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Relocation of proteins with a new nanobody tool

The research group of Markus Affolter is investigating the growth of the wings of the fruit fly Drosophila to understand which processes control organ development and growth. Proteins that control such growth processes are…


How bacteria reinforce their protective shield against stress

When infecting a host, pathogens not only need to evade the immune defense but also to survive diverse living conditions, such as the acidic conditions in the stomach or the salty intestinal environment. Gram negative…


Molecular bodyguards against Parkinson's disease

Parkinson's disease is one of the most common neurodegenerative disorders. In Switzerland, about 15,000 people are affected. Because of the worldwide rise in life expectancy, a rapid increase in Parkinson's cases is expected…


Sanity: Analyzing single-cell data without distortion

Although the genetic information is identical in all cells of an organism, each cell takes on its own individual state. Not only do cells come in various cell types that differ in their molecular makeup, but individual cells…


Genetic signature boosts protein production during cell division

The production of proteins is the most energy-consuming activity of cells. It needs to be tightly regulated, to ensure efficient use of cellular resources. Researchers led by Prof. Mihaela Zavolan at the Biozentrum have now…


Bacterial nanosized speargun works like a power drill

Millions of tiny microbes on leaves, stones or our skin jostle for space. And almost everywhere they have to compete for resources and nutrients. In the course of evolution, some bacteria have therefore developed a weapon to…


Designed proteins to treat muscular dystrophy

Muscular dystrophy is a term used to describe many different muscular diseases caused by genetic defects. To date, there are no treatments available to stop disease progression. In their study, the scientists led by Prof.…


Movement control: how our brain responds to unexpected situations

In mammals, movement is controlled by circuits spanning throughout the central nervous system from the cortex to the spinal cord. The role of motor cortex in the control of movement is still unclear. In humans, lesions to…


ERC Advanced Grant for Silvia Arber

The goal of the ERC Advanced Grants is to support established, leading principal investigators to pursue a groundbreaking and high-risk project. As all ERC grants, they are in high demand and therefore very competitive. This…


"Even Omicron has three variants"

There is talk about Omicron being the beginning of the end and the start of an endemic situation. What exactly does that mean? If the pandemic becomes endemic, it means that a certain balance is established between the virus…