Role of Signal Transduction in Pathogen Persistence and Lymphocyte Survival
Our laboratory is investigating signal transduction processes that are involved in the body’s immune defense. In particular, we aim to understand how immune cells are generated and maintained in order to control pathogen invasion. In addition, we are interested in elucidating how pathogens cause disease despite the presence of a functioning immune system. The laboratory uses a variety of techniques to address these questions, including biochemistry, cell biology, imaging, as well as microbial and mouse genetics. Together this work may allow a better understanding of the host immune system as well as delineate strategies utilized by pathogens to survive and cause disease. |