Research projects We investigate the physiology of bacterial pathogens ( Salmonella , Pseudomonas , Staphylococcus ) in infected rodent and human tissues, focusing on single-cell behavior and potential applications for novel…
Movies Bacterial nanosized speargun Dynamics of T6SS sheath in Vibrio cholerae. (Basler et al., Nature 2012) Dueling between green Pseudomonas aeruginosa cells (ClpV-GFP) and killing of red Vibrio cholerae cells…
Thermo Fisher Scientific Glacios TEM Configuration 200kV X-FEG optics. C-TWIN objective lens. Autoloader for multi-grid loading at cryo-LN2 temperature and automated exchange of grid to column. The Glacios instrument is…
Host tissue responses to bacterial infection: A story of Mice and Men Bacterial infection takes place in the complex microenvironment of the host tissue. Dependent on the infection type, this environment varies dramatically…
Spore formation in Clostridioides difficile is governed by small RNAs Spore formation in Clostridioides difficile is governed by small RNAs - an unexpected twist on the classic model of sporulation initiation. Clostridioides…
NMJ maintenance and remodeling The neuromuscular junction (NMJ) is a chemical synapse that transmits motor neuron action potentials into muscle fiber action potentials (see Figure below). Without this connection, muscle…
Comparative genomics at scale in the post-AlphaFold era Within a decade, various consortia under the Earth BioGenome umbrella aim to sequence 1.5M eukaryotes. All these genomes are connected through life’s common origin, yet…
Molecular Medicine, Physiology, Metabolism and Aging Prof. Dirk Bumann Aktivitäten von Krankheitserregern auf Einzelzell-Ebene Prof. Christoph Dehio Molekulare Mechanismen chronisch bakterieller Infektionen Prof. Fiona…
Die Grenzgängerin Mai 2017 Grenzen sind für sie kein Hindernis, sondern zum Überschreiten da. Schon seit Kindesbeinen lebt Kathrin Thedieck an offenen Grenzen. Das hat ihr Selbstverständnis als Europäerin geprägt. Dass die…
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