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DNA transfer by conjugation in live-cells

DNA transfer by conjugation in live-cells DNA conjugation is a contact-dependent horizontal gene transfer mechanism responsible for the dissemination of metabolic properties in bacteria, including drug resistance. Despite…


Molecule-Scale Resolution and Dynamics in Fluorescence Microscopy

Molecule-Scale Resolution and Dynamics in Fluorescence Microscopy I will show how an in-depth description of the basic principles of diffraction-unlimited fluorescence microscopy has spawned MINFLUX [1-4], a recent…


Publications, curated

Publication list - curated & annotated Recent highlights Bacteria use a general danger signal to trigger biofilm formation - Nature Microbiology 2025 Mechanical properties of biofilms measured with spatial resolution -…


Projects

Cell signaling and dynamics in bacterial growth, adaptation, and persistence Our studies aim at understanding the molecular and cellular principles involved in the growth, differentiation and behavior of bacterial cells. We…


Projects

Research Projects The central theme of our research is to understand how stochastic interactions of cells and molecules control the functional behaviour of multicellular systems. We specifically focus on how cells interact…


PhD Fellows

PhD Fellows 2023 Aleksandr Kuznetsov Gruppe Neher R. Biozentrum, Room: 08.Q3 aleksandr.kuznetsov unibas ch Jiangning Li 3. Rotation Gruppe Diard M. Biozentrum, Room: 09.Q3 jiangning.li unibas ch Daniil Litvinov Gruppe…


Pioneers

Pioneers The transcription factors that specific cell fates Our body consists of 30 trillion cells that are organized into organs such as the liver, heart and kidneys. These specialized cells are generated in the embryo by a…


Secretion of antibacterial toxins by the bacterial type VII secretion system

Secretion of antibacterial toxins by the bacterial type VII secretion system The Type VII protein secretion system (T7SS) is found in mycobacteria and in many Gram-positive bacteria including the human pathogen…


Lab news

Lab news University of Toronto March 2023 Big congratulations to Ahilya and Jadiel on their tenure track faculty job searches. Ahilya got 6 offers from 8 interviews, and will join the University of Toronto &…


Assault, Siege, Trojan Horses or Gentle Disarmament: Molecular Strategies to Fight Bacterial Infections

Assault, Siege, Trojan Horses or Gentle Disarmament: Molecular Strategies to Fight Bacterial Infections Multidrug resistant bacterial pathogens have become a major health concern. We have investigated various chemical…