D4: Molecular and Cellular Structural Biology III – 17002
(2 hrs/week; 2 CP; Spring 2026)
Sebastian Hiller
This lecture series leads towards the understanding of the structural and functional aspects of biological membranes by covering broader topics of molecular structure, function, and dynamics, of both membrane and non-membrane proteins. It gives further insight into the diversity of membrane constituents and into their structural analysis by xray, nuclear magnetic resonance spectroscopy, and electron microscopy. Moreover, the thermodynamics and kinetics of lipid-protein interactions monitored by means of different biophysical techniques are discussed.
Confirmed Speakers
Prof. Dr. Camilo Perez, University of Basel
Prof. Dr. Sebastian Hiller, University of Basel
Research Director Dr. Malene Ringkjøbing Jensen, CNRS Grenoble
Prof. Dr. Oliver Einsle, Albert-Ludwigs-University Freiburg
Prof. Dr. Misha Kudryashev, Max-Delbrück-Centrum für Molekulare Medizin (MDC), Berlin
Prof. Dr. Stephan Grzesiek, University of Basel
Dr. Thomas Braun, University of Basel
Prof. Dr. Manuela Hospenthal, ETH Zürich
Dr. Valérie Panneels, Paul-Scherrer-Institute, Villigen
Prof. Dr. Ana J. García Sáez, University of Cologne
Prof. Dr. Michael Hennig, leadXpro, Villigen
Organisational Notes
This lecture series is held in a mixed format. Lectures are either held live, via live zoom or are pre-recorded and uploaded to the SWITCHtube server. The lecture series closes with students' chalk talks, which are 10-minute presentations on a chosen topic.
Schedule
Tuesdays 15:15 – 17:00, Biozentrum, 02.090 (exceptions: lectures on 10.10., 17.10. and 24.10.)
| 26.09.2023 | Prof. Dr. Camilo Perez, University of Basel (in person) |
| 03.10.2023 | Prof. Dr. Sebastian Hiller, University of Basel (in person): "β-barrel outer membrane proteins and their biogenesis" |
| 10.10.2023 | 12:15, U1.197 Research Director Dr. Malene Ringkjøbing Jensen, CNRS Grenoble (in person): "Understanding the role of intrinsic disorder in MAPK cell signaling by NMR spectroscopy" |
| 17.10.2023 | 15:15, U1.101 Prof. Dr. Oliver Einsle, Albert-Ludwigs-University Freiburg (in person): "The Architecture and Function of Nitrogenases, the Enzymes of Biological Nitrogen Fixation" |
| 24.10.2023 | 12:15, U1.197 Prof. Dr. Misha Kudryashev (in person): "Structure of membrane proteins in native membranes by cryo-EM" |
| 31.10.2023 | Prof. Dr. Stephan Grzesiek, University of Basel (in person): "Allosteric mechanisms and functional dynamics in a G protein-coupled receptor at atomic resolution" |
| 07.11.2023 | Dr. Thomas Braun, University of Basel (in person): "The cryoWriter System uniting Microfluidics and Electron Microscopy: Principles, Applications, and Results" |
| 14.11.2023 | Prof. Dr. Manuela Hospenthal, ETH Zürich (in person): "Mechanisms of DNA Uptake by Naturally Competent Bacteria" |
| 21.11.2023 | Dr. Valérie Panneels, Paul-Scherrer-Institute, Villigen (in person): "The first step of vision: ultrafast room temperature crystallography shows photoactivated membrane protein rhodopsin using an X-ray free electron laser" |
| 28.11.2023 | Prof. Dr. Ana J. García Sáez, University of Cologne (live Zoom): "Microscopy methods to study cell death mechanisms" |
| 05.12.2023 | Prof. Dr. Michael Hennig, leadXpro, Villigen (in person) |
| 12.12.2023 | Student chalk talks |
| 19.12.2023 | Student chalk talks |