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Single Particles

Applications Single particle analysis is generally used to determine the 3D structure of globular proteins and protein complexes at high resolution. Method Grids holding purified protein samples are plunge-frozen in liquid…


Equipment

Equipment Microscopes Thermo Fisher Scientific Glacios TEM FEI Tecnai G2 Spirit TEM FEI Talos F200C TEM FEI Titan Krios TEM (300kV) Thermo Fisher Scientific Versa 3D DualBeam


Prices

BioEM Lab Prices 2024 Technique Instrument University of Basel Other Academia Industry Sample prep Negative staining, Vitrobot, Leica GP, EMpact2, Resin embedding, Ultramicrotome 50 CHF/h 60 CHF/h 120 CHF/h CLEM Stellaris 8…


E7: Introduction to R

E7: Introduction to R – 48662 (2 hrs/week, 2 CP; Fall 2025, Lecture and exercises) Florian Geier, Robert Ivane k , Kloc Michal, Panagiotis Papasaikas, Julien Roux, Jenny Charlotte Soneson, Michael Stadler R is a free…


Sophisticated early warning system: How bacteria respond to threats

Bacteria are constantly engaged in a struggle for survival, facing threats from immune cells, antibiotics, or phages— viruses that only infect bacteria. Over the course of evolution, bacteria have developed numerous…


Pioneers

Pioneers The transcription factors that specific cell fates Our body consists of 30 trillion cells that are organized into organs such as the liver, heart and kidneys. These specialized cells are generated in the embryo by a…


Researchers discover new anti-cancer protein

The incidence of liver cancer, also known as hepatocellular carcinoma, is steadily increasing. In the last twenty years, the number of cases has almost doubled in Switzerland. Hepatocellular carcinoma is usually diagnosed at…


The Southern Lights - Rhodopsin Complexes Discovered in an Algae Near Antarctica Can Help Unravel the Secrets of the Brain

The Southern Lights - Rhodopsin Complexes Discovered in an Algae Near Antarctica Can Help Unravel the Secrets of the Brain Rhodopsins are integral membrane proteins that bind retinal chromophores to become light sensitive.…


Purinosome: assembly mechanism and interplay with mitochondria

Purinosome: assembly mechanism and interplay with mitochondria Purinosomes represent biomolecular condensates that compartmentalize enzymes in the de novo purine synthesis (DNPS) pathway to enhance pathway flux. However, the…


Hall of fame

Hall of fame Name Position Moved to Pauline Crausaz MSc student SDS Schweiz Seraina Eigenmann MSc student Merck Kazuki Nosho Postdoc Assistant Professor, University of Tokyo Takuya Ohmura Postdoc Assistant Professor,…