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Summer Vacation in the Lab

25 students from Basel-Stadt and Basel-Land secured one of the few places at the Basel Summer Science Academy 2024 at the Biozentrum. The program was established in 2019 to give high school students insight into the research…


How bacteria reinforce their protective shield against stress

When infecting a host, pathogens not only need to evade the immune defense but also to survive diverse living conditions, such as the acidic conditions in the stomach or the salty intestinal environment. Gram negative…


Molecular bodyguards against Parkinson's disease

Parkinson's disease is one of the most common neurodegenerative disorders. In Switzerland, about 15,000 people are affected. Because of the worldwide rise in life expectancy, a rapid increase in Parkinson's cases is expected…


Like a zipper – How cells form new blood vessels

The blood vessels form a widely ramified supply system that passes through our body from head to toe. They serve as pathways for blood cells and transport oxygen as well as nutrients into each individual organ. In the…


Acrobatic duo in the cells

Misfolded proteins are non-functional and cause cell damage. In order to prevent this, there is a whole arsenal of proteins – called chaperones – that assist with folding and carry out quality control. In the bacterium…


Engineered enzymes: String pullers in cell communication

Cells are the building blocks of all living creatures. In order to form a complex organism and stay healthy, cells need to communicate with each other and integrate the response within themselves. A group of enzymes,…


Two new SNSF Ambizione Fellows at the Biozentrum

The Ambizione fellow Dr. Janani Durairaj , project leader in the research group of Prof. Torsten Schwede, will study the protein universe of viruses in more detail. Viruses have evolved diverse pathogenic mechanisms and…


Blood vessel formation: how the vascular cells respond to blood pressure

Throughout our body there is a dense, widely ramified network of blood vessels. It is estimated to be about 150,000 kilometers in length. The vessels supply all cells, even those in most far away regions of the body with…


The mystery of sleep: How does the brain know when it’s time to sleep?

Sleep is universal and essential: not only humans, but even flies and jellyfish sleep for a significant portion of the day. Like eating or mating, sleep is also controlled by motivational drives. Our drive to sleep increases…


New way to improve the efficacy of innovative RNA therapies

In modern medicine, personalized therapies are becoming increasingly important – particularly in the treatment of genetic diseases. One such promising approach is the use of so-called antisense oligonucleotides (ASOs). These…