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Host tissue responses to bacterial infection: A story of Mice and Men

Host tissue responses to bacterial infection: A story of Mice and Men Bacterial infection takes place in the complex microenvironment of the host tissue. Dependent on the infection type, this environment varies dramatically…


Movies

Movies Bacterial nanosized speargun Dynamics of T6SS sheath in Vibrio cholerae. (Basler et al., Nature 2012) Dueling between green Pseudomonas aeruginosa cells (ClpV-GFP) and killing of red Vibrio cholerae cells…


Spore formation in Clostridioides difficile is governed by small RNAs

Spore formation in Clostridioides difficile is governed by small RNAs Spore formation in Clostridioides difficile is governed by small RNAs - an unexpected twist on the classic model of sporulation initiation. Clostridioides…


NMJ maintenance and remodeling

NMJ maintenance and remodeling The neuromuscular junction (NMJ) is a chemical synapse that transmits motor neuron action potentials into muscle fiber action potentials (see Figure below). Without this connection, muscle…


Comparative genomics at scale in the post-AlphaFold era

Comparative genomics at scale in the post-AlphaFold era Within a decade, various consortia under the Earth BioGenome umbrella aim to sequence 1.5M eukaryotes. All these genomes are connected through life’s common origin, yet…


Kathrin Thedieck

Die Grenzgängerin Mai 2017 Grenzen sind für sie kein Hindernis, sondern zum Überschreiten da. Schon seit Kindesbeinen lebt Kathrin Thedieck an offenen Grenzen. Das hat ihr Selbstverständnis als Europäerin geprägt. Dass die…


Structural Biology, Biochemistry and Biophysics

Structural Biology, Biochemistry and Biophysics Prof. Jan Pieter Abrahams Die elementaren Strukturen des Lebens aufdecken Prof. Marek Basler Den Geheimnissen bakterieller Injektionsnadeln auf der Spur Prof. Christoph Dehio…


Molecular Medicine, Physiology, Metabolism and Aging

Molecular Medicine, Physiology, Metabolism and Aging Prof. Dirk Bumann Aktivitäten von Krankheitserregern auf Einzelzell-Ebene Prof. Christoph Dehio Molekulare Mechanismen chronisch bakterieller Infektionen Prof. Fiona…


Überblick

Technology Ventures Die molekulare und biomedizinische Grundlagenforschung am Biozentrum hat primär das Ziel, sich zentralen Fragen rund um die kleinste Einheit des Lebens, die Zelle, sowie den lebensnotwendigen Prozessen zu…


M. tuberculosis phenotypic diversity in vivo

M. tuberculosis phenotypic diversity in vivo Mycobacterium tuberculosis (Mtb) exhibits remarkable phenotypic diversity, enabling its adaptation to various host environments. The diversity of in vivo niches at granuloma,…