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Computational structure biology Protein structure modeling The main interest of our group is the development of methods and algorithms for molecular modeling and simulations of three-dimensional protein structures and their…

Cell signaling and dynamics in bacterial growth, adaptation, and persistence Our studies aim at understanding the molecular and cellular principles involved in the growth, differentiation and behavior of bacterial cells. We…

Role of type IV secretion systems in the establishment of chronic bacterial infections The aim of our studies is to gain a molecular understanding of the function of type IV secretion (T4S) systems in establishing persistent…

Motor circuit function Behavior is the common output of the nervous system. Despite their importance, the mechanisms by which neuronal circuits produce actions appropriately aligned with needs and intentions are poorly…

Nuclear magnetic resonance spectroscopy of biomolecules We apply and develop high-resolution Nuclear Magnetic Resonance (NMR) methods to elucidate structure, function, and dynamics of biological macromolecules. The…

Cell Biology Lecture Series The "Cell Biology Lecture Series" is a joint effort of the Research Groups Affolter, Engel, Hall, Hondele, Rüegg, Schier and Spang to monthly host international speakers to talk about current…