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Single Particles

Applications Single particle analysis is generally used to determine the 3D structure of globular proteins and protein complexes at high resolution. Method Grids holding purified protein samples are plunge-frozen in liquid…


Equipment

Equipment Microscopes Thermo Fisher Scientific Glacios TEM FEI Tecnai G2 Spirit TEM FEI Talos F200C TEM FEI Titan Krios TEM (300kV) Thermo Fisher Scientific Versa 3D DualBeam


E7: Introduction to R

E7: Introduction to R – 48662 (2 hrs/week, 2 CP; Fall 2025, Lecture and exercises) Florian Geier, Robert Ivane k , Kloc Michal, Panagiotis Papasaikas, Julien Roux, Jenny Charlotte Soneson, Michael Stadler R is a free…


Raffiniertes Frühwarnsystem: Wie Bakterien auf Gefahren reagieren

Bei Bakterien herrscht ein ständiger Kampf ums Überleben. Überall lauern Gefahren, sei es durch Abwehrzellen unseres Körpers, Antibiotika oder Phagen – Viren, die ausschliesslich Bakterien befallen. Im Laufe der Evolution…


Pioneers

Pioneers The transcription factors that specific cell fates Our body consists of 30 trillion cells that are organized into organs such as the liver, heart and kidneys. These specialized cells are generated in the embryo by a…


Forscher entdecken neues Anti-Krebs-Protein

Die Häufigkeit von Leberkrebs, auch bekannt als Leberzellkarzinom, nimmt stetig zu. In der Schweiz hat sich die Zahl der Erkrankungen in den letzten zwanzig Jahren nahezu verdoppelt. Da diese Krebsart meist erst spät…


Purinosome: assembly mechanism and interplay with mitochondria

Purinosome: assembly mechanism and interplay with mitochondria Purinosomes represent biomolecular condensates that compartmentalize enzymes in the de novo purine synthesis (DNPS) pathway to enhance pathway flux. However, the…


The Southern Lights - Rhodopsin Complexes Discovered in an Algae Near Antarctica Can Help Unravel the Secrets of the Brain

The Southern Lights - Rhodopsin Complexes Discovered in an Algae Near Antarctica Can Help Unravel the Secrets of the Brain Rhodopsins are integral membrane proteins that bind retinal chromophores to become light sensitive.…


Hall of fame

Hall of fame Name Position Moved to Pauline Crausaz MSc student SDS Schweiz Seraina Eigenmann MSc student Merck Kazuki Nosho Postdoc Assistant Professor, University of Tokyo Takuya Ohmura Postdoc Assistant Professor,…


Growth control from cells to organisms

Growth control from cells to organisms Imbalance between the growth rate of different organs can amplify to large deviations of their size proportions during development. I will present evidence that, for the pharynx of C.…