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Protein Filaments Applications To determine the structure of filaments and their subunits at high resolution. Method Grids holding purified filament samples are plunge-frozen in liquid ethane and imaged. The 3D structure(s)…

Cryo-FIB milling Application A specialized technique for TEM specimen preparation to mill a bulk specimen with focused gallium (Ga) ions. The target region of the specimen can be selectively thinned down to a desired shape…

Thin Sectioning Application To determine the ultrastructure of whole tissues and cells at ~2nm resolution by transmission electron microscopy (TEM). Method Tissues or cells are chemically fixed, dehydrated, embedded in resin…

Publications

FEI Titan Krios TEM (300kV) Top left: Front protective enclosure of the Titan Krios. Top right: Detail of the microscope from inside the enclosure, showing the complexity of the microscope mainframe. Bottom: Operation…

Thermo Fisher Scientific Glacios TEM Configuration 200kV X-FEG optics. C-TWIN objective lens. Autoloader for multi-grid loading at cryo-LN2 temperature and automated exchange of grid to column. The Glacios instrument is…

BioEM Lab Prices 2024 Technique Instrument University of Basel Other Academia Industry Sample prep Negative staining, Vitrobot, Leica GP, EMpact2, Resin embedding, Ultramicrotome 50 CHF/h 60 CHF/h 120 CHF/h CLEM Stellaris 8…

TFS Titan Krios G4 TEM Configuration The Titan Krios G4 from Thermo Fisher Scientific is a high-end transmission cryo-electron microscope designed for ultimate performance and productivity across a wide range of Life Science…

FEI Talos F200C TEM Configuration 200kV FEG Optics. Cryo-capable with insertable/retactable cryo box. Gatan 626 side-entry cryo holders (LN2 temperature). FEI Ceta 16M Pixel CMOS camera. STEM function. The Talos instrument…