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Everything in balance? How a molecular switch controls lipid metabolism

All organisms need energy to live. We get energy from various components of our food. Our body uses a part of this energy directly and stores the rest. While glucose serves as an immediately available energy source, fats are…


A new layer of control in embryonic development

Genes provide the blueprint for life, determining when and where proteins are made. This process involves two key steps: transcription, from DNA to messenger mRNA (mRNA), and translation, where mRNA is decoded into proteins.…


New findings pave the way for hearing loss therapies

Hearing loss eventually affects almost everyone: Loud noises or simple aging gradually cause the auditory sensory cells and their synapses in the inner ear to degenerate and die off. The only treatment option is a hearing…


Genetic engineering in research: same same, but different

The cell envelope is covered with a wide variety of receptor proteins. They are the sensors to the environment, perceive signals such as the availability of nutrients and transmit this information to the inside of the cell.…


“The fall wave has already started”

Mr. Neher, this is our first interview without masks since the beginning of the pandemic. Will this remain so? Richard Neher: If the number of cases increases, wearing face masks again in some settings makes sense. This not…


Jordi Lagares Mir

Testimonial Jordi Lagares Mir Instituto Químico de Sarriá (IQS), Research Group Christoph Dehio Where are you from and what do you study? I am from Besalú, a small medieval town in Catalonia, Spain. After completing primary…


Laura de Smalen

Laura de Smalen, PhD Student, Group Handschin Why did you decide to do a PhD? During my bachelor's in Nutrition and Dietetics, I developed a strong interest in the causes and mechanisms that underlie the human diseases that…


Gene transfer keeps bacteria fit

Bartonella are bacteria that can cause diverse infectious diseases in man, such as cat-scratch disease. In order to prevent the accumulation of mutations during the infection cycle, pathogens require efficient DNA repair…


Cilia in 3D: Miniature train station discovered

Cilia perform numerous functions for the cell: they help cells swim, move fluid, and send messages to each other. Cilia ensure that we can see, they remove substances from the lungs, move fluid in the brain, and enable us to…


ELN: Electronic Lab Notebooks

ELN: Electronic Lab Notebooks We provide a wiki-based Electronic Lab Notebook solution (ELN-Wiki) to the research groups at the Biozentrum and other life science groups at the University of Basel. The spectrum of digital…