virgilio, C.; Hall, M. N.; Loewith, R. (2007). Sch9 is a major target of TORC1 in Saccharomyces cerevisiae. Molecular Cell, 26 (5), 663-674.

Li, W.; Petrimpol, M.; Molle, K. D.; Hall, M. N.; Battegay, E. J.; Humar, R. (2007). Hypoxia-induced endothelial proliferation requires both mTORC1 and mTORC2. Circulation Research, 100 (1), 79-87.

Sturgill, T. W.; Hall, M. N. (2007). Holding back TOR advances mitosis. Nature Cell Biology, 9 (11), 1221-1222.

Soulard, A.; Hall, M. N. (2007). SnapShot: mTOR signaling. Cell, 129 (2), 434-U14.

2006

Wullschleger, S.; Loewith, R.; Hall, M. N. (2006). TOR signaling in growth and metabolism. Cell, 124 (3), 471-484.

Polak, P.; Hall, M. N. (2006). mTORC2 Caught in a SINful Akt. Developmental Cell, 11 (4), 433-434.

Mulet, J. M.; Martin, D. E.; Loewith, R.; Hall, M. N. (2006). Mutual antagonism of target of rapamycin and calcineurin signaling. Journal of Biological Chemistry, 281 (44), 33000-33007.

Wahl, P. R.; Serra, A. L.; Le Hir, M.; Molle, K. D.; Hall, M. N.; Wüthrich, R. P. (2006). Inhibition of mTOR with sirolimus slows disease progression in Han:SPRD rats with autosomal dominant polycystic kidney disease (ADPKD). Nephrology Dialysis Transplantation, 21 (3), 598-604.

Honma, Y.; Kitamura, A.; Shioda, R.; Maruyama, H.; Ozaki, K.; Oda, Y.; Mini, T.; Jenö, P.; Maki, Y.; Yonezawa, K.; Hurt, E.; Ueno, M.; Uritani, M.; Hall, M. N.; Ushimaru, T. (2006). TOR regulates late steps of ribosome maturation in the nucleoplasm via Nog1 in response to nutrients. The EMBO Journal, 25 (16), 3832-3842.

Martin, Dietmar E; Powers, Ted; Hall, Michael N (2006). Regulation of ribosome biogenesis: where is TOR?. Cell Metabolism, 4 (4), 259-60.

2005

Martin, D. E.; Hall, M. N. (2005). The expanding TOR signaling network. Current Opinion in Cell Biology, 17 (2), 158-166.

Dames, S. A.; Mulet, J. M.; Rathgeb-Szabo, K.; Hall, M. N.; Grzesiek, S. (2005). The solution structure of the FATC domain of the protein kinase target of rapamycin suggests a role for redox-dependent structural and cellular stability. Journal of Biological Chemistry, 280 (21), 20558-20564.

Wullschleger, S.; Loewith, R.; Oppliger, W.; Hall, M. N. (2005). Molecular organization of target of rapamycin complex 2. Journal of Biological Chemistry, 280 (35), 30697-30704.

Kamada, Y.; Fujioka, Y.; Suzuki, N. N.; Inagaki, F.; Wullschleger, S.; Loewith, R.; Hall, M. N.; Ohsumi, Y. (2005). TOR2 directly phosphorylates the AGC kinase YPK2 to regulate actin polarization. Molecular and Cellular Biology, 25 (16), 7239-7248.

2004

Martin, D. E.; Demougin, P.; Hall, M. N.; Bellis, M. (2004). Rank difference analysis of microarrays (RDAM), a novel approach to statistical analysis of microarray expression profiling data. BMC Bioinformatics, 5, 148.

Lorberg, A.; Hall, M. N. (2004). TOR - the first 10 years. Current Topics in Microbiology and Immunology, 279, 1-18.

Schmelzle, T.; Beck, T.; Martin, D. E.; Hall, M. N. (2004). Activation of the RAS/cyclic AMP pathway suppresses a TOR deficiency in yeast. Molecular and Cellular Biology, 24 (1), 338-351.

Morales-Johansson, H.; Jenoe, P.; Cooke, F. T.; Hall, M. N. (2004). Negative regulation of phosphatidylinositol 4,5-bisphosphate levels by the INP51-associated proteins TAX4 and IRS4. Journal of Biological Chemistry, 279 (38), 39604-39610.

Jacinto, E.; Loewith, R.; Schmidt, A.; Lin, S.; Rüegg, M. A.; Hall, A.; Hall, M. N. (2004). Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive. Nature Cell Biology, 6 (11), 1122-1128.

Martin, D. E.; Soulard, A.; Hall, M. N. (2004). TOR regulates ribosomal protein gene expression via PKA and the Forkhead transcription factor FHL1. Cell, 119 (7), 969-979.

Burri, L.; Vascotto, K.; Fredersdorf, S.; Tiedt, R.; Hall, M. N.; Lithgow, T. (2004). Zim17: a novel zinc finger protein essential for protein import into mitochondria. Journal of Biological Chemistry, 279 (48), 50243-50249.

Crespo, J. L.; Helliwell, S. B.; Wiederkehr, C.; Demougin, P.; Fowler, B.; Primig, M.; Hall, M. N. (2004). NPR1 kinase and RSP5-BUL1/2 ubiquitin ligase control GLN3-dependent transcription in Saccharomyces cerevisiae. Journal of Biological Chemistry, 279 (36), 37512-37517.

Audhya, A.; Loewith, R.; Parsons, A. B.; Gao, L.; Tabuchi, M.; Zhou, H.; Boone, C.; Hall, M. N.; Emr, S. D. (2004). Genome-wide lethality screen identifies new PI4,5P2 effectors that regulate the actin cytoskeleton. The EMBO Journal, 23 (19), 3747-3757.

Loewith, R.; Hall, M. N. (2004). TOR signaling in yeast: temporal and spatial control of cell growth. , in: Loewith, R.; Hall, M. N.; , Cell growth, New York:Cold Spring Harbor Laboratory Press, S.139-166.

2003

Jacinto, E.; Hall, M. N. (2003). Tor signalling in bugs, brain and brawn. Nature reviews. Molecular Cell Biology, 4 (2), 117-126.

Bonenfant, D.; Schmelzle, T.; Jacinto, E.; Crespo, J. L.; Mini, T.; Hall, M. N.; Jenoe, P. (2003). Quantitation of changes in protein phosphorylation: a simple method based on stable isotope labeling and mass spectrometry. Proceedings of the National Academy of Sciences of the United States of America, 100 (3), 880-885.

Schmelzle, T.; Crespo, J. L.; Hall, M. N. (2003). Translational control by amino acids and energy. , in: Schmelzle, T.; Crespo, J. L.; Hall, M. N.; , Handbook of cell signaling, San Diego, California:Academic Press, Vol. 3, 299-303.

2002

Schmelzle, T.; Helliwell, S. B.; Hall, M. N. (2002). Yeast protein kinases and the RHO1 exchange factor TUS1 are novel components of the cell integrity pathway in yeast. Molecular and Cellular Biology, 22 (5), 1329-1339.

Crespo, J. L.; Powers, T.; Fowler, B.; Hall, M. N. (2002). The TOR-controlled transcription activators GLN3, RTG1, and RTG3 are regulated in response to intracellular levels of glutamine. Proceedings of the National Academy of Sciences of the United States of America, 99 (10), 6784-6789.

Schmidt, A.; Schmelzle, T.; Hall, M. N. (2002). The RHO1-GAPs SAC7, BEM2 and BAG7 control distinct RHO1 functions in Saccharomyces cerevisiae. Molecular Microbiology, 45 (5), 1433-1441.

Desrivieres, S.; Cooke, F. T.; Morales-Johansson, H.; Parker, P. J.; Hall, M. N. (2002). Calmodulin controls organization of the actin cytoskeleton via regulation of phosphatidylinositol (4,5)-bisphosphate synthesis in Saccharomyces cerevisiae. Biochemical Journal, 366 (3), 945-951.

Loewith, R.; Jacinto, E.; Wullschleger, S.; Lorberg, A.; Crespo, J. L.; Bonenfant, D.; Oppliger, W.; Jenoe, P.; Hall, M. N. (2002). Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control. Molecular Cell, 10 (3), 457-468.

Crespo, José L; Hall, Michael N (2002). Elucidating TOR signaling and rapamycin action: lessons from Saccharomyces cerevisiae. Microbiology and molecular biology reviews, 66 (4), 579-91,tableofcontents.

2001

Beck, T.; Delley, P. A.; Hall, M. N. (2001). Control of the actin cytoskeleton by extracellular signals. , in: Beck, T.; Delley, P. A.; Hall, M. N.; , Molecular interactions of actin. Results and Problems in Cell Differentiation, Berlin, Heidelberg:Springer Verlag, 32, 231-262.

Hall, M. N.; Sabatini, D. M. (2001). TOR and Control of Cell Growth. , Cahiers de la Fondation des Treilles, Paris:Centre d'études du bassin méditerranéen, 13.

Crespo, J. L.; Daicho, K.; Ushimaru, T.; Hall, M. N. (2001). The GATA transcription factors GLN3 and GAT1 link TOR to salt stress in Saccharomyces cerevisiae. Journal of Biological Chemistry, 276 (37), 34441-34444.

Friant, S.; Lombardi, R.; Schmelzle, T.; Hall, M. N.; Riezman, H. (2001). Sphingoid base signaling via Pkh kinases is required for endocytosis in yeast. The EMBO Journal, 20 (23), 6783-6792.

Jacinto, E.; Guo, B.; Arndt, K. T.; Schmelzle, T.; Hall, M. N. (2001). TIP41 interacts with TAP42 and negatively regulates the TOR signaling pathway. Molecular cell, 8 (5), 1017-1026.

2000

Schmelzle, T.; Hall, M. N. (2000). TOR, a central controller of cell growth. Cell, 103 (2), 253-262.

Kunz, J.; Loeschmann, A.; Deuter-Reinhard, M.; Hall, M. N. (2000). FAP1, a homologue of human transcription factor NF-X1, competes with rapamycin for binding to FKBP12 in yeast. Molecular Microbiology, 37 (6), 1480-1493.

Kunz, J.; Schneider, U.; Howald, I.; Schmidt, A.; Hall, M. N. (2000). HEAT repeats mediate plasma membrane localization of Tor2p in yeast. Journal of Biological Chemistry, 275 (47), 37011-37020.

Cosentino, G. P.; Schmelzle, T.; Haghighat, A.; Helliwell, S. B.; Hall, M. N.; Sonenberg, N. (2000). Eap1p, a novel eukaryotic translation initiation factor 4E-associated protein in Saccharomyces cerevisiae. Molecular and Cellular Biology, 20 (13), 4604-4613.

Brachat, A.; Liebundguth, N.; Rebischung, C.; Lemire, S.; Scharer, F.; Hoepfner, D.; Demchyshyn, V.; Howald, I.; Dusterhoft, A.; Mostl, D.; Pohlmann, R.; Kotter, P.; Hall, M. N.; Wach, A.; Philippsen, P. (2000). Analysis of deletion phenotypes and GFP fusions of 21 novel Saccharomyces cerevisiae open reading frames. Yeast, 16 (3), 241-253.

1999

Beck, T.; Schmidt, A.; Hall, M. N. (1999). Starvation induces vacuolar targeting and degradation of the tryptophan permease in yeast. The Journal of Cell Biology, 146 (6), 1227-1238.

Delley, P. A.; Hall, M. N. (1999). Cell wall stress depolarizes cell growth via hyperactivation of RHO1. The Journal of Cell Biology, 147 (1), 163-174.

Beck, T.; Hall, M. N. (1999). The TOR signalling pathway controls nuclear localization of nutrient-regulated transcription factors. Nature, 402 (6762), 689-692.

Inagaki, M.; Schmelzle, T.; Yamaguchi, K.; Irie, K.; Hall, M. N.; Matsumoto, K. (1999). PDK1 homologs activate the Pkc1-mitogen-activated protein kinase pathway in yeast. Molecular and Cellular Biology, 19 (12), 8344-8352.

Danaie, P.; Altmann, M.; Hall, M. N.; Trachsel, H.; Helliwell, S. B. (1999). CLN3 expression is sufficient to restore G1-to-S-phase progression in Saccharomyces cerevisiae mutants defective in translation initiation factor eIF4E. Biochemical Journal, 340 (1), 135-141.

1998

Helliwell, S. B.; Howald, I.; Barbet, N.; Hall, M. N. (1998). TOR2 is part of two related signaling pathways coordinating cell growth in Saccharomyces cerevisiae. TOR2 is part of two related signaling pathways coordinating cell growth in Saccharomyces cerevisiae. Genetics, 148 (1), 99-112.

Bickle, M.; Delley, P. A.; Schmidt, A.; Hall, M. N. (1998). Cell wall integrity modulates RHO1 activity via the exchange factor ROM2. The EMBO Journal, 17 (8), 2235-2245.

Desrivieres, S.; Cooke, F. T.; Parker, P. J.; Hall, M. N. (1998). MSS4, a phosphatidylinositol-4-phosphate 5-kinase required for organization of the actin cytoskeleton in Saccharomyces cerevisiae. Journal of Biological Chemistry, 273 (25), 15787-15793.

Schmidt, A.; Beck, T.; Koller, A.; Kunz, J.; Hall, M. N. (1998). The TOR nutrient signalling pathway phosphorylates NPR1 and inhibits turnover of the tryptophan permease. The EMBO Journal, 17 (23), 6924-6931.

Schmidt, A.; Hall, M. N. (1998). Signaling to the actin cytoskeleton. Annual Review of Cell and Developmental Biology, 14, 305-338.

Helliwell, S. B.; Schmidt, A.; Ohya, Y.; Hall, M. N. (1998). The Rho1 effector Pkc1, but not Bni1, mediates signalling from Tor2 to the actin cytoskeleton. Current Biology, 8 (22), 1211-1214.

Cooke, F. T.; Dove, S. K.; McEwen, R. K.; Painter, G.; Holmes, A. B.; Hall, M. N.; Michell, R. H.; Parker, P. J. (1998). The stress-activated phosphatidylinositol 3-phosphate 5-kinase Fab1p is essential for vacuole function in S. cerevisiae. Current Biology, 8 (22), 1219-1222.

1997

Schmidt, A.; Bickle, M.; Beck, T.; Hall, M. N. (1997). The yeast phosphatidylinositol kinase homolog TOR2 activates RHO1 and RHO2 via the exchange factor ROM2. Cell, 88 (4), 531-542.

Thomas, G.; Hall, M. N. (1997). TOR signalling and control of cell growth. Current Opinion in Cell Biology, 9 (6), 782-787.

1996

Hall, M. N. (1996). The TOR signalling pathway and growth control in yeast. Biochemical Society Transactions, 24 (1), 234-239.

Schmidt, A.; Kunz, J.; Hall, M. N. (1996). TOR2 is required for organization of the actin cytoskeleton in yeast. Proceedings of the National Academy of Sciences of the United States of America, 93 (24), 13780-13785.

Koller, A.; Heitman, J.; Hall, M. N. (1996). Regional bivalent-univalent pairing versus trivalent pairing of a trisomic chromosome in Saccharomyces cerevisiae. Regional bivalent-univalent pairing versus trivalent pairing of a trisomic chromosome in Saccharomyces cerevisiae. Genetics, 144 (3), 957-966.

Beretta, L.; Gingras, A. C.; Svitkin, Y. V.; Hall, M. N.; Sonenberg, N. (1996). Rapamycin blocks the phosphorylation of 4E-BP1 and inhibits cap-dependent initiation of translation. The EMBO Journal, 15 (3), 658-64.

Barbet, N. C.; Schneider, U.; Helliwell, S. B.; Stansfield, I.; Tuite, M. F.; Hall, M. N. (1996). TOR controls translation initiation and early G1 progression in yeast. Molecular Biology of the Cell, 7 (1), 25-42.

Hall, M. N. (1996). Yeast cloning book cloning. Trends in Cell Biology, 6 (2), 80.

Hall, M. N. (1996). Drug discovery: rational serendipity. Trends in Biochemical Sciences, 21 (8), 322-323.

1994

Hall, M. N. (1994). Cytosplasm-to-nucleus signaling in yeast: use of immunosuppressive drugs as probes. , in: Hall, M. N.; , Trafic des Protéines chez les Microorganismes, Paris:C.N.R.S. France, 11.

Helliwell, S. B.; Wagner, P.; Kunz, J.; Deuter-Reinhard, M.; Henriquez, R.; Hall, M. N. (1994). TOR1 and TOR2 are structurally and functionally similar but not identical phosphatidylinositol kinase homologues in yeast. Molecular Biology of the Cell, 5 (1), 105-118.

Schmidt, A.; Hall, M. N.; Koller, A. (1994). Two FK506 resistance-conferring genes in Saccharomyces cerevisiae, TAT1 and TAT2, encode amino acid permeases mediating tyrosine and tryptophan uptake. Molecular and Cellular Biology, 14 (10), 6597-6606.

Garcia-Bustos, J. F.; Marini, F.; Stevenson, I.; Frei, C.; Hall, M. N. (1994). PIK1, an essential phosphatidylinositol 4-kinase associated with the yeast nucleus. PIK1, an essential phosphatidylinositol 4-kinase associated with the yeast nucleus. The EMBO Journal, 13 (10), 2352-2361.

Hottiger, T.; De Virgilio, C.; Hall, M. N.; Boller, T.; Wiemken, A. (1994). The role of trehalose synthesis for the acquisition of thermotolerance in yeast: II. Physiological concentrations of trehalose increase the thermal stability of proteins in vitro. European Journal of Biochemistry, 219 (1-2), 187-193.

1993

Tinland, B.; Hall, M. N.; Hohn, B. (1993). Mechanism of T-DNA transfer. , in: Tinland, B.; Hall, M. N.; Hohn, B.; , Advances in Molecular Genetics of Plant-Microbe Interactions, Vol 2, Dordrecht:Kluwer Academic Publ., 14.

Wagner, P.; Hall, M. N. (1993). Nuclear protein transport is functionally conserved between yeast and higher eukaryotes. FEBS Letters, 321 (2-3), 261-266.

Kunz, J.; Hall, M. N. (1993). Cyclosporin A, FK506 and rapamycin: more than just immunosuppression. Trends in Biochemical Sciences, 18 (9), 334-8.

Kunz, J.; Henriquez, R.; Schneider, U.; Deuter-Reinhard, M.; Movva, N. R.; Hall, M. N. (1993). Target of rapamycin in yeast, TOR2, is an essential phosphatidylinositol kinase homolog required for G1 progression. Cell, 73 (3), 585-596.

Heitman, J.; Koller, A.; Kunz, J.; Henriquez, R.; Schmidt, A.; Movva, N. R.; Hall, M. N. (1993). The immunosuppressant FK506 inhibits amino acid import in Saccharomyces cerevisiae. Molecular and Cellular Biology, 13 (8), 5010-5019.

Heitman, J.; Koller, A.; Cardenas, M. E.; Hall, M. N. (1993). Identification of immunosuppressive drug targets in yeast. Methods, 5 (2), 176-187.

1992

Tinland, B.; Koukolíková-Nicola, Z.; Hall, M. N.; Hohn, B. (1992). The T-DNA-linked VirD2 protein contains two distinct functional nuclear localization signals. Proceedings of the National Academy of Sciences of the United States of America, 89 (16), 7442-7446.

Heitman, J.; Movva, N. R.; Hall, M. N. (1992). Proline isomerases at the crossroads of protein folding, signal transduction, and immunosuppression. The New Biologist, 4 (5), 448-460.

Davis, E. S.; Becker, A.; Heitman, J.; Hall, M. N.; Brennan, M. B. (1992). A yeast cyclophilin gene essential for lactate metabolism at high temperature. Proceedings of the National Academy of Sciences of the United States of America, 89 (23), 11169-11173.

1991

Heitman, J.; Movva, N. R.; Hiestand, P. C.; Hall, M. N. (1991). FK 506-binding protein proline rotamase is a target for the immunosuppressive agent FK 506 in Saccharomyces cerevisiae. Proceedings of the National Academy of Sciences of the United States of America, 88 (5), 1948-1952.

Heitman, J.; Movva, N. R.; Hall, M. N. (1991). Targets for cell cycle arrest by the immunosuppressant rapamycin in yeast. Science, 253 (5022), 905-909.

Garcia-Bustos, J. F.; Wagner, P.; Hall, M. N. (1991). Nuclear import substrates compete for a limited number of binding sites: evidence for different classes of yeast nuclear import receptors. Nuclear import substrates compete for a limited number of binding sites: evidence for different classes of yeast nuclear import receptors. Journal of Biological Chemistry, 266 (33), 22303-22306.

Garcia-Bustos, J. F.; Wagner, P.; Hall, M. N. (1991). Yeast cell-free nuclear protein import requires ATP hydrolysis. Experimental Cell Research, 192 (1), 213-219.

Garcia-Bustos, J. F.; Heitman, J.; Hall, M. N. (1991). Nuclear protein localization. Biochimica et Biophysica Acta, 1071 (1), 83-101.

1990

Wagner, P.; Kunz, J.; Koller, A.; Hall, M. N. (1990). Active transport of proteins into the nucleus. FEBS Letters, 275 (1-2), 1-5.

Hall, M. N.; Craik, C.; Hiraoka, Y. (1990). Homeodomain of yeast repressor alpha 2 contains a nuclear localization signal. Proceedings of the National Academy of Sciences of the United States of America, 87 (18), 6954-6958.

1988

Silver, P. A.; Hall, M. N. (1988). Transport of proteins into the nucleus. , in: Silver, P. A.; Hall, M. N.; , Protein Transfer and Organelle Biogenesis, San Diego, California:Academic Press Inc., 749-769.

Hall, M. N.; Fried S. R, (1988). Is nuclear protein localization receptor-mediated?. , in: Hall, M. N.; Fried S. R,; , Molecular Biology of Intracellular Protein Sorting and Organelle Assembly, New York:Alan R. Liss Inc..

1987

Benson, S. A.; Hall, M. N.; Rasmussen, B. A. (1987). Signal sequence mutations that alter coupling of secretion and translation of an Escherichia coli outer membrane protein. Journal of Bacteriology, 169 (10), 4686-4691.

Hall, M. N.; Johnson, A. D. (1987). Homeo domain of the yeast repressor alpha 2 is a sequence-specific DNA-binding domain but is not sufficient for repression. Science, 237 (4818), 1007-12.

1986

Hall, M. N. (1986). Considerations on the mechanism of nuclear protein localization in yeast. , in: Hall, M. N.; , Nucleocytoplasmic Transport, Heidelberg:Springer Verlag, 247-252.

Hall, M. N. (1986). Nuclear protein localization signals in yeast. , in: Hall, M. N.; , Yeast cell biology, UCLA-Symposia on Molecular and Cellular Biology, New Series, New York:Alan R. Liss, Inc., 33.

1985

Silhavy, T. J.; Benson, S. A.; Hall, M. N. (1985). A mechanism to couple transport and export. , in: Silhavy, T. J.; Benson, S. A.; Hall, M. N.; , Microbiology - 1985, Washington:American Society for Microbiology.

Hall, M. N. (1985). Studies on the mechanism of nuclear protein localization in yeast. , in: Hall, M. N.; , Protein transport and secretion, New York:Cold Spring Harbor Laboratory Press, 196-200.

Benson, S. A.; Hall, M. N.; Silhavy, T. J. (1985). Genetic analysis of protein export in Escherichia coli K12. Annual Review of Biochemistry, 54, 101-134.

1984

Hall, M. N.; Hereford, L.; Herskowitz, I. (1984). Targeting of E. coli beta-galactosidase to the nucleus in yeast. Cell, 36 (4), 1057-1065.

Berman, M. L.; Jackson, D. E.; Fowler, A.; Zabin, I.; Christensen, L.; Fiil, N. P.; Hall, M. N. (1984). Gene fusion techniques: Cloning vectors for manipulating IacZ gene fusions. Gene Analysis Techniques, 1 (3), 43-51.

1983

Taylor, R. K.; Hall, M. N.; Silhavy, T. J. (1983). Isolation and characterization of mutations altering expression of the major outer membrane porin proteins using the local anaesthetic procaine. Journal of Molecular Biology, 166 (3), 273-282.

Hall, M. N.; Gabay, J.; Schwartz, M. (1983). Evidence for a coupling of synthesis and export of an outer membrane protein in Escherichia coli. Evidence for a coupling of synthesis and export of an outer membrane protein in Escherichia coli. The EMBO Journal, 2 (1), 15-19.

1982

Hall, M. N.; Schwartz, M. (1982). Reconsidering the early steps of protein secretion. Annales de Microbiologie, 133A (1), 123-127.

Benson, S.; Emr, S.; Hall, M. N.; Silhavy, T. J.; Sodergren, E. (1982). Genetic approaches to study export of lamB to the outer membrane. Annales de Microbiologie, 133A (1), 115-122.

Hall, M. N.; Schwartz, M.; Silhavy, T. J. (1982). Sequence information within the lamB genes in required for proper routing of the bacteriophage lambda receptor protein to the outer membrane of Escherichia coli K-12. Journal of Molecular Biology, 156 (1), 93-112.

Hall, M. N.; Gabay, J.; Debarbouille, M.; Schwartz, M. (1982). A role for mRNA secondary structure in the control of translation initiation. Nature, 295 (5850), 616-618.

1981

Taylor, R. K.; Hall, M. N.; Enquist, L.; Silhavy, T. J. (1981). Identification of OmpR: A positive regulatory protein controlling expression of the major outer membrane matrix porin proteins of Escherichia coli K-12. Journal of Bacteriology, 147 (1), 255-258.

Hall, M. N.; Silhavy, T. J. (1981). Genetic analysis of the ompB locus in Escherichia coli K-12. Journal of Molecular Biology, 151 (1), 1-15.

Hall, M. N.; Silhavy, T. J. (1981). The ompB locus and the regulation of the major outer membrane porin proteins of Escherichia coli K12. Journal of Molecular Biology, 146 (1), 23-43.

Hall, M. N.; Silhavy, T. J. (1981). Genetic analysis of the major outer membrane proteins of Escherichia coli. Annual Review of Genetics, 15, 91-142.

1980

Hall, M. N.; Emr, S. D.; Silhavy, T. J. (1980). Genetic studies on mechanisms of protein localization in Escherichia coli K-12. Journal of Supramolecular Structure, 13 (2), 147-163.

Moreno, F.; Fowler, A. V.; Hall, M. N.; Silhavy, T. J.; Zabin, I.; Schwartz, M. (1980). A signal sequence is not sufficient to lead beta-galactosidase out of the cytoplasm. Nature, 286 (5771), 356-359.

EMR, SD; HALL, MN; SILHAVY, TJ (1980). A mechanism of protein localization: the signal hypothesis and bacteria. The Journal of cell biology, 86 (3), 701-711.

1979

Hall, M. N.; Silhavy, T. J. (1979). Transcriptional regulation of Escherichia coli K-12 major outer membrane protein 1b. Journal of Bacteriology, 140 (2), 342-350.


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