Even with a greater muscle mass, a sprinter cannot win a marathon. His specially-trained and strengthened muscles will fatigue faster than the endurance-trained muscles of a long distance runner. The research group of Prof. Christoph Handschin of the Biozentrum, University of Basel could now show that during endurance exercise, the protein PGC-1α... more
The protein complex mTORC1 promotes muscle growth. However, should this complex remain constantly active, it impairs the ability of the cells to self-clean, causing myopathy. Scientists working with Markus Rüegg, Professor at the Biozentrum, University of Basel, describe the exact mechanism involved in the current issue of the scientific journal... more
| Human Cep192 and Cep152 cooperate in Plk4 recruitment and centriole duplication. Journal of cell science , 37. more |