Collective rotations in 2D and in 3D : experiments and theory Cells, tissues and organs can rotate spontaneously in vivo and in vitro. These motions are remarkable for their robustness and for their potential functions.…
Course Coordination Members Prof. Marek Basler Head Biozentrum International PhD Program Prof. Attila Becskei Program Coordinator Switzerland Trinational studies in Biotechnology Dr. Dominik Buser Course Coordinator…
In nature, bacteria usually live in communities. They collectively colonize our gut, also known as the gut microbiome, or form biofilms such as dental plaque. Living in communities provides many advantages to the individual…
T3 Pharmaceuticals (“T3 Pharma”) was founded in 2015 as a spin-off of the Biozentrum of the University of Basel. The company focuses on bacterial therapies for the treatment of solid tumors. The Basel-based biotech company’s…
Keystone gut microbiota promoting pathobiont clearance by nutrition competition and microbiota recovering The mammalian gut microbiota plays a pivotal role in various aspects of host health, ranging from nutrition, immune…
Dynamic Remodeling of Cellular Proteomes via the Ubiquitin Proteasome System Dynamic Remodeling of Cellular Proteomes via the Ubiquitin Proteasome System Description: Proteolysis stands as a cornerstone of cellular…
Capillary attraction underlies bacterial collective dynamics “Water is the driving force of all nature.” — Leonardo da Vinci Collective motion of active matter occurs in many living systems, such as bacterial communities,…
A question of dynamics In response to different stimuli many transcription factors (TFs) display different activation dynamics that trigger the expression of specific sets of target genes, suggesting that promoters have a…
Microbial pathogenesis and osteo-immunologic crosstalk during osteomyelitis Staphylococcus aureus is an important human pathogen, capable of infecting nearly all organ systems in the body. The ability of S. aureus to infect…
Conservation of anti-viral immunity across domains of life All cells, eukaryotic and prokaryotic, face the threat of viral infections and develop anti-viral systems to fight them off. The constant arms race between cells and…
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