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LAMA2-related muscular dystrophy (LAMA2 MD; also called MDC1A) Congenital muscular dystrophies (CMDs) are a group of genetic muscle diseases with onset at birth or very early infancy. The more than 30 known forms of these…

SEAL Technology The innovative gene therapy approach (called SEAL technology), developed by Prof. Markus Rüegg and Prof. Peter Yurchenco and their teams over the past 20 years, overcomes the lack of laminin-α2 in muscle…

International collaborations Founding scientists of SEAL Therapeutics (Prof. Markus A. Rüegg and Dr. Judith Reinhard) have a long-standing collaboration with Prof. Peter Yurchenco and colleagues at Rutgers, the State…

SEAL Therapeutics AG c/o Markus A. Rüegg, CEO Biozentrum, University of Basel Spitalstrasse 41 CH-4056 Basel/Switzerland markus-a.ruegg unibas ch http://www.sealtherapeutics.com/ X: @SEAL_Tx Linkedin: Seal-Therapeutics-AG …

Literature McKee KK, Yurchenco PD. Amelioration of muscle and nerve pathology of Lama2-related dystrophy by AAV9-laminin-alphaLN linker protein. JCI Insight. 2022;7(13) .

BC2 - Basel Computational Biology Seminar Series - Fall Semester 2019 16.09.2019 | Timothy Vaughan, ETH Zürich Timothy Vaughan Computational Evolution Department of Biosystems Science and Engineering, ETH Zürich Basel,…

BC2 - Basel Computational Biology Seminar Series - Spring Semester 2018 18.02.2019 | Michael Manhart, ETH Zürich Michael Manhart Institute of Integrative Biology, ETH Zürich Zürich, Schweiz High-resolution dynamics of…

Human Frontier Science Program: In search of conserved mRNA localization and anchoring mechanisms We have started a new international collaborative program with Prof. Chris Brown (University of Otago, Dunedin, New Zealand)…

CV of Prof. Dr. Markus A. Ruegg ORCID 0000-0002-4974-9384 Nationality : Swiss Positions: Since 2021 – Co-founder and CEO of SEAL Therapeutics Ltd. Weblink Since 2004 – Full Professor of Neurobiology 1998 – 2004 Associate…

CV of Prof. Dr. Richard Neher ORCID 0000-0003-2525-1407 Google Scholar Google Scholar Nationality: German Positions: Since 2017 Associate Professor, Biozentrum, University of Basel, Switzerland 2010 - 2017 Independent Max…