Pioneers The transcription factors that specific cell fates Our body consists of 30 trillion cells that are organized into organs such as the liver, heart and kidneys. These specialized cells are generated in the embryo by a…
Chromosomes in 3D The developmentally dynamic nucleus How are chromosomes organized within nuclei? And how does organization impact developmental events? The nucleus is very dynamic during embryogenesis, in part because…
Muscular dystrophies Muscular dystrophies are rare, genetic diseases often caused by mutations in genes important for the structural stability of muscle fibers during contraction. As a consequence, affected children show…
Epigenetic Inheritance How moms sense the environment and inform their offspring Lamarck believed that animals could respond to their environment and pass that information to their progeny independent of gene mutations.…
The Skin I Live in The forces that shape embryos, and how embryonic cells respond Embryos undergo dramatic morphogenetic movements during development. For example, C. elegans embryos begin as a compact ball of cells and…
Evolution of viruses and bacteria We want to understand the dynamics of evolution and the forces that drive it. Evolution of plants and animals tend to happen over centuries of even longer time-scales. Microbial organisms,…
Selected publications Kaur, Jakob et al , Nature 593 , 125–129 (2022) We identified the mode of action of darobactin, a natural antibiotic that inhibits the insertase BamA in Gram-negative bacteria. Darobactin binds to the…
Lab news University of Toronto March 2023 Big congratulations to Ahilya and Jadiel on their tenure track faculty job searches. Ahilya got 6 offers from 8 interviews, and will join the University of Toronto &…
CV of Prof. Dr. Susan Mango ORCID 0000-0002-2146-3237 Nationality : USA Positions: Since 2019 Professor of Cell and Developmental Biology, Biozentrum, University of Basel, Switzerland 2009 - 2019 Professor, Dept. of…
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