M. tuberculosis phenotypic diversity in vivo Mycobacterium tuberculosis (Mtb) exhibits remarkable phenotypic diversity, enabling its adaptation to various host environments. The diversity of in vivo niches at granuloma,…
Newborn meningitis is one of the most dangerous childhood infections. It is often life-threatening and can cause serious and lasting damage, including developmental problems, in the children who survive. Although meningitis…
Master of Science in Physics of Life The Master's degree program in Physics of Life at the Biozentrum of the University of Basel provides training in cutting-edge research at the interface of physics, mathematics,…
About the Biozentrum What is the Biozentrum and what are its main research areas? The Biozentrum of the University of Basel is a world leading life sciences institute, with a focus on molecular and cellular biology. Find out…
The cross-border commuter May 2017 Borders are not an obstacle for her, they exist to be crossed. Kathrin Thedieck has lived at open borders since her childhood. This has shaped her self-image as a European. The fact that…
Sebastian Bolli: «You learn the most by making mistakes» Already involved in hands-on research as a bachelor’s student: Sebastian Bolli explains why the EMB course has become perhaps the most formative experience of his…
While Myc concentrations in muscle are normally low, they rise with growth stimuli, such as exercise. Based on this observation and the fact that Myc stimulates many growth processes, researchers hypothesized that Myc was…
Gene expression regulatory programs Although the genetic material is more or less identical in all cells of our body, which genes are being “read” and how they are read to produce RNAs and proteins varies between cell types.…
Michael N. Hall receives the Balzan Prize for his groundbreaking contributions to our understanding of the molecular mechanisms that regulate cell growth and ageing. Michael Hall discovered two proteins, TOR1 and TOR2, which…
TOR signaling and control of cell growth Fig. 1: Architecture of human mTOR complex 1 Introduction Cell growth is highly regulated. Cells respond to nutrients or other appropriate growth stimuli by up-regulating…
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