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Single Particles

Applications Single particle analysis is generally used to determine the 3D structure of globular proteins and protein complexes at high resolution. Method Grids holding purified protein samples are plunge-frozen in liquid…


E7: Introduction to R

E7: Introduction to R – 48662 (2 hrs/week, 2 CP; Fall 2025, Lecture and exercises) Florian Geier, Robert Ivane k , Kloc Michal, Panagiotis Papasaikas, Julien Roux, Jenny Charlotte Soneson, Michael Stadler R is a free…


Sophisticated early warning system: How bacteria respond to threats

Bacteria are constantly engaged in a struggle for survival, facing threats from immune cells, antibiotics, or phages— viruses that only infect bacteria. Over the course of evolution, bacteria have developed numerous…


Pioneers

Pioneers The transcription factors that specific cell fates Our body consists of 30 trillion cells that are organized into organs such as the liver, heart and kidneys. These specialized cells are generated in the embryo by a…


Researchers discover new anti-cancer protein

The incidence of liver cancer, also known as hepatocellular carcinoma, is steadily increasing. In the last twenty years, the number of cases has almost doubled in Switzerland. Hepatocellular carcinoma is usually diagnosed at…


Purinosome: assembly mechanism and interplay with mitochondria

Purinosome: assembly mechanism and interplay with mitochondria Purinosomes represent biomolecular condensates that compartmentalize enzymes in the de novo purine synthesis (DNPS) pathway to enhance pathway flux. However, the…


The Southern Lights - Rhodopsin Complexes Discovered in an Algae Near Antarctica Can Help Unravel the Secrets of the Brain

The Southern Lights - Rhodopsin Complexes Discovered in an Algae Near Antarctica Can Help Unravel the Secrets of the Brain Rhodopsins are integral membrane proteins that bind retinal chromophores to become light sensitive.…


Hall of fame

Hall of fame Name Position Moved to Pauline Crausaz MSc student SDS Schweiz Seraina Eigenmann MSc student Merck Kazuki Nosho Postdoc Assistant Professor, University of Tokyo Takuya Ohmura Postdoc Assistant Professor,…


Growth control from cells to organisms

Growth control from cells to organisms Imbalance between the growth rate of different organs can amplify to large deviations of their size proportions during development. I will present evidence that, for the pharynx of C.…


Collective rotations in 2D and in 3D : experiments and theory

Collective rotations in 2D and in 3D : experiments and theory Cells, tissues and organs can rotate spontaneously in vivo and in vitro. These motions are remarkable for their robustness and for their potential functions.…