D4: Molecular Structure, Function, and Dynamics of Membranes and Membrane Proteins – 17002

(2 hrs/week; 2 CP; Fall 2023)

Sebastian Hiller

Biological membranes are composed of proteins and lipids, which can both be glycosylated. Together these molecules form a functional unit. The lecture series leads towards the understanding of the structural and functional aspects of biological membranes. It gives insight into the diversity of membrane constituents and into their structural analysis by xray, nuclear magnetic resonance spectroscopy and electron microscopy. Moreover, the thermodynamics and kinetics of lipid-protein interactions monitored by means of different biophysical techniques are discussed.

Confirmed Speakers

• Prof. James Chou (Department of Biological Chemistry & Molecular Pharmacology, Harvard Medical School)
• Prof. Raimund Dutzler (Department of Biochemistry, University of Zurich)
• Prof. Robert Ernst (Institute of Medical Biochemistry and Molecular Biology, Saarland University)
• Prof. Adam Frost (Department of Biochemistry and Biophysics, University of California, San Francisco)
• Prof. Ana J. García-Sáez (CECAD Research Center, University of Cologne)
• Prof. Sebastian Hiller (Biozentrum, University of Basel)
• Prof. Syma Khalid (School of Chemistry, University of Southampton)
• Prof. Volodymyr Korkhov (Paul Scherrer Institute Villigen)
• Prof. Kaspar Locher (Institute of Molecular Biology and Biophysics, ETH Zurich)
• Dr. Alexander Mühleip (Department of Biochemistry and Biophysics, Stockholm University)
• Prof. Martin Pilhofer (Institute of Molecular Biology and Biophysics, ETH Zurich)
• Prof. Christine Ziegler (Department of Structural Biology, University of Regensburg)

Organisational Notes

Due to the COVID-19 pandemic, this lecture series is held in an interactive online format. Lectures are either held via live zoom or are pre-recorded and uploaded to the SWITCHtube server. In the latter case, students watch the lectures and then meet for a moderated discussion on the lecture content at the dates and times listed in the table below. In the discussion, the students will formulate questions and feedback, record it and send it back to the lecturer. In some cases, the lecturer will join the discussion online. The lecture series closes with students' chalk talks, which are 10-minute presentations on a chosen topic.

Schedule

Online meetings and student chalk talks are scheduled for Tuesdays 15:15 – 17:00 (exception: lecture 9)