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Enigmatic Translons – Animalcules of Molecular Biology? Ribosome profiling has revealed the extensive utilization of multiple start codons in eukaryotic mRNAs, including in humans. Translation initiation at these start…

The Skin I Live in The forces that shape embryos, and how embryonic cells respond Embryos undergo dramatic morphogenetic movements during development. For example, C. elegans embryos begin as a compact ball of cells and…

Growth control from cells to organisms Imbalance between the growth rate of different organs can amplify to large deviations of their size proportions during development. I will present evidence that, for the pharynx of C.…

FEI Talos F200C TEM Configuration 200kV FEG Optics. Cryo-capable with insertable/retactable cryo box. Gatan 626 side-entry cryo holders (LN2 temperature). FEI Ceta 16M Pixel CMOS camera. STEM function. The Talos instrument…

Applications Single particle analysis is generally used to determine the 3D structure of globular proteins and protein complexes at high resolution. Method Grids holding purified protein samples are plunge-frozen in liquid…

Where to find information on (image) data management General Research Data Management (RDM) information: Clickable overview to all different aspects of RDM: rdmkit.elixir-europe.org Recommended Metadata for Biological…

Collective rotations in 2D and in 3D : experiments and theory Cells, tissues and organs can rotate spontaneously in vivo and in vitro. These motions are remarkable for their robustness and for their potential functions.…

TFS Titan Krios G4 TEM Configuration The Titan Krios G4 from Thermo Fisher Scientific is a high-end transmission cryo-electron microscope designed for ultimate performance and productivity across a wide range of Life Science…

Von einer, die auszog… Mai 2014 Sie hat den grossen Schritt ins Ungewisse gewagt. Biozentrum Alumna Nadine Cybulski ist vor fast drei Jahren nach Kanada ausgewandert. Ohne Job, ohne Pläne, einfach so! Warum sie sich…

Research Projects The central theme of our research is to understand how stochastic interactions of cells and molecules control the functional behaviour of multicellular systems. We specifically focus on how cells interact…