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Dynamics of the peptidoglycan synthesis machinery during Staphylococcus aureus cell division Bacterial cell division is mediated by the tubulin-homolog FtsZ which recruits peptidoglycan (PG) synthesis enzymes to the division…

Conservation of anti-viral immunity across domains of life All cells, eukaryotic and prokaryotic, face the threat of viral infections and develop anti-viral systems to fight them off. The constant arms race between cells and…

Surface tension: the battle for bacterial supremacy at the human urothelial interface Despite its initial appearance as a straightforward bacterial infection, urinary tract infection (UTI) presents a perplexing challenge, as…

Using Cryo-Electron Tomography to establish the determinants of COPII-mediated membrane remodeling COPII mediates Endoplasmic Reticulum to Golgi trafficking of thousands of cargoes. Five essential proteins assemble into a…

Navigating Ageing Through Omic Layers Ageing and its associated diseases are influenced by a complex interplay of genetics, lifestyle,environment, and increasingly recognized, the microbiome. Understanding these…

Uncovering lung injury mechanisms in COVID-19-induced ARDS using single-cell genomics The mechanistic basis of lung injury induced by SARS-CoV-2 remains poorly understood. In the most severe COVID-19 cases, patients develop…

Long read sequencing: From research to clinical Understanding the mechanism behind human diseases with an established heritable component is the next frontier in personalized medicine. Furthermore, understanding how these…

Long read sequencing: From research to clinical Understanding the mechanism behind human diseases with an established heritable component is the next frontier in personalized medicine. Furthermore, understanding how these…

Mucosal immunity in the bladder Urinary tract infections (UTI) are the second most common infection, impacting nearly 50% of all women. Indeed, otherwise healthy, premenopausal women have a significantly greater incidence of…