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Testimonial Jordi Lagares Mir Instituto Químico de Sarriá (IQS), Research Group Christoph Dehio Where are you from and what do you study? I am from Besalú, a small medieval town in Catalonia, Spain. After completing primary…

Conserved signals dictate symmetry braking and regeneration of multilayered epithelia Organogenesis is a highly intricate and tightly regulated process that is essential for the formation of functional organs during…

Stella Stefanova Head of the FACS Core Facility Could you briefly describe your role at the Biozentrum? I am the head of the FACS Core Facility at the Biozentrum. FACS stands for fluorescence-activated cell sorting. We work…

LAMA2-related muscular dystrophy (LAMA2 MD; also called MDC1A) Congenital muscular dystrophies (CMDs) are a group of genetic muscle diseases with onset at birth or very early infancy. The more than 30 known forms of these…

Insights into human mesoderm development from 2D gastruloids The remarkable capacity of mammalian embryos to self-organize is preserved in human pluripotent stem cells (hPSC), which on micropatterned surfaces form 2D…

Understanding the role of plasticity in the transition to a multicellular organism We are interested in understanding one of the major transitions in life, which is the origin of animal multicellularity. We hypothesize that…

Muscle aging Rapid advances in treating life-threatening, age-related diseases, such as cancer and cardiovascular disease, have extended human lifespan in many developed countries. However, greater longevity has meant more…

Muscular dystrophies Muscular dystrophies are rare, genetic diseases often caused by mutations in genes important for the structural stability of muscle fibers during contraction. As a consequence, affected children show…

Prof. Anne Spang on the relocation and recycling competence of cells Sorting out, packing, moving... All this kept Biozentrum employees busy from morning to night in the summer of 2021 and it also plays a key role in Prof.…

Prof. Anissa Kempf on sleep We do it every night and from time to time during the day, too. We sleep. But why actually? And what makes us fall asleep, how does the brain control our sleep? Prof. Anissa Kempf investigates…