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2020

Ma, Manxiu; Ramirez, Alexandro D.; Wang, Tong; Roberts, Rachel L.; Harmon, Katherine E.; Schoppik, David; Sharma, Avirale; Kuang, Christopher; Goei, Stephanie L.; Gagnon, James A.; Zimmerman, Steve; Tsai, Shengdar Q.; Reyon, Deepak; Joung, J. Keith; Aksay, Emre R. F.; Schier, Alexander F.; Pan, Y. Albert (2020). Zebrafish dscaml1 Deficiency Impairs Retinal Patterning and Oculomotor Function. Journal of Neuroscience, 40 (1), 143-158.

2019

Haesemeyer, Martin; Schier, Alexander F.; Engert, Florian (2019). Convergent Temperature Representations in Artificial and Biological Neural Networks. Neuron, 103 (6), 1123-1134.e6.

Wee, Caroline L.; Nikitchenko, Maxim; Wang, Wei-Chun; Luks-Morgan, Sasha J.; Song, Erin; Gagnon, James A.; Randlett, Owen; Bianco, Isaac H.; Lacoste, Alix M. B.; Glushenkova, Elena; Barrios, Joshua P.; Schier, Alexander F.; Kunes, Samuel; Engert, Florian; Douglass, Adam D. (2019). Zebrafish oxytocin neurons drive nocifensive behavior via brainstem premotor targets. Nature neuroscience, 22 (9), 1477-1492.

Randlett, Owen; Haesemeyer, Martin; Forkin, Greg; Shoenhard, Hannah; Schier, Alexander F.; Engert, Florian; Granato, Michael (2019). Distributed Plasticity Drives Visual Habituation Learning in Larval Zebrafish. Current biology : CB, 29 (8), 1337-1345.e4.

Thyme, Summer B.; Pieper, Lindsey M.; Li, Eric H.; Pandey, Shristi; Wang, Yiqun; Morris, Nathan S.; Sha, Carrie; Choi, Joo Won; Herrera, Kristian J.; Soucy, Edward R.; Zimmerman, Steve; Randlett, Owen; Greenwood, Joel; McCarroll, Steven A.; Schier, Alexander F. (2019). Phenotypic Landscape of Schizophrenia-Associated Genes Defines Candidates and Their Shared Functions. Cell, 177 (2), 478-491.e20.

Goudarzi, Mehdi; Berg, Kathryn; Pieper, Lindsey M.; Schier, Alexander F. (2019). Individual long non-coding RNAs have no overt functions in zebrafish embryogenesis, viability and fertility. eLife, 8, 8:e40815.

2018

Montague, Tessa G.; Gagnon, James A.; Schier, Alexander F. (2018). Conserved regulation of Nodal-mediated left-right patterning in zebrafish and mouse. Development (Cambridge, England), 145 (24), 9.

Raj, Bushra; Gagnon, James A.; Schier, Alexander F. (2018). Large-scale reconstruction of cell lineages using single-cell readout of transcriptomes and CRISPR-Cas9 barcodes by scGESTALT. Nature protocols, 13 (11), 2685-2713.

Almuedo-Castillo, María; Bläßle, Alexander; Mörsdorf, David; Marcon, Luciano; Soh, Gary H.; Rogers, Katherine W.; Schier, Alexander F.; Müller, Patrick (2018). Scale-invariant patterning by size-dependent inhibition of Nodal signalling. Nature cell biology, 20 (9), 1032-1042.

Haesemeyer, Martin; Robson, Drew N.; Li, Jennifer M.; Schier, Alexander F.; Engert, Florian (2018). A Brain-wide Circuit Model of Heat-Evoked Swimming Behavior in Larval Zebrafish. Neuron, 98 (4), 817-+.

Farrell, Jeffrey A.; Wang, Yiqun; Riesenfeld, Samantha J.; Shekhar, Karthik; Regev, Aviv; Schier, Alexander F. (2018). Single-cell reconstruction of developmental trajectories during zebrafish embryogenesis. Science (New York, N.Y.), 360 (6392), 979-+.

Raj, Bushra; Wagner, Daniel E.; McKenna, Aaron; Pandey, Shristi; Klein, Allon M.; Shendure, Jay; Gagnon, James A.; Schier, Alexander F. (2018). Simultaneous single-cell profiling of lineages and cell types in the vertebrate brain. Nature biotechnology, 36 (5), 442-450.

Pandey, Shristi; Shekhar, Karthik; Regev, Aviv; Schier, Alexander F. (2018). Comprehensive Identification and Spatial Mapping of Habenular Neuronal Types Using Single-Cell RNA-Seq. Current biology : CB, 28 (7), 1052-1065.e7.

Gagnon, James A.; Obbad, Kamal; Schier, Alexander F. (2018). The primary role of zebrafish nanog is in extra-embryonic tissue. Development (Cambridge, England), 145 (1), 9.

2017

Rabani, Michal; Pieper, Lindsey; Chew, Guo-Liang; Schier, Alexander F. (2017). A Massively Parallel Reporter Assay of 3' UTR Sequences Identifies In Vivo Rules for mRNA Degradation. Molecular Cell, 68 (6), 1083-+.

Rogers, Katherine W.; Lord, Nathan D.; Gagnon, James A.; Pauli, Andrea; Zimmerman, Steven; Aksel, Deniz C.; Reyon, Deepak; Tsai, Shengdar Q.; Joung, J. Keith; Schier, Alexander F. (2017). Nodal patterning without Lefty inhibitory feedback is functional but fragile. eLife, 6, 6:e28785.

Montague, Tessa G.; Schier, Alexander F. (2017). Vg1-Nodal heterodimers are the endogenous inducers of mesendoderm. eLife, 6, 6:e28183.

Norris, Megan L.; Pauli, Andrea; Gagnon, James A.; Lord, Nathan D.; Rogers, Katherine W.; Mosimann, Christian; Zon, Leonard I.; Schier, Alexander F. (2017). Toddler signaling regulates mesodermal cell migration downstream of Nodal signaling. eLife, 6, 6:e22626.

Escamilla, Christine Ochoa; Filonova, Irina; Walker, Angela K.; Xuan, Zhong X.; Holehonnur, Roopashri; Espinosa, Felipe; Liu, Shunan; Thyme, Summer B.; López-García, Isabel A.; Mendoza, Dorian B.; Usui, Noriyoshi; Ellegood, Jacob; Eisch, Amelia J.; Konopka, Genevieve; Lerch, Jason P.; Schier, Alexander F.; Speed, Haley E.; Powell, Craig M. (2017). Kctd13 deletion reduces synaptic transmission via increased RhoA. Nature, 551 (7679), 227-231.

Schoppik, David; Bianco, Isaac H.; Prober, David A.; Douglass, Adam D.; Robson, Drew N.; Li, Jennifer M. B.; Greenwood, Joel S. F.; Soucy, Edward; Engert, Florian; Schier, Alexander F. (2017). Gaze-Stabilizing Central Vestibular Neurons Project Asymmetrically to Extraocular Motoneuron Pools. The Journal of Neuroscience, 37 (47), 11353-11365.

Freyer, Laina; Hsu, Chih-Wei; Nowotschin, Sonja; Pauli, Andrea; Ishida, Junji; Kuba, Keiji; Fukamizu, Akiyoshi; Schier, Alexander F.; Hoodless, Pamela A.; Dickinson, Mary E.; Hadjantonakis, Anna-Katerina (2017). Loss of Apela Peptide in Mice Causes Low Penetrance Embryonic Lethality and Defects in Early Mesodermal Derivatives. Cell reports, 20 (9), 2116-2130.

Hildebrand, David Grant Colburn; Cicconet, Marcelo; Torres, Russel Miguel; Choi, Woohyuk; Quan, Tran Minh; Moon, Jungmin; Wetzel, Arthur Willis; Scott Champion, Andrew; Graham, Brett Jesse; Randlett, Owen; Plummer, George Scott; Portugues, Ruben; Bianco, Isaac Henry; Saalfeld, Stephan; Baden, Alexander David; Lillaney, Kunal; Burns, Randal; Vogelstein, Joshua Tzvi; Schier, Alexander Franz; Lee, Wei-Chung Allen; Jeong, Won-Ki; Lichtman, Jeff William; Engert, Florian (2017). Whole-brain serial-section electron microscopy in larval zebrafish. Nature, 545 (7654), 345-349.

2016

Thyme, Summer B.; Akhmetova, Laila; Montague, Tessa G.; Valen, Eivind; Schier, Alexander F. (2016). Internal guide RNA interactions interfere with Cas9-mediated cleavage. Nature communications, 7, 11750.

McKenna, Aaron; Findlay, Gregory M.; Gagnon, James A.; Horwitz, Marshall S.; Schier, Alexander F.; Shendure, Jay (2016). Whole-organism lineage tracing by combinatorial and cumulative genome editing. Science (New York, N.Y.), 353 (6298), aaf7907.

Chew, Guo-Liang; Pauli, Andrea; Schier, Alexander F. (2016). Conservation of uORF repressiveness and sequence features in mouse, human and zebrafish. Nature communications, 7, 11663.

Thyme, Summer B.; Schier, Alexander F. (2016). Polq-Mediated End Joining Is Essential for Surviving DNA Double-Strand Breaks during Early Zebrafish Development. Cell reports, 15 (4), 707-714.

Li-Villarreal, Nanbing; Forbes, Meredyth M.; Loza, Andrew J.; Chen, Jiakun; Ma, Taylur; Helde, Kathryn; Moens, Cecilia B.; Shin, Jimann; Sawada, Atsushi; Hindes, Anna E.; Dubrulle, Julien; Schier, Alexander F.; Longmore, Gregory D.; Marlow, Florence L.; Solnica-Krezel, Lilianna (2016). Dachsous1b cadherin regulates actin and microtubule cytoskeleton during early zebrafish embryogenesis. Development, 143 (10), 1832.

Dunn, Timothy W.; Mu, Yu; Narayan, Sujatha; Randlett, Owen; Naumann, Eva A.; Yang, Chao-Tsung; Schier, Alexander F.; Freeman, Jeremy; Engert, Florian; Ahrens, Misha B. (2016). Brain-wide mapping of neural activity controlling zebrafish exploratory locomotion. eLife, 5, e12741.

Chiu, Cindy N.; Rihel, Jason; Lee, Daniel A.; Singh, Chanpreet; Mosser, Eric A.; Chen, Shijia; Sapin, Viveca; Pham, Uyen; Engle, Jae; Niles, Brett J.; Montz, Christin J.; Chakravarthy, Sridhara; Zimmerman, Steven; Salehi-Ashtiani, Kourosh; Vidal, Marc; Schier, Alexander F.; Prober, David A. (2016). A Zebrafish Genetic Screen Identifies Neuromedin U as a Regulator of Sleep/Wake States. Neuron, 89 (4), 842-856.

2015

Randlett, Owen; Wee, Caroline L.; Naumann, Eva A.; Nnaemeka, Onyeka; Schoppik, David; Fitzgerald, James E.; Portugues, Ruben; Lacoste, Alix M. B.; Riegler, Clemens; Engert, Florian; Schier, Alexander F. (2015). Whole-brain activity mapping onto a zebrafish brain atlas. Nature Methods, 12 (11), 1039-46.

Haesemeyer, Martin; Robson, Drew N.; Li, Jennifer M.; Schier, Alexander F.; Engert, Florian (2015). The structure and timescales of heat perception in larval zebrafish. Cell Systems, 1 (5), 338-348.

Pauli, Andrea; Montague, Tessa G.; Lennox, Kim A.; Behlke, Mark A.; Schier, Alexander F. (2015). Antisense Oligonucleotide-Mediated Transcript Knockdown in Zebrafish. PloS one, 10 (10), e0139504.

Li-Villarreal, Nanbing; Forbes, Meredyth M.; Loza, Andrew J.; Chen, Jiakun; Ma, Taylur; Helde, Kathryn; Moens, Cecilia B.; Shin, Jimann; Sawada, Atsushi; Hindes, Anna E.; Dubrulle, Julien; Schier, Alexander F.; Longmore, Gregory D.; Marlow, Florence L.; Solnica-Krezel, Lilianna (2015). Dachsous1b cadherin regulates actin and microtubule cytoskeleton during early zebrafish embryogenesis. Development, 142 (15), 2704-18.

Lacoste, Alix M. B.; Schoppik, David; Robson, Drew N.; Haesemeyer, Martin; Portugues, Ruben; Li, Jennifer M.; Randlett, Owen; Wee, Caroline L.; Engert, Florian; Schier, Alexander F. (2015). A convergent and essential interneuron pathway for Mauthner-cell-mediated escapes. Current biology : CB, 25 (11), 1526-1534.

Merkle, Florian T.; Neuhausser, Werner M.; Santos, David; Valen, Eivind; Gagnon, James A.; Maas, Kristi; Sandoe, Jackson; Schier, Alexander F.; Eggan, Kevin (2015). Efficient CRISPR-Cas9-mediated generation of knockin human pluripotent stem cells lacking undesired mutations at the targeted locus. Cell Reports, 11 (6), 875-883.

Dubrulle, Julien; Jordan, Benjamin M.; Akhmetova, Laila; Farrell, Jeffrey A.; Kim, Seok-Hyung; Solnica-Krezel, Lilianna; Schier, Alexander F. (2015). Response to Nodal morphogen gradient is determined by the kinetics of target gene induction. eLife, 4, e05042.

Satija, Rahul; Farrell, Jeffrey A.; Gennert, David; Schier, Alexander F.; Regev, Aviv (2015). Spatial reconstruction of single-cell gene expression data. Nature biotechnology, 33 (5), 495-502.

Liu, Justin; Merkle, Florian T.; Gandhi, Avni V.; Gagnon, James A.; Woods, Ian G.; Chiu, Cindy N.; Shimogori, Tomomi; Schier, Alexander F.; Prober, David A. (2015). Evolutionarily conserved regulation of hypocretin neuron specification by Lhx9. Development, 142 (6), 1113-24.

Mundell, Nathan A.; Beier, Kevin T.; Pan, Y. Albert; Lapan, Sylvain W.; Göz Aytürk, Didem; Berezovskii, Vladimir K.; Wark, Abigail R.; Drokhlyansky, Eugene; Bielecki, Jan; Born, Richard T.; Schier, Alexander F.; Cepko, Constance L. (2015). Vesicular stomatitis virus enables gene transfer and transsynaptic tracing in a wide range of organisms. Journal of Comparative Neurology, 523 (11), 1639-63.

Merkle, Florian T.; Maroof, Asif; Wataya, Takafumi; Sasai, Yoshiki; Studer, Lorenz; Eggan, Kevin; Schier, Alexander F. (2015). Generation of neuropeptidergic hypothalamic neurons from human pluripotent stem cells. Development (Cambridge, England), 142 (4), 633-43.

Rogers, Katherine W.; Blässle, Alexander; Schier, Alexander F.; Müller, Patrick (2015). Measuring protein stability in living zebrafish embryos using fluorescence decay after photoconversion (FDAP). Journal of visualized experiments, (95), 52266.

Haesemeyer, Martin; Schier, Alexander F. (2015). The study of psychiatric disease genes and drugs in zebrafish. Current Opinion in Neurobiology, 30, 122-130.

Pauli, Andrea; Valen, Eivind; Schier, Alexander F. (2015). Identifying (non-)coding RNAs and small peptides: challenges and opportunities. BioEssays : news and reviews in molecular, cellular and developmental biology, 37 (1), 103-12.

2014

Rabani, Michal; Raychowdhury, Raktima; Jovanovic, Marko; Rooney, Michael; Stumpo, Deborah J; Pauli, Andrea; Hacohen, Nir; Schier, Alexander F; Blackshear, Perry J; Friedman, Nir; Amit, Ido; Regev, Aviv (2014). High-resolution sequencing and modeling identifies distinct dynamic RNA regulatory strategies. Cell, 159 (7), 1698-710.

Schier, Alexander F (2014). Obituary: Walter J. Gehring (1939-2014). Development (Cambridge, England), 141 (17), 3289-91.

Richter, Constance; Woods, Ian G; Schier, Alexander F (2014). Neuropeptidergic control of sleep and wakefulness. Annual review of neuroscience, 37, 503-31.

Gagnon, James A; Valen, Eivind; Thyme, Summer B; Huang, Peng; Akhmetova, Laila; Ahkmetova, Laila; Pauli, Andrea; Montague, Tessa G; Zimmerman, Steven; Richter, Constance; Schier, Alexander F (2014). Efficient mutagenesis by Cas9 protein-mediated oligonucleotide insertion and large-scale assessment of single-guide RNAs. PloS one, 9 (5), e98186.

Woods, Ian G; Schoppik, David; Shi, Veronica J; Zimmerman, Steven; Coleman, Haley A; Greenwood, Joel; Soucy, Edward R; Schier, Alexander F (2014). Neuropeptidergic signaling partitions arousal behaviors in zebrafish. The Journal of neuroscience : the official journal of the Society for Neuroscience, 34 (9), 3142-60.

Pauli, Andrea; Norris, Megan L; Valen, Eivind; Chew, Guo-Liang; Gagnon, James A; Zimmerman, Steven; Mitchell, Andrew; Ma, Jiao; Dubrulle, Julien; Reyon, Deepak; Tsai, Shengdar Q; Joung, J Keith; Saghatelian, Alan; Schier, Alexander F (2014). Toddler: an embryonic signal that promotes cell movement via Apelin receptors. Science (New York, N.Y.), 343 (6172), 1248636.

Zhang, Yong; Vastenhouw, Nadine L; Feng, Jianxing; Fu, Kai; Wang, Chenfei; Ge, Ying; Pauli, Andrea; van Hummelen, Paul; Schier, Alexander F; Liu, X Shirley (2014). Canonical nucleosome organization at promoters forms during genome activation. Genome research, 24 (2), 260-6.

2013

Schier, Alexander F (2013). Should I stay or should I go: neuromodulators of behavioral states. Cell, 154 (5), 955-956.

Pan, Y Albert; Freundlich, Tom; Weissman, Tamily A; Schoppik, David; Wang, X Cindy; Zimmerman, Steve; Ciruna, Brian; Sanes, Joshua R; Lichtman, Jeff W; Schier, Alexander F (2013). Zebrabow: multispectral cell labeling for cell tracing and lineage analysis in zebrafish. Development (Cambridge, England), 140 (13), 2835-46.

Rihel, Jason; Schier, Alexander F (2013). Sites of action of sleep and wake drugs: insights from model organisms. Current opinion in neurobiology, 23 (5), 831-40.

Chew, Guo-Liang; Pauli, Andrea; Rinn, John L; Regev, Aviv; Schier, Alexander F; Valen, Eivind (2013). Ribosome profiling reveals resemblance between long non-coding RNAs and 5' leaders of coding RNAs. Development (Cambridge, England), 140 (13), 2828-34.

Xiong, Fengzhu; Tentner, Andrea R; Huang, Peng; Gelas, Arnaud; Mosaliganti, Kishore R; Souhait, Lydie; Rannou, Nicolas; Swinburne, Ian A; Obholzer, Nikolaus D; Cowgill, Paul D; Schier, Alexander F; Megason, Sean G (2013). Specified neural progenitors sort to form sharp domains after noisy Shh signaling. Cell, 153 (3), 550-61.

Schier, Alexander F (2013). Genomics: Zebrafish earns its stripes. Nature, 496 (7446), 443-4.

Müller, Patrick; Rogers, Katherine W; Yu, Shuizi R; Brand, Michael; Schier, Alexander F (2013). Morphogen transport. Development (Cambridge, England), 140 (8), 1621-38.

Levitz, Joshua; Pantoja, Carlos; Gaub, Benjamin; Janovjak, Harald; Reiner, Andreas; Hoagland, Adam; Schoppik, David; Kane, Brian; Stawski, Philipp; Schier, Alexander F; Trauner, Dirk; Isacoff, Ehud Y (2013). Optical control of metabotropic glutamate receptors. Nature neuroscience, 16 (4), 507-16.

Varshney, Gaurav K; Lu, Jing; Gildea, Derek E; Huang, Haigen; Pei, Wuhong; Yang, Zhongan; Huang, Sunny C; Schoenfeld, David; Pho, Nam H; Casero, David; Hirase, Takashi; Mosbrook-Davis, Deborah; Zhang, Suiyuan; Jao, Li-En; Zhang, Bo; Woods, Ian G; Zimmerman, Steven; Schier, Alexander F; Wolfsberg, Tyra G; Pellegrini, Matteo; Burgess, Shawn M; Lin, Shuo (2013). A large-scale zebrafish gene knockout resource for the genome-wide study of gene function. Genome research, 23 (4), 727-35.

2012

Bianco, Isaac H; Ma, Leung-Hang; Schoppik, David; Robson, Drew N; Orger, Michael B; Beck, James C; Li, Jennifer M; Schier, Alexander F; Engert, Florian; Baker, Robert (2012). The tangential nucleus controls a gravito-inertial vestibulo-ocular reflex. Current biology : CB, 22 (14), 1285-95.

Huang, Peng; Xiong, Fengzhu; Megason, Sean G; Schier, Alexander F (2012). Attenuation of Notch and Hedgehog signaling is required for fate specification in the spinal cord. PLoS genetics, 8 (6), e1002762.

Ahrens, Misha B; Li, Jennifer M; Orger, Michael B; Robson, Drew N; Schier, Alexander F; Engert, Florian; Portugues, Ruben (2012). Brain-wide neuronal dynamics during motor adaptation in zebrafish. Nature, 485 (7399), 471-7.

Panizzi, Jennifer R; Becker-Heck, Anita; Castleman, Victoria H; Al-Mutairi, Dalal A; Liu, Yan; Loges, Niki T; Pathak, Narendra; Austin-Tse, Christina; Sheridan, Eamonn; Schmidts, Miriam; Olbrich, Heike; Werner, Claudius; Häffner, Karsten; Hellman, Nathan; Chodhari, Rahul; Gupta, Amar; Kramer-Zucker, Albrecht; Olale, Felix; Burdine, Rebecca D; Schier, Alexander F; O'Callaghan, Christopher; Chung, Eddie M K; Reinhardt, Richard; Mitchison, Hannah M; King, Stephen M; Omran, Heymut; Drummond, Iain A (2012). CCDC103 mutations cause primary ciliary dyskinesia by disrupting assembly of ciliary dynein arms. Nature genetics, 44 (6), 714-9.

Vastenhouw, Nadine L; Schier, Alexander F (2012). Bivalent histone modifications in early embryogenesis. Current opinion in cell biology, 24 (3), 374-86.

Müller, Patrick; Rogers, Katherine W; Jordan, Ben M; Lee, Joon S; Robson, Drew; Ramanathan, Sharad; Schier, Alexander F (2012). Differential diffusivity of Nodal and Lefty underlies a reaction-diffusion patterning system. Science (New York, N.Y.), 336 (6082), 721-4.

Low, Sean E; Woods, Ian G; Lachance, Mathieu; Ryan, Joel; Schier, Alexander F; Saint-Amant, Louis (2012). Touch responsiveness in zebrafish requires voltage-gated calcium channel 2.1b. Journal of neurophysiology, 108 (1), 148-59.

Stooke-Vaughan, Georgina A; Huang, Peng; Hammond, Katherine L; Schier, Alexander F; Whitfield, Tanya T (2012). The role of hair cells, cilia and ciliary motility in otolith formation in the zebrafish otic vesicle. Development (Cambridge, England), 139 (10), 1777-87.

Xu, Cong; Fan, Zi Peng; Müller, Patrick; Fogley, Rachel; DiBiase, Anthony; Trompouki, Eirini; Unternaehrer, Juli; Xiong, Fengzhu; Torregroza, Ingrid; Evans, Todd; Megason, Sean G; Daley, George Q; Schier, Alexander F; Young, Richard A; Zon, Leonard I (2012). Nanog-like regulates endoderm formation through the Mxtx2-Nodal pathway. Developmental cell, 22 (3), 625-38.

Pan, Y Albert; Caron, Sophie J C; Schier, Alexander F (2012). BAPTI and BAPTISM birthdating of neurons in zebrafish. Cold Spring Harbor protocols, 2012 (1), 87-92.

Pan, Y Albert; Choy, Margaret; Prober, David A; Schier, Alexander F (2012). Robo2 determines subtype-specific axonal projections of trigeminal sensory neurons. Development (Cambridge, England), 139 (3), 591-600.

Pauli, Andrea; Valen, Eivind; Lin, Michael F; Garber, Manuel; Vastenhouw, Nadine L; Levin, Joshua Z; Fan, Lin; Sandelin, Albin; Rinn, John L; Regev, Aviv; Schier, Alexander F (2012). Systematic identification of long noncoding RNAs expressed during zebrafish embryogenesis. Genome research, 22 (3), 577-91.

Rihel, Jason; Schier, Alexander F (2012). Behavioral screening for neuroactive drugs in zebrafish. Developmental neurobiology, 72 (3), 373-85.

2011

Laukens, Bram; Jennewein, Claudia; Schenk, Barbara; Vanlangenakker, Nele; Schier, Alexander; Cristofanon, Silvia; Zobel, Kerry; Deshayes, Kurt; Vucic, Domagoj; Jeremias, Irmela; Bertrand, Mathieu J M; Vandenabeele, Peter; Fulda, Simone (2011). Smac mimetic bypasses apoptosis resistance in FADD- or caspase-8-deficient cells by priming for tumor necrosis factor α-induced necroptosis. Neoplasia (New York, N.Y.), 13 (10), 971-9.

Rogers, Katherine W; Schier, Alexander F (2011). Morphogen gradients: from generation to interpretation. Annual review of cell and developmental biology, 27, 377-407.

Müller, Patrick; Schier, Alexander F (2011). Extracellular movement of signaling molecules. Developmental cell, 21 (1), 145-58.

Pauli, Andrea; Rinn, John L; Schier, Alexander F (2011). Non-coding RNAs as regulators of embryogenesis. Nature reviews. Genetics, 12 (2), 136-49.

Pan, Y Albert; Livet, Jean; Sanes, Joshua R; Lichtman, Jeff W; Schier, Alexander F (2011). Multicolor Brainbow imaging in zebrafish. Cold Spring Harbor protocols, 2011 (1), pdb.prot5546.

2010

Rihel, Jason; Prober, David A; Schier, Alexander F (2010). Monitoring sleep and arousal in zebrafish. Methods in cell biology, 100, 281-94.

Vastenhouw, Nadine L; Zhang, Yong; Woods, Ian G; Imam, Farhad; Regev, Aviv; Liu, X Shirley; Rinn, John; Schier, Alexander F (2010). Chromatin signature of embryonic pluripotency is established during genome activation. Nature, 464 (7290), 922-6.

Naumann, Eva A; Kampff, Adam R; Prober, David A; Schier, Alexander F; Engert, Florian (2010). Monitoring neural activity with bioluminescence during natural behavior. Nature neuroscience, 13 (4), 513-20.

Harvey, Steven A; Tümpel, Stefan; Dubrulle, Julien; Schier, Alexander F; Smith, James C (2010). no tail integrates two modes of mesoderm induction. Development (Cambridge, England), 137 (7), 1127-35.

Rihel, Jason; Prober, David A; Arvanites, Anthony; Lam, Kelvin; Zimmerman, Steven; Jang, Sumin; Haggarty, Stephen J; Kokel, David; Rubin, Lee L; Peterson, Randall T; Schier, Alexander F (2010). Zebrafish behavioral profiling links drugs to biological targets and rest/wake regulation. Science (New York, N.Y.), 327 (5963), 348-51.

2009

Schier, Alexander F (2009). Nodal morphogens. Cold Spring Harbor perspectives in biology, 1 (5), a003459.

Schier, Alexander F; Needleman, Daniel (2009). Developmental biology: Rise of the source-sink model. Nature, 461 (7263), 480-1.

Huang, Peng; Schier, Alexander F (2009). Dampened Hedgehog signaling but normal Wnt signaling in zebrafish without cilia. Development (Cambridge, England), 136 (18), 3089-98.

2008

de Campos-Baptista, Maria Ines Medeiros; Holtzman, Nathalia Glickman; Yelon, Deborah; Schier, Alexander F (2008). Nodal signaling promotes the speed and directional movement of cardiomyocytes in zebrafish. Developmental dynamics : an official publication of the American Association of Anatomists, 237 (12), 3624-33.

Prober, David A; Zimmerman, Steven; Myers, Benjamin R; McDermott, Brian M; Kim, Seok-Hyung; Caron, Sophie; Rihel, Jason; Solnica-Krezel, Lilianna; Julius, David; Hudspeth, A J; Schier, Alexander F (2008). Zebrafish TRPA1 channels are required for chemosensation but not for thermosensation or mechanosensory hair cell function. The Journal of neuroscience : the official journal of the Society for Neuroscience, 28 (40), 10102-10.

Caron, Sophie J C; Prober, David; Choy, Margaret; Schier, Alexander F (2008). In vivo birthdating by BAPTISM reveals that trigeminal sensory neuron diversity depends on early neurogenesis. Development (Cambridge, England), 135 (19), 3259-69.

Douglass, Adam D; Kraves, Sebastian; Deisseroth, Karl; Schier, Alexander F; Engert, Florian (2008). Escape behavior elicited by single, channelrhodopsin-2-evoked spikes in zebrafish somatosensory neurons. Current biology : CB, 18 (15), 1133-7.

Woods, Ian G; Schier, Alexander F (2008). Targeted mutagenesis in zebrafish. Nature biotechnology, 26 (6), 650-1.

Knaut, Holger; Schier, Alexander F (2008). Clearing the path for germ cells. Cell, 132 (3), 337-9.

Choi, Philip S; Zakhary, Lisa; Choi, Wen-Yee; Caron, Sophie; Alvarez-Saavedra, Ezequiel; Miska, Eric A; McManus, Mike; Harfe, Brian; Giraldez, Antonio J; Horvitz, H Robert; Schier, Alexander F; Dulac, Catherine (2008). Members of the miRNA-200 family regulate olfactory neurogenesis. Neuron, 57 (1), 41-55.

2007

Bennett, James T; Stickney, Heather L; Choi, Wen-Yee; Ciruna, Brian; Talbot, William S; Schier, Alexander F (2007). Maternal nodal and zebrafish embryogenesis. Nature, 450 (7167), E1-2;discussionE2-4.

Karkera, J D; Lee, J S; Roessler, E; Banerjee-Basu, S; Ouspenskaia, M V; Mez, J; Goldmuntz, E; Bowers, P; Towbin, J; Belmont, J W; Baxevanis, A D; Schier, A F; Muenke, M (2007). Loss-of-function mutations in growth differentiation factor-1 (GDF1) are associated with congenital heart defects in humans. American journal of human genetics, 81 (5), 987-94.

Choi, Wen-Yee; Giraldez, Antonio J; Schier, Alexander F (2007). Target protectors reveal dampening and balancing of Nodal agonist and antagonist by miR-430. Science (New York, N.Y.), 318 (5848), 271-4.

Schier, Alexander F (2007). The maternal-zygotic transition: death and birth of RNAs. Science (New York, N.Y.), 316 (5823), 406-7.

Bennett, James T; Joubin, Katherine; Cheng, Simon; Aanstad, Pia; Herwig, Ralf; Clark, Matthew; Lehrach, Hans; Schier, Alexander F (2007). Nodal signaling activates differentiation genes during zebrafish gastrulation. Developmental biology, 304 (2), 525-40.

2006

Schier, A F; Giraldez, A J (2006). MicroRNA function and mechanism: insights from zebra fish. Cold Spring Harbor symposia on quantitative biology, 71, 195-203.

Prober, David A; Rihel, Jason; Onah, Anthony A; Sung, Rou-Jia; Schier, Alexander F (2006). Hypocretin/orexin overexpression induces an insomnia-like phenotype in zebrafish. The Journal of neuroscience : the official journal of the Society for Neuroscience, 26 (51), 13400-10.

Mishima, Yuichiro; Giraldez, Antonio J; Takeda, Yasuaki; Fujiwara, Toshinobu; Sakamoto, Hiroshi; Schier, Alexander F; Inoue, Kunio (2006). Differential regulation of germline mRNAs in soma and germ cells by zebrafish miR-430. Current biology : CB, 16 (21), 2135-42.

Obara, Tomoko; Mangos, Steven; Liu, Yan; Zhao, Jinhua; Wiessner, Stephanie; Kramer-Zucker, Albrecht G; Olale, Felix; Schier, Alexander F; Drummond, Iain A (2006). Polycystin-2 immunolocalization and function in zebrafish. Journal of the American Society of Nephrology : JASN, 17 (10), 2706-18.

Giraldez, Antonio J; Mishima, Yuichiro; Rihel, Jason; Grocock, Russell J; Van Dongen, Stijn; Inoue, Kunio; Enright, Anton J; Schier, Alexander F (2006). Zebrafish MiR-430 promotes deadenylation and clearance of maternal mRNAs. Science (New York, N.Y.), 312 (5770), 75-9.

Ciruna, Brian; Jenny, Andreas; Lee, Diana; Mlodzik, Marek; Schier, Alexander F (2006). Planar cell polarity signalling couples cell division and morphogenesis during neurulation. Nature, 439 (7073), 220-4.

2005

Schier, Alexander F (2005). Axis formation: squint comes into focus. Current biology : CB, 15 (24), R1002-5.

Schier, Alexander F; Talbot, William S (2005). Molecular genetics of axis formation in zebrafish. Annual review of genetics, 39, 561-613.

Knaut, Holger; Blader, Patrick; Strähle, Uwe; Schier, Alexander F; 4 (2005). Assembly of trigeminal sensory ganglia by chemokine signaling. Neuron, 47 (5), 653-66.

Sagasti, Alvaro; Guido, Matthew R; Raible, David W; Schier, Alexander F (2005). Repulsive interactions shape the morphologies and functional arrangement of zebrafish peripheral sensory arbors. Current biology : CB, 15 (9), 804-14.

Kramer-Zucker, Albrecht G; Olale, Felix; Haycraft, Courtney J; Yoder, Bradley K; Schier, Alexander F; Drummond, Iain A (2005). Cilia-driven fluid flow in the zebrafish pronephros, brain and Kupffer's vesicle is required for normal organogenesis. Development (Cambridge, England), 132 (8), 1907-21.

Giraldez, Antonio J; Cinalli, Ryan M; Glasner, Margaret E; Enright, Anton J; Thomson, J Michael; Baskerville, Scott; Hammond, Scott M; Bartel, David P; Schier, Alexander F (2005). MicroRNAs regulate brain morphogenesis in zebrafish. Science (New York, N.Y.), 308 (5723), 833-8.

Dutta, Sunit; Dietrich, Jens-Erik; Aspöck, Gudrun; Burdine, Rebecca D; Schier, Alexander; Westerfield, Monte; Varga, Zoltán M (2005). pitx3 defines an equivalence domain for lens and anterior pituitary placode. Development (Cambridge, England), 132 (7), 1579-90.

Le Good, J Ann; Joubin, Katherine; Giraldez, Antonio J; Ben-Haim, Nadav; Beck, Séverine; Chen, Yu; Schier, Alexander F; Constam, Daniel B (2005). Nodal stability determines signaling range. Current biology : CB, 15 (1), 31-6.

Tyurina, Oksana V; Guner, Burcu; Popova, Evgenya; Feng, Jianchi; Schier, Alexander F; Kohtz, Jhumku D; Karlstrom, Rolf O (2005). Zebrafish Gli3 functions as both an activator and a repressor in Hedgehog signaling. Developmental biology, 277 (2), 537-56.

2004

Schier, Alexander (2004). Alexander Schier. Current biology : CB, 14 (13), R494.

Cheng, Simon K; Olale, Felix; Brivanlou, Ali H; Schier, Alexander F (2004). Lefty blocks a subset of TGFbeta signals by antagonizing EGF-CFC coreceptors. PLoS biology, 2 (2), E30.

Schier, Alexander F (2004). Developmental biology: tail of decay. Nature, 427 (6973), 403-4.

2003

Schier, Alexander F (2003). Nodal signaling in vertebrate development. Annual review of cell and developmental biology, 19, 589-621.

Kunwar, Prabhat S; Zimmerman, Steven; Bennett, James T; Chen, Yu; Whitman, Malcolm; Schier, Alexander F (2003). Mixer/Bon and FoxH1/Sur have overlapping and divergent roles in Nodal signaling and mesendoderm induction. Development (Cambridge, England), 130 (23), 5589-99.

Dougan, Scott T; Warga, Rachel M; Kane, Donald A; Schier, Alexander F; Talbot, William S (2003). The role of the zebrafish nodal-related genes squint and cyclops in patterning of mesendoderm. Development (Cambridge, England), 130 (9), 1837-51.

Schier, Alexander F (2003). Chemokine signaling: rules of attraction. Current biology : CB, 13 (5), R192-4.

Karlstrom, Rolf O; Tyurina, Oksana V; Kawakami, Atsushi; Nishioka, Noriyuki; Talbot, William S; Sasaki, Hiroshi; Schier, Alexander F (2003). Genetic analysis of zebrafish gli1 and gli2 reveals divergent requirements for gli genes in vertebrate development. Development (Cambridge, England), 130 (8), 1549-64.

Cheng, Simon K; Olale, Felix; Bennett, James T; Brivanlou, Ali H; Schier, Alexander F (2003). EGF-CFC proteins are essential coreceptors for the TGF-beta signals Vg1 and GDF1. Genes & development, 17 (1), 31-6.

2002

Chen, Yu; Schier, Alexander F (2002). Lefty proteins are long-range inhibitors of squint-mediated nodal signaling. Current biology : CB, 12 (24), 2124-8.

Ciruna, Brian; Weidinger, Gilbert; Knaut, Holger; Thisse, Bernard; Thisse, Christine; Raz, Erez; Schier, Alexander F (2002). Production of maternal-zygotic mutant zebrafish by germ-line replacement. Proceedings of the National Academy of Sciences of the United States of America, 99 (23), 14919-24.

Moon, Ho-Sang; Jacobson, Eric M; Khersonsky, Sonya M; Luzung, Michael R; Walsh, Daniel P; Xiong, Wennan; Lee, Jae Wook; Parikh, Puja B; Lam, Jennifer C; Kang, Tae-Wook; Rosania, Gustavo R; Schier, Alexander F; Chang, Young-Tae (2002). A novel microtubule destabilizing entity from orthogonal synthesis of triazine library and zebrafish embryo screening. Journal of the American Chemical Society, 124 (39), 11608-9.

de la Cruz, June M; Bamford, Richard N; Burdine, Rebecca D; Roessler, Erich; Barkovich, A James; Donnai, Dian; Schier, Alexander F; Muenke, Maximilian (2002). A loss-of-function mutation in the CFC domain of TDGF1 is associated with human forebrain defects. Human genetics, 110 (5), 422-8.

Yamashita, Susumu; Miyagi, Chiemi; Carmany-Rampey, Amanda; Shimizu, Takashi; Fujii, Ritsuko; Schier, Alexander F; Hirano, Toshio (2002). Stat3 Controls Cell Movements during Zebrafish Gastrulation. Developmental cell, 2 (3), 363-75.

Kimelman David,; Schier Alexander F,: Mesoderm Induction and Patterning, in: Solnica-Krezel Lilianna,(Ed.). (2002). Pattern Formation in Zebrafish, Berlin, Heidelberg: Springer, Berlin, Heidelberg, 40, 15-27.

1994

GEHRING, WJ; QIAN, YQ; BILLETER, M; FURUKUBOTOKUNAGA, K; SCHIER, AF; RESENDEZPEREZ, D; AFFOLTER, M; OTTING, G; WUTHRICH, K (1994). Homeodomain-DNA recognition. Cell, 78 (2), 211-223.

1993

Schier, A F; Gehring, W J (1993). Functional specificity of the homeodomain protein fushi tarazu : the role of DNA-binding specificity in vivo. Proceedings of the National Academy of Sciences of the United States of America, 90 (4), 1450-4.

Schier, A F; Gehring, W J (1993). Analysis of a fushi tarazu autoregulatory element : multiple sequence elements contribute to enhancer activity. The EMBO journal, 12 (3), 1111-9.

Affolter, M; Walldorf, U; Kloter, U; Schier, A F; Gehring, W J (1993). Regional repression of a Drosophila POU box gene in the endoderm involves inductive interactions between germ layers. Development, 117 (4), 1199-210.

1992

Schier, A F; Gehring, W J (1992). Direct homeodomain-DNA interaction in the autoregulation of the fushi tarazu gene. Nature, 356 (6372), 804-7.

1990

Affolter, M; Schier, A; Gehring, W J (1990). Homeodomain proteins and the regulation of gene expression. Current opinion in cell biology, 2 (3), 485-95.

Gibson, G; Schier, A; LeMotte, P; Gehring, W J (1990). The specificities of Sex combs reduced and Antennapedia are defined by a distinct portion of each protein that includes the homeodomain. Cell, 62 (6), 1087-103.

Pick, L; Schier, A; Affolter, M; Schmidt-Glenewinkel, T; Gehring, W J (1990). Analysis of the ftz upstream element : germ layer-specific enhancers are independently autoregulated. Genes & development, 4 (7), 1224-39.


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