Suche

Bayesian modelling of single-cell multi-omics data The last decade has witnessed the irresistible rise of single-cell RNA-seq, a technology which can measure simultaneously the mRNA expression levels of thousands of genes in…

From uncharted sequence space to de novo proteins From uncharted sequence space to de novo proteins Biological proteins form mostly tightly clustered families in the pool of possible combinations of canonical amino acids.…

Jadiel Wasson, Postdoc, Group Mango What is your research about? My research centers around understanding how different types of environmental inputs have intergenerational effects in a process known as epigenetic…

Emergence of globular protein folds from random amino acid sequences The origin and evolution of protein folds are among the most challenging, long-standing problems in biology. Emphasizing the challenge, evolutionary…

Free Radical Biology and Medicine Podcast Unlocking Athletic Potential: Exploring Exercise Physiology from Mechanisms to Performance Exercise training involves repeated exposure to increases in metabolic, thermal,…

Wir leben heute länger als jemals zuvor in der Geschichte der Menschheit. Um diese zusätzlichen Lebensjahre geniessen zu können, müssen wir gesund, mobil und unabhängig bleiben. Mit dem Alter jedoch büssen unsere Muskeln…

Regulators of gene expression from stem cell differentiation to aging Our group is interested in the mechanisms that control gene expression from very early to very late in human life. In eukaryotes, gene expression is a…

Uropathogenic Escherichia coli (UPEC) and urinary tract infections (UTIs) Deciphering UPEC in-vivo physiology To truly understand how UPEC behave inside the human bladder, we go straight to the source – analyzing urine…

Nuclear magnetic resonance spectroscopy of biomolecules We apply and develop high-resolution Nuclear Magnetic Resonance (NMR) methods to elucidate structure, function, and dynamics of biological macromolecules. The…

Motor circuit function Behavior is the common output of the nervous system. Despite their importance, the mechanisms by which neuronal circuits produce actions appropriately aligned with needs and intentions are poorly…