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Reuniting cell families through gene expression memory Assigning single cell transcriptomes to cellular lineage trees has transformed our understanding of differentiation during development, regeneration, and disease.…

Bacterial effectors and their many ways to modulate immune signaling Many Gram-negative bacteria modulate host immune responses through the activity of effector proteins delivered by secretion systems. The downstream changes…

DNA transfer by conjugation in live-cells DNA conjugation is a contact-dependent horizontal gene transfer mechanism responsible for the dissemination of metabolic properties in bacteria, including drug resistance. Despite…

Conformational ensembles of the human intrinsically disordered proteome Intrinsically disordered proteins and regions (collectively IDRs) are pervasive across proteomes in all kingdoms of life, help shape biological…

How to follow your passion for science while living with cerebral palsy Dr. Ilya Smolensky graduated from Saint Petersburg State University, PhD at the I. M. Sechenov Institute of Evolutionary Physiology and Biochemistry.…

New Players in the Molecular Arms Race Between Bacteria and Phages Bacteria and the viruses that infect them, bacteriophages, are locked in a fierce coevolutionary battle. The need to defend themselves against phages has…

Interview mit Karolin Berneiser Inspiriert von den Erfahrungen eines Bekannten, bewarb sich Karolin Berneiser für das «Biozentrum PhD Fellowships»-Programm. Begeistert ist sie nicht nur von den interdisziplinären und…

Conformational ensembles of the human intrinsically disordered proteome Intrinsically disordered proteins and regions (collectively IDRs) are pervasive across proteomes in all kingdoms of life, help shape biological…

Eco-evolutionary dynamics of phage-bacteria interactions Microbial communities in all environments are shaped by viral predators. Yet, resolving which viruses (phages) and bacteria are interacting, and how strongly viruses…

Of predators, vampires, and ghosts: shedding light on the lifecycles of Bdellovibriobacteria Bdellovibrio bacteriovorus is an obligate predatory bacterium that exclusively feeds upon other bacteria after invading their…