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Aging muscles – uncovering the causes of sarcopenia

You are likely to lose around one third of your muscle mass over your lifetime. An excessive loss of muscle mass and muscle strength is known as sarcopenia. As life expectancy increases, so does the number of people…


Researchers crack a puzzle of bacterial genome evolution

The forefather of phylogenetic trees can be found in Charles Darwin's revolutionary work "On the Origin of Species". These trees provide information about the evolution and relationships of species, from simple cells to…


A bacterial toxin facilitating chronic infection

When pathogens invade our body the immune system is put on alert. The body’s immune cells are recruited to the site of infection and an inflammatory reaction is initiated to rapidly eliminate the invaders. Some pathogens,…


Farewell of Prof. Martin Spiess

A farewell event will be held on June 4, 2021, at 4 p.m. in honor of Martin Spiess, who has been Professor of Biochemistry at the Biozentrum since 1986. The program includes a welcome speech as well as words of thanks by the…


Immune defense: How immune cells are activated

T lymphocyte immune cells protect our body against pathogens. Chemokine signaling molecules direct these T cells to the site of infection where they help to eliminate the invading pathogens. This process is mediated by…


T3 Pharma: Bacterial cancer treatment on the path to enter clinical phase

According to T3 Pharmaceuticals (T3 Pharma), the funds of more than 25 million Swiss francs will be used primarily to progress the lead candidate through early clinical studies. The clinical trial in patients with solid…


Autism: How gene alteration modifies social behavior

Autism occurs in about one percent of the population and is characterized by alterations in communication, repetitive behavior and social difficulties. There are numerous genetic factors involved in the development of…


Sophisticated swarming: Bacteria support each other across generations

In nature, bacteria usually live in communities. They collectively colonize our gut, also known as the gut microbiome, or form biofilms such as dental plaque. Living in communities provides many advantages to the individual…


German pharma company acquires Biozentrum start-up for 450 million Swiss francs

T3 Pharmaceuticals (“T3 Pharma”) was founded in 2015 as a spin-off of the Biozentrum of the University of Basel. The company focuses on bacterial therapies for the treatment of solid tumors. The Basel-based biotech company’s…


New findings pave the way for hearing loss therapies

Hearing loss eventually affects almost everyone: Loud noises or simple aging gradually cause the auditory sensory cells and their synapses in the inner ear to degenerate and die off. The only treatment option is a hearing…