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A “Catch-22” vaccine against Salmonellosis

Antibiotics are still the treatment of choice in fighting bacterial infections. However, due to their extensive and sometimes improper use in medicine and livestock farming, resistant pathogens are increasingly emerging,…


Overview

SEAL Therapeutics AG: Gene therapy for muscular dystrophy The Biozentrum spin-off develops an innovative gene therapy to treat congenital muscular dystrophy. Cross-section through treated LAMA2 MD muscle with individual…


Cilia in 3D: Miniature train station discovered

Cilia perform numerous functions for the cell: they help cells swim, move fluid, and send messages to each other. Cilia ensure that we can see, they remove substances from the lungs, move fluid in the brain, and enable us to…


Sacha Glardon

When biology becomes a life’s passion December 2020 He cherishes Walter Gehring’s Drosophila strains, an old PCR machine from the Biozentrum, his love for the Basel “Fasnacht” and a key to one of Basel’s old city gates, the…


Novel antibiotic deceives bacteria through mimicry

An increasing number of bacterial pathogens are resistant to antibiotics. And the most dangerous pathogens share a common feature: a double membrane that is difficult to penetrate. Even when antibiotic agents are able to…


Liver cancer: Lipid synthesis promotes tumor formation

In Switzerland, about 650 new cases of liver cancer are diagnosed every year. The incidence of the malignant and aggressive liver cell carcinoma has doubled in the last 20 years, especially in developed countries. One…


Who am I? How cells find their identity

The origin of every cell of our body is a single cell, the fertilized egg. On the way to become a specialized cell, whether blood, heart or nerve cells, its descendants follow a genetic program. This program determines the…


Teaching and Courses

Teaching and Courses Trainings and Workshops ELN-Wiki Introduction Process We accompany and support laboratories interested in starting to use ELN-Wiki on the way to the adoption of this new tool. A number of initial steps…


Autism: How gene alteration modifies social behavior

Autism occurs in about one percent of the population and is characterized by alterations in communication, repetitive behavior and social difficulties. There are numerous genetic factors involved in the development of…


RNA molecules live short lives

RNA molecules are individual transcripts of the cell’s DNA. They transfer the genetic information of the DNA and provide a template for the production of proteins that regulate all the cell’s processes. The small carriers of…