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Insights into endolysosomal membrane homeostasis The biogenesis of endosomes and lysosomes is tightly connected to several membrane trafficking pathways from the Golgi or the plasma membrane. In addition, autophagosomes…

Cell Sorting Guidelines General information High-speed cell sorting can produce aerosols that may present a health hazard to facility members and users. The guidelines are designed to protect the users and staff of the FACS…

Structure, function, and evolution of genome-wide regulatory networks Most projects that we pursue concern the functioning and evolution of genome-wide regulatory systems in organisms ranging from bacteria to humans. The…

Evolution of viruses and bacteria We want to understand the dynamics of evolution and the forces that drive it. Evolution of plants and animals tend to happen over centuries of even longer time-scales. Microbial organisms,…

Teaching and Courses Trainings and Workshops ELN-Wiki Introduction Process We accompany and support laboratories interested in starting to use ELN-Wiki on the way to the adoption of this new tool. A number of initial steps…

LAMA2-related muscular dystrophy (LAMA2 MD; also called MDC1A) Congenital muscular dystrophies (CMDs) are a group of genetic muscle diseases with onset at birth or very early infancy. The more than 30 known forms of these…

TOR signaling and control of cell growth Fig. 1: Architecture of human mTOR complex 1 Introduction Cell growth is highly regulated. Cells respond to nutrients or other appropriate growth stimuli by up-regulating…

Biozentrum World Alumni Day, June 23, 2023 Dear Biozentrum Alumni, Do you ever wonder what your former Biozentrum colleagues and friends are up to? What is happening at the Biozentrum now? What does the new building look…

Model, Fit, and Predict the Dynamics of Life with the SSIT: The Stochastic System Identification Toolkit Stochastic modelling is important for systems whose states may experience significant fluctuations through time from…

I2: Academic Writing and Publishing in the Life Sciences - 64388 (1 hr/workshop); 2 CP; Spring 2026) Dates: to be announced Time: 9:30 - 10:30 Jan Pieter Abrahams, Marek Basler These workshops (6 x 1h plus homework) on…