25 March 2026

Researchers at the Biozentrum of the University of Basel, Prof. Markus Rüegg and Dr. Judith Reinhard joined the local news station Telebasel to talk about progress and the ongoing challenges of the gene therapy they have developed to treat LAMA2-related muscular dystrophy, a currently incurable and fatal muscle disease affecting children. This gene therapy approach is being further developed by the Biozentrum spin-off SEAL Therapeutics.

Watch the TV segment here (in German):
Basler Forschende entwickeln Gentherapie gegen… | Telebasel or check out the corresponding linkedin post.

25 February 2026

Incurable muscle disease: First successes in the development of a gene therapy.
The team led by Prof. Markus Rüegg at the Biozentrum of the University of Basel has developed a gene therapy that could potentially treat a rare and currently fatal muscle disease in children. The study shows in animal models that a single treatment is sufficient to stabilize muscles and nerves and to halt disease progression. The challenge now is to bring this promising therapy into the clinic.
Read more.