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How pathogens switch on their virulence

Since the late 20th century, diseases that are transmitted from animals to humans, so-called zoonoses, have been on the rise. One of these is leptospirosis, an infectious disease that is becoming more common due to climate…


Novel strategies for treating bacterial infections without antibiotics

Novel strategies for treating bacterial infections without antibiotics Murphy Lam Yim Wan, Ines Ambite, Thi Hien Tran, Shahram Ahmadi, Atefeh Nazari, Arunima Chaudhuri, Farhan Haq, Christian Krintel, Björn Wullt, Florian…


Autism: How gene alteration modifies social behavior

Autism occurs in about one percent of the population and is characterized by alterations in communication, repetitive behavior and social difficulties. There are numerous genetic factors involved in the development of…


Teaching and Courses

Teaching and Courses Trainings and Workshops ELN-Wiki Introduction Process We accompany and support laboratories interested in starting to use ELN-Wiki on the way to the adoption of this new tool. A number of initial steps…


Biozentrum Discovery Seminar Series

Biozentrum Discovery Seminars Biozentrum Discovery (BZD) is a seminar series, which alternates between talks by renowned guest speakers and seminars given by graduate students and postdocs from the Biozentrum. The seminars…


Publications, curated

Publication list - curated & annotated Recent highlights Bacteria use a general danger signal to trigger biofilm formation - Nature Microbiology 2025 Mechanical properties of biofilms measured with spatial resolution -…


Targeting the PI3K/mTOR pathway in cancer, immunity and neurodegenerative disease – from scattergun approaches to highly specific covalent inhibitors

Bayesian modelling of single-cell multi-omics data The last decade has witnessed the irresistible rise of single-cell RNA-seq, a technology which can measure simultaneously the mRNA expression levels of thousands of genes in…


Claudia Keller Valsecchi

Out of the Bubble She grew up with three sisters in Pratteln. Chance led her to molecular biology. Claudia Keller Valsecchi, who once studied at the Biozentrum, has now returned as a professor. In this interview, she talks…


Projects

Evolution of viruses and bacteria We want to understand the dynamics of evolution and the forces that drive it. Evolution of plants and animals tend to happen over centuries of even longer time-scales. Microbial organisms,…


New discovery reveals how diatoms capture CO2 so effectively

Diatoms are too small to see with the naked eye, yet they are one of the most productive algae species in the ocean and play an important role in the global carbon cycle. Using photosynthesis, they absorb large amounts of…