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Self-organization of active epithelial mechanics

Self-organization of active epithelial mechanics Shape changes of epithelia during animal development, such as convergent extension, are achieved through the concerted mechanical activity of individual cells. While much is…


RIBOncology: Decoding the regulatory RNA drivers of cancer

RIBOncology: Decoding the regulatory RNA drivers of cancer The past decade of genomics has revealed vast numbers of enigmatic non-protein coding RNAs - long noncoding RNAs (lncRNAs) – in our human genome. Many lncRNAs…


Virtual Biozentrum Symposium 2021

The restrictions resulting from the ongoing coronavirus pandemic impact each of us in our daily work. But the crisis also sparks resourcefulness. The Biozentrum Symposium, for example, was completely re-designed and moved to…


Spore formation in Clostridioides difficile is governed by small RNAs

Spore formation in Clostridioides difficile is governed by small RNAs Spore formation in Clostridioides difficile is governed by small RNAs - an unexpected twist on the classic model of sporulation initiation. Clostridioides…


Discovering new membrane protein functions with multi-scale molecular simulations

Discovering new membrane protein functions with multi-scale molecular simulations Recent breakthroughs in protein structure prediction, coupled with continuous progresses in data-intensive experimental characterization of…


Conserved signals dictate symmetry braking and regeneration of multilayered epithelia

Conserved signals dictate symmetry braking and regeneration of multilayered epithelia Organogenesis is a highly intricate and tightly regulated process that is essential for the formation of functional organs during…


Uncovering the hidden diversity and functional potential of bacteriophages through isolatebased research

Uncovering the hidden diversity and functional potential of bacteriophages through isolatebased research Bacteriophages, like all viruses, display remarkable diversity in the type and size of their genetic material, as well…


Host manipulation by the parasite Cryptosporidium

Host manipulation by the parasite Cryptosporidium Infection by the parasite Cryptosporidium is a leading cause of child mortality, no vaccine is available and the current drug treatment against this diarrheal pathogen is…


Streamlined Montage Cryo-Electron Tomography for the Exploration of Cellular and Tissue Ultrastructure

Streamlined Montage Cryo-Electron Tomography for the Exploration of Cellular and Tissue Ultrastructure Cryo-electron tomography reveals the architecture of biological specimens at molecular resolution, albeit with a limited…


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