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DNA transfer by conjugation in live-cells DNA conjugation is a contact-dependent horizontal gene transfer mechanism responsible for the dissemination of metabolic properties in bacteria, including drug resistance. Despite…

Molecule-Scale Resolution and Dynamics in Fluorescence Microscopy I will show how an in-depth description of the basic principles of diffraction-unlimited fluorescence microscopy has spawned MINFLUX [1-4], a recent…

Publication list - curated & annotated Recent highlights Bacteria use a general danger signal to trigger biofilm formation - Nature Microbiology 2025 Mechanical properties of biofilms measured with spatial resolution -…

Cell signaling and dynamics in bacterial growth, adaptation, and persistence Our studies aim at understanding the molecular and cellular principles involved in the growth, differentiation and behavior of bacterial cells. We…

Novel strategies for treating bacterial infections without antibiotics Murphy Lam Yim Wan, Ines Ambite, Thi Hien Tran, Shahram Ahmadi, Atefeh Nazari, Arunima Chaudhuri, Farhan Haq, Christian Krintel, Björn Wullt, Florian…

Spore formation in Clostridioides difficile is governed by small RNAs Spore formation in Clostridioides difficile is governed by small RNAs - an unexpected twist on the classic model of sporulation initiation. Clostridioides…

PhD Fellows 2025 Daniil Bobrovskiy Gruppe Schier A. Gruppe Brückner D. Gruppe Schier A. Gruppe Brückner D. Biozentrum, Room: 11.Q1 daniil.bobrovskii unibas ch Leo Flehinghaus Gruppe Brückner D. Gruppe Brückner D. Biozentrum,…

Research Projects The central theme of our research is to understand how stochastic interactions of cells and molecules control the functional behaviour of multicellular systems. We specifically focus on how cells interact…

Pioneers The transcription factors that specific cell fates Our body consists of 30 trillion cells that are organized into organs such as the liver, heart and kidneys. These specialized cells are generated in the embryo by a…

Secretion of antibacterial toxins by the bacterial type VII secretion system The Type VII protein secretion system (T7SS) is found in mycobacteria and in many Gram-positive bacteria including the human pathogen…