D3: Molecular and Cellular Structural Biology II – 17001

(2 hrs/week; 2 CP; Fall 2028)

Sebastian Hiller, Timm Maier

Structural Biology Across Scales - This course will provide an overview of integrative structural approaches that bridge size scales from atoms to cells.  Topics include high-resolution structure determination by techniques such as cryo-electron microscopy, resolving molecular structures within the cellular context with cryo-electron tomography, applications of AI-based structure prediction, NMR spectroscopy, structural proteomics and interactomics, whole-cell 3D imaging with volume electron microscopy and superresolution light microscopy, and computational modeling that integrates diverse structural data.

Previous lecturers*:

HS 2025:
Michael Hothorn, Geneva
Anne Schütz, München
Georg Hochberg, Marburg
Volodymyr Korkhov, PSI Villigen
Basile Wicky, ETH Zürich
Wanda Kukulski, Bern
Nenad Ban, ETH Zürich
Bruno Klaholz, Strasbourg
Johann Danzl, Austria
Matthias Hentze, Heidelberg
Florian Wollweber, Grenoble

FS 2023:
Gregor Weiss, Zürich
Mario Halic, Memphis, USA
Ashwin Chari, Göttingen
Silvija Bilokapic, Memphis, USA
Justin Kollman, Washington, USA

HS 2020:
Imre Berger, Bristol
Jonas Barandun, Umea
Michael Hennig, Villigen
Florian Schur, Austria
Alvar Gossert, Zürich
Markus Seeger, Zürich
Lisa Jones, Maryland

FS 2018:
Rebekka Wild, Zürich
Markus Seeger, Zürich
Joop van den Heuvel, Braunschweig
Frank Bernhard, Frankfurt
Holger Stark, Göttingen
Jean-Denis Pedelacq, Toulouse
Alvar Gossert, Zürich

* Order of names as per the program schedule