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Self-organization of active epithelial mechanics

Self-organization of active epithelial mechanics Shape changes of epithelia during animal development, such as convergent extension, are achieved through the concerted mechanical activity of individual cells. While much is…


Uncovering the hidden diversity and functional potential of bacteriophages through isolatebased research

Uncovering the hidden diversity and functional potential of bacteriophages through isolatebased research Bacteriophages, like all viruses, display remarkable diversity in the type and size of their genetic material, as well…


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Virtuelles Biozentrum Symposium 2021

Die Einschränkungen durch die Corona-Pandemie wirken sich für jeden von uns auf den Arbeitsalltag aus. Doch die Krise machte auch erfinderisch. So wurde das Biozentrum Symposium komplett auf die virtuelle Event-Plattform…


Spore formation in Clostridioides difficile is governed by small RNAs

Spore formation in Clostridioides difficile is governed by small RNAs Spore formation in Clostridioides difficile is governed by small RNAs - an unexpected twist on the classic model of sporulation initiation. Clostridioides…


Discovering new membrane protein functions with multi-scale molecular simulations

Discovering new membrane protein functions with multi-scale molecular simulations Recent breakthroughs in protein structure prediction, coupled with continuous progresses in data-intensive experimental characterization of…


Conserved signals dictate symmetry braking and regeneration of multilayered epithelia

Conserved signals dictate symmetry braking and regeneration of multilayered epithelia Organogenesis is a highly intricate and tightly regulated process that is essential for the formation of functional organs during…


Decoding the origins of mutations: From tumor signatures to germline hotspots

Decoding the origins of mutations: From tumor signatures to germline hotspots Mutations record the history of DNA damage and repair across both somatic and germline lineages. I will present two studies that uncover new…


Host manipulation by the parasite Cryptosporidium

Host manipulation by the parasite Cryptosporidium Infection by the parasite Cryptosporidium is a leading cause of child mortality, no vaccine is available and the current drug treatment against this diarrheal pathogen is…


Streamlined Montage Cryo-Electron Tomography for the Exploration of Cellular and Tissue Ultrastructure

Streamlined Montage Cryo-Electron Tomography for the Exploration of Cellular and Tissue Ultrastructure Cryo-electron tomography reveals the architecture of biological specimens at molecular resolution, albeit with a limited…