SPLICECODE - Alternative Splicing Codes for Synaptic Specificity The SPLICECODE project funded by an Advanced Grant from the European Research Council explore the hypothesis that alternative splicing is a central mechanism…
NMJ maintenance and remodeling The neuromuscular junction (NMJ) is a chemical synapse that transmits motor neuron action potentials into muscle fiber action potentials (see Figure below). Without this connection, muscle…
Muscle aging Rapid advances in treating life-threatening, age-related diseases, such as cancer and cardiovascular disease, have extended human lifespan in many developed countries. However, greater longevity has meant more…
Neuronal circuit assembly in development and disease We use a multidisciplinary approach to uncover fundamental mechanisms of neural development and plasticity. We combine advanced genetic, cell biological,…
CV of Prof. Peter Scheiffele ORCID 0000-0002-9516-9399 Nationality : German Positions: Since 2008 Ordinarius für Zellbiologie und Entwicklungsbiologie Biozentrum der Universität Basel, Switzerland 2001 – 2008 Assistant…
Services & Software SWISS-MODEL A fully automated and fast protein structure homology-modelling server with the purpose of making protein modelling accessible to all life science researchers worldwide ( reference ).…
Pioneers The transcription factors that specific cell fates Our body consists of 30 trillion cells that are organized into organs such as the liver, heart and kidneys. These specialized cells are generated in the embryo by a…
Chromosomes in 3D The developmentally dynamic nucleus How are chromosomes organized within nuclei? And how does organization impact developmental events? The nucleus is very dynamic during embryogenesis, in part because…
Muscular dystrophies Muscular dystrophies are rare, genetic diseases often caused by mutations in genes important for the structural stability of muscle fibers during contraction. As a consequence, affected children show…
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